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  1. Article ; Online: Ghost in the machine or monkey with a typewriter-generating titles for Christmas research articles in

    Marlow, Robin / Wood, Dora

    BMJ (Clinical research ed.)

    2021  Volume 375, Page(s) e067732

    Abstract: Objective: To determine whether artificial intelligence (AI) can generate plausible and engaging titles for potential Christmas research articles in : Design: Observational study.: Setting: Europe, Australia, and Africa.: Participants: 1 AI ... ...

    Abstract Objective: To determine whether artificial intelligence (AI) can generate plausible and engaging titles for potential Christmas research articles in
    Design: Observational study.
    Setting: Europe, Australia, and Africa.
    Participants: 1 AI technology (Generative Pre-trained Transformer 3, GPT-3) and 25 humans.
    Main outcome measures: Plausibility, attractiveness, enjoyability, and educational value of titles for potential Christmas research articles in
    Results: AI generated titles were rated at least as enjoyable (159/250 responses (64%)
    Conclusions: AI can generate plausible, entertaining, and scientifically interesting titles for potential Christmas research articles in
    MeSH term(s) Artificial Intelligence ; Biomedical Research ; Humans ; Periodicals as Topic
    Language English
    Publishing date 2021-12-15
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj-2021-067732
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comparing the usability of paediatric weight estimation methods: a simulation study.

    Marlow, Robin D / Wood, Dora L B / Lyttle, Mark D

    Archives of disease in childhood

    2018  Volume 104, Issue 2, Page(s) 121–123

    Abstract: Objective: Estimating weight is essential in order to prepare appropriate sized equipment and doses of resuscitation drugs in cases where children are critically ill or injured. Many methods exist with varying degrees of complexity and accuracy. The ... ...

    Abstract Objective: Estimating weight is essential in order to prepare appropriate sized equipment and doses of resuscitation drugs in cases where children are critically ill or injured. Many methods exist with varying degrees of complexity and accuracy. The most recent version of the Advanced Paediatric Life Support (APLS) course has changed their teaching from an age-based calculation method to the use of a reference table. We aimed to evaluate the potential implications of this change.
    Method: Using a bespoke online simulation platform we assessed the ability of acute paediatric staff to apply different methods of weight estimation. Comparing the time taken, rate and magnitude of errors were made using the APLS single and triple age-based formulae, Best Guess and reference table methods. To add urgency and an element of cognitive stress, a time-based competitive component was included.
    Results: 57 participants performed a total of 2240 estimates of weight. The reference table was the fastest (25 (22-28) vs 35 (31-38) to 48 (43-51) s) and most preferred, but errors were made using all methods. There was no significant difference in the percentage accuracy between methods (93%-97%) but the magnitude of errors made was significantly smaller using the three APLS formulae 10% (6.5-21) compared with reference table (69% (34-133)) mainly from month/year table confusion.
    Conclusion: In this exploratory study under psychological stress none of the methods of weight estimation were free from error. Reference tables were the fastest method and also had the largest errors and should be designed to minimise the risk of picking errors.
    MeSH term(s) Anthropometry/methods ; Body Weight ; Child ; Computer Simulation ; Dose-Response Relationship, Drug ; Humans ; Medication Errors ; Occupational Stress ; Pediatrics ; Pharmaceutical Preparations/administration & dosage ; Reference Values ; Resuscitation ; Simulation Training ; Statistics as Topic
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2018-07-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    DOI 10.1136/archdischild-2018-314873
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Can critical care transport be safely reduced in children intubated during emergency management of status epilepticus in the United Kingdom: a national audit with case-control analysis.

    Knight, Philip / Norman, Victoria / Gully, Rochelle / Wood, Dora / Raffaj, Dusan / Riddick, Laura / Hancock, Stephen / Revanna, Sanjay / Uvaise, Mohammed / Herring, Sasha / Worrall, Mark / Daye, Ashley / Terris, Mark / O'Brien, Cormac / Kumar, Ananth / Scott, Sophie / Pritchard, Lisa / Palaniappan, Srinivasan / Hughes, Charlotte /
    Griksaitis, Michael J / Riphagen, Shelley / Ramnarayan, Padmanabhan

    Archives of disease in childhood

    2024  

    Abstract: Objective: This study describes the baseline clinical characteristics, predictors of successful extubation at referring hospitals and short-term outcomes of children intubated for status epilepticus and referred to United Kingdom (UK) paediatric ... ...

    Abstract Objective: This study describes the baseline clinical characteristics, predictors of successful extubation at referring hospitals and short-term outcomes of children intubated for status epilepticus and referred to United Kingdom (UK) paediatric critical care transport teams (PCCTs).
    Design: Multicentre audit with case-control analysis, conducted between 1 September 2018 and 1 September 2020.
    Setting: This study involved 10 UK PCCTs.
    Patients: Children over 1 month of age intubated during emergency management for status epilepticus (SE), referred to UK PCCTs. Patients with trauma, requiring time-critical neurosurgical intervention or those with a tracheostomy were excluded.
    Interventions: No interventions were implemented.
    Measurements and main results: Out of the 1622 referrals for SE, 1136 (70%) were intubated at referral. The median age was 3 years (IQR 1.25-6.54 years). Among the intubated children, 396 (34.8%) were extubated locally by the referring team, with 19 (4.8%) requiring reintubation. Therefore, the overall rate of successful extubation was 33% (377/1136). There was significant variation between PCCTs, with local extubation rates ranging from 2% to 74%. Multivariable analyses showed region/PCCT, contributing diagnosis, acute changes on CT, preceding encephalopathy and type of continuous sedation (midazolam) used postintubation were significantly associated with transfer to a critical care unit.
    Conclusion: This study highlights wide regional variation in early extubation practices. Regions with high successful extubation rates have established extubation guidelines from PCCTs. Successful extubation represents critical care transports that have been avoided.
    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    DOI 10.1136/archdischild-2023-326320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Complementary and alternative medicine use in children with life-limiting conditions.

    Wood, Dora / Finlay, Fiona

    Nursing children and young people

    2011  Volume 23, Issue 4, Page(s) 31–34

    Abstract: Aim: To quantify use of complementary and alternative medicine (CAM) in children with non-malignant, life-limiting illness.: Method: A self-administered questionnaire was sent to families who received care from a community children's nursing and ... ...

    Abstract Aim: To quantify use of complementary and alternative medicine (CAM) in children with non-malignant, life-limiting illness.
    Method: A self-administered questionnaire was sent to families who received care from a community children's nursing and psychology team for children with non-malignant, life-limiting conditions.
    Results: A total of 32 per cent of respondents had used up to seven types of CAM for their child and 43.4 per cent had used CAM for themselves or other family members. Most parents used CAM to enhance general wellbeing rather than treat specific diagnoses. A total of 58.3 per cent felt the therapy was helpful, 50 per cent had tried conventional medicine first, and 63.9 per cent of users discussed their use of CAM with a doctor or community nurse.
    Conclusion: The rate of CAM use is significantly higher in this population than found in many previous cross-sectional studies. This may reflect the different needs and expectations of families with children with non-malignant, life-limiting illnesses.
    MeSH term(s) Complementary Therapies/utilization ; Humans ; Surveys and Questionnaires ; United Kingdom
    Language English
    Publishing date 2011-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2603456-6
    ISSN 2046-2336
    ISSN 2046-2336
    DOI 10.7748/ncyp2011.05.23.4.31.c8490
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Characteristics of adolescents requiring intensive care in the United Kingdom: A retrospective cohort study.

    Wood, Dora / Goodwin, Sarah / Pappachan, John / Davis, Peter / Parslow, Roger / Harrison, David / Ramnarayan, Padmanabhan

    Journal of the Intensive Care Society

    2018  Volume 19, Issue 3, Page(s) 209–213

    Abstract: Objectives: To describe the case mix, resource use and outcomes for adolescents admitted to intensive care units in the UK.: Methods: Analysis of national prospectively collected data for all adolescents aged 12-19 years admitted to UK adult or ... ...

    Abstract Objectives: To describe the case mix, resource use and outcomes for adolescents admitted to intensive care units in the UK.
    Methods: Analysis of national prospectively collected data for all adolescents aged 12-19 years admitted to UK adult or paediatric intensive care units.
    Results: There were 37,320 admissions of adolescents during the eight-year study period. Excluding elective surgery, respiratory diagnoses were the most common reason for paediatric intensive care unit (PICU) admission, with trauma and intoxication the most common reasons for adult intensive care unit (AICU) admission. Intensive care unit mortality was 6.0% and 5.7% for those admitted to PICUs and AICUs, respectively.
    Conclusions: Mortality is similar among adolescents admitted to AICUs and PICUs; however, these rates have not been corrected for severity of acute illness or underlying burden of chronic illness, which may be different between AICUs and PICUs. Services planned for the majority of AICU and PICU patients may not be optimal for critically ill adolescents treated in UK intensive care units, who may need special consideration.
    Language English
    Publishing date 2018-01-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2701626-2
    ISSN 1751-1437 ; 1751-1437
    ISSN (online) 1751-1437
    ISSN 1751-1437
    DOI 10.1177/1751143717746047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Doctors' knowledge of tissue donation in children.

    Wood, Dora / Finlay, Fiona

    Archives of disease in childhood

    2010  Volume 95, Issue 11, Page(s) 926–927

    Abstract: Objective: To find out whether doctors who work with children have a basic knowledge of tissue and organ donation which would allow them to initiate discussions with families.: Methods: Anonymous self-completed questionnaire containing basic ... ...

    Abstract Objective: To find out whether doctors who work with children have a basic knowledge of tissue and organ donation which would allow them to initiate discussions with families.
    Methods: Anonymous self-completed questionnaire containing basic information about donation administered to 56 doctors working in paediatrics, emergency medicine and intensive care in one district general hospital.
    Results: 89% doctors were aware that children could donate solid organs after death although 39.3% thought incorrectly that premature babies were eligible. Respondents were generally less knowledgeable about age limits for tissue (heart valve and eye), blood and bone marrow donation. The overall average score on the questionnaire was only 49.9%, this score did not vary with grade or paediatric training.
    Conclusion: Participants had poor knowledge about tissue and organ donation, which would make approaching families difficult. This study has identified an important training need for all doctors involved in the care of dying children.
    MeSH term(s) Adolescent ; Age Factors ; Child ; Child, Preschool ; Clinical Competence ; England ; Hospitals, District ; Hospitals, General ; Humans ; Infant ; Infant, Newborn ; Medical Staff, Hospital/standards ; Tissue and Organ Procurement
    Language English
    Publishing date 2010-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    DOI 10.1136/adc.2009.166363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Where Should Critically Ill Adolescents Receive Care? A Qualitative Interview-Based Study of Perspectives of Staff Working in Adult and Pediatric Intensive Care Units.

    Wood, Dora / Geoghegan, Sophie / Ramnarayan, Padmanabhan / Davis, Peter J / Tume, Lyvonne / Pappachan, John V / Goodwin, Sarah / Wray, Jo

    Journal of intensive care medicine

    2019  Volume 35, Issue 11, Page(s) 1271–1277

    Abstract: Purpose: In the United Kingdom, critically ill adolescents are treated in either adult or pediatric intensive care units (AICUs or PICUs). This study explores staff perspectives on where and how best to care for this distinct group.: Materials and ... ...

    Abstract Purpose: In the United Kingdom, critically ill adolescents are treated in either adult or pediatric intensive care units (AICUs or PICUs). This study explores staff perspectives on where and how best to care for this distinct group.
    Materials and methods: Semistructured interviews were conducted with 12 members of staff (3 medical, 6 nursing, and 3 allied health professionals) working in 4 ICUs; 2 general hospital AICUs and 2 tertiary centre-based PICUs in England. Interviews were audio-recorded, transcribed, and analyzed using framework analysis.
    Findings: One overarching theme was identified, reflecting staff understanding of the term "adolescent," and this was linked to 2 further themes, each of which had several subthemes. "Needs of the critically ill adolescent" included medical needs, dignity and privacy, issues around consent, and the impact of intensive care admission. "Implications for staff" included managing parental presence and lack of familiarity, and emotional impact, of dealing with this patient group. Some of these factors are currently better accommodated in adult settings.
    Conclusions: Decision-making about the place of care should take into account the individual circumstances of the patient (e.g., nature of their medical condition and previous experiences, maturity, family preference) and not be based only on age at admission. We should work across disciplines to ensure we can discover, and consistently deliver, best practice to meet the needs of critically ill adolescents.
    MeSH term(s) Adolescent ; Adult ; Child ; Critical Care ; Critical Illness/therapy ; Hospitalization ; Humans ; Intensive Care Units ; Intensive Care Units, Pediatric ; Qualitative Research
    Language English
    Publishing date 2019-06-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632828-3
    ISSN 1525-1489 ; 0885-0666
    ISSN (online) 1525-1489
    ISSN 0885-0666
    DOI 10.1177/0885066619856573
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Tracheostomy in children admitted to paediatric intensive care.

    Wood, Dora / McShane, Philip / Davis, Peter

    Archives of disease in childhood

    2012  Volume 97, Issue 10, Page(s) 866–869

    Abstract: Purpose: Tracheostomy is a common intervention for adults admitted to intensive care; many are performed early and most are percutaneous. Our study aimed to elucidate current practice and indications for children in the UK admitted to paediatric ... ...

    Abstract Purpose: Tracheostomy is a common intervention for adults admitted to intensive care; many are performed early and most are percutaneous. Our study aimed to elucidate current practice and indications for children in the UK admitted to paediatric intensive care and undergoing tracheostomy.
    Design: A questionnaire covering unit guidelines, practice, and the advantages and disadvantages of tracheostomy was sent to all UK paediatric intensive care units (PICUs) participating in the Paediatric Intensive Care Audit Network (PICANet). These results were combined with data from PICANet on all children in the UK reported to have had a tracheostomy performed during a PICU admission between 2005 and 2009 inclusive.
    Results: Over 5 years, 1613 children had tracheostomies performed during their PICU admission (2.05% of all admissions). The death rate was 5.58% with tracheostomy versus 4.72% overall, but differences were not significant when risk-adjusted using the Paediatric Index of Mortality 2 (PIM2). All 29 units participating in PICANet responded to the survey. Prolonged invasive ventilation was an indication for tracheostomy in 25/29 units, but the definition varied between 14 and 90 days, and most respondents considered timing on an individual basis. Children undergoing tracheostomy during PICU admission account for 9% of PICU bed days in the UK.
    Conclusions: In contrast with current adult UK practice, tracheostomy for children admitted to intensive care is infrequent, performed late following admission and usually surgical. Practice varies significantly. The death rate for children having a tracheostomy performed was not significantly higher than for children admitted to PICU who did not undergo tracheostomy.
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Female ; Hospitalization/statistics & numerical data ; Humans ; Infant ; Intensive Care Units, Pediatric/statistics & numerical data ; Male ; Surveys and Questionnaires ; Tracheostomy/methods ; Tracheostomy/mortality ; Tracheostomy/standards ; Treatment Outcome ; United Kingdom
    Language English
    Publishing date 2012-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    DOI 10.1136/archdischild-2011-301494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Eliciting the experiences of the adolescent-parent dyad following critical care admission: a pilot study.

    Wood, Dora / Geoghegan, Sophie / Ramnarayan, Padmanabhan / Davis, Peter J / Pappachan, John V / Goodwin, Sarah / Wray, Jo

    European journal of pediatrics

    2018  Volume 177, Issue 5, Page(s) 747–752

    Abstract: Critically ill adolescents are usually treated on intensive care units optimised for much older adults or younger children. The way they access and experience health services may be very different to most adolescent service users, and existing quality ... ...

    Abstract Critically ill adolescents are usually treated on intensive care units optimised for much older adults or younger children. The way they access and experience health services may be very different to most adolescent service users, and existing quality criteria may not apply to them. The objectives of this pilot study were, firstly, to determine whether adolescents and their families were able to articulate their experiences of their critical care admission and secondly, to identify the factors that are important to them during their intensive care unit (ICU) or high dependency unit (HDU) stay. Participants were 14-17 year olds who had previously had an emergency admission to an adult or paediatric ICU/HDU in one of four UK hospitals (two adult, two paediatric) and their parents. Semi-structured interviews were conducted with eight mother-adolescent dyads and one mother. Interviews were transcribed and analysed using framework analysis.
    Conclusion: The main reported determinant of high-quality care was the quality of interaction with staff. The significance of these interactions and their environment depended on adolescents' awareness of their surroundings, which was often limited in ICU and changed significantly over the course of their illness. Qualitative interview methodology would be difficult to scale up for this group. What is known • Critically ill adolescents are usually treated on intensive care units optimised for older adults or younger children. • The way they access and experience health services may be different to most adolescent patients; existing quality criteria may not apply. What is new • Reported determinants of high-quality care were age-appropriateness of the environment, respectfulness and friendliness of staff, communication and inclusion in healthcare decisions. • The significance of these depended on adolescents' awareness of their surroundings, which was often limited and changed over the course of their illness.
    MeSH term(s) Adolescent ; Attitude to Health ; Critical Care/methods ; Critical Care/psychology ; Critical Illness/psychology ; Critical Illness/therapy ; Female ; Hospitalization/statistics & numerical data ; Humans ; Intensive Care Units ; Male ; Parents/psychology ; Patient Satisfaction/statistics & numerical data ; Pilot Projects ; Professional-Patient Relations ; Qualitative Research ; Quality of Health Care/statistics & numerical data ; United Kingdom
    Language English
    Publishing date 2018-02-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 194196-3
    ISSN 1432-1076 ; 0340-6199 ; 0943-9676
    ISSN (online) 1432-1076
    ISSN 0340-6199 ; 0943-9676
    DOI 10.1007/s00431-018-3117-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Vision out of the corner of the eye.

    To, M P S / Regan, B C / Wood, Dora / Mollon, J D

    Vision research

    2011  Volume 51, Issue 1, Page(s) 203–214

    Abstract: The margin of the temporal visual field lies more than 90° from the line of sight and is critical for detecting incoming threats and for balance and locomotive control. We show (i) contrast sensitivity beyond 70° is higher for moving stimuli than for ... ...

    Abstract The margin of the temporal visual field lies more than 90° from the line of sight and is critical for detecting incoming threats and for balance and locomotive control. We show (i) contrast sensitivity beyond 70° is higher for moving stimuli than for stationary, and in the outermost region, only moving stimuli are visible; (ii) sensitivity is highest for motion in directions near the vertical and horizontal axes and is higher for forward than for backward directions; (iii) the former anisotropy arises early in the visual pathway; (iv) thresholds for discriminating direction are lowest for upward and downward motion.
    MeSH term(s) Contrast Sensitivity/physiology ; Discrimination (Psychology) ; Female ; Humans ; Male ; Motion Perception/physiology ; Photic Stimulation ; Sensory Thresholds/physiology ; Visual Fields/physiology ; Visual Perception/physiology
    Language English
    Publishing date 2011-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 200427-6
    ISSN 1878-5646 ; 0042-6989
    ISSN (online) 1878-5646
    ISSN 0042-6989
    DOI 10.1016/j.visres.2010.11.008
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