LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 6 of total 6

Search options

  1. Article ; Online: In vivo

    Houlihan, Orla Anne / Workman, Geraldine / Hounsell, Alan R / Prise, Kevin M / Jain, Suneil

    The British journal of radiology

    2022  Volume 95, Issue 1137, Page(s) 20220046

    Abstract: Advances in knowledge: This paper describes the potential role ... ...

    Abstract Advances in knowledge: This paper describes the potential role for
    MeSH term(s) Brachytherapy ; Humans ; In Vivo Dosimetry ; Radiometry ; Radiotherapy Dosage ; Uncertainty
    Language English
    Publishing date 2022-08-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1259/bjr.20220046
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.11: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Mass-manufacturable scintillation-based optical fiber dosimeters for brachytherapy.

    Gierej, Agnieszka / Baghdasaryan, Tigran / Martyn, Michael / Woulfe, Peter / Mc Laughlin, Owen / Prise, Kevin / Workman, Geraldine / O'Keeffe, Sinead / Rochlitz, Kurt / Verlinski, Sergey / Giaz, Agnese / Santoro, Romualdo / Caccia, Massimo / Berghmans, Francis / Van Erps, Jürgen

    Biosensors & bioelectronics

    2024  Volume 255, Page(s) 116237

    Abstract: Scintillation-based fiber dosimeters are a powerful tool for minimally invasive localized real-time monitoring of the dose rate during Low Dose Rate (LDR) and High Dose Rate (HDR) brachytherapy (BT). This paper presents the design, fabrication, and ... ...

    Abstract Scintillation-based fiber dosimeters are a powerful tool for minimally invasive localized real-time monitoring of the dose rate during Low Dose Rate (LDR) and High Dose Rate (HDR) brachytherapy (BT). This paper presents the design, fabrication, and characterization of such dosimeters, consisting of scintillating sensor tips attached to polymer optical fiber (POF). The sensor tips consist of inorganic scintillators, i.e. Gd
    MeSH term(s) Radiation Dosimeters ; Brachytherapy ; Optical Fibers ; Biosensing Techniques ; Polymers
    Chemical Substances Polymers
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1011023-9
    ISSN 1873-4235 ; 0956-5663
    ISSN (online) 1873-4235
    ISSN 0956-5663
    DOI 10.1016/j.bios.2024.116237
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2275: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: UK & Ireland Prostate Brachytherapy Practice Survey 2014-2016.

    Corey, Gemma / Yoosuf, A B Mohamed / Workman, Geraldine / Byrne, Monica / Mitchell, Darren M / Jain, Suneil

    Journal of contemporary brachytherapy

    2018  Volume 10, Issue 3, Page(s) 238–245

    Abstract: Purpose: To document the current prostate brachytherapy practice across the UK and Ireland and compare with previously published audit results.: Material and methods: Participants from 25 centers attending the annual UK & Ireland Prostate ... ...

    Abstract Purpose: To document the current prostate brachytherapy practice across the UK and Ireland and compare with previously published audit results.
    Material and methods: Participants from 25 centers attending the annual UK & Ireland Prostate Brachytherapy Conference were invited to complete an online survey. Sixty-three questions assessed the center's experience and staffing, clinician's experience, clinical selection criteria and scheduling, number of cases per modality in the preceding three years, low-dose-rate (LDR) pre- and post-implant technique and high-dose-rate (HDR) implant technique. Responses were collated, and descriptive statistical analysis performed.
    Results: Eighteen (72%) centers responded with 17 performing LDR only, 1 performing HDR only, and 6 performing both LDR and HDR. Seventy-one percent of centers have > 10 years of LDR brachytherapy experience, whereas 71% centers that perform HDR brachytherapy have > 5 years of experience. Thirteen centers have 2 or more clinicians performing brachytherapy with 61% of lead consultants performing > 25 cases (LDR + HDR) in 2016. The number of implants (range), that includes LDR and HDR, performed by individual practitioners in 2016 was > 50 by 21%, 25-50 by 38%, and < 25 by 41%. Eight centers reported a decline in LDR monotherapy case numbers in 2016. Number of center's performing HDR brachytherapy increased in last five years. Relative uniformity in patient selection is noted, and LDR pre- and post-implant dosimetry adheres to published quality guidelines, with an average post-implant D
    Conclusion: There is considerable prostate brachytherapy experience in the UK and Ireland. An apparent fall in LDR case numbers is noted. Maintenance of case numbers and ongoing compliance with published quality guidelines is important to sustain high quality outcomes.
    Language English
    Publishing date 2018-06-29
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 2627721-9
    ISSN 2081-2841 ; 1689-832X
    ISSN (online) 2081-2841
    ISSN 1689-832X
    DOI 10.5114/jcb.2018.76839
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Verification of high-dose-rate brachytherapy treatment planning dose distribution using liquid-filled ionization chamber array.

    Mohamed Yoosuf, A B / Jeevanandam, Prakash / Whitten, Glenn / Workman, Geraldine / McGarry, Conor K

    Journal of contemporary brachytherapy

    2018  Volume 10, Issue 2, Page(s) 142–154

    Abstract: Purpose: This study aims to investigate the dosimetric performance of a liquid-filled ionization chamber array in high-dose-rate (HDR) brachytherapy dosimetry. A comparative study was carried out with air-filled ionization chamber array and EBT3 ... ...

    Abstract Purpose: This study aims to investigate the dosimetric performance of a liquid-filled ionization chamber array in high-dose-rate (HDR) brachytherapy dosimetry. A comparative study was carried out with air-filled ionization chamber array and EBT3 Gafchromic films to demonstrate its suitability in brachytherapy.
    Material and methods: The PTW OCTAVIUS detector 1000 SRS (IA 2.5-5 mm) is a liquid-filled ionization chamber array of area 11 x 11 cm
    Results: The mean point dose differences between measured and calculated plans were 0.2% ± 1.6%, 1.8% ± 1.0%, and 1.5% ± 0.81% for film, IA 10 mm, and IA 2.5-5 mm, respectively. The average percentage of passed gamma (global/local) values using 3%/3 mm criteria was above 99.8% for all three detectors on the original plan. For IA 2.5-5 mm, local gamma criteria of 2%/1 mm with a passing rate of at least 95% was found to be sensitive when simulated positional errors of 1 mm was introduced.
    Conclusion: The dosimetric properties of IA 2.5-5 mm showed the applicability of liquid-filled ionization chamber array as a potential QA device for HDR brachytherapy treatment planning systems.
    Language English
    Publishing date 2018-04-30
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2627721-9
    ISSN 2081-2841 ; 1689-832X
    ISSN (online) 2081-2841
    ISSN 1689-832X
    DOI 10.5114/jcb.2018.75599
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Sector analysis provides additional spatial information on the permanent prostate brachytherapy learning curve.

    Mohamed Yoosuf, Ahamed Badusha / Mitchell, Darren M / Workman, Geraldine / Jonnada, Sai / Napier, Eoin / Jain, Suneil

    Brachytherapy

    2015  Volume 14, Issue 5, Page(s) 703–710

    Abstract: Purpose: To evaluate the permanent prostate brachytherapy (PPB) learning curve using postimplant multisector dosimetric analysis and to assess the correlation between sector -specific dosimetry and patient-reported outcome measures (PROMs).: Methods ... ...

    Abstract Purpose: To evaluate the permanent prostate brachytherapy (PPB) learning curve using postimplant multisector dosimetric analysis and to assess the correlation between sector -specific dosimetry and patient-reported outcome measures (PROMs).
    Methods and methods: First 200 patients treated with (125)I PPB monotherapy (145 Gy) at a single institution were assessed. Postimplant dosimetry (PID) using CT was evaluated for whole prostate (global) and 12 sectors, assessing minimum dose to 90% of prostate (D90) and dose to 0.1 cm(3) of rectum (D0.1cc). Global and sector PID results were evaluated to investigate changes in D90 with case number. Urinary and bowel PROMs were assessed using the International Prostate Symptom Score and the Expanded Prostate Cancer Index Composite questionnaire. The correlation between global and individual sector PID and urinary/bowel PROMs was also evaluated.
    Results: Linear regression confirmed a significant improvement in global D90 with case number (r(2) = 0.20; p = 0.001) at a rate of 0.11 Gy/case. Postimplant D90 of base sectors increased at a rate of 0.11-0.15 Gy/case (p = 0.0001) and matched global improvement. The regression lines of midgland and apex sectors were significantly different from global D90 (p = 0.01). Posterior midgland sectors showed a significant reduction in D90 with case number at a rate of 0.13-0.19 Gy/case (p = 0.01). Dose to posterior midgland sectors correlated with rectal D0.1cc dose but not bowel PROMs. Dose to posterior midgland sectors correlated with urinary International Prostate Symptom Score change, which was not apparent when global D90 alone was considered.
    Conclusions: Sector analysis provided increased spatial information regarding the PPB learning curve. Furthermore, sector analysis correlated with urinary PROMs and rectal dose.
    MeSH term(s) Adult ; Aged ; Brachytherapy/methods ; Humans ; Iodine Radioisotopes/therapeutic use ; Learning Curve ; Male ; Middle Aged ; Prostatic Neoplasms/complications ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/radiotherapy ; Prostatism/etiology ; Radiation Dosage ; Radiometry/methods ; Radiotherapy Dosage ; Rectum/radiation effects ; Severity of Illness Index ; Tomography, X-Ray Computed
    Chemical Substances Iodine Radioisotopes
    Language English
    Publishing date 2015-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2098608-7
    ISSN 1873-1449 ; 1538-4721
    ISSN (online) 1873-1449
    ISSN 1538-4721
    DOI 10.1016/j.brachy.2015.05.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6116: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Sector analysis of 125I permanent prostate brachytherapy provides a rapid and effective method of evaluating and comparing pre- and post-implant dosimetry.

    Mohamed Yoosuf, Ahamed Badusha / Workman, Geraldine / O'Toole, Monica M / Straney, Margaret / Verghis, Rejina / Napier, Eoin / Mitchell, Darren M

    Brachytherapy

    2013  Volume 12, Issue 3, Page(s) 254–259

    Abstract: Purpose: To evaluate a sector analysis program in the assessment and comparison of pre- and post-implant dosimetric parameters during the development of an (125)I permanent prostate brachytherapy service.: Methods and materials: A total of 50 ... ...

    Abstract Purpose: To evaluate a sector analysis program in the assessment and comparison of pre- and post-implant dosimetric parameters during the development of an (125)I permanent prostate brachytherapy service.
    Methods and materials: A total of 50 consecutive men being treated with permanent prostate brachytherapy had dose-volume analysis in 12 sectors of their pre-implant ultrasound (USpre) and post-implant CT (CTpost) studies. Individual sectors were created by dividing prostate into three equal lengths, namely base, midgland, and apex. Each of these volumes was then divided into four axial sectors. Dosimetric parameters were compared in adjoining sectors within each study and between studies.
    Results: There were statistically significant differences between individual sectors on USpre and CTpost volumes with CTpost higher than USpre (p=0.001). Statistically significant differences were found in corresponding sectors on USpre and CTpost for all dosimetric parameters. The dosimetric parameters were significantly lower on CTpost in the anterior base and midgland (p=0.001) and significantly higher at the posterior apex and midgland (p=0.05). Dose homogeneity was demonstrated in adjoining sectors in all USpre and most adjoining sectors on CTpost.
    Conclusions: Sector analysis allows rapid assessment of USpre and CTpost dosimetry. It offers a scientific method of identifying areas of increased and reduced dosing on CTpost when compared with USpre, providing a learning tool to refine dosimetric analysis and highlight sectors where implant quality could be improved.
    MeSH term(s) Aged ; Brachytherapy/methods ; Data Interpretation, Statistical ; Follow-Up Studies ; Humans ; In Vitro Techniques ; Iodine Radioisotopes/therapeutic use ; Male ; Middle Aged ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/radiotherapy ; Radiotherapy Dosage ; Retrospective Studies ; Tomography, X-Ray Computed ; Treatment Outcome
    Chemical Substances Iodine Radioisotopes
    Language English
    Publishing date 2013-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2098608-7
    ISSN 1873-1449 ; 1538-4721
    ISSN (online) 1873-1449
    ISSN 1538-4721
    DOI 10.1016/j.brachy.2012.08.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6116: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top