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  1. Book ; Online ; E-Book: Cancer epidemiology among Asian Americans

    Wu, Anna H. / Stram, Daniel O.

    2016  

    Author's details Anna H. Wu, Daniel O. Stram editors
    Keywords Medicine ; Cancer research ; Epidemiology
    Subject code 614.5999
    Language English
    Size 1 Online-Ressource (XI, 292 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019442253
    ISBN 978-3-319-41118-7 ; 9783319411163 ; 3-319-41118-7 ; 3319411160
    DOI 10.1007/978-3-319-41118-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Green tea and cancer

    Wu, Anna H.

    (Molecular nutrition & food research ; 55,6)

    2011  

    Title variant Special: Green tea and cancer
    Author's details guest ed.: Anna H. Wu
    Series title Molecular nutrition & food research ; 55,6
    Collection
    Language English
    Size S. 817 - 963 : Ill., graph. Darst.
    Publisher Wiley-VCH
    Publishing place Weinheim
    Publishing country Germany
    Document type Book
    HBZ-ID HT016868923
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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  3. Article: Effect of Chemotherapy on the Gut Microbiome of Breast Cancer Patients During the First Year of Treatment.

    Wu, Anna H / Vigen, Cheryl / Tseng, Chiuchen / Garcia, Agustin A / Spicer, Darcy

    Breast cancer (Dove Medical Press)

    2022  Volume 14, Page(s) 433–451

    Abstract: Introduction: There is accumulating information of the effects of chemotherapy and weight changes on the gut microbiome of breast cancer patients.: Methods: In this 1-year follow-up study, we investigated gut microbiome of 33 breast cancer patients ... ...

    Abstract Introduction: There is accumulating information of the effects of chemotherapy and weight changes on the gut microbiome of breast cancer patients.
    Methods: In this 1-year follow-up study, we investigated gut microbiome of 33 breast cancer patients who donated fecal samples at baseline and after completion of treatment. We compared alpha diversity and mean taxa abundance at baseline and absolute taxa abundance changes (final-baseline) by treatment (16 neoadjuvant [neoADJ], 13 adjuvant [ADJ], 4 no chemotherapy [noC]) and specific chemotherapy agent using Wilcoxon rank sum and negative binomial mixed model (NBMM) analysis.
    Results: All four gut alpha diversity measures changed in association with chemotherapy treatment; they increased in the neoADJ (+16.4% OTU
    Conclusion: Results from this pilot longitudinal study support an effect of chemotherapy, particularly neoADJ on the gut microbiome of breast cancer patients even after adjustment for weight changes. Further investigations are needed to confirm these findings in larger studies and with longer follow-up and to assess the impact of these microbiome changes on patient outcome.
    Language English
    Publishing date 2022-12-09
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2520722-2
    ISSN 1179-1314
    ISSN 1179-1314
    DOI 10.2147/BCTT.S305486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Thesis: A case-control study of lung cancer in women

    Wu, Anna H.

    1983  

    Author's details by Anna Hing-Tong Wu
    Size XV, 192 S. : graph. Darst.
    Publishing country United States
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Los Angeles, Calif., Univ. of California, Diss., 1983
    HBZ-ID HT002263457
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: The Association of Alcohol Outlet Density with Alcohol Intake: The Multiethnic Cohort.

    Acuna, Nicholas / Shariff-Marco, Salma / Wu, Anna H / Meltzer, Dan / Inamdar, Pushkar / Lim, Tiffany / Marchand, Loïc Le / Haiman, Christopher A / Wilkens, Lynne R / Cheng, Iona / Setiawan, Veronica Wendy

    Journal of studies on alcohol and drugs

    2024  

    Abstract: Objective: Neighborhood characteristics have been shown to influence lifestyle behaviors. Here we characterized alcohol outlet density in Los Angeles County, California, and Hawaii and assessed the association of alcohol outlet density with self- ... ...

    Abstract Objective: Neighborhood characteristics have been shown to influence lifestyle behaviors. Here we characterized alcohol outlet density in Los Angeles County, California, and Hawaii and assessed the association of alcohol outlet density with self-reported alcohol intake in the Multiethnic Cohort.
    Method: Participants (n=178,977) had their addresses geocoded, at cohort entry (1993-1996), and appended to block group-level alcohol outlet densities (on- and off-premises). Multinomial logistic regression was performed to assess the association between self-reported alcohol intake and on- and off-premise alcohol outlet densities by each state. Stratified analysis was conducted by sex, race, and ethnicity.
    Results: Overall, we did not find associations between alcohol outlet density and self-reported alcohol intake in Los Angeles County, but we found that on-premise alcohol outlets were associated with 59% (OR=1.59, 95% CI:1.29,1.96) increased odds of consuming >2 drinks per day in Hawaii. Women living in neighborhoods with high density of on-premise alcohol outlets (Los Angeles County OR=1.15, 95% CI: 0.95,1.40) and (Hawaii OR=2.07, 95% CI: 1.43,3.01) had an increased odds of >2 drinks per day.
    Conclusion: This study suggests that neighborhood factors are associated with individual level behaviors and that there may be a need for multilevel interventions.
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2266450-6
    ISSN 1938-4114 ; 1934-2683 ; 1937-1888 ; 0096-882X
    ISSN (online) 1938-4114 ; 1934-2683
    ISSN 1937-1888 ; 0096-882X
    DOI 10.15288/jsad.23-00138
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Sociobiome - Individual and neighborhood socioeconomic status influence the gut microbiome in a multi-ethnic population in the US.

    Kwak, Soyoung / Usyk, Mykhaylo / Beggs, Dia / Choi, Heesun / Ahdoot, Dariush / Wu, Feng / Maceda, Lorraine / Li, Huilin / Im, Eun-Ok / Han, Hae-Ra / Lee, Eunjung / Wu, Anna H / Hayes, Richard B / Ahn, Jiyoung

    NPJ biofilms and microbiomes

    2024  Volume 10, Issue 1, Page(s) 19

    Abstract: Lower socioeconomic status (SES) is related to increased incidence and mortality due to chronic diseases in adults. Association between SES variables and gut microbiome variation has been observed in adults at the population level, suggesting that ... ...

    Abstract Lower socioeconomic status (SES) is related to increased incidence and mortality due to chronic diseases in adults. Association between SES variables and gut microbiome variation has been observed in adults at the population level, suggesting that biological mechanisms may underlie the SES associations; however, there is a need for larger studies that consider individual- and neighborhood-level measures of SES in racially diverse populations. In 825 participants from a multi-ethnic cohort, we investigated how SES shapes the gut microbiome. We determined the relationship of a range of individual- and neighborhood-level SES indicators with the gut microbiome. Individual education level and occupation were self-reported by questionnaire. Geocoding was applied to link participants' addresses with neighborhood census tract socioeconomic indicators, including average income and social deprivation in the census tract. Gut microbiome was measured using 16SV4 region rRNA gene sequencing of stool samples. We compared α-diversity, β-diversity, and taxonomic and functional pathway abundance by SES. Lower SES was significantly associated with greater α-diversity and compositional differences among groups, as measured by β-diversity. Several taxa related to low SES were identified, especially an increasing abundance of Prevotella copri and Catenibacterium sp000437715, and decreasing abundance of Dysosmobacter welbionis in terms of their high log-fold change differences. In addition, nativity and race/ethnicity have emerged as ecosocial factors that also influence the gut microbiota. Together, these results showed that lower SES was strongly associated with compositional and taxonomic measures of the gut microbiome, and may contribute to shaping the gut microbiota.
    MeSH term(s) Adult ; Humans ; Ethnicity ; Gastrointestinal Microbiome ; Social Class ; Socioeconomic Factors ; Income
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2817021-0
    ISSN 2055-5008 ; 2055-5008
    ISSN (online) 2055-5008
    ISSN 2055-5008
    DOI 10.1038/s41522-024-00491-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Exposure to outdoor ambient air toxics and risk of breast cancer: The multiethnic cohort.

    Heck, Julia E / He, Di / Wing, Sam E / Ritz, Beate / Carey, Chandra D / Yang, Juan / Stram, Daniel O / Le Marchand, Loïc / Park, Sungshim Lani / Cheng, Iona / Wu, Anna H

    International journal of hygiene and environmental health

    2024  Volume 259, Page(s) 114362

    Abstract: Background: A growing literature has reported associations between traffic-related air pollution and breast cancer, however there are fewer investigations into specific ambient agents and any putative risk of breast cancer development, particularly ... ...

    Abstract Background: A growing literature has reported associations between traffic-related air pollution and breast cancer, however there are fewer investigations into specific ambient agents and any putative risk of breast cancer development, particularly studies occurring in populations residing in higher pollution areas such as Los Angeles.
    Objectives: To estimate breast cancer risks related to ambient air toxics exposure at residential addresses.
    Methods: We examined the relationships between ambient air toxics and breast cancer risk in the Multiethnic Cohort among 48,665 California female participants followed for cancer from 2003 through 2013. We obtained exposure data on chemicals acting as endocrine disruptors or mammary gland carcinogens from the National-Scale Air Toxics Assessment. Cox proportional hazards models were used to estimate breast cancer risk per one interquartile range (IQR) increase in air toxics exposure lagged by 5-years. Stratified analyses were conducted by race, ethnicity, and hormone receptor types.
    Results: Among all women, increased risks of invasive breast cancer were observed with toxicants related to industries [1,1,2,2-tetrachloroethane (hazard ratio [HR] = 4.22, 95% confidence interval [95% CI] 3.18-5.60), ethylene dichloride (HR = 2.81, 95% CI 2.20-3.59), and vinyl chloride (HR = 2.27, 95% CI 1.81, 2.85); these 3 agents were correlated (r2 = 0.45-0.77)]. Agents related to gasoline production or combustion were related to increased breast cancer risk [benzene (HR = 1.32, 95% CI 1.24, 1.41), ethylbenzene (HR = 1.20, 95% CI 1.13-1.28), toluene (HR = 1.29, 95% CI 1.20-1.38), naphthalene (HR = 1.11, 95% CI 1.02-2.22), acrolein (HR = 2.26, 95% CI 1.92, 2.65)]. Higher hazard ratios were observed in African Americans and Whites compared to other racial and ethnic groups (p-heterogeneity <0.05 for traffic-related air toxics, acrolein, and vinyl acetate).
    Conclusions: Our findings suggest that specific toxic air pollutants may be associated with increase breast cancer risk.
    Language English
    Publishing date 2024-04-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2009176-X
    ISSN 1618-131X ; 1438-4639
    ISSN (online) 1618-131X
    ISSN 1438-4639
    DOI 10.1016/j.ijheh.2024.114362
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Variation in patterns of second primary malignancies across U.S. race and ethnicity groups: a Surveillance, Epidemiology, and End Results (SEER) analysis.

    McGuire, Valerie / Lichtensztajn, Daphne Y / Tao, Li / Yang, Juan / Clarke, Christina A / Wu, Anna H / Wilkens, Lynne / Glaser, Sally L / Park, Sungshim Lani / Cheng, Iona

    Cancer causes & control : CCC

    2024  Volume 35, Issue 5, Page(s) 799–815

    Abstract: Purpose: One in six incident cancers in the U.S. is a second primary cancer (SPC). Although primary cancers vary considerably by race and ethnicity, little is known about the population-based occurrence of SPC across these groups.: Methods: Using ... ...

    Abstract Purpose: One in six incident cancers in the U.S. is a second primary cancer (SPC). Although primary cancers vary considerably by race and ethnicity, little is known about the population-based occurrence of SPC across these groups.
    Methods: Using Surveillance, Epidemiology, and End Results (SEER) 12 data and relative to the general population, we calculated standardized incidence ratios (SIRs) and 95% confidence intervals (CIs) for SPC among 2,457,756 Hispanics, non-Hispanic Asian American/Pacific Islanders (NHAAPI), non-Hispanic black (NHB), and non-Hispanic whites (NHW) cancer survivors aged 45 years or older when diagnosed with a first primary cancer (FPC) from 1992 to 2015.
    Results: The risk of second primary bladder cancer after first primary prostate cancer was higher than expected in Hispanic (SIR = 1.18, 95% CI: 1.01-1.38) and NHAAPI (SIR = 1.41, 95% CI: 1.20-1.65) men than NHB and NHW men. Among women with a primary breast cancer, Hispanic, NHAAPI, and NHB women had a nearly 1.5-fold higher risk of a second primary breast cancer, while NHW women had a 6% lower risk. Among men with prostate cancer whose SPC was diagnosed 2 to <12 months, NHB men were at higher risk for colorectal cancer and Hispanic and NHW men for non-Hodgkin's lymphoma. In the same time frame for breast cancer survivors, Hispanic and NHAAPI women were significantly more likely than NHB and NHW women to be diagnosed with a second primary lung cancer.
    Conclusion: Future studies of SPC should investigate the role of shared etiologies, stage of diagnosis, treatment, and lifestyle factors after cancer survival across different racial and ethnic populations.
    MeSH term(s) Humans ; Male ; SEER Program ; Female ; Neoplasms, Second Primary/epidemiology ; Neoplasms, Second Primary/ethnology ; Middle Aged ; United States/epidemiology ; Aged ; Ethnicity/statistics & numerical data ; Incidence ; Cancer Survivors/statistics & numerical data ; Racial Groups/statistics & numerical data ; Aged, 80 and over ; Risk Factors
    Language English
    Publishing date 2024-01-11
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1064022-8
    ISSN 1573-7225 ; 0957-5243
    ISSN (online) 1573-7225
    ISSN 0957-5243
    DOI 10.1007/s10552-023-01836-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Racial and Ethnic Differences in the Population-Attributable Fractions of Alzheimer Disease and Related Dementias.

    Park, Song-Yi / Setiawan, Veronica Wendy / Crimmins, Eileen M / White, Lon R / Wu, Anna H / Cheng, Iona / Darst, Burcu F / Haiman, Christopher A / Wilkens, Lynne R / Le Marchand, Loїc / Lim, Unhee

    Neurology

    2024  Volume 102, Issue 3, Page(s) e208116

    Abstract: Background and objectives: Previous studies estimated that modifiable risk factors explain up to 40% of the dementia cases in the United States and that this population-attributable fraction (PAF) differs by race and ethnicity-estimates of future impact ...

    Abstract Background and objectives: Previous studies estimated that modifiable risk factors explain up to 40% of the dementia cases in the United States and that this population-attributable fraction (PAF) differs by race and ethnicity-estimates of future impact based on the risk factor prevalence in contemporary surveys. The aim of this study was to determine the race-specific and ethnicity-specific PAF of late-onset Alzheimer disease and related dementias (ADRDs) based on the risk factor prevalence and associations observed on the same individuals within a prospective cohort.
    Methods: Data were from Multiethnic Cohort Study participants (African American, Japanese American, Latino, Native Hawaiian, and White) enrolled in Medicare Fee-for-Service. We estimated the PAF based on the prevalence of risk factors at cohort baseline and their mutually adjusted association with subsequent ADRD incidence. Risk factors included low educational attainment and midlife exposures to low neighborhood socioeconomic status, unmarried status, history of hypertension, stroke, diabetes or heart disease, smoking, physical inactivity, short or long sleep duration, obesity, and low-quality diet, as well as
    Results: Among 91,881 participants (mean age 59.3 at baseline, 55.0% female participants), 16,507 incident ADRD cases were identified from Medicare claims (1999-2016, mean follow-up 9.3 years). The PAF for nongenetic factors combined was similar in men (24.0% [95% CI 21.3-26.6]) and women (22.8% [20.3-25.2]) but varied across Japanese American (14.2% [11.1-17.2]), White (21.9% [19.0-24.7]), African American (27.8% [22.3-33.0]), Native Hawaiian (29.3% [21.0-36.7]), and Latino (33.3% [27.5-38.5]) groups. The combined PAF was attenuated when accounting for competing risk of death, in both men (10.4%) and women (13.9%) and across racial and ethnic groups (4.7%-25.5%). The combined PAF was also different by age at diagnosis and ADRD subtypes, higher for younger (65-74 years: 43.2%) than older (75-84 years: 32.4%; ≥85 years: 11.3%) diagnoses and higher for vascular or unspecified ADRD than for AD or Lewy body dementia. An additional PAF of 11.8% (9.9-13.6) was associated with
    Discussion: Known risk factors explained about a third of the ADRD cases but with unequal distributions across racial and ethnic groups.
    MeSH term(s) Male ; Humans ; Female ; Aged ; United States/epidemiology ; Middle Aged ; Alzheimer Disease/epidemiology ; Cohort Studies ; Prospective Studies ; Apolipoprotein E4/genetics ; Medicare
    Chemical Substances Apolipoprotein E4
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000208116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Primary prevention of cancer is a global priority.

    Wu, Anna H

    Molecular nutrition & food research

    2011  Volume 55, Issue 6, Page(s) 817

    MeSH term(s) Animals ; Anticarcinogenic Agents/pharmacokinetics ; Anticarcinogenic Agents/pharmacology ; Anticarcinogenic Agents/therapeutic use ; Humans ; Life Style ; Neoplasms/prevention & control ; Tea/chemistry
    Chemical Substances Anticarcinogenic Agents ; Tea
    Language English
    Publishing date 2011-06
    Publishing country Germany
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 2160372-8
    ISSN 1613-4133 ; 1613-4125
    ISSN (online) 1613-4133
    ISSN 1613-4125
    DOI 10.1002/mnfr.201190023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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