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Article: Beneficial effects of the first case of washed microbiota transplantation for postorgasmic illness syndrome: a case report.

Quan, Yong-Xi / Lao, Ye-Dong / Wu, Hui-Yi / He, Xing-Xiang / Wu, Li-Hao

2024 Volume 12, Issue 2, Page(s) qfae015

Abstract: Introduction: Postorgasmic illness syndrome (POIS) is characterized by allergic symptoms and flu-like illness after ejaculation. There are still no effective treatments for POIS.: Aim: To report the first case of washed microbiota transplantation ( ... ...

Abstract	Introduction: Postorgasmic illness syndrome (POIS) is characterized by allergic symptoms and flu-like illness after ejaculation. There are still no effective treatments for POIS. Aim: To report the first case of washed microbiota transplantation (WMT) to treat patient with POIS. Methods: Data were collected from a patient with POIS who had received 3 courses of WMT: self-rating scale of POIS symptoms, Self-rating Anxiety Scale, Self-rating Depression Scale, and Symptom Checklist 90. The patient's stool samples for 16sDNA sequencing were collected 1 month after WMT. Results: POIS symptoms improved after WMT. Scores decreased from baseline after WMT: self-rating scale of POIS symptoms (before WMT, 16; after first, 16; after second, 8; after third, 9), Self-rating Anxiety Scale (45, 42.5, 37.5, 45), Self-rating Depression Scale (63.75, 58.75, 47.5, 50), and Symptom Checklist 90 (143, 140, 109, 149). Characteristics of the patient's gut microbiota changed. At the genus level, the relative abundance of beneficial bacteria increased, and some opportunistic pathogenic bacteria decreased. Conclusion: WMT may be an effective and safe choice for the treatment of patients with POIS by changing the gut microbiota of the host.
Language	English
Publishing date	2024-03-27
Publishing country	England
Document type	Case Reports
ZDB-ID	2734882-9
ISSN	2050-1161
ISSN	2050-1161
DOI	10.1093/sexmed/qfae015
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Exploring the Diagnostic and Prognostic Significance of Alkaline Phosphatase on Neutrophil Surface Membrane in Patients with Sepsis.

Hu, Ming / Sun, Runfeng / Huang, Tingting / Liu, Min / Wu, Huiyi / Wang, Jiaping

Alternative therapies in health and medicine

2024

Abstract: Background: Sepsis, characterized by life-threatening organ dysfunction, stems from an unregulated host response. Timely identification is pivotal for enhancing the prognosis of sepsis patients.: Objective: This study aims to explore the diagnostic ... ...

Abstract	Background: Sepsis, characterized by life-threatening organ dysfunction, stems from an unregulated host response. Timely identification is pivotal for enhancing the prognosis of sepsis patients. Objective: This study aims to explore the diagnostic and prognostic values of alkaline phosphatase on the surface membrane of neutrophils (mNAP) in peripheral blood among sepsis patients. Design: The study employed a retrospective design. Setting: This study was conducted at Donghai County People's Hospital. Participants: A total of 180 sepsis patients were selected and categorized into the sepsis shock group (n=45) and the sepsis non-shock group (n=135). Additionally, 35 patients with non-infectious systemic inflammatory response syndrome served as the control group. Interventions: mNAP was assessed via flow cytometry, while serum procalcitonin (PCT) and C-reactive protein (CRP) levels were measured through immunoassay. Primary outcome measures: (1) Changes in mNAP, PCT, and CRP. (2) Correlation of mNAP with CRP and PCT in sepsis patients. (3) Diagnostic values of mNAP, PCT, and CRP in sepsis. Results: Statistically significant differences in mNAP, PCT, and CRP were observed between the sepsis shock group, the sepsis non-shock group, and the control group (P = .000). The median value of mNAP (22627 Ab/c) in the 28-day death group was significantly higher than that (5100 Ab/c) in the survival group (P = .000). Spearman rank correlation analysis indicated a positive correlation between mNAP, PCT, and CRP in sepsis patients (P < .01). Conclusions: Both mNAP and PCT exhibit superior diagnostic specificity and sensitivity compared to CRP. While mNAP demonstrates similar sensitivity to PCT in diagnosing sepsis, its diagnostic specificity surpasses that of PCT. mNAP holds promise as a novel marker for the diagnosis and prognosis of sepsis.
Language	English
Publishing date	2024-04-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	1225073-9
ISSN	1078-6791
ISSN	1078-6791
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Article: Methylobacterium

Wu, Huiyi / Chen, Huanhao / Wu, Wenfeng / Zheng, Ping / Li, Yilei

International journal of clinical pharmacology and therapeutics

2023 Volume 62, Issue 2, Page(s) 96–100

Abstract: Clinical pharmacists participated in the drug therapy of peritonitis caused ... ...

Abstract	Clinical pharmacists participated in the drug therapy of peritonitis caused by
MeSH term(s)	Humans ; Anti-Bacterial Agents/therapeutic use ; Amikacin/therapeutic use ; Infections/complications ; Infections/drug therapy ; Renal Insufficiency/complications ; Peritonitis/diagnosis ; Peritonitis/drug therapy ; Peritonitis/etiology ; Pharmacy Service, Hospital ; Pharmacists
Chemical Substances	Anti-Bacterial Agents ; Amikacin (84319SGC3C)
Language	English
Publishing date	2023-11-23
Publishing country	Germany
Document type	Review ; Case Reports ; Journal Article
ZDB-ID	124384-6
ISSN	0946-1965 ; 0340-0026 ; 0300-9718 ; 0174-4879
ISSN	0946-1965 ; 0340-0026 ; 0300-9718 ; 0174-4879
DOI	10.5414/CP204483
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Article ; Online: Daytime napping, biological aging and cognitive function among middle-aged and older Chinese: insights from the China health and retirement longitudinal study.

Wu, Huiyi / Huang, Lei / Zhang, Shushan / Zhang, Yang / Lan, Yajia

Frontiers in public health

2023 Volume 11, Page(s) 1294948

Abstract: Objective: The complicated association of daytime napping, biological aging and cognitive function remains inconclusive. We aimed to evaluate the cross-sectional and longitudinal associations of daytime napping and two aging measures with cognition and ... ...

Abstract	Objective: The complicated association of daytime napping, biological aging and cognitive function remains inconclusive. We aimed to evaluate the cross-sectional and longitudinal associations of daytime napping and two aging measures with cognition and to examine whether napping affects cognition through a more advanced state of aging. Methods: Data was collected from the China Health and Retirement Longitudinal Study. Napping was self-reported. We calculated two published biological aging measures: Klemera and Doubal biological age (KDM-BA) and physiological dysregulation (PD), which derived information from clinical biomarkers. Cognitive z-scores were calculated at each wave. Linear mixed models were used to explore the longitudinal association between napping, two aging measures, and cognitive decline. Mediation analyses were performed to assess the mediating effects of biological age acceleration on the association between napping and cognition. Results: Participants aged over 45 years were included in the analyses. Non-nappers had greater KDM-BA and PD [LS means (LSM) = 0.255, Conclusion: In middle-aged and older Chinese, compared to moderate nappers, non-nappers seem to experience a more advanced state of aging and increased rates of cognitive decline. The aging status possibly mediates the association between napping and cognition. Moderate napping shows promise in promoting healthy aging and reducing the burden of cognitive decline in Chinese middle-aged and older adults.
MeSH term(s)	Aged ; Humans ; Middle Aged ; Aging ; Cognition/physiology ; Cross-Sectional Studies ; East Asian People ; Longitudinal Studies ; Retirement ; Sleep
Language	English
Publishing date	2023-11-17
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2711781-9
ISSN	2296-2565 ; 2296-2565
ISSN (online)	2296-2565
ISSN	2296-2565
DOI	10.3389/fpubh.2023.1294948
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Article ; Online: The Developmental Toxicity and Endocrine-Disrupting Effects of Fenpropathrin on

Wang, Lei / Jiang, Jinlin / Lu, Jianwei / Long, Tao / Guo, Yang / Dong, Shunan / Wu, Huiyi

Toxics

2023 Volume 11, Issue 12

Abstract: In the present study, the developmental toxicity and endocrine-disrupting effects of fenpropathrin ... ...

Abstract	In the present study, the developmental toxicity and endocrine-disrupting effects of fenpropathrin on
Language	English
Publishing date	2023-12-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2733883-6
ISSN	2305-6304 ; 2305-6304
ISSN (online)	2305-6304
ISSN	2305-6304
DOI	10.3390/toxics11121003
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Article ; Online: Is machine learning the future for atrial fibrillation screening?

Sivanandarajah, Pavidra / Wu, Huiyi / Bajaj, Nikesh / Khan, Sadia / Ng, Fu Siong

Cardiovascular digital health journal

2022 Volume 3, Issue 3, Page(s) 136–145

Abstract: Atrial fibrillation (AF) is the most common arrhythmia and causes significant morbidity and mortality. Early identification of AF may lead to early treatment of AF and may thus prevent AF-related strokes and complications. However, there is no current ... ...

Abstract	Atrial fibrillation (AF) is the most common arrhythmia and causes significant morbidity and mortality. Early identification of AF may lead to early treatment of AF and may thus prevent AF-related strokes and complications. However, there is no current formal, cost-effective strategy for population screening for AF. In this review, we give a brief overview of targeted screening for AF, AF risk score models used for screening and describe the different screening tools. We then go on to extensively discuss the potential applications of machine learning in AF screening.
Language	English
Publishing date	2022-05-16
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2666-6936
ISSN (online)	2666-6936
DOI	10.1016/j.cvdhj.2022.04.001
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Article: Transport and retention patterns of fragmental microplastics in saturated and unsaturated porous media: A real-time pore-scale visualization

Dong, Shunan / Zhou, Mengzhu / Su, Xiaoting / Xia, Jihong / Wang, Lei / Wu, Huiyi / Suakollie, Emmanuel B. / Wang, Dengjun

Water research. 2022 May 01, v. 214

2022

Abstract: The environmental behaviors of microplastics (MPs) have garnered ever-increasing attention globally. To overcome the limitations of commonly used “black box”, a real-time pore-scale visualization system including microscope, charge coupled device (CCD) ... ...

Abstract	The environmental behaviors of microplastics (MPs) have garnered ever-increasing attention globally. To overcome the limitations of commonly used “black box”, a real-time pore-scale visualization system including microscope, charge coupled device (CCD) microscope camera, and flow cell (connected with pump and sample collector) was used to unravel the transport and retention mechanisms of fragmental microplastics (FMPs) in saturated and unsaturated porous media. The breakthrough curves (BTCs) of effluent concentrations from the flow cells were used to quantitatively analyze FMPs transport. The videos gathered from different transport scenarios indicated that FMPs can move along with the bulk flow in porous media, but also move around the sand surfaces via sliding, rolling, and saltating patterns. The FMPs were retained in porous media mainly via deposition and straining in saturated porous media. Interestingly, little FMPs were captured by the air-water interface in unsaturated conditions. The mobility of FMPs varied with environmental factors, which became lower at higher solution ionic strength (IS), smaller grain size, and lower water content in porous media. Flow rate barely affected the transport of FMPs under 0.1 mM IS with the mass recovery rate ranging between 65.8 and 67.5%, but significantly enhanced FMPs mobility under 10 mM IS through reducing the moving rate. The IS and grain size showed a more significant effect on the transport of FMPs in unsaturated porous media. Our findings, for the first time, visually deciphered the transport and retention patterns of MPs with fragmental shapes on pore-scale, expanding our current knowledge of the fate and transport of more realistic MPs in the environment.
Keywords	cameras ; ionic strength ; liquid-air interface ; microplastics ; research ; sand ; water ; water content
Language	English
Dates of publication	2022-0501
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	202613-2
ISSN	1879-2448 ; 0043-1354
ISSN (online)	1879-2448
ISSN	0043-1354
DOI	10.1016/j.watres.2022.118195
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Application of Herbaceous Medications for Inflammatory Bowel Disease as a Complementary and Alternative Therapy.

Lin, Zili / Wu, Huiyi / Fu, Yiming / Dai, Shixue

Inflammatory bowel diseases

2019 Volume 25, Issue 12, Page(s) 1886–1895

Abstract: Background: Conventional medicine for the treatment of IBD is prevailingly composed of sulfadiazine, 5-aminosalicylic acid, glucocorticoid, and immunosuppressants, which have the merits of alleviating intestine inflammation, but long-term use of these ... ...

Abstract	Background: Conventional medicine for the treatment of IBD is prevailingly composed of sulfadiazine, 5-aminosalicylic acid, glucocorticoid, and immunosuppressants, which have the merits of alleviating intestine inflammation, but long-term use of these drugs may cause toxic side effects; additionally, these drugs may be expensive. In the pursuit of novel and more economic therapies, patients may increasingly look at complementary and alternative medicine (CAM). Recently, CAM is increasingly favored by the general public on account of its safety, low toxicity, and effectiveness. As a branch of CAM, herbal plants and their extracts have a significant effect on the treatment of IBD. Treatment of IBD with herbaceous plants has been reported, but specific mechanisms and effects have not yet been elaborated. Methods: English abstracts were identified in PubMed and Science Direct by multiple search terms, such as "herbal," "CAM," "IBD," "ulcerative colitis," "abdominal pain," and so on. Full-length articles were selected for review. Results: Herbaceous plants and their extracts have been shown to be effective against IBD in many studies, and herbaceous plants may be effective in treating symptoms such as abdominal pain, diarrhea, mucus, and bloody stools. Conclusions: Herbal medications could be used as a complementary and alternative treatment for IBD, but they require more rigorous scientific testing.
MeSH term(s)	Animals ; Complementary Therapies/methods ; Curcumin/therapeutic use ; Disease Models, Animal ; Herbal Medicine/trends ; Humans ; Inflammatory Bowel Diseases/therapy ; Plant Extracts/therapeutic use ; Randomized Controlled Trials as Topic
Chemical Substances	Plant Extracts ; Curcumin (IT942ZTH98)
Language	English
Publishing date	2019-11-07
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1340971-2
ISSN	1536-4844 ; 1078-0998
ISSN (online)	1536-4844
ISSN	1078-0998
DOI	10.1093/ibd/izz190
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Article: Comparison of the use of a spiral nasojejunal tube and transendoscopic enteral tubing in washed microbiota transplantation via the mid-gut route.

Zheng, Ya-Mei / Wu, Hui-Yi / Ye, Meng-Meng / Cai, Jie-Yi / Yuan, Yu / Xie, Wen-Rui / Xu, Jia-Ting / Liu, Tao / He, Xing-Xiang / Wu, Li-Hao

Heliyon

2024 Volume 10, Issue 9, Page(s) e30310

Abstract: Background: Methods for washed microbiota transplantation (WMT) through the mid-gut include transendoscopic enteral tubing (TET) and manual spiral nasojejunal tube (SNT) placement have not been studied.: Methods: This prospective interventional study ...

Abstract	Background: Methods for washed microbiota transplantation (WMT) through the mid-gut include transendoscopic enteral tubing (TET) and manual spiral nasojejunal tube (SNT) placement have not been studied. Methods: This prospective interventional study was performed at a single centre. Patients were divided into the SNT and mid-gut TET groups based on their conditions and wishes. In the SNT group, an SNT was passively inserted into the stomach, and abdominal X-rays were taken within 24 h to confirm tube placement in the small intestine. In the mid-gut TET group, mid-gut TET was placed in the small intestine for gastroscopy. Data on the clinical efficacy of WMT, intubation time, cost, overall comfort score, adverse reactions, etc., were collected from the two groups. Results: Sixty-three patients were included in the study (SNT group (n = 40) and mid-gut TET group (n = 23)). The clinical efficacy of WMT in the SNT and mid-gut TET groups was 90 % and 95.7 %, respectively (P = 0.644). Compared with the mid-gut TET group, the SNT group showed a shorter operation time (120 s vs. 258 s, P = 0.001) and a lower average cost (641.7 yuan vs. 1702.1 yuan, P = 0.001). There was no significant difference in the overall comfort score or the incidence of common discomfort symptoms between the two groups. Conclusion: The different implantation methods have different advantages; compared with mid-gut TET placement, manual SNT placement provides some benefits.
Language	English
Publishing date	2024-04-30
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e30310
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Article ; Online: Effects of pericapsular nerve group (PENG) block on postoperative recovery in elderly patients with hip fracture: study protocol for a randomised, parallel controlled, double-blind trial.

Luo, Wei / Liang, Jianhui / Wu, Jieting / Luo, Quehua / Wu, Huiyi / Ou, Yanhua / Li, Yuhui / Ma, WuHua

BMJ open

2022 Volume 12, Issue 3, Page(s) e051321

Abstract: Introduction: Hip fracture is a common and serious emergency in the elderly, and it is associated with severe pain, significant morbidity and mortality. The use of peripheral nerve block can relieve pain effectively and reduce opioid requirements, which ...

Abstract	Introduction: Hip fracture is a common and serious emergency in the elderly, and it is associated with severe pain, significant morbidity and mortality. The use of peripheral nerve block can relieve pain effectively and reduce opioid requirements, which may accelerate patient's recovery. The pericapsular nerve group (PENG) block has been found to provide an effective blockade to the hip joint with a potential motor-sparing effect, so we hypothesised that the PENG block may be an effective tool to enhance the recovery in elderly patients after hip fracture surgery. Methods and analysis: This study is a single-centred, randomised, parallel controlled, double-blind trial. A total of 92 elderly patients scheduled for hip fracture surgery will be divided into two groups at random to receive either ultrasound-guided femoral nerve block or ultrasound-guided PENG block. The primary outcome will be to compare the Quality of Recovery-15 scores at 24 hours postoperatively between the two groups. The secondary outcomes will include measuring and comparing the strength of the quadriceps, the visual analogue scale at rest and on movement, the total morphine consumption, the rescue analgesic, the first time of postoperative out-of-bed mobilisation and complications. Ethics and dissemination: This study was approved by the Institutional Review Board of the Ethics Committee of The First Affiliated Hospital of Guangzhou University of Chinese Medicine on 15 December 2020 (reference K2020-110). The results of this study will be published in peer-reviewed international journals. Trial registration number: ChiCTR2100042341.
MeSH term(s)	Aged ; Double-Blind Method ; Femoral Nerve ; Hip Fractures/complications ; Hip Fractures/surgery ; Humans ; Nerve Block/methods ; Pain Measurement ; Pain, Postoperative/drug therapy ; Pain, Postoperative/etiology ; Pain, Postoperative/prevention & control ; Randomized Controlled Trials as Topic
Language	English
Publishing date	2022-03-29
Publishing country	England
Document type	Clinical Trial Protocol ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2021-051321
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