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  1. Article ; Online: Stable and pure single-photons from greener quantum dots.

    Li, Yuxuan / Wu, Kaifeng

    Nature nanotechnology

    2023  Volume 18, Issue 9, Page(s) 968–969

    Language English
    Publishing date 2023-06-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2254964-X
    ISSN 1748-3395 ; 1748-3387
    ISSN (online) 1748-3395
    ISSN 1748-3387
    DOI 10.1038/s41565-023-01428-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Dielectric and Wavefunction Engineering of Electron Spin Lifetime in Colloidal Nanoplatelet Heterostructures.

    Li, Yulu / Wang, Lifeng / Xiang, Dongmei / Zhu, Jingyi / Wu, Kaifeng

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2024  Volume 11, Issue 12, Page(s) e2306518

    Abstract: Colloidal semiconductor nanoplatelets (NPLs) have emerged as low-cost and free-standing alternates of traditional quantum wells. The giant heavy- and light-hole splitting in NPLs allows for efficient optical spin injection. However, the electron spin ... ...

    Abstract Colloidal semiconductor nanoplatelets (NPLs) have emerged as low-cost and free-standing alternates of traditional quantum wells. The giant heavy- and light-hole splitting in NPLs allows for efficient optical spin injection. However, the electron spin lifetimes for prototypical CdSe NPLs are within a few picoseconds, likely limited by strong electron-hole exchange in these quantum- and dielectric-confined materials. Here how this hurdle can be overcome with engineered NPL-heterostructures is demonstrated. By constructing type-I CdSe/ZnS core/shell NPLs, dielectric screening inside the core is strongly enhanced, prolonging the electron spin polarization time (τ
    Language English
    Publishing date 2024-01-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202306518
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Induced Circularly Polarized Luminescence and Exciton Fine Structure Splitting in Magnetic-Doped Chiral Perovskites.

    Zhang, Zixuan / Liang, Wenfei / Xue, Jie / Li, Xin / Wu, Kaifeng / Lu, Haipeng

    ACS nano

    2024  

    Abstract: Magnetic impurity doping in semiconductors has emerged as an important strategy to endow exotic photophysical and magnetic properties. While most reported hosts are centrosymmetric semiconductors, doping magnetic ions into a noncentrosymmetric chiral ... ...

    Abstract Magnetic impurity doping in semiconductors has emerged as an important strategy to endow exotic photophysical and magnetic properties. While most reported hosts are centrosymmetric semiconductors, doping magnetic ions into a noncentrosymmetric chiral semiconductor can offer additional control of photonic and spin polarization. In this work, we synthesized a Mn
    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article
    ISSN 1936-086X
    ISSN (online) 1936-086X
    DOI 10.1021/acsnano.3c12851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Targeted inhibition of the PI3K/AKT/mTOR pathway by (+)-anthrabenzoxocinone induces cell cycle arrest, apoptosis, and autophagy in non-small cell lung cancer.

    Li, Xiao-Qian / Cheng, Xiao-Ju / Wu, Jie / Wu, Kai-Feng / Liu, Tie

    Cellular & molecular biology letters

    2024  Volume 29, Issue 1, Page(s) 58

    Abstract: Non-small cell lung cancer (NSCLC), characterized by low survival rates and a high recurrence rate, is a major cause of cancer-related mortality. Aberrant activation of the PI3K/AKT/mTOR signaling pathway is a common driver of NSCLC. Within this study, ... ...

    Abstract Non-small cell lung cancer (NSCLC), characterized by low survival rates and a high recurrence rate, is a major cause of cancer-related mortality. Aberrant activation of the PI3K/AKT/mTOR signaling pathway is a common driver of NSCLC. Within this study, the inhibitory activity of (+)-anthrabenzoxocinone ((+)-ABX), an oxygenated anthrabenzoxocinone compound derived from Streptomyces, against NSCLC is demonstrated for the first time both in vitro and in vivo. Mechanistically, it is confirmed that the PI3K/AKT/mTOR signaling pathway is targeted and suppressed by (+)-ABX, resulting in the induction of S and G2/M phase arrest, apoptosis, and autophagy in NSCLC cells. Additionally, the augmentation of intracellular ROS levels by (+)-ABX is revealed, further contributing to the inhibition of the signaling pathway and exerting inhibitory effects on tumor growth. The findings presented in this study suggest that (+)-ABX possesses the potential to serve as a lead compound for the treatment of NSCLC.
    MeSH term(s) Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/metabolism ; Carcinoma, Non-Small-Cell Lung/pathology ; TOR Serine-Threonine Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Humans ; Apoptosis/drug effects ; Autophagy/drug effects ; Lung Neoplasms/drug therapy ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Signal Transduction/drug effects ; Phosphatidylinositol 3-Kinases/metabolism ; Animals ; Cell Line, Tumor ; Cell Cycle Checkpoints/drug effects ; Mice, Nude ; Mice ; Cell Proliferation/drug effects ; Mice, Inbred BALB C ; Xenograft Model Antitumor Assays ; Reactive Oxygen Species/metabolism ; Antineoplastic Agents/pharmacology
    Chemical Substances TOR Serine-Threonine Kinases (EC 2.7.11.1) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; MTOR protein, human (EC 2.7.1.1) ; Reactive Oxygen Species ; Antineoplastic Agents
    Language English
    Publishing date 2024-04-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2108724-6
    ISSN 1689-1392 ; 1689-1392
    ISSN (online) 1689-1392
    ISSN 1689-1392
    DOI 10.1186/s11658-024-00578-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Charge Transfer from Quantum-Confined 0D, 1D, and 2D Nanocrystals.

    Li, Qiuyang / Wu, Kaifeng / Zhu, Haiming / Yang, Ye / He, Sheng / Lian, Tianquan

    Chemical reviews

    2024  Volume 124, Issue 9, Page(s) 5695–5763

    Abstract: The properties of colloidal quantum-confined semiconductor nanocrystals (NCs), including zero-dimensional (0D) quantum dots, 1D nanorods, 2D nanoplatelets, and their heterostructures, can be tuned through their size, dimensionality, and material ... ...

    Abstract The properties of colloidal quantum-confined semiconductor nanocrystals (NCs), including zero-dimensional (0D) quantum dots, 1D nanorods, 2D nanoplatelets, and their heterostructures, can be tuned through their size, dimensionality, and material composition. In their photovoltaic and photocatalytic applications, a key step is to generate spatially separated and long-lived electrons and holes by interfacial charge transfer. These charge transfer properties have been extensively studied recently, which is the subject of this Review. The Review starts with a summary of the electronic structure and optical properties of 0D-2D nanocrystals, followed by the advances in wave function engineering, a novel way to control the spatial distribution of electrons and holes, through their size, dimension, and composition. It discusses the dependence of NC charge transfer on various parameters and the development of the Auger-assisted charge transfer model. Recent advances in understanding multiple exciton generation, decay, and dissociation are also discussed, with an emphasis on multiple carrier transfer. Finally, the applications of nanocrystal-based systems for photocatalysis are reviewed, focusing on the photodriven charge separation and recombination processes that dictate the function and performance of these materials. The Review ends with a summary and outlook of key remaining challenges and promising future directions in the field.
    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 207949-5
    ISSN 1520-6890 ; 0009-2665
    ISSN (online) 1520-6890
    ISSN 0009-2665
    DOI 10.1021/acs.chemrev.3c00742
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  6. Article ; Online: Metformin induces ferroptosis through the Nrf2/HO-1 signaling in lung cancer.

    Deng, Chengmin / Xiong, Lin / Chen, Yang / Wu, Kaifeng / Wu, Jie

    BMC pulmonary medicine

    2023  Volume 23, Issue 1, Page(s) 360

    Abstract: Background: Metformin is the most frequently prescribed medication for the treatment of type II diabetes mellitus and has played an anti-tumor potential in a variety of cancer types. Metformin can inhibit the growth of many cancer cells through various ... ...

    Abstract Background: Metformin is the most frequently prescribed medication for the treatment of type II diabetes mellitus and has played an anti-tumor potential in a variety of cancer types. Metformin can inhibit the growth of many cancer cells through various mechanisms, including ferroptosis. However, it is still unclear whether metformin can induce ferroptosis in lung cancer.
    Methods: This study evaluated the anti-tumor effect of metformin by detecting the levels of oxidative stress factors, the levels of ferrous ions, and the expression of ferroptosis-related genes in A549 and H1299 lung cancer cell lines treated with or without metformin.
    Results: The results showed that metformin treatment increased the levels of MDA, ROS and iron ions, while decreased the levels of GSH, T-SOD and CAT. Meanwhile, metformin treatment reduced the protein expression levels of Gpx4 and SLC7A11, Nrf2 and HO-1, while the addition of ferroptosis inhibitor ferrostatin-1 reversed the reduction.
    Conclusions: These results demonstrated that metformin exerts anti-tumor effects by inducing ferroptosis through the Nrf2/HO-1 signaling pathway in lung cancer cells, providing a theoretical basis for drug therapy of lung cancer patients.
    MeSH term(s) Humans ; Ferroptosis ; Lung Neoplasms/drug therapy ; Metformin/pharmacology ; NF-E2-Related Factor 2 ; Signal Transduction ; Cell Line, Tumor
    Chemical Substances Metformin (9100L32L2N) ; NF-E2-Related Factor 2
    Language English
    Publishing date 2023-09-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 2059871-3
    ISSN 1471-2466 ; 1471-2466
    ISSN (online) 1471-2466
    ISSN 1471-2466
    DOI 10.1186/s12890-023-02655-6
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  7. Article ; Online: Sub-Single-Exciton Optical Gain in Lead Halide Perovskite Quantum Dots Revealed by Exciton Polarization Spectroscopy.

    Liu, Yuan / Li, Yuxuan / Gao, Kaimin / Zhu, Jingyi / Wu, Kaifeng

    Journal of the American Chemical Society

    2023  Volume 145, Issue 47, Page(s) 25864–25873

    Abstract: Optical gain of colloidal quantum dots (QDs) is often attained in the multiexciton regime, which strongly complicates their lasing applications as the gain lifetime is limited by nonradiative Auger recombination occurring typically on the picosecond time ...

    Abstract Optical gain of colloidal quantum dots (QDs) is often attained in the multiexciton regime, which strongly complicates their lasing applications as the gain lifetime is limited by nonradiative Auger recombination occurring typically on the picosecond time scale. In principle, low-threshold gain can be achieved if the gain-active emission has a sizable red shift compared to the absorption. But, this mechanism has been rarely observed in typical QDs featuring small Stokes shift due to their weak electron-phonon coupling. Here, we report the observation of sub-single-exciton gain in CsPbI
    Language English
    Publishing date 2023-11-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.3c10281
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  8. Article ; Online: Photophysics in emerging photovoltaics.

    Jackson, Nicholas E / Luther, Joseph M / Savoie, Brett M / Wu, Kaifeng

    The Journal of chemical physics

    2023  Volume 159, Issue 2

    Language English
    Publishing date 2023-07-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3113-6
    ISSN 1089-7690 ; 0021-9606
    ISSN (online) 1089-7690
    ISSN 0021-9606
    DOI 10.1063/5.0161842
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  9. Article ; Online: Entropy-Powered Endothermic Energy Transfer from CsPbBr

    He, Shan / Han, Yaoyao / Guo, Jingwei / Wu, Kaifeng

    The journal of physical chemistry letters

    2022  Volume 13, Issue 7, Page(s) 1713–1718

    Abstract: Colloidal semiconductor nanocrystals as triplet photosensitizers are characterized by a negligible intersystem crossing energy loss as compared to that of traditional molecular sensitizers. This property in principle allows for a large apparent anti- ... ...

    Abstract Colloidal semiconductor nanocrystals as triplet photosensitizers are characterized by a negligible intersystem crossing energy loss as compared to that of traditional molecular sensitizers. This property in principle allows for a large apparent anti-Stokes shift in sensitized triplet-triplet annihilation photon upconversion (TTA-UC) for a variety of applications. In previous systems, however, this advantage is largely erased by the energy loss associated with energy transfer from nanocrystals to surface-anchored triplet transmitter molecules. Here we report visible-to-ultraviolet TTA-UC from 473 to 355 nm, corresponding to an apparent anti-Stokes shift of 0.87 eV, with a quantum efficiency that reaches 4.5% (normalized at 100%). The system consists of CsPbBr
    Language English
    Publishing date 2022-02-14
    Publishing country United States
    Document type Journal Article
    ISSN 1948-7185
    ISSN (online) 1948-7185
    DOI 10.1021/acs.jpclett.2c00088
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  10. Article ; Online: Room-temperature coherent optical manipulation of hole spins in solution-grown perovskite quantum dots.

    Lin, Xuyang / Han, Yaoyao / Zhu, Jingyi / Wu, Kaifeng

    Nature nanotechnology

    2022  Volume 18, Issue 2, Page(s) 124–130

    Abstract: Manipulation of solid-state spin coherence is an important paradigm for quantum information processing. Current systems either operate at very low temperatures or are difficult to scale up. Developing low-cost, scalable materials whose spins can be ... ...

    Abstract Manipulation of solid-state spin coherence is an important paradigm for quantum information processing. Current systems either operate at very low temperatures or are difficult to scale up. Developing low-cost, scalable materials whose spins can be coherently manipulated at room temperature is thus highly attractive for a sustainable future of quantum information science. Here we report ambient-condition all-optical initialization, manipulation and readout of hole spins in an ensemble of solution-grown CsPbBr
    Language English
    Publishing date 2022-12-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2254964-X
    ISSN 1748-3395 ; 1748-3387
    ISSN (online) 1748-3395
    ISSN 1748-3387
    DOI 10.1038/s41565-022-01279-x
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