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  1. AU="Wu, Kui"
  2. AU="Lenden Hasse, Hélène"
  3. AU="Proffitt, Kamron S"
  4. AU="Liu, Jianxing"
  5. AU="Rubagotti, Enrico"
  6. AU="Patruno, A."
  7. AU="Amrutha Nisthul, A"
  8. AU="Fischer, K." AU="Fischer, K."
  9. AU="Pushap Raj"
  10. AU="Martin-Vila, Alicia"
  11. AU="Houska, Jiri"
  12. AU="Uwer, Lionel"
  13. AU="Yoo, Heejin"

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  1. Artikel ; Online: The effect of multiple factors on changes in organic-inorganic fractions of condensable particulate matter during coal combustion.

    Zou, Yue / Liu, Xiaowei / Wu, Kui / Zhou, Zijian / Xu, Minghou

    Chemosphere

    2024  Band 353, Seite(n) 141638

    Abstract: Condensable particulate matter (CPM) from coal combustion is the focus of current pollutant emission studies, and CPM can be divided into inorganic and organic fractions according to the component characteristics. At present, the effects of different ... ...

    Abstract Condensable particulate matter (CPM) from coal combustion is the focus of current pollutant emission studies, and CPM can be divided into inorganic and organic fractions according to the component characteristics. At present, the effects of different factors in the combustion process on the organic and inorganic components of CPM have not been discussed systematically. Here, we conducted combustion experiments collected the generated CPM on a well-controlled drip tube furnace, and investigated the effects of different factors on the generation of organic and inorganic components of CPM by varying the furnace wall insulation temperature, the ratio of gas supply components and the water vapor content in the flue gas. The results showed that the increase in combustion temperature (1300-1500 °C) and oxygen concentration (15-25%) reduced the total CPM generation by 9.8% and 19.98%, respectively, and the intervention of water vapor increased the ability of the whole CPM sampling device to capture ultrafine condensable particles. The generation of CPM organic components decreased with the enhancement of combustion temperature and oxygen content on combustion characteristics, and alkanes shifted to low carbon content. The amount of CPM inorganic components increased with the increase of water vapor content in the flue gas, and this change was dominated by SO
    Mesh-Begriff(e) Particulate Matter/analysis ; Air Pollutants/analysis ; Coal ; Steam ; Power Plants ; Oxygen
    Chemische Substanzen Particulate Matter ; Air Pollutants ; Coal ; Steam ; Oxygen (S88TT14065)
    Sprache Englisch
    Erscheinungsdatum 2024-03-03
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2024.141638
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Chemiluminescent probe for the detection of inverse electron demand Diels-Alder reaction between tetrazine and trans-Cyclooctene.

    Wu, Kui / Royzen, Maksim

    Bioorganic & medicinal chemistry

    2021  Band 47, Seite(n) 116400

    Abstract: A chemiluminescent probe has been developed, consisting of phenoxy-dioxetane moiety covalently attached to trans-cyclooctene. The inverse electron demand Diels-Alder reaction with tetrazine produces a cycloaddition product which undergoes a series of ... ...

    Abstract A chemiluminescent probe has been developed, consisting of phenoxy-dioxetane moiety covalently attached to trans-cyclooctene. The inverse electron demand Diels-Alder reaction with tetrazine produces a cycloaddition product which undergoes a series of spontaneous rearrangements resulting in emission of green light. The chemiluminescent probe can be applied to study bioconjugation chemistry with tetrazine-modified biomaterials, which have recently been shown to have great potential for anticancer drug delivery. This work describes in vitro studies, including NMR and spectroscopic investigation of chemiluminescence, which will pave way for future in vivo bioconjugation experiments.
    Mesh-Begriff(e) Aza Compounds/chemistry ; Benzene Derivatives/chemistry ; Cycloaddition Reaction ; Cyclooctanes/chemistry ; Heterocyclic Compounds, 1-Ring/chemical synthesis ; Heterocyclic Compounds, 1-Ring/chemistry ; Molecular Probes/chemical synthesis ; Molecular Probes/chemistry ; Molecular Structure
    Chemische Substanzen 1,2,4,5-tetrazine ; Aza Compounds ; Benzene Derivatives ; Cyclooctanes ; Heterocyclic Compounds, 1-Ring ; Molecular Probes ; 1,2-dioxetane (142GQA523X)
    Sprache Englisch
    Erscheinungsdatum 2021-09-08
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 1161284-8
    ISSN 1464-3391 ; 0968-0896
    ISSN (online) 1464-3391
    ISSN 0968-0896
    DOI 10.1016/j.bmc.2021.116400
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Prognostic value of left ventricular global longitudinal strain for major adverse cardiovascular events in patients with aortic valve disease:a meta-analysis.

    Liao, Hongsheng / Yang, Siyuan / Yu, Shaomei / Hu, Xuanyi / Meng, XiongWei / Wu, Kui

    Cardiology

    2024  

    Abstract: Introduction: Valvular heart disease is one of the most common heart diseases. It is characterized by abnormal function or structure of the heart valves. There may be no clinical symptoms in the early stages. Clinical symptoms of arrhythmia, heart ... ...

    Abstract Introduction: Valvular heart disease is one of the most common heart diseases. It is characterized by abnormal function or structure of the heart valves. There may be no clinical symptoms in the early stages. Clinical symptoms of arrhythmia, heart failure or thromboembolic events may occur in the late stages of the disease, such as palpitation after activities, breathing difficulties, fatigue and so on. Aortic valve disease is a major part of valvular heart disease. The main treatment for aortic valve disease is valve replacement or repair surgery, but it is extremely risky. Therefore, a rigorous prognostic assessment is extremely important for patients with aortic valve disease. The global longitudinal strain is an index that describes the deformation capacity of myocardium. There is evidence that it provides a test for systolic dysfunction other than LVEF (left ventricular ejection fraction) and provides additional prognostic information.
    Method: Search literature published between 2010 and 2023 on relevant platforms and contain the following keywords: "Aortic valve disease", "Aortic stenosis", "Aortic regurgitation" and "longitudinal strain" or "strain". The data is then extracted and collated for analysis.
    Results: A total of 15 articles were included. The total population involved in this study was 3678 individuals. The absolute value of LVGLS was higher in the no-MACE group than in the MACE group in patients with aortic stenosis (Z=8.10, P<0.00001), and impaired LVGLS was a risk factor for MACE in patients with aortic stenosis (HR=1.14, P<0.00001, 95% CI: 1.08-1.20). There was also a correlation between impaired LVGLS and aortic valve surgery in patients with aortic valve disease (HR=1.16, P<0.0001, 95% CI: 1.08-1.25) or patients with aortic valve regurgitation (HR=1.21, P=0.0004, 95% CI: 1.09-1.34). We also found that impaired LVGLS was no significant association between LVGLS and mortality during the period of follow-up in patient with aortic valve stenosis (HR =1.08, 95%CI: 0.94-1.25, p=0.28), but it was associated with mortality in studies of prospective analyses (HR =1.34, 95%CI:1.02-1.75, p=0.04).
    Conclusions: Impaired LVGLS correlates with major adverse cardiovascular events in patients with aortic valve disease, and it has predictive value for the prognosis of patients with aortic valve disease.
    Sprache Englisch
    Erscheinungsdatum 2024-02-01
    Erscheinungsland Switzerland
    Dokumenttyp Systematic Review
    ZDB-ID 80092-2
    ISSN 1421-9751 ; 0008-6312
    ISSN (online) 1421-9751
    ISSN 0008-6312
    DOI 10.1159/000536331
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: SLC38A2 promotes cell proliferation and invasion by promoting glutamine metabolism in adenomyosis.

    Wu, Kui / Gong, Wei / Hu, Jia-Chang / Duan, Ying-Chun / Ke, Hui-Hui / Chen, Li

    Experimental and therapeutic medicine

    2024  Band 27, Heft 5, Seite(n) 218

    Abstract: Adenomyosis is a benign uterine disorder that is associated with female infertility, a reduced clinical pregnancy rate and a high risk of miscarriage. Solute carrier family 38 member a2 (SLC38A2) is a glutamine (Gln) transporter that serves roles in ... ...

    Abstract Adenomyosis is a benign uterine disorder that is associated with female infertility, a reduced clinical pregnancy rate and a high risk of miscarriage. Solute carrier family 38 member a2 (SLC38A2) is a glutamine (Gln) transporter that serves roles in various medical conditions. The present study aimed to reveal the role of SLC38A2 in adenomyosis. The mRNA expression levels of SLC38A2 in eutopic endometrial (EU) and ectopic endometrial (EC) tissues from adenomyotic patients were examined by reverse transcription-quantitative PCR. EU and EC cell proliferation and invasion were analyzed by Cell Counting Kit-8 and Transwell assays. Changes in the oxygen consumption rate (OCR) were determined to indicate the mitochondrial respiratory function and observed using a Seahorse analyzer. SLC38A2 expression in EC tissues was upregulated compared with that in normal endometrial tissues. SLC38A2 knockdown repressed EC cell proliferation and invasion. In addition, the Gln content and OCR were decreased in EC cells transfected with SLC38A2-knockdown lentivirus, whereas SLC38A2 overexpression had the opposite effect in EU cells. Furthermore, the increased proliferation and invasion rates and Gln level induced by SLC38A2 overexpression in EU cells were alleviated by CB-839, a glutaminase inhibitor. SLC38A2 overexpression promoted Gln metabolism and oxygen consumption rate, resulting in an increase in cell proliferation and invasion in the adenomyosis context. The present study indicated that reduction of SLC38A2 expression could be a novel target for adenomyosis therapy, and SLC38A2 may be a valuable clinical diagnostic molecule for adenomyosis.
    Sprache Englisch
    Erscheinungsdatum 2024-03-21
    Erscheinungsland Greece
    Dokumenttyp Journal Article
    ZDB-ID 2683844-8
    ISSN 1792-1015 ; 1792-0981
    ISSN (online) 1792-1015
    ISSN 1792-0981
    DOI 10.3892/etm.2024.12506
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Influence of Cation-Size Effects of Alkaline Earth (Ae) Metals on Dimensionality and Optical Anisotropy Regulation in K

    Tian, Xinyu / Zhao, Ning / Wu, Kui / Xu, Jingjing / Lu, Dazhi / Yu, Haohai / Zhang, Huaijin

    Inorganic chemistry

    2024  Band 63, Heft 18, Seite(n) 8294–8301

    Abstract: Cationic substitution demonstrates significant potential for regulating structural dimensionality and physicochemical performance owing to the cation-size effect. Leveraging this characteristic, this study synthesized a new family of ... ...

    Abstract Cationic substitution demonstrates significant potential for regulating structural dimensionality and physicochemical performance owing to the cation-size effect. Leveraging this characteristic, this study synthesized a new family of K
    Sprache Englisch
    Erscheinungsdatum 2024-04-22
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.4c00608
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Case Report: Surgical management of idiopathic pulmonary aneurysms and review surgical approaches.

    Wu, Kui / Fan, Xuan / Hu, Xuanyi / Li, Xuejun / Yang, Siyuan

    Frontiers in cardiovascular medicine

    2023  Band 10, Seite(n) 1331982

    Abstract: Idiopathic pulmonary aneurysm is a clinically rare condition characterized by an unknown etiology and episodic occurrence. Despite its rarity, idiopathic pulmonary artery aneurysm poses potential risks to patients. Currently, there is a lack of ... ...

    Abstract Idiopathic pulmonary aneurysm is a clinically rare condition characterized by an unknown etiology and episodic occurrence. Despite its rarity, idiopathic pulmonary artery aneurysm poses potential risks to patients. Currently, there is a lack of established clinical guidelines and consensus regarding its management, leading to ongoing controversies in treatment strategies. Particularly, the optimal approach for addressing the main pulmonary artery, its branches, and the pulmonary artery valve remains uncertain. A 57-year-old female patient presented with chest pain and tightness, leading to the diagnosis of idiopathic pulmonary artery aneurysm after excluding other potential causes. Subsequently, she underwent surgical treatment. However, during the surgery, the pulmonary artery wall was found to be extremely weak, prompting us to employ a surgical approach involving the utilization of autologous vessel wrapping with artificial grafts. By summarizing almost all surgical treatment strategies reported in recent years, including the management of pulmonary artery vessels and the pulmonary valve, we have developed a treatment flow chart. This flowchart serves as a valuable guide for the management of future cases presenting similar challenges, offering clinicians valuable insights and evidence-based recommendations.
    Sprache Englisch
    Erscheinungsdatum 2023-12-20
    Erscheinungsland Switzerland
    Dokumenttyp Case Reports
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2023.1331982
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Neoadjuvant immunotherapy for resectable esophagal squamous cell carcinoma: An ace up the sleeve.

    Zhou, Qing / Yuan, Jingnan / Wu, Kui / Yin, Jun / Tan, Lijie

    Clinical and translational medicine

    2023  Band 13, Heft 9, Seite(n) e1426

    Mesh-Begriff(e) Humans ; Neoadjuvant Therapy ; Carcinoma, Squamous Cell/drug therapy
    Sprache Englisch
    Erscheinungsdatum 2023-08-10
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2697013-2
    ISSN 2001-1326 ; 2001-1326
    ISSN (online) 2001-1326
    ISSN 2001-1326
    DOI 10.1002/ctm2.1426
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Crystallization Thermodynamics of α-Lactose Monohydrate in Different Solvents.

    Guan, Youliang / Yang, Zujin / Wu, Kui / Ji, Hongbing

    Pharmaceutics

    2022  Band 14, Heft 9

    Abstract: It is common to find that some of the lactose in dairy powders and pharmaceutical tablets is present in the unstable amorphous state. Therefore, their crystallization thermodynamics in different solvents are particularly important. In this paper, the ... ...

    Abstract It is common to find that some of the lactose in dairy powders and pharmaceutical tablets is present in the unstable amorphous state. Therefore, their crystallization thermodynamics in different solvents are particularly important. In this paper, the solubility of α-lactose monohydrate (α-LM) in 15 mono-solvents such as ethanol, isopropanol, methanol, 1-propanol, 1-butanol, 2-butanol, isobutanol, 1-pentanol, isoamylol, 1-hexanol, 1-heptanol, 1-octanol, propanoic acid, acetonitrile, and cyclohexanone was evaluated by using the gravimetric method in the temperature ranges from 274.05 K to 323.05 K at constant pressure (1 atm). In the given temperature range, the solubility of α-LM in these solvents increased with the rising of temperature, the highest solubility of α-LM was found in methanol (2.37 × 104), and the lowest was found in 1-hexanol (0.80 × 105). In addition, the increase of α-LM solubility in isopropanol was the largest. The sequence at 298.15 K was: methanol > 1-butanol > isopropanol > ethanol > 1-propanol > 1-heptanol > isobutanol > propionic acid > 1-pentanol > 1-octanol > acetonitrile > isoamylol > 2-butanol > cyclohexanone > 1-hexanol. Solvent effect analysis shows that the properties of α-LM are more important than those of solvents. The Apelblat equation, λh equation, Wilson model, and NRTL model were used to correlate the experimental values. The root-mean-square deviation (RMSD) and relative average deviation (RAD) of all models were less than 2.68 × 10−2 and 1.41 × 10−6, respectively, implying that the fitted values of four thermodynamic models all agreed well with the experimental values. Moreover, the thermodynamic properties of the dissolution process (i.e., dissolution Gibbs free energy (ΔdisG), molar enthalpy (ΔdisH), and molar entropy (ΔdisS)) for α-LM in selected solvents were determined. The results indicate that ΔdisH/(J/mol) (from 0.2551 to 6.0575) and ΔdisS/(J/mol/K) (from 0.0010 to 0.0207) of α-LM in these solvents are all positive, and the values of ΔdisH and ΔdisS. ΔdisG/(J/mol) (from −0.0184 to −0.6380) are all negative. The values were observed to decrease with rising temperatures, implying that α-LM dissolution is an endothermic, entropy-driven, and spontaneous process. The solid−liquid equilibrium data and dissolution thermodynamics of α-LM were obtained, which provide a basis for industrial production.
    Sprache Englisch
    Erscheinungsdatum 2022-08-25
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics14091774
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Facile Preparation of Loose P84 Copolyimide/GO Composite Membrane with Excellent Selectivity and Solvent Resistance.

    Han, Runlin / Wu, Kui / Xu, Lingfeng

    Polymers

    2022  Band 14, Heft 7

    Abstract: In this study, multilayer graphene oxide (GO) was used to prepare the functional layer of polyimide/GO composite membrane with polyimide (P84) used as the supporting layer. Chitosan added in the functional layer was utilized to adjust the selectivity of ... ...

    Abstract In this study, multilayer graphene oxide (GO) was used to prepare the functional layer of polyimide/GO composite membrane with polyimide (P84) used as the supporting layer. Chitosan added in the functional layer was utilized to adjust the selectivity of the composite membrane. The effects of GO and chitosan contents on membrane morphology and separation performance were investigated in detail. The composite membrane showed high rejection to Congo red and Methyl orange with high flux but low rejection to Na
    Sprache Englisch
    Erscheinungsdatum 2022-03-27
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym14071353
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Buch ; Online: Second-Order Convergent Collision-Constrained Optimization-Based Planner

    Liang, Chen / Gao, Xifeng / Wu, Kui / Pan, Zherong

    2023  

    Abstract: Finding robot poses and trajectories represents a foundational aspect of robot motion planning. Despite decades of research, efficiently and robustly addressing these challenges is still difficult. Existing approaches are often plagued by various ... ...

    Abstract Finding robot poses and trajectories represents a foundational aspect of robot motion planning. Despite decades of research, efficiently and robustly addressing these challenges is still difficult. Existing approaches are often plagued by various limitations, such as intricate geometric approximations, violations of collision constraints, or slow first-order convergence. In this paper, we introduce two novel optimization formulations that offer provable robustness, achieving second-order convergence while requiring only a convex approximation of the robot's links and obstacles. Our first method, known as the Explicit Collision Barrier (ECB) method, employs a barrier function to guarantee separation between convex objects. ECB uses an efficient matrix factorization technique, enabling a second-order Newton's method with an iterative complexity linear in the number of separating planes. Our second method, referred to as the Implicit Collision Barrier (ICB) method, further transforms the separating planes into implicit functions of robot poses. We show such an implicit objective function is twice-differentiable, with derivatives evaluated at a linear complexity. To assess the effectiveness of our approaches, we conduct a comparative study with a first-order baseline algorithm across six testing scenarios. Our results unequivocally justify that our method exhibits significantly faster convergence rates compared to the baseline algorithm.
    Schlagwörter Computer Science - Robotics
    Thema/Rubrik (Code) 518
    Erscheinungsdatum 2023-11-03
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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