Book ; Online ; E-Book: Nonclassical ion channels in the nervous system
(Methods in signal transduction series)
2021
Abstract: Intro -- Half Title -- Series Page -- Title Page -- Copyright Page -- Contents -- Preface -- Editors -- Contributors -- 1. Endogenous Activation and Neurophysiological Functions of Acid-Sensing Ion Channels -- 1.1 Introduction -- 1.2 Endogenous ... ...
| Author's details | edited by Tian-le Xu and Long-Jun Wu |
|---|---|
| Series title | Methods in signal transduction series |
| Abstract | Intro -- Half Title -- Series Page -- Title Page -- Copyright Page -- Contents -- Preface -- Editors -- Contributors -- 1. Endogenous Activation and Neurophysiological Functions of Acid-Sensing Ion Channels -- 1.1 Introduction -- 1.2 Endogenous Conditions That May Activate ASICs -- 1.2.1 Metabolic Production of Protons -- 1.2.1.1 Carbon Dioxide -- 1.2.1.2 Lactate -- 1.2.2 Acidification Niche and Proton Generators -- 1.2.2.1 Na+/H+ Exchangers (NHEs) -- 1.2.2.2 Hydrogen Voltage-Gated Channel 1 (Hv1) -- 1.2.2.3 Carbonic Anhydrases (CAs) -- 1.3 ASICs and Neurophysiological Functions -- 1.3.1 Synaptic Development -- 1.3.2 Synaptic Plasticity -- 1.3.3 Regional Specific Functions of ASICs -- 1.3.3.1 Amygdala -- 1.3.3.2 Retina -- 1.3.3.3 Dorsal Root Ganglia (DRG) -- 1.4 Summary and Outlook -- Acknowledgements -- References -- 2. Acid-Sensing Ion Channels and Synaptic Plasticity: A Revisit -- 2.1 Introduction -- 2.2 Protons and ASICs in Synaptic Transmission -- 2.2.1 Protons Act as a Neurotransmitter in Synaptic Signaling -- 2.2.2 Modulation of Synaptic Transmission by ASICs -- 2.3 ASIC1a in Synaptic Plasticity -- 2.3.1 ASIC1a in LTP -- 2.3.1.1 Hippocampus -- 2.3.1.2 Amygdala -- 2.3.1.3 ACC -- 2.3.2 ASIC1a in LTD -- 2.3.2.1 Hippocampus -- 2.3.2.2 Insular Cortex -- 2.4 ASICs in Synaptic Remodeling -- 2.5 Summary and Future Perspectives -- Acknowledgements -- References -- 3. Trimeric Scaffold Ligand-Gated Ion Channels -- 3.1 An Introduction of Trimeric Scaffold of Ligand-Gated Ion Channels (TS-LGICs) -- 3.2 Subunit Stoichiometry and Single Subunit Architecture of P2X Receptors and ASIC Channels -- 3.3 Ion Permeation Pathway of P2X Receptors and ASIC Channels -- 3.4 Ligand Recognitions of P2X Receptors and ASIC Channels -- 3.5 Coordinated Allostery During Channel Activation of P2X Receptors and ASIC Channels. |
| Keywords | Electronic books |
| Language | English |
| Size | 1 Online-Ressource (xiv, 413 Seiten), Illustrationen |
| Publisher | CRC Press |
| Publishing place | Boca Raton |
| Publishing country | United States |
| Document type | Book ; Online ; E-Book |
| Remark | Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer |
| HBZ-ID | HT021025880 |
| ISBN | 978-1-00-040374-9 ; 9780367623951 ; 9781003109266 ; 1-00-040374-2 ; 0367623951 ; 1003109268 |
| Database | ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture |
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