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Article: [Meta-analysis of β-blockers for the primary prevention of liver cirrhosis with clinically significant portal hypertension with no or small esophageal varices].

Su, X / Li, W J / Chen, Z / Wu, Q B / Yin, M H / Han, X / Zhang, D P / Zhou, X Q / Zhu, H

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

2023 Volume 30, Issue 11, Page(s) 1237–1245

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Humans ; Esophageal and Gastric Varices/complications ; Esophageal and Gastric Varices/drug therapy ; Adrenergic beta-Antagonists/adverse effects ; Hypertension, Portal/complications ; Hypertension, Portal/drug therapy ; Liver Cirrhosis/complications ; Liver Cirrhosis/drug therapy ; Gastrointestinal Hemorrhage/prevention & control ; Gastrointestinal Hemorrhage/etiology ; Primary Prevention
Chemical Substances	Adrenergic beta-Antagonists
Language	Chinese
Publishing date	2023-02-27
Publishing country	China
Document type	Meta-Analysis ; English Abstract ; Journal Article
ISSN	1007-3418
ISSN	1007-3418
DOI	10.3760/cma.j.cn501113-20210330-00150
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Article ; Online: Clinicopathological characteristics and prognosis of schistosomal colorectal cancer.

Wang, M / Wu, Q B / He, W B / Wang, Z Q

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2016 Volume 18, Issue 10, Page(s) 1005–1009

Abstract: Aim: The aim of the present study was to investigate the clinicopathological characteristics and prognostic factors of schistosomal colorectal cancer.: Method: A total of 74 consecutive schistosomal colorectal cancer patients who underwent curative ... ...

Abstract	Aim: The aim of the present study was to investigate the clinicopathological characteristics and prognostic factors of schistosomal colorectal cancer. Method: A total of 74 consecutive schistosomal colorectal cancer patients who underwent curative surgery from July 2009 to July 2012 were included in this study. The clinical and pathological characteristics of all 74 patients were analysed and univariate and multivariate analyses were performed. This study demonstrated positive correlations between the site of deposition of schistosomal eggs and certain essential variables. Results: Depositional site of schistosome eggs, carcinoembryonic antigen (CEA) level and the pathological N and T stages were statistically significantly correlated with overall survival (OS). The pathological T stage and the CEA level were independent prognostic factors for OS. The site of deposition of schistosome eggs was positively correlated with the T and N stages, tumour size, the CEA level and the resection margins. Conclusions: Schistosome eggs might be associated with tumorigenesis. The site of deposition of schistosome eggs was statistically significantly correlated with OS but it was not an independent prognostic factor for OS. It was, however, correlated with the depth of the tumour. The presence of schistosoma eggs at the margin did not affect the patient's prognosis or anastomotic healing. The existing standard surgical approach was equally applicable to schistosomal colorectal cancer. It was not necessary to expand the scope of surgical resection.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Animals ; Carcinoembryonic Antigen/blood ; Colectomy ; Colon/parasitology ; Colorectal Neoplasms/blood ; Colorectal Neoplasms/parasitology ; Colorectal Neoplasms/surgery ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Neoplasm Staging ; Prognosis ; Rectum/parasitology ; Schistosoma ; Survival Rate ; Tumor Burden
Chemical Substances	Carcinoembryonic Antigen
Language	English
Publishing date	2016-10
Publishing country	England
Document type	Journal Article
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.13317
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Article: [Development and validation of a prognostic prediction model for patients with stage Ⅰ to Ⅲ colon cancer incorporating high-risk pathological features].

Li, K X / Wu, Q B / Zhao, F Q / Zhang, J L / Luo, S L / Hu, S D / Wu, B / Li, H L / Lin, G L / Qiu, H Z / Lu, J Y / Xu, L / Wang, Z / Du, X H / Kang, L / Wang, X / Wang, Z Q / Liu, Q / Xiao, Y

Zhonghua wai ke za zhi [Chinese journal of surgery

2023 Volume 61, Issue 9, Page(s) 753–759

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Male ; Female ; Humans ; Prognosis ; Neoplasm Staging ; Retrospective Studies ; Nomograms ; Lymph Nodes/pathology ; Risk Factors ; Colonic Neoplasms/surgery
Language	Chinese
Publishing date	2023-07-25
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	604573-x
ISSN	0529-5815
ISSN	0529-5815
DOI	10.3760/cma.j.cn112139-20230403-00137
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Article ; Online: Effects of melatonin on spinal cord injury-induced oxidative damage in mice testis.

Yuan, X-C / Wang, P / Li, H-W / Wu, Q-B / Zhang, X-Y / Li, B-W / Xiu, R-J

Andrologia

2017 Volume 49, Issue 7

Abstract: This study evaluated the effects of melatonin on spinal cord injury (SCI)-induced oxidative damage in testes. Adult male C57BL/6 mice were randomly divided into sham-, SCI- or melatonin (10 mg/kg, i.p.)-treated SCI groups. To induce SCI, a standard ... ...

Abstract	This study evaluated the effects of melatonin on spinal cord injury (SCI)-induced oxidative damage in testes. Adult male C57BL/6 mice were randomly divided into sham-, SCI- or melatonin (10 mg/kg, i.p.)-treated SCI groups. To induce SCI, a standard weight-drop method that induced a contusion injury at T10 was used. After 1 week, testicular blood flow velocity was measured using the Laser Doppler Line Scanner. Malondialdehyde (MDA), glutathione (GSH), oxidised glutathione (GSSG) and myeloperoxidase (MPO) were measured in testis homogenates. Microvascular permeability of the testes to Evan's Blue was examined by spectrophotometric and fluorescence microscopic quantitation. The tight junction protein zonula occludens-1 (ZO-1) and occludin in testes were assessed by immunoblot analysis. Melatonin increased the reduced blood flow and decreased SCI-induced permeability of capillaries. MDA levels and MPO activity were elevated in the SCI group compared with shams, which was reversed by melatonin. In contrast, SCI-induced reductions in GSH/GSSG ratio were restored by melatonin. Decreased expression of ZO-1 and occludin was observed, which was attenuated by melatonin. Overall, melatonin treatment protects the testes against oxidative stress damage caused by SCI.
Language	English
Publishing date	2017-09
Publishing country	Germany
Document type	Journal Article
ZDB-ID	7280-1
ISSN	1439-0272 ; 0303-4569
ISSN (online)	1439-0272
ISSN	0303-4569
DOI	10.1111/and.12692
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Zs.A 665: Show issues

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Article ; Online: Identification of smut-responsive genes in sugarcane using cDNA-SRAP.

Huang, N / Zhang, Y Y / Xiao, X H / Huang, L / Wu, Q B / Que, Y X / Xu, L P

Genetics and molecular research : GMR

2015 Volume 14, Issue 2, Page(s) 6808–6818

Abstract: Sugarcane smut, caused by the fungus Sporisorium scitamineum, is one of the main diseases that affect sugarcane worldwide. In the present study, the cDNA-SRAP technique was used to identify genes that are likely to be involved in the response of ... ...

Abstract	Sugarcane smut, caused by the fungus Sporisorium scitamineum, is one of the main diseases that affect sugarcane worldwide. In the present study, the cDNA-SRAP technique was used to identify genes that are likely to be involved in the response of sugarcane to S. scitamineum infection. In total, 21 bands with significant differential expression during cDNA-SRAP analysis were cloned and sequenced. Real-time qPCR confirmation demonstrated that expression of 19 of these 21 differential bands was consistent with the expression observed during cDNA-SRAP analysis, with a deduced false positive rate of 9.5%. Sequence alignment indicated that 18 of 19 differentially expressed genes showed homologies from 19% to 100% to certain genes in GenBank, including the following genes: topoisomerase (EU048780), ethylene insensitive (EU048778), and tetraspanin (EU048770). A real-time qPCR assay showed that during 0-72 h after pathogen infection, expression of the topoisomerase and the ethylene insensitive genes was upregulated, whereas expression of the tetraspanin gene was downregulated, identical to the expression patterns observed under salicylic acid treatment. Therefore, all three genes are thought to play a role during S. scitamineum challenge, but with different functions. To our knowledge, this is the first report on the application of cDNA-SRAP in differential gene expression analysis of sugarcane during a sugarcane-S. scitamineum interaction. The results obtained also contribute to a better understanding of the molecular mechanisms associated with sugarcane-S. scitamineum interactions.
MeSH term(s)	Base Sequence ; Cloning, Molecular ; DNA Topoisomerases/genetics ; DNA Topoisomerases/immunology ; DNA Topoisomerases/metabolism ; DNA, Complementary/genetics ; DNA, Complementary/metabolism ; Gene Expression Profiling ; Gene Expression Regulation, Plant ; Host-Pathogen Interactions ; Molecular Sequence Data ; Plant Diseases/genetics ; Plant Diseases/immunology ; Plant Diseases/microbiology ; Plant Immunity/genetics ; Plant Proteins/genetics ; Plant Proteins/immunology ; Plant Proteins/metabolism ; Real-Time Polymerase Chain Reaction/methods ; Saccharum/genetics ; Saccharum/immunology ; Saccharum/metabolism ; Saccharum/microbiology ; Sequence Alignment ; Sequence Analysis, DNA ; Signal Transduction ; Stress, Physiological ; Tetraspanins/genetics ; Tetraspanins/immunology ; Tetraspanins/metabolism ; Ustilaginales/growth & development ; Ustilaginales/pathogenicity
Chemical Substances	DNA, Complementary ; Plant Proteins ; Tetraspanins ; DNA Topoisomerases (EC 5.99.1.-)
Language	English
Publishing date	2015-06-18
Publishing country	Brazil
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2114039-X
ISSN	1676-5680 ; 1676-5680
ISSN (online)	1676-5680
ISSN	1676-5680
DOI	10.4238/2015.June.18.23
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Article ; Online: Effect of electrochemical structuring of Ti6Al4V on osteoblast behaviour in vitro.

Birch, M A / Johnson-Lynn, S / Nouraei, S / Wu, Q-B / Ngalim, S / Lu, W-J / Watchorn, C / Yang, T-Y / McCaskie, A W / Roy, S

Biomedical materials (Bristol, England)

2012 Volume 7, Issue 3, Page(s) 35016

Abstract: Topography and surface chemistry have a profound effect on the way in which cells interact with an implant, which in turn impacts on clinical use and performance. In this paper we examine an electrochemical polishing approach in H2SO4/methanol that can ... ...

Abstract	Topography and surface chemistry have a profound effect on the way in which cells interact with an implant, which in turn impacts on clinical use and performance. In this paper we examine an electrochemical polishing approach in H2SO4/methanol that can be applied to the widely used orthopaedic/dentistry implant material, Ti6Al4V, to produce structured surfaces. The surface roughness, as characterized by R(a), was found to be dependent on the time of electropolishing but not on the voltage parameters used here. The surface chemistry, however, was dependent on the applied electrochemical potential. It was found that the chemical composition of the surface layer was modified during the electrochemical process, and at high potentials (9.0 V) a pure TiO2 layer of at least 10 nm was created on top of the bulk alloy. Characterization of these surfaces with rat cells from the osteoblast lineage provided further evidence of contact guidance by microscale topography with morphology analysis correlating with surface roughness (R(a) 300–550 nm). Formation of a bone-like matrix after long-term culture on these surfaces was not strongly dependent upon R(a) values but followed the voltage parameter. These findings suggest that the surfaces created by treatment at higher voltages (9.0 V) produced a nanoscale layer of pure TiO2 on the Ti6Al4V surface that influenced the programme of cellular differentiation culminating in osteogenesis.
MeSH term(s)	Animals ; Biocompatible Materials/chemistry ; Cell Survival ; Cells, Cultured ; Electroplating ; Materials Testing ; Osteoblasts/cytology ; Osteoblasts/physiology ; Rats ; Surface Properties ; Titanium/chemistry
Chemical Substances	Biocompatible Materials ; titanium alloy (TiAl6V4) (12743-70-3) ; titanium dioxide (15FIX9V2JP) ; Titanium (D1JT611TNE)
Language	English
Publishing date	2012-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2265222-X
ISSN	1748-605X ; 1748-6041
ISSN (online)	1748-605X
ISSN	1748-6041
DOI	10.1088/1748-6041/7/3/035016
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Book ; Online: Electronics of Time-of-flight Measurement for Back-n at CSNS

Yu, T. / Cao, P. / Ji, X. Y. / Xie, L. K. / Huang, X. R. / An, Q. / Bai, H. Y. / Bao, J. / Chen, Y. H. / Cheng, P. J. / Cui, Z. Q. / Fan, R. R. / Feng, C. Q. / Gu, M. H. / Han, Z. J. / He, G. Z. / He, Y. C. / He, Y. F. / Huang, H. X. /

Huang, W. L. / Ji, X. L. / Jiang, H. Y. / Jiang, W. / Jing, H. Y. / Kang, L. / Li, B. / Li, L. / Li, Q. / Li, X. / Li, Y. / Liu, R. / Liu, S. B. / Liu, X. Y. / Luan, G. Y. / Ma, Y. L. / Ning, C. J. / Ren, J. / Ruan, X. C. / Song, Z. H. / Sun, H. / Sun, X. Y. / Sun, Z. J. / Tan, Z. X. / Tang, J. Y. / Tang, H. Q. / Wang, P. C. / Wang, Q. / Wang, T. F. / Wang, Y. F. / Wang, Z. H. / Wang, Z. / Wen, J. / Wen, Z. W. / Wu, Q. B. / Wu, X. G. / Wu, X. / Yang, Y. W. / Yi, H. / Yu, L. / Yu, Y. J. / Zhang, G. H. / Zhang, L. Y. / Zhang, J. / Zhang, Q. M. / Zhang, Q. W. / Zhang, X. P. / Zhao, Y. T. / Zhong, Q. P. / Zhou, L. / Zhou, Z. Y. / Zhu, K. J.

2018

Abstract: Back-n is a white neutron experimental facility at China Spallation Neutron Source (CSNS). The time structure of the primary proton beam make it fully applicable to use TOF (time-of-flight) method for neutron energy measuring. We implement the ... ...

Abstract	Back-n is a white neutron experimental facility at China Spallation Neutron Source (CSNS). The time structure of the primary proton beam make it fully applicable to use TOF (time-of-flight) method for neutron energy measuring. We implement the electronics of TOF measurement on the general-purpose readout electronics designed for all of the seven detectors in Back-n. The electronics is based on PXIe (Peripheral Component Interconnect Express eXtensions for Instrumentation) platform, which is composed of FDM (Field Digitizer Modules), TCM (Trigger and Clock Module), and SCM (Signal Conditioning Module). T0 signal synchronous to the CSNS accelerator represents the neutron emission from the target. It is the start of time stamp. The trigger and clock module (TCM) receives, synchronizes and distributes the T0 signal to each FDM based on the PXIe backplane bus. Meantime, detector signals after being conditioned are fed into FDMs for waveform digitizing. First sample point of the signal is the stop of time stamp. According to the start, stop time stamp and the time of signal over threshold, the total TOF can be obtained. FPGA-based (Field Programmable Gate Array) TDC is implemented on TCM to accurately acquire the time interval between the asynchronous T0 signal and the global synchronous clock phase. There is also an FPGA-based TDC on FDM to accurately acquire the time interval between T0 arriving at FDM and the first sample point of the detector signal, the over threshold time of signal is obtained offline. This method for TOF measurement is efficient and not needed for additional modules. Test result shows the accuracy of TOF is sub-nanosecond and can meet the requirement for Back-n at CSNS. Comment: 4 pages, 13 figures, 21st IEEE Real Time Conference
Keywords	Physics - Instrumentation and Detectors ; Electrical Engineering and Systems Science - Signal Processing
Subject code	530
Publishing date	2018-06-24
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: [Meta-analysis of β-blockers for the primary prevention of liver cirrhosis with clinically significant portal hypertension with no or small esophageal varices].

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Article ; Online: Clinicopathological characteristics and prognosis of schistosomal colorectal cancer.

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Article: [Development and validation of a prognostic prediction model for patients with stage Ⅰ to Ⅲ colon cancer incorporating high-risk pathological features].

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Article ; Online: Effects of melatonin on spinal cord injury-induced oxidative damage in mice testis.

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Article ; Online: Identification of smut-responsive genes in sugarcane using cDNA-SRAP.

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Article ; Online: Effect of electrochemical structuring of Ti6Al4V on osteoblast behaviour in vitro.

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Book ; Online: Electronics of Time-of-flight Measurement for Back-n at CSNS

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