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  1. AU="Wu, Qimin"
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  1. Article ; Online: Enantioselective Syntheses of 2-Azabicyclo[2.2.1]heptanes via Brønsted Acid Catalyzed Ring-Opening of

    Cai, Min / Ma, Jiao / Wu, Qimin / Lin, Aijun / Yao, Hequan

    Organic letters

    2022  Volume 24, Issue 48, Page(s) 8791–8795

    Abstract: A chiral phosphoric acid-catalyzed ring-opening ... ...

    Abstract A chiral phosphoric acid-catalyzed ring-opening of
    MeSH term(s) Heptanes ; Epoxy Compounds
    Chemical Substances Heptanes ; Epoxy Compounds
    Language English
    Publishing date 2022-11-22
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.2c03529
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Palladium-catalyzed intramolecular asymmetric hydrocyclopropanylation of alkynes: synthesis of cyclopropane-fused γ-lactams.

    Lin, Han-Ze / Qi, Zhuang / Wu, Qi-Min / Jiang, Yong-Yu / Peng, Jin-Bao

    Chemical science

    2023  Volume 14, Issue 27, Page(s) 7564–7568

    Abstract: A palladium-catalyzed intramolecular asymmetric hydrocyclopropanylation of ... ...

    Abstract A palladium-catalyzed intramolecular asymmetric hydrocyclopropanylation of alkynes
    Language English
    Publishing date 2023-06-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d3sc02168h
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  3. Article: Vibrio vulnificus

    Wu, Qimin / Wu, Yan / Zhang, Tingting / Wu, Fei / Zhang, Yiquan / Lu, Renfei

    Heliyon

    2023  Volume 9, Issue 8, Page(s) e18905

    Abstract: ... Vibrio ... ...

    Abstract Vibrio vulnificus
    Language English
    Publishing date 2023-08-02
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e18905
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  4. Article ; Online: Atroposelective Synthesis of Axially Chiral Styrenes by Platinum- Catalyzed Stereoselective Hydrosilylation of Internal Alkynes.

    Wu, Qimin / Zhang, Qi / Yin, Shuxin / Lin, Aijun / Gao, Shang / Yao, Hequan

    Angewandte Chemie (International ed. in English)

    2023  Volume 62, Issue 30, Page(s) e202305518

    Abstract: Hydrofunctionalization of alkynes is one of the most efficient ways to access axially chiral styrenes with open-chained olefins. While great advances have been achieved for 1-alkynylnaphthalen-2-ols and analogues, atroposelective hydrofunctionalization ... ...

    Abstract Hydrofunctionalization of alkynes is one of the most efficient ways to access axially chiral styrenes with open-chained olefins. While great advances have been achieved for 1-alkynylnaphthalen-2-ols and analogues, atroposelective hydrofunctionalization of unactivated internal alkynes lags. Herein we reported a platinum-catalyzed atroposelective hydrosilylation of unactivated internal alkynes for the first time. With monodentate TADDOL-derived phosphonite L1 used as a chiral ligand, various axially chiral styrenes were achieved in excellent enantioselectivities with high E-selectivities. Control experiments showed that the NH-arylamide groups have significant effects on both the yields and enantioselectivities and could act as directing groups. The potential utilities of the products were shown by the transformations of the amide motifs of the products.
    Language English
    Publishing date 2023-06-15
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202305518
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  5. Article ; Online: CD40-targeting magnetic nanoparticles for MRI/optical dual-modality molecular imaging of vulnerable atherosclerotic plaques.

    Wu, Qimin / Pan, Wei / Wu, Guifu / Wu, Fensheng / Guo, Yousheng / Zhang, Xinxia

    Atherosclerosis

    2023  Volume 369, Page(s) 17–26

    Abstract: Background and aims: Acute coronary syndrome caused by vulnerable plaque rupture or erosion is a leading cause of death worldwide. CD40 has been reported to be highly expressed in atherosclerotic plaques and closely related to plaque stability. ... ...

    Abstract Background and aims: Acute coronary syndrome caused by vulnerable plaque rupture or erosion is a leading cause of death worldwide. CD40 has been reported to be highly expressed in atherosclerotic plaques and closely related to plaque stability. Therefore, CD40 is expected to be a potential target for the molecular imaging of vulnerable plaques in atherosclerosis. We aimed to design a CD40-targeted magnetic resonance imaging (MRI)/optical multimodal molecular imaging probe and explore its ability to detect and target vulnerable atherosclerotic plaques.
    Methods: CD40-Cy5.5 superparamagnetic iron oxide nanoparticles (CD40-Cy5.5-SPIONs), which comprise a CD40-targeting multimodal imaging contrast agent, were constructed by conjugating CD40 antibody and Cy5.5-N-hydroxysuccinimide ester with SPIONs. During this in vitro study, we observed the binding ability of CD40-Cy5.5-SPIONs with RAW 264.7 cells and mouse aortic vascular smooth muscle cells (MOVAS) after different treatments, using confocal fluorescence microscopy and Prussian blue staining. An in vivo study involving ApoE
    Results: CD40-Cy5.5-SPIONs bind specifically to tumor necrosis factor (TNF)-α-treated macrophages and smooth muscle cells. Fluorescence imaging results showed that, compared with the control group and the atherosclerosis group injected with non-specific bovine serum albumin (BSA)-Cy5.5-SPIONs, the atherosclerotic group injected with CD40-Cy5.5-SPIONs had a stronger fluorescence signal. T2-weighted images showed that the carotid arteries of atherosclerotic mice injected with CD40-Cy5.5-SPIONs had a significant substantial T2 contrast enhancement effect.
    Conclusions: CD40-Cy5.5-SPIONs could potentially serve as an effective MRI/optical probe for vulnerable atherosclerotic plaques during non-invasive detection.
    MeSH term(s) Animals ; Mice ; Plaque, Atherosclerotic/metabolism ; Magnetite Nanoparticles ; Contrast Media/pharmacology ; Contrast Media/chemistry ; Atherosclerosis/metabolism ; Magnetic Resonance Imaging/methods ; Molecular Imaging ; Nanoparticles/chemistry
    Chemical Substances CY5.5 cyanine dye ; Magnetite Nanoparticles ; Contrast Media
    Language English
    Publishing date 2023-02-23
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80061-2
    ISSN 1879-1484 ; 0021-9150
    ISSN (online) 1879-1484
    ISSN 0021-9150
    DOI 10.1016/j.atherosclerosis.2023.02.008
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    Zs.A 226: Show issues Location:
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  6. Article: Complete genome sequence and comparative analysis of a

    Wu, Fei / Zhang, Tingting / Wu, Qimin / Li, Xue / Zhang, Miaomiao / Luo, Xi / Zhang, Yiquan / Lu, Renfei

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1240835

    Abstract: ... Vibrio ... ...

    Abstract Vibrio vulnificus
    Language English
    Publishing date 2023-10-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1240835
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  7. Article: Quorum sensing and QsvR tightly control the transcription of

    Zhang, Yiquan / Xue, Xingfan / Sun, Fengjun / Li, Xue / Zhang, Miaomiao / Wu, Qimin / Zhang, Tingting / Luo, Xi / Lu, Renfei

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1123524

    Abstract: Vibrio parahaemolyticus, a Gram-negative, halophilic bacterium, is a leading cause of acute gastroenteritis in humans. AphA and OpaR are the master quorum sensing (QS) regulators operating at low cell density (LCD) and high cell density (HCD), ... ...

    Abstract Vibrio parahaemolyticus, a Gram-negative, halophilic bacterium, is a leading cause of acute gastroenteritis in humans. AphA and OpaR are the master quorum sensing (QS) regulators operating at low cell density (LCD) and high cell density (HCD), respectively. QsvR is an AraC-type protein that integrates into the QS system to control gene expression by directly controlling the transcription of
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1123524
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  8. Article: QsvR and OpaR coordinately repress biofilm formation by

    Zhang, Miaomiao / Xue, Xingfan / Li, Xue / Wu, Qimin / Zhang, Tingting / Yang, Wenhui / Hu, Lingfei / Zhou, Dongsheng / Lu, Renfei / Zhang, Yiquan

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1079653

    Abstract: Mature biofilm formation ... ...

    Abstract Mature biofilm formation by
    Language English
    Publishing date 2023-02-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1079653
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  9. Article ; Online: The phase variation between wrinkly and smooth colony phenotype affects the virulence of Vibrio parahaemolyticus.

    Wu, Qimin / Li, Xue / Zhang, Miaomiao / Xue, Xingfan / Zhang, Tingting / Sun, Hui / Xiong, Shuhui / Lu, Renfei / Zhang, Yiquan / Zhou, Min

    Archives of microbiology

    2023  Volume 205, Issue 12, Page(s) 382

    Abstract: Vibrio parahaemolyticus, the causative agent of seafood-associated gastroenteritis, undergoes wrinkly and smooth colony switching on the plate. The wrinkly spreader grew faster, had stronger motility and biofilm capacity when compared with the smooth one. ...

    Abstract Vibrio parahaemolyticus, the causative agent of seafood-associated gastroenteritis, undergoes wrinkly and smooth colony switching on the plate. The wrinkly spreader grew faster, had stronger motility and biofilm capacity when compared with the smooth one. However, whether the two phenotypes differ in their virulence still needs to be further investigated. In this study, the data showed that the smooth spreader had stronger virulence phenotypes, including the cytotoxicity against HeLa cells, antibacterial activity against E. coli, adhesive capacity toward HeLa cells, and lethality in zebrafish, relative to the wrinkly one. However, the colony morphology variation had no influence on the haemolytic activity. The mRNA levels of major virulence genes including T3SS1, T6SS1, and T6SS2 were significantly enhanced in the smooth colonies relative to those in the wrinkly colonies. Taken together, the presented work highlighted the different virulence profiles of the wrinkly and smooth colony phenotypes.
    MeSH term(s) Humans ; Animals ; Virulence ; Vibrio parahaemolyticus/genetics ; HeLa Cells ; Phase Variation ; Zebrafish ; Escherichia coli ; Virulence Factors/genetics ; Phenotype ; Bacterial Proteins/genetics
    Chemical Substances Virulence Factors ; Bacterial Proteins
    Language English
    Publishing date 2023-11-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124824-8
    ISSN 1432-072X ; 0302-8933
    ISSN (online) 1432-072X
    ISSN 0302-8933
    DOI 10.1007/s00203-023-03719-1
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 805: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Cross Validation of Stress Drop Estimates and Interpretations for the 2011 Prague, OK, Earthquake Sequence Using Multiple Methods

    Pennington, Colin N. / Chen, Xiaowei / Abercrombie, Rachel E. / Wu, Qimin

    Journal of geophysical research. 2021 Mar., v. 126, no. 3

    2021  

    Abstract: We compare source parameter estimates for earthquakes in the 2011 Prague Mw 5.7, Oklahoma, sequence to investigate random uncertainty and systematic bias, and resolve reliable relative variations in stress drop. Source parameters provide insight into the ...

    Abstract We compare source parameter estimates for earthquakes in the 2011 Prague Mw 5.7, Oklahoma, sequence to investigate random uncertainty and systematic bias, and resolve reliable relative variations in stress drop. Source parameters provide insight into the earthquake rupture processes but large variations between studies occur. The Prague earthquake sequence is a prime example of this, with different studies reaching contrasting interpretations of the effects of injection on source parameters. We examine the Prague earthquake sequence using a single coherent catalog for all the events detected by the Oklahoma Geological Survey (OGS) and McMahon et al. (2017). We use three principal approaches to estimate stress drop in order to understand the biases of each: a spectral decomposition method based on stacking, individual event spectral modeling, and a spectral ratio method based on highly correlated events. We also compare our results with previous studies for the Prague sequences aftershocks, as well as past results for the Mw 4.8 foreshock and Mw 4.8 aftershock and Mw 5.7 mainshock. The absolute values of stress drop vary significantly between methods, but the relative patterns remain consistent, except when low quality or low bandwidth data are included. The consistent relative patterns reveal that the stress drops of aftershocks are dependent on the fault orientation and the proximity of the events to the mainshocks slip. These results indicate that fault structure as well as past events play an important role in stress drop patterns.
    Keywords earthquakes ; research ; surveys ; uncertainty ; Oklahoma
    Language English
    Dates of publication 2021-03
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ISSN 2169-9313
    DOI 10.1029/2020JB020888
    Database NAL-Catalogue (AGRICOLA)

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