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  1. Article ; Online: Determining the factors affecting customer satisfaction using an extraction-based feature selection approach.

    Wu, Weishen / Riantama, Dalianus

    PeerJ. Computer science

    2022  Volume 8, Page(s) e850

    Abstract: The coronavirus disease 2019 (COVID-19) causes tremendous damages to the world, including threats to human's health and daily activities. Most industries have been affected by this pandemic, particularly the tourism industry. The online travel agencies ( ... ...

    Abstract The coronavirus disease 2019 (COVID-19) causes tremendous damages to the world, including threats to human's health and daily activities. Most industries have been affected by this pandemic, particularly the tourism industry. The online travel agencies (OTAs) have suffered from the global tourism market crisis by air travel lockdown in many countries. How online travel agencies can survive at stake and prepare for the post-COVID-19 future has emerged as an urgent issue. This study aims to examine the critical factors of customers' satisfaction to OTAs during the COVID-19 pandemic. A text mining method for feature selection, namely LASSO, was used to deal with online customer reviews and to extract factors that shape customers' satisfaction to OTAs. Results showed that refunds, promptness, easiness and assurance were ranked as the most competitive factors of customers' satisfaction, followed by bad reviews & cheap and excellent service & comparison. New factors to customers' satisfaction were revealed during the global tourism recession. Findings provide OTAs guidelines to reset services priorities during the pandemic crisis.
    Language English
    Publishing date 2022-01-25
    Publishing country United States
    Document type Journal Article
    ISSN 2376-5992
    ISSN (online) 2376-5992
    DOI 10.7717/peerj-cs.850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: What motivates customers to repurchase online under social distancing?

    Wu, Weishen / Widiatmo, Gumilang / Riantama, Dalianus

    Frontiers in psychology

    2023  Volume 14, Page(s) 1155302

    Abstract: Global e-commerce is growing rapidly during the COVID pandemic. Previous research on customers' online shopping decisions rarely considered social distancing. To investigate customers' continued intention toward online purchases while socially isolated, ... ...

    Abstract Global e-commerce is growing rapidly during the COVID pandemic. Previous research on customers' online shopping decisions rarely considered social distancing. To investigate customers' continued intention toward online purchases while socially isolated, we propose a framework based on the UTAUT model. A survey of 330 valid samples was collected through an online survey among internet users during a period of social distancing in Indonesia. Hypotheses were validated using a structural equation modeling approach. The results showed that social contingency is the most influential factor on customers' intention to repurchase online under social restriction conditions, followed by customer perceived value and other significant factors. The findings contribute to providing a new understanding of customers' online repurchase intentions when they are in a contingency situation.
    Language English
    Publishing date 2023-07-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1155302
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Analysis of re-positive nucleic acid conversion in patients recovered from COVID-19 in Tianjin

    ZHAO Ying / WU Weishen / HE Haiyan / WEI Zhaofei / ZHANG Guoping

    Di-san junyi daxue xuebao, Vol 42, Iss 9, Pp 879-

    2020  Volume 882

    Abstract: Objective To analyze the re-positive nucleic acid cases in patients recovered from coronavirus disease 2019 (COVID-19) in Tianjin, and to provide suggestions on making prevention and control strategies. Methods Among the 109 confirmed COVID-19 patients ... ...

    Abstract Objective To analyze the re-positive nucleic acid cases in patients recovered from coronavirus disease 2019 (COVID-19) in Tianjin, and to provide suggestions on making prevention and control strategies. Methods Among the 109 confirmed COVID-19 patients in Tianjin who were reported by the China Information System for Disease Control and Prevention, 8 patients re-positive for nucleic acid test after discharge were enrolled in this study. Their conditions after discharge were monitored by our group, including epidemiology, onset time, symptoms, and results of regular viral nucleic acid test. The epidemiological characteristics were analyzed. Results As of March 7, 2020, the positive rate of re-positive nucleic acid conversion in patients recovered from COVID-19 was 7.34% (8/109). The median days of disease was 20.5 (14.0~28.0) d in 8 re-positive cases, which was not statistically different from those with negative results after discharge. Among the viral nucleic acid-positive samples, fecal specimens or anal swabs accounted for 62.50% (5/8), and throat swabs for 37.50% (3/8). All 8 cases had identified epidemiological history. When the nucleic acid re-positive, 12.50% of them (1/8) had clinical symptoms, but they did not cause any secondary transmission. Conclusion Re-positiveness for nucleic acid test are found in the COVID-19 patients after discharge in Tianjin, but no one causes further transmission till now. It is recommended to add standards for fecal nucleic acid test during discharge and quarantine, regularly nucleic acid detection after the patient is discharged from the hospital.
    Keywords corona virus disease 2019 ; sars-cov-2 ; nucleic acid ; re-positive ; tianjin ; epidemiology ; Medicine (General) ; R5-920
    Subject code 610
    Language Chinese
    Publishing date 2020-05-01T00:00:00Z
    Publisher Editorial Office of Journal of Third Military Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Investigating SARS-CoV-2 persistent contamination in different indoor environments.

    Liu, He / Fei, Chunnan / Chen, Yinglei / Luo, Shengmao / Yang, Tao / Yang, Lei / Liu, Jun / Ji, Xueyue / Wu, Weishen / Song, Jia

    Environmental research

    2021  Volume 202, Page(s) 111763

    Abstract: Environmental contamination caused by COVID-19 patients could be a medium of transmission. Previous reports of SARS-CoV-2 in environmental surfaces were about short-term contamination. This study investigated SARS-CoV-2 RNA existence in room-temperature ... ...

    Abstract Environmental contamination caused by COVID-19 patients could be a medium of transmission. Previous reports of SARS-CoV-2 in environmental surfaces were about short-term contamination. This study investigated SARS-CoV-2 RNA existence in room-temperature and low-temperature environments long after exposure (>28 days). A department store, where a COVID-19 outbreak was occurred in January 2020 (the epicenter of 43 COVID-19 patients), and a patient's apartment were included as room-temperature environments after being blocked for 57 days and 48 days, respectively. Seven cold storages and imported frozen foods inside were included as low-temperature environments (under -18 °C). Twenty food markets with potential contamination of imported frozen foods were also included to study the consecutive contamination. Information about temperature, relative humidity, and the number of days of environmental samples since the last exposure was collected and analyzed. In sum, 11,808 swab samples were collected before disinfection, of which 35 samples were positive. Persistent contamination of SARS-CoV-2 RNA was identified in the apartment (6/19), the department store (3/50), food packages in cold storages (23/1360), environmental surfaces of cold storages (2/345), and a package in the food market (1/10,034). Two positive samples were isolated from the bathroom of the apartment (66.7 %, 2/3), and doorknobs were proved with contamination in the apartment (40 %, 2/5) and cold storage (33.3 %, 1/3). The epidemiology information and environmental contamination results of an imported frozen food related COVID-19 case (138th COVID-19 patient in Tianjin) were analyzed. Based on the Ct values, the number of copies of two target genes was calculated by standard curves and linear regressions. In conclusion, SARS-CoV-2 RNA can be detected in room-temperature environments at least 57 days after the last exposure, much longer than previous reports. Based on the results of this study and previous studies, infectious SARS-CoV-2 could exist for at least 60 days on the surface of cold-chain food packages. Doorknobs and toilets (bathrooms) were important positions in COVID-19 control. High-risk populations of cold-chain-related logistic operations, such as porters, require strict prevention and high-level personal protection.
    MeSH term(s) COVID-19 ; Disinfection ; Environmental Pollution ; Humans ; RNA, Viral ; SARS-CoV-2
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2021-07-28
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2021.111763
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Investigating SARS-CoV-2 persistent contamination in different indoor environments

    Liu, He / Fei, Chunnan / Chen, Yinglei / Luo, Shengmao / Yang, Tao / Yang, Lei / Liu, Jun / Ji, Xueyue / Wu, Weishen / Song, Jia

    Environmental research. 2021 Nov., v. 202

    2021  

    Abstract: Environmental contamination caused by COVID-19 patients could be a medium of transmission. Previous reports of SARS-CoV-2 in environmental surfaces were about short-term contamination. This study investigated SARS-CoV-2 RNA existence in room-temperature ... ...

    Abstract Environmental contamination caused by COVID-19 patients could be a medium of transmission. Previous reports of SARS-CoV-2 in environmental surfaces were about short-term contamination. This study investigated SARS-CoV-2 RNA existence in room-temperature and low-temperature environments long after exposure (>28 days). A department store, where a COVID-19 outbreak was occurred in January 2020 (the epicenter of 43 COVID-19 patients), and a patient's apartment were included as room-temperature environments after being blocked for 57 days and 48 days, respectively. Seven cold storages and imported frozen foods inside were included as low-temperature environments (under −18 °C). Twenty food markets with potential contamination of imported frozen foods were also included to study the consecutive contamination. Information about temperature, relative humidity, and the number of days of environmental samples since the last exposure was collected and analyzed. In sum, 11,808 swab samples were collected before disinfection, of which 35 samples were positive. Persistent contamination of SARS-CoV-2 RNA was identified in the apartment (6/19), the department store (3/50), food packages in cold storages (23/1360), environmental surfaces of cold storages (2/345), and a package in the food market (1/10,034). Two positive samples were isolated from the bathroom of the apartment (66.7 %, 2/3), and doorknobs were proved with contamination in the apartment (40 %, 2/5) and cold storage (33.3 %, 1/3). The epidemiology information and environmental contamination results of an imported frozen food related COVID-19 case (138th COVID-19 patient in Tianjin) were analyzed. Based on the Ct values, the number of copies of two target genes was calculated by standard curves and linear regressions. In conclusion, SARS-CoV-2 RNA can be detected in room-temperature environments at least 57 days after the last exposure, much longer than previous reports. Based on the results of this study and previous studies, infectious SARS-CoV-2 could exist for at least 60 days on the surface of cold-chain food packages. Doorknobs and toilets (bathrooms) were important positions in COVID-19 control. High-risk populations of cold-chain-related logistic operations, such as porters, require strict prevention and high-level personal protection.
    Keywords COVID-19 infection ; RNA ; Severe acute respiratory syndrome coronavirus 2 ; ambient temperature ; cold ; cold chain ; cold storage ; disinfection ; epidemiology ; frozen foods ; markets ; patients ; pollution ; relative humidity ; research ; China
    Language English
    Dates of publication 2021-11
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2021.111763
    Database NAL-Catalogue (AGRICOLA)

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  6. Article: Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase

    Wu, Wei-Shen / Chi-Huey Wong / Ting-Jen R. Cheng / Wei-Chieh Cheng

    Journal of the American Chemical Society. 2018 Feb. 28, v. 140, no. 8

    2018  

    Abstract: The rise of antibiotic resistance has created a mounting crisis across the globe and an unmet medical need for new antibiotics. As part of our efforts to develop new antibiotics to target the uncharted surface bacterial transglycosylase, we report an ... ...

    Abstract The rise of antibiotic resistance has created a mounting crisis across the globe and an unmet medical need for new antibiotics. As part of our efforts to develop new antibiotics to target the uncharted surface bacterial transglycosylase, we report an affinity-based ligand screen method using penicillin-binding proteins immobilized on beads to selectively isolate the binders from complex natural products. In combination with mass spectrometry and assays with moenomycin A and salicylanilide analogues (1–10) as reference inhibitors, we isolated four potent antibacterials confirmed to be benastatin derivatives (11–13) and albofungin (14). Compounds 11 and 14 were effective antibiotics against a broad-spectrum of Gram-positive and Gram-negative bacteria, including Acinetobacter baumannii, Clostridium difficile, Staphylococcus aureus, and drug-resistant strains with minimum inhibitory concentrations in the submicromolar to nanomolar range.
    Keywords Acinetobacter baumannii ; antibiotic resistance ; antibiotics ; Clostridium difficile ; Gram-negative bacteria ; ligands ; mass spectrometry ; minimum inhibitory concentration ; proteins ; Staphylococcus aureus
    Language English
    Dates of publication 2018-0228
    Size p. 2752-2755.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.7b13205
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Unblocking Barriers of Access to Hepatitis C Treatment in China: Lessons Learned from Tianjin.

    Zhang, Peiwen / Guo, Ran / Lian, Jun / Zhi, Mengjia / Lu, Chengzhen / Wu, Weishen / Wang, Lihong / Chan, Polin / Chen, Zhongdan / Sun, Jing

    Annals of global health

    2020  Volume 86, Issue 1, Page(s) 36

    Abstract: Background: The high price is a critical barrier of access to new direct-anting-antiviral (DAA) therapies for hepatitis C for both the patients and the society. Many countries continue to face the challenge of financing such expensive medicines. Such ... ...

    Abstract Background: The high price is a critical barrier of access to new direct-anting-antiviral (DAA) therapies for hepatitis C for both the patients and the society. Many countries continue to face the challenge of financing such expensive medicines. Such examples include both high-income and middle-income countries. Existing evidence about the efforts of China to address this challenge is limited. To our knowledge, this is the first detailed description of a novel financing model and comprehensive analysis of its impact on patient financial burden of hepatitis C treatment in China.
    Objective: To examine the evolution of approaches to navigating patients' barriers of access to DAA-based treatment of hepatitis C in Tianjin City, China.
    Methods: Review of publicly available literature, including published and grey literature. Conduct on-site data extraction and key informant interview. The patient financial burden of hepatitis C treatment was analyzed. The financial burden of hepatitis C patients with different treatment models and health insurance financing models was measured by calculating the number of annual income to cover patient out-of-pocket (OOP) expenditure for the standard treatment course accordingly.
    Findings: Tianjin is the first area to pilot a capitated provider payment program for the treatment of hepatitis C. Through which, the retirees and employees spend 0.7 and 1.0 months of their salary, and residents spend 5.6-6.8 months of their salary for the treatment, the financial burden of patients were much relieved. By the end of March 2019, the first-year pilot program had 876 hepatitis C patients registered the new insurance coverage and treated in Tianjin.
    Conclusions: The study showed that the financial barriers of access to new hepatitis C treatment for patients could be unblocked with government commitment and novel financing models. International experiences demonstrated that centralized bulk procurement is a good leverage for price negotiation, primarily when using innovative payment approaches. To replicate the initial success of Tianjin, continued efforts are needed for stronger strategic price negotiation, preferably at central level. The case of Tianjin brings implications to the other areas of China and even other developing countries that government commitment, novel financing model and pooled procurement are critical elements of stronger purchasing power and a better secure of treatment.
    MeSH term(s) Antiviral Agents/economics ; Antiviral Agents/therapeutic use ; Capitation Fee ; China ; Drug Costs ; Fee-for-Service Plans ; Health Expenditures ; Health Services Accessibility/economics ; Healthcare Financing ; Hepatitis C, Chronic/drug therapy ; Insurance, Health/economics ; Pilot Projects
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2020-04-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2821756-1
    ISSN 2214-9996 ; 2214-9996
    ISSN (online) 2214-9996
    ISSN 2214-9996
    DOI 10.5334/aogh.2763
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase.

    Wu, Wei-Shen / Cheng, Wei-Chieh / Cheng, Ting-Jen R / Wong, Chi-Huey

    Journal of the American Chemical Society

    2018  Volume 140, Issue 8, Page(s) 2752–2755

    Abstract: The rise of antibiotic resistance has created a mounting crisis across the globe and an unmet medical need for new antibiotics. As part of our efforts to develop new antibiotics to target the uncharted surface bacterial transglycosylase, we report an ... ...

    Abstract The rise of antibiotic resistance has created a mounting crisis across the globe and an unmet medical need for new antibiotics. As part of our efforts to develop new antibiotics to target the uncharted surface bacterial transglycosylase, we report an affinity-based ligand screen method using penicillin-binding proteins immobilized on beads to selectively isolate the binders from complex natural products. In combination with mass spectrometry and assays with moenomycin A and salicylanilide analogues (1-10) as reference inhibitors, we isolated four potent antibacterials confirmed to be benastatin derivatives (11-13) and albofungin (14). Compounds 11 and 14 were effective antibiotics against a broad-spectrum of Gram-positive and Gram-negative bacteria, including Acinetobacter baumannii, Clostridium difficile, Staphylococcus aureus, and drug-resistant strains with minimum inhibitory concentrations in the submicromolar to nanomolar range.
    MeSH term(s) Acinetobacter baumannii/drug effects ; Acinetobacter baumannii/enzymology ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/isolation & purification ; Anti-Bacterial Agents/pharmacology ; Bambermycins/chemistry ; Bambermycins/isolation & purification ; Bambermycins/pharmacology ; Clostridium difficile/drug effects ; Clostridium difficile/enzymology ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/isolation & purification ; Enzyme Inhibitors/pharmacology ; Glycosyltransferases/antagonists & inhibitors ; Glycosyltransferases/metabolism ; Microbial Sensitivity Tests ; Molecular Structure ; Salicylanilides/chemistry ; Salicylanilides/isolation & purification ; Salicylanilides/pharmacology ; Staphylococcus aureus/drug effects ; Staphylococcus aureus/enzymology ; Structure-Activity Relationship ; Xanthenes/chemistry ; Xanthenes/isolation & purification ; Xanthenes/pharmacology
    Chemical Substances Anti-Bacterial Agents ; Enzyme Inhibitors ; Salicylanilides ; Xanthenes ; Bambermycins (11015-37-5) ; moenomycin A (2RO799DN06) ; albofungin (E36843J982) ; Glycosyltransferases (EC 2.4.-) ; salicylanilide (LHP8NEY345)
    Language English
    Publishing date 2018--28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.7b13205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Towards new antibiotics targeting bacterial transglycosylase: Synthesis of a Lipid II analog as stable transition-state mimic inhibitor.

    Wang, Xiaolei / Krasnova, Larissa / Wu, Kevin Binchia / Wu, Wei-Shen / Cheng, Ting-Jen / Wong, Chi-Huey

    Bioorganic & medicinal chemistry letters

    2018  Volume 28, Issue 16, Page(s) 2708–2712

    Abstract: Described here is the asymmetric synthesis of iminosugar 2b, a Lipid II analog, designed to mimic the transition state of transglycosylation catalyzed by the bacterial transglycosylase. The high density of functional groups, together with a rich ... ...

    Abstract Described here is the asymmetric synthesis of iminosugar 2b, a Lipid II analog, designed to mimic the transition state of transglycosylation catalyzed by the bacterial transglycosylase. The high density of functional groups, together with a rich stereochemistry, represents an extraordinary challenge for chemical synthesis. The key 2,6-anti- stereochemistry of the iminosugar ring was established through an iridium-catalyzed asymmetric allylic amination. The developed synthetic route is suitable for the synthesis of focused libraries to enable the structure-activity relationship study and late-stage modification of iminosugar scaffold with variable lipid, peptide and sugar substituents. Compound 2b showed 70% inhibition of transglycosylase from Acinetobacter baumannii, providing a basis for further improvement.
    MeSH term(s) Acinetobacter baumannii/drug effects ; Acinetobacter baumannii/enzymology ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Dose-Response Relationship, Drug ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Glycosyltransferases/antagonists & inhibitors ; Glycosyltransferases/metabolism ; Microbial Sensitivity Tests ; Models, Molecular ; Molecular Conformation ; Stereoisomerism ; Structure-Activity Relationship ; Uridine Diphosphate N-Acetylmuramic Acid/analogs & derivatives ; Uridine Diphosphate N-Acetylmuramic Acid/chemical synthesis ; Uridine Diphosphate N-Acetylmuramic Acid/chemistry ; Uridine Diphosphate N-Acetylmuramic Acid/pharmacology
    Chemical Substances Anti-Bacterial Agents ; Enzyme Inhibitors ; Uridine Diphosphate N-Acetylmuramic Acid ; muramyl-NAc-(pentapeptide)pyrophosphoryl-undecaprenol ; Glycosyltransferases (EC 2.4.-)
    Language English
    Publishing date 2018-03-15
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1063195-1
    ISSN 1464-3405 ; 0960-894X
    ISSN (online) 1464-3405
    ISSN 0960-894X
    DOI 10.1016/j.bmcl.2018.03.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Structure-based design of bacterial transglycosylase inhibitors incorporating biphenyl, amine linker and 2-alkoxy-3-phosphorylpropanoate moieties.

    Yu, Jui-Yin / Cheng, Hsiu-Jung / Wu, Huei-Ru / Wu, Wei-Shen / Lu, Jui-Wen / Cheng, Ting-Jen / Wu, Ying-Ta / Fang, Jim-Min

    European journal of medicinal chemistry

    2018  Volume 150, Page(s) 729–741

    Abstract: Transglycosylase (TGase) is essential to biosynthesis of peptidoglycan for formation of bacterial cell wall. Moenomycin is a potent TGase inhibitor, but not used in clinic treatment due to its poor pharmacokinetics. The E-F disaccharide, phosphoglycerate ...

    Abstract Transglycosylase (TGase) is essential to biosynthesis of peptidoglycan for formation of bacterial cell wall. Moenomycin is a potent TGase inhibitor, but not used in clinic treatment due to its poor pharmacokinetics. The E-F disaccharide, phosphoglycerate and lipid tail in moenomycin are crucial elements for TGase inhibition and antibacterial activity. Based on this scaffold, a series of truncated mimics comprising biphenyl, amine linker and 2-alkoxy-3-phosphorylpropanoate moieties were designed to test their TGase inhibitory activity. In this design, the phosphorylpropanoate group is a surrogate of phosphoglycerate with improved stability. A library of lipid tails can be constructed by a straightforward approach using Cu(I)-catalyzed (3 + 2) cycloaddition reactions, and the as-synthesized triazole ring can provide additional hydrogen bonds in the TGase active site. Our molecular docking experiments reveal that the biphenyl group provides π-π and π-cation interactions to act as a simplified alternative of the C-E disaccharide in moenomycin. To play the role of the oxonium transition state in transglycosylation, the amine linker exists as a positively charged species in physiological condition to attain electrostatic interactions with acidic residues. In this study, two biphenyl-linked 2-alkoxy-3-phosphorylpropanoate compounds (8 and 10) are found to exhibit modest inhibitory activity (IC
    MeSH term(s) Acinetobacter baumannii/enzymology ; Amines/chemistry ; Amines/pharmacology ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Biphenyl Compounds/chemistry ; Biphenyl Compounds/pharmacology ; Dose-Response Relationship, Drug ; Drug Design ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Glycosyltransferases/antagonists & inhibitors ; Glycosyltransferases/metabolism ; Microbial Sensitivity Tests ; Molecular Structure ; Organophosphorus Compounds/chemistry ; Organophosphorus Compounds/pharmacology ; Propionates/chemistry ; Propionates/pharmacology ; Staphylococcus aureus/drug effects ; Structure-Activity Relationship
    Chemical Substances Amines ; Anti-Bacterial Agents ; Biphenyl Compounds ; Enzyme Inhibitors ; Organophosphorus Compounds ; Propionates ; diphenyl (2L9GJK6MGN) ; Glycosyltransferases (EC 2.4.-)
    Language English
    Publishing date 2018-04-25
    Publishing country France
    Document type Journal Article
    ZDB-ID 188597-2
    ISSN 1768-3254 ; 0009-4374 ; 0223-5234
    ISSN (online) 1768-3254
    ISSN 0009-4374 ; 0223-5234
    DOI 10.1016/j.ejmech.2018.03.034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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