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  1. Article ; Online: Letter by Wu and Yu Regarding Article, "Smoking Causes Fatal Subarachnoid Hemorrhage: A Case-Control Study of Finnish Twins".

    Wu, Yuehui / Yu, Xinyu

    Stroke

    2021  Volume 52, Issue 2, Page(s) e73

    MeSH term(s) Case-Control Studies ; Finland/epidemiology ; Humans ; Smoking/adverse effects ; Subarachnoid Hemorrhage/epidemiology ; Twins
    Language English
    Publishing date 2021-01-25
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.120.032874
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Brain functional connectivity and network characteristics changes after vagus nerve stimulation in patients with refractory epilepsy.

    Ding, Yongqiang / Guo, Kunlin / Wang, Xinjun / Chen, Mingming / Li, Xinxiao / Wu, Yuehui

    Translational neuroscience

    2023  Volume 14, Issue 1, Page(s) 20220308

    Abstract: Objective: This study aims to investigate the impact of vagus nerve stimulation (VNS) on the connectivity and small-world metrics of brain functional networks during seizure periods.: Methods: Ten refractory epilepsy patients underwent video ... ...

    Abstract Objective: This study aims to investigate the impact of vagus nerve stimulation (VNS) on the connectivity and small-world metrics of brain functional networks during seizure periods.
    Methods: Ten refractory epilepsy patients underwent video encephalographic monitoring before and after VNS treatment. The 2-min electroencephalogram segment containing the ictal was selected for each participant, resulting in a total of 20 min of seizure data. The weighted phase lag index (wPLI) and small-world metrics were calculated for the whole frequency band and different frequency bands (delta, theta, alpha, beta, and gamma). Finally, the relevant metrics were statistically analyzed, and the false discovery rate was used to correct for differences after multiple comparisons.
    Results: In the whole band, the wPLI was notably enhanced, and the network metrics, including degree (D), clustering coefficient (CC), and global efficiency (GE), increased, while characteristic path length (CPL) decreased (
    Conclusion: VNS treatment can significantly change the wPLI and small-world metrics. These findings contribute to a deeper understanding of the impact of VNS therapy on brain networks and provide objective indicators for evaluating the efficacy of VNS.
    Language English
    Publishing date 2023-09-07
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2581219-1
    ISSN 2081-6936 ; 2081-3856
    ISSN (online) 2081-6936
    ISSN 2081-3856
    DOI 10.1515/tnsci-2022-0308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Letter regarding article 'Abdominal aortic aneurysm is associated with subarachnoid hemorrhage'.

    Wu, Yuehui / Liu, Tianyu / Jiang, Xiaobing / Yu, Xinyu

    Journal of neurointerventional surgery

    2021  Volume 13, Issue 8, Page(s) e15

    MeSH term(s) Aneurysm, Ruptured ; Aortic Aneurysm, Abdominal ; Humans ; Intracranial Aneurysm/complications ; Intracranial Aneurysm/diagnostic imaging ; Subarachnoid Hemorrhage/diagnostic imaging
    Language English
    Publishing date 2021-01-08
    Publishing country England
    Document type Letter
    ZDB-ID 2514982-9
    ISSN 1759-8486 ; 1759-8478
    ISSN (online) 1759-8486
    ISSN 1759-8478
    DOI 10.1136/neurintsurg-2020-017164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Letter to the Editor Regarding "Association Between Aspirin Use and Risk of Aneurysmal Subarachnoid Hemorrhage: A Meta-Analysis".

    Wu, Yuehui / Jiang, Xiaobing / Yu, Xinyu

    World neurosurgery

    2021  Volume 146, Page(s) 394

    MeSH term(s) Aspirin/adverse effects ; Humans ; Hydrocephalus ; Subarachnoid Hemorrhage
    Chemical Substances Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2021-02-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2020.09.114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Arrangement of boundary electrodes for detection of frontal lobe disease with electrical impedance tomography.

    Shi, Yanyan / Tian, Zhiwei / Wang, Meng / Fu, Feng / Wu, Yuehui

    Journal of medical imaging (Bellingham, Wash.)

    2021  Volume 8, Issue 4, Page(s) 44501

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2021-07-06
    Publishing country United States
    Document type Journal Article
    ISSN 2329-4302
    ISSN 2329-4302
    DOI 10.1117/1.JMI.8.4.044501
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Chronobiological Patterns of Aneurysmal Subarachnoid Hemorrhage in Central China.

    Wu, Yuehui / Tang, Nan / Xia, Liangtao / Liu, Tianyu / Yu, Hao / Jiang, Xiaobing / Yu, Xinyu

    Global heart

    2022  Volume 17, Issue 1, Page(s) 29

    Abstract: Background: Aneurysmal subarachnoid hemorrhage (aSAH) is an acute and sometimes fatal cerebrovascular disease. The chronobiological patterns of aSAH are still unclear worldwide. This 15-year time-series study aims to clarify the chronobiological ... ...

    Abstract Background: Aneurysmal subarachnoid hemorrhage (aSAH) is an acute and sometimes fatal cerebrovascular disease. The chronobiological patterns of aSAH are still unclear worldwide. This 15-year time-series study aims to clarify the chronobiological patterns including seasonal, monthly, weekly, and circadian distributions of aSAH.
    Methods: We retrospectively analyzed the medical records of aSAH patients in central China. To investigate seasonal and weekly distributions, we used the χ2 goodness-of-fit test to analyze the uniformity of the onset time. To explore monthly and circadian distributions, we established Fourier models to show the rhythmicity in chronobiological patterns. Subgroup analyses were conducted to assess the impact of age, gender, hypertension statuses, and aneurysmal characteristics (number, size, and location) on the chronobiological patterns of aSAH.
    Results: A total of 1469 patients with aSAH were recruited in the study. The seasonal and monthly distribution exhibited significantly higher incidence in winter and January/December and lower incidence in summer and July. The weekly distribution of aSAH onset showed no significant uneven variation. The circadian distribution of aSAH exhibited a significant pattern (p = 0.0145), with a morning peak around 8:00, and a late afternoon peak at 16:00-20.00. The circadian rhythmicity varied in subgroups of different ages, genders, and aneurysmal locations.
    Conclusion: The occurrence of aSAH exhibits significant circannual and circadian patterns among the Chinese population. Patients with aSAH of different ages, genders, and aneurysmal locations would present different chronobiological patterns.
    MeSH term(s) China/epidemiology ; Circadian Rhythm ; Female ; Humans ; Male ; Retrospective Studies ; Seasons ; Subarachnoid Hemorrhage/epidemiology ; Subarachnoid Hemorrhage/etiology
    Language English
    Publishing date 2022-04-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2629633-0
    ISSN 2211-8179 ; 2211-8160
    ISSN (online) 2211-8179
    ISSN 2211-8160
    DOI 10.5334/gh.1117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Analysis of sodium phenylbutyrate and taurursodiol survival effect in ALS using external controls.

    Paganoni, Sabrina / Quintana, Melanie / Sherman, Alexander V / Vestrucci, Matteo / Wu, Yuehui / Timmons, Jamie / Cudkowicz, Merit

    Annals of clinical and translational neurology

    2023  Volume 10, Issue 12, Page(s) 2297–2304

    Abstract: Objective: Sodium phenylbutyrate and taurursodiol (PB and TURSO) was evaluated in amyotrophic lateral sclerosis (ALS) in the CENTAUR trial encompassing randomized placebo-controlled and open-label extension phases. On intent-to-treat (ITT) survival ... ...

    Abstract Objective: Sodium phenylbutyrate and taurursodiol (PB and TURSO) was evaluated in amyotrophic lateral sclerosis (ALS) in the CENTAUR trial encompassing randomized placebo-controlled and open-label extension phases. On intent-to-treat (ITT) survival analysis, median overall survival (OS) was 4.8 months longer and risk of death 36% lower in those originally randomized to an initial 6-month double-blind period of PB and TURSO versus placebo. To estimate PB and TURSO treatment effect without placebo-to-active crossover, we performed a post hoc survival analysis comparing PB and TURSO-randomized participants from CENTAUR and a propensity score-matched, PB and TURSO-naïve external control cohort from the Pooled Resource Open-Access ALS Clinical Trials (PRO-ACT) database.
    Methods: Clinical trial control participants from the PRO-ACT database who met prespecified eligibility criteria were propensity score matched 1:1 with PB and TURSO-randomized CENTAUR participants using prognostically significant covariates in ALS.
    Results: Baseline characteristics including propensity score-matched covariates were generally well balanced between CENTAUR PB and TURSO (n = 89) and PRO-ACT external control (n = 85) groups. Estimated median (IQR) OS was 23.54 (14.56-39.32) months in the CENTAUR PB and TURSO group and 13.15 (9.83-19.20) months in the PRO-ACT external control group; hazard of death was 52% lower in the former group (hazard ratio, 0.48; 95% CI, 0.31-0.72; p = 0.00048).
    Interpretation: This analysis suggests potentially greater survival benefit with PB and TURSO in ALS without placebo-to-active crossover than seen on ITT analysis in CENTAUR. Analyses using well-matched external controls may provide additional context for evaluating survival effects in future ALS trials.
    MeSH term(s) Humans ; Amyotrophic Lateral Sclerosis/drug therapy ; Phenylbutyrates/pharmacology ; Phenylbutyrates/therapeutic use ; Survival Analysis ; Proportional Hazards Models
    Chemical Substances sodium phenylbutyrate and taurursodiol ; Phenylbutyrates
    Language English
    Publishing date 2023-10-09
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2740696-9
    ISSN 2328-9503 ; 2328-9503
    ISSN (online) 2328-9503
    ISSN 2328-9503
    DOI 10.1002/acn3.51915
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  8. Article: Alterations in brain network functional connectivity and topological properties in DRE patients.

    Ding, Yongqiang / Guo, Kunlin / Li, Jialiang / Shan, Qiao / Guo, Yongkun / Chen, Mingming / Wu, Yuehui / Wang, Xinjun

    Frontiers in neurology

    2023  Volume 14, Page(s) 1238421

    Abstract: Objective: The study aimed to find the difference in functional network topology on interictal electroencephalographic (EEG) between patients with drug-resistant epilepsy (DRE) and healthy people.: Methods: We retrospectively analyzed the medical ... ...

    Abstract Objective: The study aimed to find the difference in functional network topology on interictal electroencephalographic (EEG) between patients with drug-resistant epilepsy (DRE) and healthy people.
    Methods: We retrospectively analyzed the medical records as well as EEG data of ten patients with DRE and recruited five sex-age-matched healthy controls (HC group). Each participant remained awake while undergoing video-electroencephalography (vEEG) monitoring. After excluding data that contained abnormal discharges, we screened EEG segments that were free of artifacts and put them together into 20-min segments. The screened data was bandpass filtered to different frequency bands (delta, theta, alpha, beta, and gamma). The weighted phase lag index (wPLI) and the network properties were calculated to evaluate changes in the topology of the functional network. Finally, the results were statistically analyzed, and the false discovery rate (FDR) was used to correct for differences after multiple comparisons.
    Results: In the full frequency band (0.5-45 Hz), the functional connectivity in the DRE group during the interictal period was significantly lower than that in the HC group (
    Conclusion: The topology structure of the functional network in DRE patients was significantly changed compared with healthy people, which was reflected in different frequency bands. It provided a theoretical basis for understanding the pathological network alterations of DRE.
    Language English
    Publishing date 2023-12-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2023.1238421
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  9. Article: The Role of Aspirin in the Management of Intracranial Aneurysms: A Systematic Review and Meta-Analyses.

    Yang, Shuwen / Liu, Tianyu / Wu, Yuehui / Xu, Nina / Xia, Liangtao / Yu, Xinyu

    Frontiers in neurology

    2021  Volume 12, Page(s) 646613

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2021-03-30
    Publishing country Switzerland
    Document type Systematic Review
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2021.646613
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  10. Article: A new surgical method of treatment spontaneous intracranial hemorrhage.

    Du, Ning / Wang, Xinjun / Zhang, Xuyang / Xie, Jingwei / Zhou, Shaolong / Wu, Yuehui / Guo, Yongkun

    Translational neuroscience

    2021  Volume 12, Issue 1, Page(s) 145–153

    Abstract: Objective: This study aimed to determine the safety and effectiveness of DTI-assisted neuroendoscopy for treating intracranial hemorrhage (ICH).: Methods: This retrospective study included clinical data from 260 patients with spontaneous ... ...

    Abstract Objective: This study aimed to determine the safety and effectiveness of DTI-assisted neuroendoscopy for treating intracranial hemorrhage (ICH).
    Methods: This retrospective study included clinical data from 260 patients with spontaneous supratentorial ICH who received neuroendoscopic hematoma removal. Patients were separated into groups based on the surgery method they received: DTI-assisted neuroendoscopy (69 cases) and standard neuroendoscopy (191 cases). All patients were followed up for 6 months. Multivariate logistic regression analyzed the risk factors affecting the prognosis of patients. The outcomes of the two groups were compared using Kaplan-Meier survival curves.
    Results: The prognostic modified Rankin Scale (mRS) score was significantly better (
    Conclusions: The use of DTI in neuroendoscopic hematoma removal can significantly improve neurological function outcomes in patients, but it does not significantly affect the mortality of patients.
    Language English
    Publishing date 2021-04-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2581219-1
    ISSN 2081-6936 ; 2081-3856
    ISSN (online) 2081-6936
    ISSN 2081-3856
    DOI 10.1515/tnsci-2020-0164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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