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  1. AU="Wulf, Sarah"
  2. AU="DeVito, Michael"
  3. AU="Fehérvári, Lajos"
  4. AU="Sompa, Sagarika Adhikary"
  5. AU="Ladkany, Rand"
  6. AU=Jain Gaurav
  7. AU="Maldonado, Alejandra"
  8. AU="Junichi Takagi"
  9. AU="Aitor Rodriguez-Casanova"
  10. AU="Wimpenny, Claire"
  11. AU=Gao W J
  12. AU="Suarez-Almazor, Maria E"
  13. AU="Barciszewski, Jakub"
  14. AU=Madhusoodanan Jyoti
  15. AU="Korbecki, Jan"

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  1. Artikel ; Online: Implications of Overturning Roe v Wade on Abortion Training in US Family Medicine Residency Programs.

    Wulf, Sarah / Vinekar, Kavita / Dehlendorf, Christine / Srinivasulu, Silpa / Steinauer, Jody / Carvajal, Diana N

    Annals of family medicine

    2023  Band 21, Heft 6, Seite(n) 545–548

    Abstract: In June 2022, the US Supreme Court ... ...

    Abstract In June 2022, the US Supreme Court overturned
    Mesh-Begriff(e) Pregnancy ; Female ; Humans ; United States ; Internship and Residency ; Family Practice ; Abortion, Induced ; Inservice Training
    Sprache Englisch
    Erscheinungsdatum 2023-11-27
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2171425-3
    ISSN 1544-1717 ; 1544-1709
    ISSN (online) 1544-1717
    ISSN 1544-1709
    DOI 10.1370/afm.3042
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Exploring the impact of mifepristone's risk evaluation and mitigation strategy (REMS) on the integration of medication abortion into US family medicine primary care clinics✰,✰✰.

    Razon, Na'amah / Wulf, Sarah / Perez, Citlali / McNeil, Sarah / Maldonado, Lisa / Fields, Alison Byrne / Carvajal, Diana / Logan, Rachel / Dehlendorf, Christine

    Contraception

    2022  Band 109, Seite(n) 19–24

    Abstract: Objectives: In 2000, the United States' Food and Drug Administration (FDA) approved mifepristone for medication abortion. In this article, we explore how the Risk Evaluation and Mitigation Strategy (REMS) criteria for mifepristone specifically impede ... ...

    Abstract Objectives: In 2000, the United States' Food and Drug Administration (FDA) approved mifepristone for medication abortion. In this article, we explore how the Risk Evaluation and Mitigation Strategy (REMS) criteria for mifepristone specifically impede family physicians' ability to provide medication abortion in primary care settings.
    Study design: We conducted 56 qualitative interviews with a national sample of family physicians across the US who were not opposed to abortion. We examined how the REMS criteria for mifepristone impact family physicians' ability to provide medication abortion.
    Results: Of the 56 interviews conducted, 23 participants (41%) raised the REMS criteria as a barrier to providing medication abortion in primary care. These participants reported the REMS added a layer of bureaucratic complexity that made it difficult for family physicians to navigate, even when trained, to provide abortion care. These family physicians described 2 predominant ways the REMS impede their ability to provide medication abortion: (1) The REMS require substantial involvement of clinic administration, who can be unsupportive; (2) The complexity of navigating the REMS results in physicians and clinic administration in primary care viewing medication abortion as not worth the effort, since it is only a small component of services offered in primary care.
    Conclusion: Removing the REMS could simplify integration of medication abortion into primary care, which could meet patient preferences, improve access, and reduce abortion stigma. The FDA's revised REMS criteria may ease administrative burden but will likely maintain key barriers to integrating medication abortion into family physicians' practice.
    Implications: Our study highlights that the REMS criteria are barriers to family physicians' ability to integrate medication abortion into their primary care practices. The FDA's removal of in person dispensing criteria may provide some impetus for trained family physicians to integrate medication abortion into their scope of practice but the revised REMS criteria maintain key barriers to broader adoption.
    Mesh-Begriff(e) Abortion, Induced ; Abortion, Spontaneous ; Family Practice ; Female ; Humans ; Mifepristone ; Pregnancy ; Primary Health Care ; Risk Evaluation and Mitigation ; United States
    Chemische Substanzen Mifepristone (320T6RNW1F)
    Sprache Englisch
    Erscheinungsdatum 2022-02-04
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80106-9
    ISSN 1879-0518 ; 0010-7824
    ISSN (online) 1879-0518
    ISSN 0010-7824
    DOI 10.1016/j.contraception.2022.01.017
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: "They Go Hand in Hand": Perspectives on the Relationship Between the Core Values of Family Medicine and Abortion Provision Among Family Physicians Who Do Not Oppose Abortion.

    Wulf, Sarah / Carvajal, Diana N / Razon, Na'amah / Perez, Citlali / McNeil, Sarah / Maldonado, Lisa / Fields, Alison Byrne / Silverstein, Ilana / Dehlendorf, Christine

    Journal of the American Board of Family Medicine : JABFM

    2023  Band 36, Heft 4, Seite(n) 583–590

    Abstract: Introduction: Most family physicians do not provide abortion care, despite an apparent alignment between the defined values of family medicine and provision of abortion in primary care. This study seeks to understand how family physicians themselves ... ...

    Abstract Introduction: Most family physicians do not provide abortion care, despite an apparent alignment between the defined values of family medicine and provision of abortion in primary care. This study seeks to understand how family physicians themselves perceive the relationship between their specialty's values and abortion provision.
    Methods: We conducted in-depth interviews in 2019 with 56 family physicians who do not oppose abortion in the United States. We employed a deductive-inductive content analysis approach with memos to identify key themes. This analysis focuses on participants' beliefs in the core values of family medicine and how those values relate to abortion in family medicine.
    Results: Participants identified and described six values of the specialty they prioritized, which included relationships, care across the lifespan, whole-person care, nonjudgmental care, meeting community needs, and social justice. Family physicians in the study overwhelmingly believed that abortion aligned with family medicine values, regardless of whether they themselves provided abortion care.
    Conclusions: Providing abortion care in primary care settings gives family physicians an opportunity to provide comprehensive care while improving access to meet community needs. As abortion care becomes increasingly restricted in the United States, family physicians can manifest the values of family medicine through integrating abortion care into their practices in states where abortion remains legal.
    Mesh-Begriff(e) Pregnancy ; Female ; Humans ; United States ; Family Practice ; Physicians, Family ; Abortion, Induced
    Sprache Englisch
    Erscheinungsdatum 2023-06-15
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2239939-2
    ISSN 1558-7118 ; 1557-2625
    ISSN (online) 1558-7118
    ISSN 1557-2625
    DOI 10.3122/jabfm.2022.220301R2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Buch ; Dissertation / Habilitation: Application of new reconstruction strategies to enhance the interpretable resolution in 3D electron microscopy

    Wulf, Sarah Elise Freyja

    studies of rigor and ADP binding complexes of actin and myosin V

    2014  

    Verfasserangabe [by Sarah Elise Freyja Wulf]
    Sprache Englisch
    Umfang VI, 183 S., Ill., graph. Darst.
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Univ., Diss.--Heidelberg, 2014
    Datenquelle Katalog der Technische Informationsbibliothek Hannover

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  5. Artikel: End-stage renal disease: unmet treatment needs across the globe

    Wulf, Sarah K / Naghavi, Mohsen

    lancet. 2013 June 17, v. 381S2

    2013  

    Abstract: BACKGROUND: Chronic kidney disease (CKD) is a major health and economic burden globally. This progressive disease is treatable by dialysis and kidney transplantation when the kidneys reach CKD stage 5 or end-stage renal disease (ESRD), but these two ... ...

    Abstract BACKGROUND: Chronic kidney disease (CKD) is a major health and economic burden globally. This progressive disease is treatable by dialysis and kidney transplantation when the kidneys reach CKD stage 5 or end-stage renal disease (ESRD), but these two interventions are very expensive and often unavailable in low-resource settings. The aim of this study is to provide a country-level comparison of dialysis rates, transplantation rates, and untreated CKD stage 5 in order to identify countries and regions with large disparities and unmet treatment need for ESRD. METHODS: We used a negative binomial Bayesian meta-regression tool to analyse data collected from systematic literature reviews and national renal replacement registries in order to estimate incidence and prevalence of ESRD on dialysis, ESRD with kidney transplantation, and untreated ESRD for 187 countries by year, age, and sex. We then assessed ratios of treated to untreated ESRD to identify countries with extreme unmet need for kidney disease treatment. FINDINGS: Both dialysis and kidney transplantation rates have increased considerably since 1990, but there are still significant disparities both within and across countries. Globally in 2010, the proportion of CKD stage 5 and ESRD patients who received dialysis or had kidney transplantation was only 58·9% (95% CI 55·6–61·0), ranging from less than 2% in most of sub-Saharan Africa to over 70% in high-income North America, high-income Asia Pacific, and east Asia. INTERPRETATION: These estimates are a crucial factor to help to inform public health policy decisions and the nephrology community, especially in countries previously lacking such estimates. There is an urgent need for better monitoring and data collection of CKD stage 5 in order to better prepare health systems for ESRD treatment needs. FUNDING: Bill & Melinda Gates Foundation. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders.
    Schlagwörter data collection ; dialysis ; health policy ; hemodialysis ; kidney diseases ; kidney transplant ; kidneys ; monitoring ; patients ; East Asia ; North America ; Sub-Saharan Africa
    Sprache Englisch
    Erscheinungsverlauf 2013-0617
    Umfang p. S150.
    Erscheinungsort Elsevier Ltd.
    Dokumenttyp Artikel
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(13)61404-X
    Datenquelle NAL Katalog (AGRICOLA)

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  6. Artikel ; Online: Beyond same-day long-acting reversible contraceptive access: a person-centered framework for advancing high-quality, equitable contraceptive care.

    Holt, Kelsey / Reed, Reiley / Crear-Perry, Joia / Scott, Cherisse / Wulf, Sarah / Dehlendorf, Christine

    American journal of obstetrics and gynecology

    2019  Band 222, Heft 4S, Seite(n) S878.e1–S878.e6

    Abstract: In the last decade-plus, there has been growing enthusiasm for long-acting reversible contraceptive methods as the solution to unintended pregnancy in the United States. Contraceptive access efforts have primarily focused on addressing provider and ... ...

    Abstract In the last decade-plus, there has been growing enthusiasm for long-acting reversible contraceptive methods as the solution to unintended pregnancy in the United States. Contraceptive access efforts have primarily focused on addressing provider and policy barriers to long-acting reversible contraception and have promoted long-acting reversible contraception as first-line methods through marketing and tiered-effectiveness counseling. A next generation of contraceptive access efforts has the opportunity to move beyond this siloed focus on long-acting reversible contraception toward a focus on equity and person-centeredness. Here we define a new framework for increasing equitable access to high-quality, person-centered contraceptive care that includes programmatic elements necessary to provide information and services to address the barriers to accessing quality care, organized into a four-part continuum. The continuum is contextualized within structural, systematic, and social factors that influence experience of contraceptive care. We aim to provide a practical framework for researchers, program implementers, and policy makers to develop and evaluate efforts to improve equitable access to and quality of contraceptive care. Initiatives can intentionally be cognizant of broader structural and social factors that will influence their success and the likelihood of negative unintended consequences for marginalized groups and thus deliberately work to design programs that meet all people's contraceptive needs and support reproductive autonomy.
    Mesh-Begriff(e) Coercion ; Contraception/methods ; Decision Making, Shared ; Family Planning Services ; Health Equity ; Health Services Accessibility ; Humans ; Long-Acting Reversible Contraception ; Patient Participation ; Patient Preference ; Patient-Centered Care ; Personal Autonomy ; Quality of Health Care
    Sprache Englisch
    Erscheinungsdatum 2019-12-03
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1016/j.ajog.2019.11.1279
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Family Physicians' Barriers and Facilitators in Incorporating Medication Abortion.

    Razon, Na'amah / Wulf, Sarah / Perez, Citlali / McNeil, Sarah / Maldonado, Lisa / Fields, Alison Byrne / Holt, Kelsey / Fox, Edith / Silverstein, Ilana / Dehlendorf, Christine

    Journal of the American Board of Family Medicine : JABFM

    2022  Band 35, Heft 3, Seite(n) 579–587

    Abstract: Purpose: Medication abortion (MAB) provision by family physicians has the potential to expand abortion access. However, there are documented individual and structural barriers to provision. This study investigates how family physicians in the United ... ...

    Abstract Purpose: Medication abortion (MAB) provision by family physicians has the potential to expand abortion access. However, there are documented individual and structural barriers to provision. This study investigates how family physicians in the United States (US) navigate the barriers impeding abortion provision in primary care.
    Methods: We conducted a qualitative study on the experiences of US family physicians with MAB in primary care. We recruited participants at national conferences and via professional networks. This analysis focuses on the experiences of the subset of participants who expressed interest in providing MAB.
    Results: Forty-eight participants met inclusion criteria, with representation from all 4 regions of the US. Participants had diverse experiences related to abortion provision, training, and the environment in which they practice, with a third of participants working in states with hostile abortion policies. We categorized participants into 3 groups: (1) doctors who did not receive training and do not provide abortions (n = 11), (2) doctors who received training but do not provide abortions (n = 20), and (3) doctors who received training and currently provide abortions (n = 17). We found that training, administrative and community support, and internal motivation to overcome barriers help family physicians integrate MAB in primary care practices. Federal and state laws, absence of training, stigma around abortion provision, inaccurate or limited knowledge of institutional barriers, and administrative resistance all contributed to doctors excluding abortion provision from their scope of practice.
    Conclusion: Improving medication abortion provision by family physicians requires addressing the individual and system barriers family physicians encounter so they receive the education, training, and support to successfully integrate abortion care into clinical practice.
    Mesh-Begriff(e) Abortion, Induced ; Female ; Humans ; Internship and Residency ; Physicians, Family ; Pregnancy ; Qualitative Research ; United States
    Sprache Englisch
    Erscheinungsdatum 2022-05-28
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2239939-2
    ISSN 1558-7118 ; 1557-2625
    ISSN (online) 1558-7118
    ISSN 1557-2625
    DOI 10.3122/jabfm.2022.03.210266
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: What's killing mothers and what's killing women? Contextualising maternal conditions in the post-MDG era using the Global Burden of Disease (GBD) Study 2010

    Johns, Nicole E / Lozano, Rafael / Wulf, Sarah

    lancet. 2013 June 17, v. 381S2

    2013  

    Abstract: BACKGROUND: Reducing maternal mortality has been particularly prominent on the public health agenda since the establishment of Millennium Development Goal (MDG) 5 (reducing the maternal mortality ratio by two thirds). Yet maternal conditions remain a ... ...

    Abstract BACKGROUND: Reducing maternal mortality has been particularly prominent on the public health agenda since the establishment of Millennium Development Goal (MDG) 5 (reducing the maternal mortality ratio by two thirds). Yet maternal conditions remain a substantial source of mortality and morbidity in many places, and the specific causes of death and disability across countries and time have not been well understood. Moving into the post-MDG era, understanding the specific causes of death and contextualising maternal mortality into the overall health of women of reproductive age will be key for priority setting and resource allocation. We aimed to quantify maternal mortality by country, age, year, and cause, and to consider this burden in the greater context of all deaths for women of reproductive age. METHODS: We calculate overall maternal mortality using ensemble modelling on more than 4700 site-years of data, including vital registration, verbal autopsy, and maternal mortality surveillance systems. We then extract HIV-related deaths and use literature-review-based meta-analysis for causal attribution of the remainder. FINDINGS: Maternal mortality by cause differs substantially across countries and time. Maternal conditions range from first to 54th in the country-level ranking of number of deaths and first to 47th in premature years of life lost (YLLs) among women aged 15 to 49 years in 2010. Globally, they constitute 7·3% (254 682 of 3 496 480) of deaths and 7·9% (14 314 053 of 181 079 482) of YLLs among women of reproductive age. INTERPRETATION: Most countries are not on track to meet the MDG 5 target for any cause of maternal mortality. While efforts to reduce mortality and morbidity during childbirth should continue, many of the countries failing to meet targets are also failing their adult female population in several other domains of health. In the post-MDG era, efforts to improve women's health must address maternal health in conjunction with cardiovascular disease, cancer, and other diseases with substantial burden. FUNDING: Bill & Melinda Gates Foundation.
    Schlagwörter adults ; cardiovascular diseases ; childbirth ; death ; disability-adjusted life year ; meta-analysis ; models ; monitoring ; morbidity ; mortality ; mothers ; necropsy ; public health ; resource allocation ; women ; women's health
    Sprache Englisch
    Erscheinungsverlauf 2013-0617
    Umfang p. S68.
    Erscheinungsort Elsevier Ltd.
    Dokumenttyp Artikel
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(13)61322-7
    Datenquelle NAL Katalog (AGRICOLA)

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  9. Artikel: Non-fatal burden of maternal conditions: country-level results from the GBD 2010 Study

    Wulf, Sarah K / Johns, Nicole / Lozano, Rafael

    lancet. 2013 June 17, v. 381S2

    2013  

    Abstract: BACKGROUND: Maternal conditions are a major cause of global burden of disease among women of reproductive age, accounting for 4·2% of disability-adjusted life-years for this group at risk. Global progress has been observed for maternal mortality, but ... ...

    Abstract BACKGROUND: Maternal conditions are a major cause of global burden of disease among women of reproductive age, accounting for 4·2% of disability-adjusted life-years for this group at risk. Global progress has been observed for maternal mortality, but morbidity due to these causes has increased since 1990. Our objective was to quantify the burden of maternal morbidity by country, age, and cause for 1990 and 2010. METHODS: We calculated incidence and point prevalence of each cause of maternal morbidity using a negative binomial Bayesian meta-regression analysis of a total of 6586 data points obtained from systematic literature reviews of each of the following causes: haemorrhage, sepsis, hypertensive disorders of pregnancy, obstructed labour, and abortion. Once estimates of disease point prevalence were generated, we applied Global Burden of Diseases, Injuries, and Risk Factors Study 2010 disability weights to determine non-fatal burden. FINDINGS: Years lived with disability have increased globally since 1990, from 1·4 million to 1·8 million. Obstructed labour accounts for the largest proportion of this burden, 65·0% (95% CI 55·1–74·1), due largely to the burden of fistula globally. South and southeast Asia experienced the highest incident rates of maternal haemorrhage, 353 and 214 cases per 1000 livebirths, respectively. Sub-Saharan Africa and south and southeast Asia all had rates of sepsis higher than 12 per 1000 livebirths, with south Asia rates exceeding 40 per 1000 live births. Over one-fourth of the estimated 43 million cases of spontaneous and induced abortion globally occur in east Asia. INTERPRETATION: There is a large burden due to maternal conditions globally, and this burden varies considerably across countries and regions. These results can be used to inform policy and intervention strategies at the national level in order to improve maternal health. FUNDING: Bill & Melinda Gates Foundation. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders.
    Schlagwörter disability weights ; disability-adjusted life year ; fistula ; hemorrhage ; induced abortion ; issues and policy ; morbidity ; mortality ; pregnancy ; risk ; risk factors ; women ; South Asia ; South East Asia ; Sub-Saharan Africa
    Sprache Englisch
    Erscheinungsverlauf 2013-0617
    Umfang p. S149.
    Erscheinungsort Elsevier Ltd.
    Dokumenttyp Artikel
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(13)61403-8
    Datenquelle NAL Katalog (AGRICOLA)

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  10. Buch ; Online ; Dissertation / Habilitation: Application of new reconstruction strategies to enhance the interpretable resolution in 3D Electron Microscopy - Studies of Rigor and ADP binding complexes of Actin and Myosin V

    Wulf, Sarah Elise Freyja [Verfasser] / Schröder, Rasmus R. [Akademischer Betreuer]

    2014  

    Verfasserangabe Sarah Elise Freyja Wulf ; Betreuer: Rasmus R. Schröder
    Schlagwörter Biowissenschaften, Biologie ; Life Science, Biology
    Thema/Rubrik (Code) sg570
    Sprache Englisch
    Verlag Universitätsbibliothek Heidelberg
    Erscheinungsort Heidelberg
    Dokumenttyp Buch ; Online ; Dissertation / Habilitation
    Datenquelle Digitale Dissertationen im Internet

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