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  1. AU="Xavier, Alessandra Rejane Ericsson de Oliveira"
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  1. Article ; Online: NEONATAL PEMPHIGUS IN AN INFANT BORN TO A MOTHER WITH PEMPHIGUS VULGARIS: A CASE REPORT.

    Carvalho, Adriana Amaral / Santos Neto, Dinamar Amador Dos / Carvalho, Mirelle Augusta Dos Reis / Eleutério, Sabrina Jeane Prates / Xavier, Alessandra Rejane Ericsson de Oliveira

    Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo

    2018  Volume 37, Issue 1, Page(s) 130–134

    Abstract: Objective: To report on the case of a patient with neonatal pemphigus that had extensive and critical skin lesions at birth.: Case description: A newborn male with extensive vesico-bullous lesions on the anterior side of his chest and abdomen at ... ...

    Title translation PÊNFIGO NEONATAL EM FILHO DE MÃE COM PÊNFIGO VULGAR: RELATO DE CASO.
    Abstract Objective: To report on the case of a patient with neonatal pemphigus that had extensive and critical skin lesions at birth.
    Case description: A newborn male with extensive vesico-bullous lesions on the anterior side of his chest and abdomen at birth. He was admitted to the pediatric ward of a hospital for an etiological diagnosis and for treatment. Based on maternal history and a clinical evaluation, the patient was diagnosed with neonatal vulgar pemphigus. His progression was satisfactory and, in the end, he did not need pharmacological interventions.
    Comments: The cases reported in the literature and the references evaluated reveal that neonatal pemphigus is rare, but that knowledge about the disease allows for an early diagnosis to be made. This has great clinical relevance considering that the disease usually manifests itself in the form of extensive epidermal lesions, even though it is transient and benign, it does not require specific treatment, and it does not have any relation with possible future diseases.
    MeSH term(s) Adult ; Female ; Humans ; Infant, Newborn ; Infant, Newborn, Diseases/diagnosis ; Infant, Newborn, Diseases/physiopathology ; Male ; Medical History Taking ; Mothers ; Pemphigus/diagnosis ; Pemphigus/physiopathology ; Remission, Spontaneous
    Language English
    Publishing date 2018-07-26
    Publishing country Brazil
    Document type Case Reports ; Journal Article
    ZDB-ID 2560228-7
    ISSN 1984-0462 ; 1984-0462
    ISSN (online) 1984-0462
    ISSN 1984-0462
    DOI 10.1590/1984-0462/;2019;37;1;00004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Identification and characterization of methicillin-resistant Staphylococcus spp. isolated from surfaces near patients in an intensive care unit of a hospital in southeastern Brazil.

    Fernandes, Luciano Freitas / Souza, Geziella Áurea Aparecida Damasceno / Almeida, Anna Christina de / Cardoso, Léia / Xavier, Mauro Aparecido de Sousa / Pinheiro, Talles Patrick Prates / Cruz, Guilherme Henrique Santos da / Dourado, Hellen Fonseca Silva / Silva, Wender Soares / Xavier, Alessandra Rejane Ericsson de Oliveira

    Revista da Sociedade Brasileira de Medicina Tropical

    2020  Volume 53, Page(s) e20200244

    Abstract: Introduction: Contaminated hospital environments contribute to the transmission of microorganisms associated with healthcare. Contaminated surfaces handled by patients or healthcare professionals are a source of microorganism transmission by hand. ... ...

    Abstract Introduction: Contaminated hospital environments contribute to the transmission of microorganisms associated with healthcare. Contaminated surfaces handled by patients or healthcare professionals are a source of microorganism transmission by hand. Methicillin-resistant Staphylococcus bacteria are among the main agents responsible for increasing healthcare-associated infections in Brazil and worldwide.
    Methods: The objective of this study was to screen and characterize methicillin-resistant Staphylococcus spp. on surfaces near patients in an intensive care unit. Microbiological samples, collected from ten beds in an intensive care unit with five sampling sites, were inoculated into a methicillin-resistant Staphylococcus aureus chromogenic medium. MALDI-TOF and PCR analyses were used to identify the bacteria. Antimicrobial susceptibility was determined using the disk diffusion test. The presence of the mecA gene was investigated using PCR.
    Results: We observed that 44 out of the 50 sampling sites presented grown isolates in the methicillin-resistant Staphylococcus aureus medium. The incidence of isolated microorganisms on the right side rail, left side rail, tables, infusion pump keypad, and cardiac monitor were 18.8 %, 36.7 %, 10.9 %, 2.4 %, and 31 %, respectively. The 42 isolates included in this study were identified as coagulase-negative Staphylococcus. All of these microorganisms were multidrug-resistant and mecA gene-positive.
    Conclusions: This study identified the presence of methicillin-resistant coagulase-negative Staphylococcus on the beds of an intensive care unit, providing evidence for the necessity of assertive actions to decrease the risk of healthcare-associated infections at the site.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Bacterial Proteins ; Brazil ; Hospitals ; Humans ; Intensive Care Units ; Methicillin Resistance ; Methicillin-Resistant Staphylococcus aureus/genetics ; Microbial Sensitivity Tests ; Staphylococcal Infections ; Staphylococcus/genetics
    Chemical Substances Anti-Bacterial Agents ; Bacterial Proteins
    Language English
    Publishing date 2020-11-06
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0244-2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2726: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Prion protein is associated with a worse prognosis of head and neck squamous cell carcinoma.

    Santos, Eloa Mangabeira / Fraga, Carlos Alberto de Carvalho / Xavier, Alessandra Rejane Ericsson de Oliveira / Xavier, Mauro Aparecido de Souza / Souza, Marcela Gonçalves / Jesus, Sabrina Ferreira de / Paula, Alfredo Maurício Batista de / Farias, Lucyana Conceição / Santos, Sérgio Henrique Sousa / Santos, Tiago Goss / Beraldo, Flavio H / Guimarães, André Luiz Sena

    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology

    2021  Volume 50, Issue 10, Page(s) 985–994

    Abstract: Background: Head and neck squamous cell carcinoma (HNSC) etiopathogenesis remains unclear, and the biological changes with the activation of heat shock proteins (HSPs) and prion protein (PRNP) promoted by hypoxia in HNSC are undetermined. This study ... ...

    Abstract Background: Head and neck squamous cell carcinoma (HNSC) etiopathogenesis remains unclear, and the biological changes with the activation of heat shock proteins (HSPs) and prion protein (PRNP) promoted by hypoxia in HNSC are undetermined. This study investigates hypoxia's effect in lymph node metastasis by PRNP expression changes and its main partners.
    Methods: The study combined a theoretical/cell culture study with a case-control study. First, bioinformatics and cell culture were performed. A case-control study was performed in a second step by comparing HNSC patients with and without lymph node metastasis.
    Analyses: The Cancer Genome Atlas (TCGA) data source validates the theory in the global population study.
    Results: Bioinformatics analysis suggests that hypoxia-inducible factor-1α (HIF1A) is associated with HSPA4, HSP90AA1 and PRNP expression. TCGA data validate the hypothesis that higher HSP90AA1, HSPA4 and PRNP are related to metastases and low survival. Herein, the cell study demonstrated that muted PRNP did not respond to hypoxia.
    Discussion: Our results collectively provide the first evidence that PRNP promotes HNSC lymph node metastasis progression through the upregulation of HSPA4, HSP90AA1 and HIF1A. Our findings may provide a molecular basis for the promoting Role of PRNP in HNSC progression.
    MeSH term(s) Biomarkers, Tumor/genetics ; Case-Control Studies ; Head and Neck Neoplasms/genetics ; Humans ; Prion Proteins/genetics ; Prognosis ; Squamous Cell Carcinoma of Head and Neck/genetics
    Chemical Substances Biomarkers, Tumor ; Prion Proteins
    Language English
    Publishing date 2021-05-24
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1021270-x
    ISSN 1600-0714 ; 0904-2512
    ISSN (online) 1600-0714
    ISSN 0904-2512
    DOI 10.1111/jop.13188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 825: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Characterization and molecular epidemiology of

    Souza, Geziella Áurea Aparecida Damasceno / de Almeida, Anna Christina / Xavier, Mauro Aparecido de Sousa / da Silva, Lívia Mara Vitorino / Sousa, Cintya Neves / Sanglard, Demerson Arruda / Xavier, Alessandra Rejane Ericsson de Oliveira

    Veterinary world

    2019  Volume 12, Issue 12, Page(s) 1931–1939

    Abstract: Background and aim: The term ESKAPE, recognized by the WHO, is an acronym, which refers to the pathogens : Materials and methods: Sixteen microorganisms previously identified as : Results: All isolates showed phenotypic resistance to at least ... ...

    Abstract Background and aim: The term ESKAPE, recognized by the WHO, is an acronym, which refers to the pathogens
    Materials and methods: Sixteen microorganisms previously identified as
    Results: All isolates showed phenotypic resistance to at least three beta-lactams, among which was meropenem. None of the isolates tested positive for the genes
    Conclusion: In this study, we identified beta-lactams resistant
    Language English
    Publishing date 2019-12-11
    Publishing country India
    Document type Journal Article
    ZDB-ID 2456277-4
    ISSN 2231-0916 ; 0972-8988
    ISSN (online) 2231-0916
    ISSN 0972-8988
    DOI 10.14202/vetworld.2019.1931-1939
    Database MEDical Literature Analysis and Retrieval System OnLINE

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