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  1. Article: Testicular torsion in a newborn: a case report.

    Blevrakis, E / Xenaki, S / Chrysos, E

    Il Giornale di chirurgia

    2019  Volume 40, Issue 1, Page(s) 54–57

    Abstract: Discovery of an apparent scrotal mass is a non common entity in neonates. Testicular torsion is rare in newborn infants and is an urologic emergency that requires emergency surgical management. We present a rare case of testicular torsion in a neonate. ...

    Abstract Discovery of an apparent scrotal mass is a non common entity in neonates. Testicular torsion is rare in newborn infants and is an urologic emergency that requires emergency surgical management. We present a rare case of testicular torsion in a neonate.
    MeSH term(s) Early Diagnosis ; Humans ; Infant, Newborn ; Male ; Necrosis/etiology ; Necrosis/surgery ; Orchiectomy ; Orchiopexy ; Spermatic Cord/pathology ; Spermatic Cord Torsion/diagnostic imaging ; Spermatic Cord Torsion/surgery ; Testis/pathology ; Ultrasonography
    Language English
    Publishing date 2019-02-10
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 605974-0
    ISSN 1971-145X ; 0391-9005
    ISSN (online) 1971-145X
    ISSN 0391-9005
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  2. Article ; Online: Coexistance of a well differentiated liposarcoma and dedifferentiated low grade myxofibrosarcoma of the scrotum. A rare case and review of the literature.

    Xenaki, S / Panagiotakis, G / Lagoudaki, H / Tzardi, M / Chrysos, E / Petrakis, J

    Il Giornale di chirurgia

    2020  Volume 40, Issue 6, Page(s) 526–529

    Abstract: Liposarcoma is a malignant soft tissue sarcoma usually located in the thigh or the posterior peritoneum in an adult. However, the occurrence of liposarcoma, and indeed a coexistance with scrotal myxofibrosarcoma, is rare. We present an interesting case ... ...

    Abstract Liposarcoma is a malignant soft tissue sarcoma usually located in the thigh or the posterior peritoneum in an adult. However, the occurrence of liposarcoma, and indeed a coexistance with scrotal myxofibrosarcoma, is rare. We present an interesting case of a 56-year old male who presented with an inguinal hernia. During the operation a massive fibro-elastic mass located within the left scrotum was noticed which deposited the testicle upward by displacing it into a sack rather than the penis. The mass did not come into contact with the spermatic cord but alongside it the existence of the blood vessels of the mass was found. The histopathological examination revealed a well differentiated liposarcoma along with dedifferentiated low grade myxofibrosarcoma.
    MeSH term(s) Fibrosarcoma/pathology ; Fibrosarcoma/surgery ; Genital Neoplasms, Male/pathology ; Genital Neoplasms, Male/surgery ; Humans ; Liposarcoma/pathology ; Liposarcoma/surgery ; Male ; Middle Aged ; Neoplasms, Multiple Primary/pathology ; Neoplasms, Multiple Primary/surgery ; Scrotum
    Language English
    Publishing date 2020-01-30
    Publishing country Italy
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 605974-0
    ISSN 1971-145X ; 0391-9005
    ISSN (online) 1971-145X
    ISSN 0391-9005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Early Postoperative Parathormone and Calcium as Prognostic Factors for Postoperative Hypocalcemia.

    Daskalaki, Anna / Xenaki, Sofia / Lasithiotakis, Konstantinos / Chrysos, Alexandros / Kampa, Marilena / Notas, George / Chrysos, Emmanuel

    Journal of clinical medicine

    2022  Volume 11, Issue 9

    Abstract: Background: Postoperative hypocalcemia is one of the most common complications after total thyroidectomy. Parathormone (PTH) and calcium levels, measured several hours after surgery, have been suggested as valuable markers for detecting patients at risk ...

    Abstract Background: Postoperative hypocalcemia is one of the most common complications after total thyroidectomy. Parathormone (PTH) and calcium levels, measured several hours after surgery, have been suggested as valuable markers for detecting patients at risk for post-thyroidectomy hypocalcemia. We aimed to determine if early post-surgery PTH and calcium levels can be used for the early identification of patients at risk for symptomatic hypocalcemia.
    Methods: PTH and calcium were measured before surgery and at 10 min and 4 h post-thyroidectomy, in 77 patients. Performance characteristics of PTH and calcium levels and their post/pre-surgery ratios were calculated.
    Results: Four-hour calcium was a sensitive (93.75%) but not specific (67.61%) indicator of patients at risk for symptomatic hypocalcemia. The 4-h/pre-surgery PTH ratio was the most accurate (90.81%) and the most specific (94.37%) test to identify patients at risk. Serum calcium at 4-h, 4-h/pre-surgery PTH ratio, and PTH at 10 min post-surgery had the higher diagnostic odds ratios (50.86, 32.85, and 29.04, respectively). The 4-h/pre-surgery PTH ratio also had the highest (0.694) Youden's J statistic.
    Conclusions: Low serum calcium levels 4 h after thyroidectomy and the 4-h/pre-surgery PTH ratio could be valuable additions to everyday clinical practice in post-thyroidectomy patients.
    Language English
    Publishing date 2022-04-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11092389
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Correction: Daskalaki et al. Early Postoperative Parathormone and Calcium as Prognostic Factors for Postoperative Hypocalcemia.

    Daskalaki, Anna / Xenaki, Sofia / Lasithiotakis, Konstantinos / Chrysos, Alexandros / Kampa, Marilena / Notas, George / Chrysos, Emmanuel

    Journal of clinical medicine

    2022  Volume 11, Issue 24

    Abstract: In the published article [ ... ]. ...

    Abstract In the published article [...].
    Language English
    Publishing date 2022-12-08
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11247280
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Robotic D3 Partial Duodenal Resection with Primary Side-to-Side Anastomosis.

    Montorsi, Roberto Maria / Xenaki, Sofia / Festen, Sebastiaan / Fockens, Paul / Bastiaansen, Barbara A J / Daams, Freek / Busch, Olivier R / Besselink, M G

    Journal of visualized experiments : JoVE

    2023  , Issue 202

    Abstract: Duodenal stenosis is a condition that can be related to several diseases, being either intrinsic, such as neoplasm and inflammatory stenosis, or extrinsic, such as pancreatic pseudocyst, superior mesenteric artery syndrome, and foreign bodies. Current ... ...

    Abstract Duodenal stenosis is a condition that can be related to several diseases, being either intrinsic, such as neoplasm and inflammatory stenosis, or extrinsic, such as pancreatic pseudocyst, superior mesenteric artery syndrome, and foreign bodies. Current treatments range from endoscopic approaches, such as endoscopic resection and stent placement, to surgical approaches, including duodenal resection, pancreaticoduodenectomy, and gastrointestinal bypass. Minimally invasive robot-assisted surgery is gaining importance due to its potential to decrease surgical stress, intraoperative blood loss, and postoperative pain, while its instruments and 3D-vision facilitate fine dissection and intra-abdominal suturing, all leading to a reduced time to functional recovery and shorter hospital stay. We present a case of a 75-year-old female who underwent robotic D3 partial duodenal resection with primary side-to-side duodeno-jejunal anastomosis for a 5 cm adenoma with focal high-grade dysplasia.
    MeSH term(s) Female ; Humans ; Aged ; Robotic Surgical Procedures ; Duodenum/surgery ; Robotics ; Anastomosis, Surgical ; Pancreaticoduodenectomy ; Laparoscopy
    Language English
    Publishing date 2023-12-15
    Publishing country United States
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 2259946-0
    ISSN 1940-087X ; 1940-087X
    ISSN (online) 1940-087X
    ISSN 1940-087X
    DOI 10.3791/65742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Advanced Mesodermal (Müllerian) Adenosarcoma of the Ovary: Metastases to the Lungs, Mouth, and Brain.

    Daskalaki, A / Xenaki, S / Athanasakis, E / Chrysos, E / Chalkiadakis, G

    Case reports in surgery

    2015  Volume 2015, Page(s) 403431

    Abstract: Background. A malignant mixed Müllerian tumor (MMMT) is a malignant neoplasm found in the uterus, the ovaries, the fallopian tubes, and other parts of the body that contains both carcinomatous (epithelial tissue) and sarcomatous (connective tissue) ... ...

    Abstract Background. A malignant mixed Müllerian tumor (MMMT) is a malignant neoplasm found in the uterus, the ovaries, the fallopian tubes, and other parts of the body that contains both carcinomatous (epithelial tissue) and sarcomatous (connective tissue) components. Outcome of MMMTs is determined primarily by depth of invasion and stage. The metastatic background of these lesions is controversial and unknown. Case Report. A 75-year-old woman was admitted to the hospital with anorexia, weakness, and persistent coughing. The imaging exams revealed a solid, promiscuous lesion of 16 × 14 cm in dimensions located into the small pelvis, surrounding the uterus and the ovaries. The patient underwent exploratory laparotomy. The mass was removed and the histological examination of the specimen revealed an advanced mesodermal adenocarcinoma of the ovary (MMMT). Nine days after the operation the patient presented with metastatic lesions in the mouth as well as the lungs. Within a month after the discharge from the hospital metastatic lesions of the MMMT were also depicted in the CT brain scan. Conclusion. Despite the fact that sarcomas have a long-term metastatic potential, to our knowledge this is the first case of Müllerian adenosarcoma presenting with such extraperitoneal metastases.
    Language English
    Publishing date 2015-12-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2657697-1
    ISSN 2090-6919 ; 2090-6900
    ISSN (online) 2090-6919
    ISSN 2090-6900
    DOI 10.1155/2015/403431
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  7. Article: Well-promising outcomes with vacuum-assisted closure in an infected wound following laparotomy: A case report.

    Daskalaki, A / Xenaki, S / Venianaki, M / Topalidou, A / Athanasakis, E / Chrysos, E / Chalkiadakis, G

    Annals of medicine and surgery (2012)

    2016  Volume 10, Page(s) 73–76

    Abstract: Introducation: Negative pressure wound therapy (NPWT) represents an alternative method to optimize conditions for wound healing. Delayed wound closure is a significant health problem, which is directly associated with pain and suffering from patient's ... ...

    Abstract Introducation: Negative pressure wound therapy (NPWT) represents an alternative method to optimize conditions for wound healing. Delayed wound closure is a significant health problem, which is directly associated with pain and suffering from patient's aspect, as well with social and financial burden.
    Presentation of case: We report a case of vacuum-assisted wound therapy with hypertonic solution distillation and continuous negative pressure application, in an infected wound after laparotomy for incisional hernia reconstruction with mesh placement. Negative pressure was initiated at the wound margins after failure of conventional treatment with great outcomes, achieving a total closure of the incision within two weeks.
    Discussion: Each wound has particular characteristics which must be managed. Vacuum assisted closure (VAC) with continuous negative pressure and simultaneous wound instillation and cleanse can provide optimum results, reducing the cavity volume, by newly produced granulated tissue.
    Conclusion: The simultaneous use of instillation and constant pressure seemed to be superior in comparison with NPWT alone. Compared to conventional methods, the use of VAC ends to better outcomes, in cases of infected wounds following laparotomy.
    Language English
    Publishing date 2016-08-02
    Publishing country England
    Document type Case Reports
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1016/j.amsu.2016.07.027
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  8. Article: Newly recognized extratumoral features of colorectal cancer challenge the current tumor-node-metastasis staging system.

    Athanasakis, Elias / Xenaki, Sofia / Venianaki, Maria / Chalkiadakis, George / Chrysos, Emmanuel

    Annals of gastroenterology

    2018  Volume 31, Issue 5, Page(s) 525–534

    Abstract: One of the most common malignant tumors in humans, colorectal cancer has been extensively studied during the past few decades. Staging colorectal cancer allows clinicians to obtain precise prognostic information and apply specific treatment procedures. ... ...

    Abstract One of the most common malignant tumors in humans, colorectal cancer has been extensively studied during the past few decades. Staging colorectal cancer allows clinicians to obtain precise prognostic information and apply specific treatment procedures. Apart from remote metastases, the depth of tumor infiltration and lymph node involvement have traditionally been recognized as the most important factors predicting outcome. Variations in the molecular signature of colorectal cancer have also revealed differences in phenotypic aggressiveness and therapeutic response rates. This article presents a review of the extratumoral environment in colorectal surgery.
    Language English
    Publishing date 2018-06-19
    Publishing country Greece
    Document type Journal Article ; Review
    ZDB-ID 2032850-3
    ISSN 1108-7471
    ISSN 1108-7471
    DOI 10.20524/aog.2018.0284
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  9. Article: A case of solitary rectal diverticulum presenting with a large retrorectal abscess.

    Gorgoraptis, Stefanos / Xenaki, Sofia / Athanasakis, Elias / Daskalaki, Anna / Lasithiotakis, Konstantinos / Chrysou, Evangelia / Chrysos, Emmanuel

    Annals of medicine and surgery (2012)

    2019  Volume 49, Page(s) 57–60

    Abstract: Colonic diverticular disease is a common condition, affecting 50% of the population aged above 80. In contrast, rectal diverticular disease is a rare condition with very few cases reported, while symptomatic rectal diverticular disease is even rarer. We ... ...

    Abstract Colonic diverticular disease is a common condition, affecting 50% of the population aged above 80. In contrast, rectal diverticular disease is a rare condition with very few cases reported, while symptomatic rectal diverticular disease is even rarer. We present a case of a symptomatic large rectal diverticulum presenting with a retrorectal abscess. A 49-year-old Caucasian female was brought to the emergency department complaining of abdominal pain and weakness in the lower limbs. She was found to have obstructive uropathy and unilateral sciatic neuropathy. She rapidly developed acute abdomen and emergency laparotomy revealed a giant purulent rectal diverticulum. The patient underwent exploratory laparotomy and a loop colostomy was made to decompress the colon.
    Language English
    Publishing date 2019-11-27
    Publishing country England
    Document type Case Reports
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1016/j.amsu.2019.11.015
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  10. Article ; Online: A Comparison of Two Preoperative Frailty Models in Predicting Postoperative Outcomes in Geriatric General Surgical Patients.

    Andreou, Alexandros / Lasithiotakis, Konstantinos / Venianaki, Maria / Xenaki, Sofia / Chlouverakis, Grigorios / Petrakis, Ioannis / Chalkiadakis, Georgios

    World journal of surgery

    2018  Volume 42, Issue 12, Page(s) 3897–3902

    Abstract: Background: Frailty in a surgical geriatric population may identify patients at increased risk of complications. However, the optimal method to diagnose it remains to be identified. This study aims to compare two common frailty models and assess their ... ...

    Abstract Background: Frailty in a surgical geriatric population may identify patients at increased risk of complications. However, the optimal method to diagnose it remains to be identified. This study aims to compare two common frailty models and assess their association with postoperative adverse outcomes in elderly patients undergoing general surgical procedures.
    Methods: Prospective study including 298 patients age 65 years or older undergoing elective general surgical operations in a tertiary hospital. Frailty phenotype (FP) was classified using a validated scale which included weight loss, weakness, exhaustion, slowed walking speed and low physical activity. A preoperative comprehensive geriatric assessment (CGA) was performed including managing daily activities (ADL), instrumental ADL, cognitive status, comorbidities, polypharmacy and nutritional status. Main outcomes measures were postoperative complications and length of stay.
    Results: There were 135 (46%), 114 (38%) and 46 (15%) minor/intermediate, major and major + procedures, respectively. The agreement between the FP and CGA was moderate (kappa index: 0.45). FP was significantly associated with postoperative complications with an odds ratio (OR) of 2.3, (95% confidence interval 1.4-3.8, p < 0.01). The association of CGA with postoperative complications did not reach statistical significance (p = 0.07). Postoperative hospital stay was significantly longer in both CGA frailty (p < 0.001) and FP (p = 0.001) groups compared to the fit population. In the multivariate analysis adjusted for ASA and POSSUM category, FP retained its significance as a predictor of postoperative complications (OR: 1.9, 95% CI 1.03-3.3, p = 0.038).
    Conclusions: FP was associated more consistently than CGA with adverse postoperative outcomes in elderly patients undergoing general surgical procedures.
    MeSH term(s) Aged ; Aged, 80 and over ; Elective Surgical Procedures/adverse effects ; Female ; Frailty/complications ; Frailty/diagnosis ; Geriatric Assessment ; Humans ; Length of Stay ; Male ; Postoperative Complications/etiology ; Postoperative Period ; Prospective Studies ; Surgical Procedures, Operative/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2018-04-21
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 224043-9
    ISSN 1432-2323 ; 0364-2313
    ISSN (online) 1432-2323
    ISSN 0364-2313
    DOI 10.1007/s00268-018-4734-3
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