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  1. Article ; Online: Editorial for "Intertumoral Heterogeneity Based on MRI Radiomics Features Estimates Recurrence in Hepatocellular Carcinoma".

    Li, Binrong / Yu, Yaoyao / Xia, Tianyi

    Journal of magnetic resonance imaging : JMRI

    2024  

    Language English
    Publishing date 2024-05-07
    Publishing country United States
    Document type Editorial
    ZDB-ID 1146614-5
    ISSN 1522-2586 ; 1053-1807
    ISSN (online) 1522-2586
    ISSN 1053-1807
    DOI 10.1002/jmri.29433
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3648: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 236: Show issues

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  2. Article: Quality of Low-Allergy Wheat ('O-Free') Flour and Optimization of Its Bread-Baking Performance.

    Xia, Tianyi / Kim, Kyeonghoon / Kweon, Meera

    Foods (Basel, Switzerland)

    2022  Volume 11, Issue 21

    Abstract: This study explored the quality of hypoallergenic wheat ('O-free') developed in Korea and optimized the basic ingredients and processing conditions for making 'O-free' bread using response surface methodology. Water and yeast amounts and mixing and ... ...

    Abstract This study explored the quality of hypoallergenic wheat ('O-free') developed in Korea and optimized the basic ingredients and processing conditions for making 'O-free' bread using response surface methodology. Water and yeast amounts and mixing and fermentation times were selected as factors, and each factor's tested range was set by a central composite design using Design Experts: water 52-60 g, yeast 1.5-4.5 g, mixing time 2.5-5 min, and fermentation time 50-70 min. Bread height, volume, and firmness were analyzed to determine bread quality. Flour quality analysis showed that 'O-free' flour's gluten strength was weak. 'O-free' flour exhibited inferior bread-making performance compared to representative bread flour. Water and yeast amounts and mixing time, except for fermentation time, affected bread quality significantly. The interaction between yeast and fermentation also affected bread quality significantly. The optimized condition for making bread using 'O-free' flour is 60 g of water, 2.6 g of yeast, 2.5 min of mixing time, and 70.0 min of fermentation time. In conclusion, 'O-free' flour with the changed gluten composition showed poor gluten strength and bread-making performance. However, modifying the formulation of the basic ingredients and processing conditions could significantly improve the production of high-quality hypoallergenic bread.
    Language English
    Publishing date 2022-10-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods11213399
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Vapor-deposited environmental-friendly bilayer coatings with synergistic anti-corrosion effect for electronic device protection

    Xia, Tianyi / Liu, Wenna / Ye, Yumin

    Journal of materials science. 2022 May, v. 57, no. 17

    2022  

    Abstract: Electronic devices working under harsh environments require protective polymer coatings that can resist the corrosion of their metallic components. Solvent-based polymer coating methods, however, are failing to meet the increasing demand by the trending ... ...

    Abstract Electronic devices working under harsh environments require protective polymer coatings that can resist the corrosion of their metallic components. Solvent-based polymer coating methods, however, are failing to meet the increasing demand by the trending miniaturization and high integration of devices. Here, we present an ultrathin bilayer conformal coating with excellent protection capability fabricated via a solvent-free initiated chemical vapor deposition method. The bilayer coating consists of a bottom barrier layer crosslinked through urea linkages and a short-fluorinated hydrophobic surface layer anchored by aromatic crosslinkers. The hydrophobic surface resists the adhesion of water and corrosive species while the barrier layer further inhibits their penetration. As a result, the bilayer coating exhibits superior anti-corrosion performance compared to single-layered coatings with a more than 10³-fold decrease in corrosion rate than bare copper and protection efficiency higher than 99.9%. Using an LED circuit board as a model device, the bilayer coating can be conformally deposited on different parts of the device. The bilayer-coated device endured 24 h working underwater, whereas device spray-coated with conventional polyurethane resin coating failed after 550 min, suggesting promising practical applications of the reported method in the protection of various electronic devices.
    Keywords adhesion ; copper ; corrosion ; electronic equipment ; hydrophobicity ; polyurethanes ; urea ; vapors
    Language English
    Dates of publication 2022-05
    Size p. 8314-8328.
    Publishing place Springer US
    Document type Article
    ZDB-ID 2015305-3
    ISSN 1573-4803 ; 0022-2461
    ISSN (online) 1573-4803
    ISSN 0022-2461
    DOI 10.1007/s10853-022-07181-0
    Database NAL-Catalogue (AGRICOLA)

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  4. Book ; Online: When SAM Meets Medical Images

    Hu, Chuanfei / Xia, Tianyi / Ju, Shenghong / Li, Xinde

    An Investigation of Segment Anything Model (SAM) on Multi-phase Liver Tumor Segmentation

    2023  

    Abstract: Learning to segmentation without large-scale samples is an inherent capability of human. Recently, Segment Anything Model (SAM) performs the significant zero-shot image segmentation, attracting considerable attention from the computer vision community. ... ...

    Abstract Learning to segmentation without large-scale samples is an inherent capability of human. Recently, Segment Anything Model (SAM) performs the significant zero-shot image segmentation, attracting considerable attention from the computer vision community. Here, we investigate the capability of SAM for medical image analysis, especially for multi-phase liver tumor segmentation (MPLiTS), in terms of prompts, data resolution, phases. Experimental results demonstrate that there might be a large gap between SAM and expected performance. Fortunately, the qualitative results show that SAM is a powerful annotation tool for the community of interactive medical image segmentation.

    Comment: Preliminary investigation
    Keywords Electrical Engineering and Systems Science - Image and Video Processing ; Computer Science - Computer Vision and Pattern Recognition
    Publishing date 2023-04-17
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Association between Liver MRI Proton Density Fat Fraction and Liver Disease Risk.

    Xia, Tianyi / Du, Mulong / Li, Huiqin / Wang, Yuancheng / Zha, Junhao / Wu, Tong / Ju, Shenghong

    Radiology

    2023  Volume 309, Issue 1, Page(s) e231007

    Abstract: Background A better understanding of the association between liver MRI proton density fat fraction (PDFF) and liver diseases might support the clinical implementation of MRI PDFF. Purpose To quantify the genetically predicted causal effect of liver MRI ... ...

    Abstract Background A better understanding of the association between liver MRI proton density fat fraction (PDFF) and liver diseases might support the clinical implementation of MRI PDFF. Purpose To quantify the genetically predicted causal effect of liver MRI PDFF on liver disease risk. Materials and Methods This population-based prospective observational study used summary-level data mainly from the UK Biobank and FinnGen. Mendelian randomization analysis was conducted using the inverse variance-weighted method to explore the causal association between genetically predicted liver MRI PDFF and liver disease risk with Bonferroni correction. The individual-level data were downloaded between August and December 2020 from the UK Biobank. Logistic regression analysis was performed to validate the association between liver MRI PDFF polygenic risk score and liver disease risk. Mediation analyses were performed using multivariable mendelian randomization. Results Summary-level and individual-level data were obtained from 32 858 participants and 378 436 participants (mean age, 57 years ± 8 [SD]; 203 108 female participants), respectively. Genetically predicted high liver MRI PDFF was associated with increased risks of malignant liver neoplasm (odds ratio [OR], 4.5;
    MeSH term(s) Female ; Humans ; Middle Aged ; Diabetes Mellitus, Type 2/pathology ; Liver/diagnostic imaging ; Liver/pathology ; Liver Cirrhosis/pathology ; Magnetic Resonance Imaging/methods ; Non-alcoholic Fatty Liver Disease/diagnostic imaging ; Non-alcoholic Fatty Liver Disease/genetics ; Non-alcoholic Fatty Liver Disease/pathology ; Male
    Language English
    Publishing date 2023-10-24
    Publishing country United States
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.231007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.106: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Erratum for: Association between Liver MRI Proton Density Fat Fraction and Liver Disease Risk.

    Xia, Tianyi / Du, Mulong / Li, Huiqin / Wang, Yuancheng / Zha, Junhao / Wu, Tong / Ju, Shenghong

    Radiology

    2023  Volume 309, Issue 2, Page(s) e239027

    Language English
    Publishing date 2023-11-28
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.239027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.106: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  7. Article ; Online: Small Solitary Ground-Glass Nodule on CT as an Initial Manifestation of Coronavirus Disease 2019 (COVID-19) Pneumonia.

    Xia, Tianyi / Li, Jiawei / Gao, Jiao / Xu, Xunhua

    Korean journal of radiology

    2020  Volume 21, Issue 5, Page(s) 545–549

    Abstract: The 2019 novel coronavirus (2019-nCoV) outbreak in Wuhan, Hubei Province, China in 2019 led to large numbers of people being infected and developing atypical pneumonia (coronavirus disease 2019, COVID-19). Typical imaging manifestations of patients ... ...

    Abstract The 2019 novel coronavirus (2019-nCoV) outbreak in Wuhan, Hubei Province, China in 2019 led to large numbers of people being infected and developing atypical pneumonia (coronavirus disease 2019, COVID-19). Typical imaging manifestations of patients infected with 2019-nCoV has been reported, but we encountered an atypical radiological manifestation on baseline computed tomography (CT) images in three patients from Wuhan, China infected with the 2019-nCoV. Surprisingly, the only similar CT finding was a solitary sub-centimeter ground-glass nodule adjacent to bronchovascular bundles, which could be easily overlooked. In addition, the follow-up images in these patients showed how COVID-19 pneumonia evolved from these small nodules. The radiologic manifestation of the three cases will expand contemporary understanding of COVID-19.
    MeSH term(s) Adult ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; China ; Clinical Laboratory Techniques ; Coronavirus ; Coronavirus Infections/diagnosis ; Coronavirus Infections/diagnostic imaging ; Diagnostic Tests, Routine ; Female ; Humans ; Lung/diagnostic imaging ; Lung/pathology ; Pandemics ; Pneumonia, Viral/diagnostic imaging ; SARS-CoV-2 ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-05-05
    Publishing country Korea (South)
    Document type Case Reports ; Journal Article
    ZDB-ID 2046981-0
    ISSN 2005-8330 ; 1229-6929
    ISSN (online) 2005-8330
    ISSN 1229-6929
    DOI 10.3348/kjr.2020.0240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5591: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Bisphenol A Promotes the Progression of Colon Cancer Through Dual-Targeting of NADPH Oxidase and Mitochondrial Electron-Transport Chain to Produce ROS and Activating HIF-1α/VEGF/PI3K/AKT Axis.

    Xia, Tianyi / Guo, Junnan / Zhang, Bomiao / Song, Chengxin / Zhao, Qunye / Cui, Binbin / Liu, Yanlong

    Frontiers in endocrinology

    2022  Volume 13, Page(s) 933051

    Abstract: Bisphenol A (BPA) is a high-production-volume industrial chemical. Despite recent research conducted on its carcinogenicity, its role in the development of colon cancer (CC) has been rarely studied. This study aims to evaluate the effects of BPA on the ... ...

    Abstract Bisphenol A (BPA) is a high-production-volume industrial chemical. Despite recent research conducted on its carcinogenicity, its role in the development of colon cancer (CC) has been rarely studied. This study aims to evaluate the effects of BPA on the migration and invasion of CC cells. First, we clinically verified that patients with CC exhibit higher serum BPA level than healthy donors. Subsequently, different CC cell lines were exposed to a series of BPA concentrations, and the migration and invasion of cells were detected by the wound healing test and transwell assay. Finally, N-acetyl-L-cysteine (NAC) and siHIF-1α intervention was used to explore the effects of ROS and HIF-1α on cell migration and invasion, respectively. The results demonstrated that the occurrence of BPA-induced migration and invasion were dependent on the dose and time and was most pronounced in DLD1 cells. ROS production was jointly driven by NADPH oxidase (NOX) and mitochondrial electron-transport chain (ETC). Furthermore, the intervention of NAC and siHIF-1α blocked the HIF-1α/VEGF/PI3K/AKT axis and inhibited cell migration and invasion. In conclusion, our results suggest that BPA exposure promotes the excessive production of ROS induced by NOX and ETC, which in turn activates the HIF-1α/VEGF/PI3K/AKT axis to promote the migration and invasion of CC cells. This study provides new insights into the carcinogenic effects of BPA on CC and warns people to pay attention to environmental pollution and the harm caused to human health by low-dose BPA.
    MeSH term(s) Benzhydryl Compounds ; Colonic Neoplasms/chemically induced ; Electrons ; Humans ; NADPH Oxidases/metabolism ; NADPH Oxidases/pharmacology ; Phenols ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction/physiology ; Vascular Endothelial Growth Factor A/metabolism
    Chemical Substances Benzhydryl Compounds ; Phenols ; Reactive Oxygen Species ; Vascular Endothelial Growth Factor A ; NADPH Oxidases (EC 1.6.3.-) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1) ; bisphenol A (MLT3645I99)
    Language English
    Publishing date 2022-07-04
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2022.933051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Computed Tomography Imaging-Based Radiogenomics Analysis Reveals Hypoxia Patterns and Immunological Characteristics in Ovarian Cancer.

    Feng, Songwei / Xia, Tianyi / Ge, Yu / Zhang, Ke / Ji, Xuan / Luo, Shanhui / Shen, Yang

    Frontiers in immunology

    2022  Volume 13, Page(s) 868067

    Abstract: Purpose: The hypoxic microenvironment is involved in the tumorigenesis of ovarian cancer (OC). Therefore, we aim to develop a non-invasive radiogenomics approach to identify a hypoxia pattern with potential application in patient prognostication.: ... ...

    Abstract Purpose: The hypoxic microenvironment is involved in the tumorigenesis of ovarian cancer (OC). Therefore, we aim to develop a non-invasive radiogenomics approach to identify a hypoxia pattern with potential application in patient prognostication.
    Methods: Specific hypoxia-related genes (sHRGs) were identified based on RNA-seq of OC cell lines cultured with different oxygen conditions. Meanwhile, multiple hypoxia-related subtypes were identified by unsupervised consensus analysis and LASSO-Cox regression analysis. Subsequently, diversified bioinformatics algorithms were used to explore the immune microenvironment, prognosis, biological pathway alteration, and drug sensitivity among different subtypes. Finally, optimal radiogenomics biomarkers for predicting the risk status of patients were developed by machine learning algorithms.
    Results: One hundred forty sHRGs and three types of hypoxia-related subtypes were identified. Among them, hypoxia-cluster-B, gene-cluster-B, and high-risk subtypes had poor survival outcomes. The subtypes were closely related to each other, and hypoxia-cluster-B and gene-cluster-B had higher hypoxia risk scores. Notably, the low-risk subtype had an active immune microenvironment and may benefit from immunotherapy. Finally, a four-feature radiogenomics model was constructed to reveal hypoxia risk status, and the model achieved area under the curve (AUC) values of 0.900 and 0.703 for the training and testing cohorts, respectively.
    Conclusion: As a non-invasive approach, computed tomography-based radiogenomics biomarkers may enable the pretreatment prediction of the hypoxia pattern, prognosis, therapeutic effect, and immune microenvironment in patients with OC.
    MeSH term(s) Carcinoma, Ovarian Epithelial ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Hypoxia/genetics ; Hypoxia/metabolism ; Ovarian Neoplasms/diagnostic imaging ; Ovarian Neoplasms/genetics ; Prognosis ; Tomography, X-Ray Computed ; Tumor Microenvironment/genetics
    Language English
    Publishing date 2022-03-28
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.868067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A Novel Quantification System Combining iTRAQ Technology and Multi-Omics Assessment to Predict Prognosis and Immunotherapy Efficacy in Colon Cancer.

    Xia, Tianyi / Guo, Junnan / Zhang, Bomiao / Xue, Weinan / Deng, Shenhui / Liu, Yanlong / Cui, Binbin

    Frontiers in bioengineering and biotechnology

    2022  Volume 10, Page(s) 862619

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2022-04-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2022.862619
    Database MEDical Literature Analysis and Retrieval System OnLINE

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