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  1. Article: Postural balance disorders in sarcopenia based on surface electromyography.

    Zhang, Ting / Huo, Yang / Yin, Wenjing / Xiang, Jie

    Heliyon

    2024  Volume 10, Issue 1, Page(s) e24116

    Abstract: Background: Sarcopenia is an intrinsic factor that leads to balance disorders and falls in older adults. However, the characterization of sarcopenia-related postural balance deficits remains unclear.: Aims: This study aimed to explore the balance ... ...

    Abstract Background: Sarcopenia is an intrinsic factor that leads to balance disorders and falls in older adults. However, the characterization of sarcopenia-related postural balance deficits remains unclear.
    Aims: This study aimed to explore the balance performance and postural control strategy in older adults with sarcopenia during static stance tasks using force platforms and surface electromyography.
    Methods: Older adults with right-sided dominance were recruited, including 27 adults with sarcopenia and 27 healthy counterparts. Postural sway was measured with eyes open/closed on rigid/compliant surfaces. The time- and frequency-domain indexes of bilateral lower extremity muscle activity were simultaneously recorded.
    Results: The postural sway and activity of multiple lower extremity muscles in the sarcopenia group were increased (
    Conclusion: The results of this study suggest that older adults with sarcopenia have decreased balance function and increased cost of electrophysiology. They were found to prefer the postural strategy of dominant ankle dorsiflexion and demonstrated overactivity of the dominant tibialis anterior muscles and fatigue vulnerability of the nondominant gluteus maximus. Improvements in these postural features may have balance benefits.
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e24116
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  2. Article: Effect of the home care model in orthopedic wounds management.

    Lei, Xinhuan / Xiang, Jie / Chen, Xiaoxiao / Pan, Wenjun

    Journal of family medicine and primary care

    2023  Volume 12, Issue 12, Page(s) 3285–3290

    Abstract: Objective: To explore the effect of home care on orthopedic wound management.: Materials and methods: Patients with orthopedic wounds admitted from January 2020 to December 2022 were divided into a control group and a nursing group, with 23 cases in ... ...

    Abstract Objective: To explore the effect of home care on orthopedic wound management.
    Materials and methods: Patients with orthopedic wounds admitted from January 2020 to December 2022 were divided into a control group and a nursing group, with 23 cases in each group. After discharge, the control group was given routine health guidance and the nursing group was given home care. The mood score of the two groups of patients was evaluated, the time and cost were compared, and the patients' degree of trust and satisfaction with the medical staff were investigated.
    Results: The patients received home care had higher scores in mood, degree of trust and satisfaction with medical staff, and spent less time (
    Conclusions: Home care for patients with orthopedic wounds can significantly reduce the time spent on medical treatment. Moreover, improve patients' moods and trust and satisfaction with medical staff in a certain extent. However, better service often means more economic cost.
    Language English
    Publishing date 2023-12-21
    Publishing country India
    Document type Journal Article
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_876_23
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  3. Article ; Online: Association of magnesium sulfate use with mortality in critically ill patients with sepsis. Response to Br J Anaesth 2024; 132: 187.

    Gu, Wan-Jie / Duan, Xiang-Jie / Yin, Hai-Yan

    British journal of anaesthesia

    2023  Volume 132, Issue 2, Page(s) 442–443

    MeSH term(s) Humans ; Critical Illness ; Intensive Care Units ; Magnesium ; Magnesium Sulfate/adverse effects ; Magnesium Sulfate/therapeutic use ; Patients ; Sepsis/drug therapy ; Sepsis/mortality
    Chemical Substances Magnesium (I38ZP9992A) ; Magnesium Sulfate (7487-88-9)
    Language English
    Publishing date 2023-12-19
    Publishing country England
    Document type Letter
    ZDB-ID 80074-0
    ISSN 1471-6771 ; 0007-0912
    ISSN (online) 1471-6771
    ISSN 0007-0912
    DOI 10.1016/j.bja.2023.11.034
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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.80: Show issues Location:
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  4. Article ; Online: A promising PET tracer candidate targeting α-synuclein inclusions.

    Xiang, Jie / Zhang, Zhentao / Ye, Keqiang

    Clinical and translational medicine

    2023  Volume 13, Issue 9, Page(s) e1408

    MeSH term(s) alpha-Synuclein ; Positron-Emission Tomography
    Chemical Substances alpha-Synuclein
    Language English
    Publishing date 2023-09-07
    Publishing country United States
    Document type Letter
    ZDB-ID 2697013-2
    ISSN 2001-1326 ; 2001-1326
    ISSN (online) 2001-1326
    ISSN 2001-1326
    DOI 10.1002/ctm2.1408
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  5. Article ; Online: Repressing miR-23a promotes the transdifferentiation of pancreatic α cells to β cells via negatively regulating the expression of SDF-1α.

    Lang, Hongmei / Lin, Ning / Chen, Xiaorong / Xiang, Jie / Zhang, Xingping / Kang, Chao

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0299821

    Abstract: Pancreatic β-cell failure is a pathological feature in type 1 diabetes. One promising approach involves inducing transdifferentiation of related pancreatic cell types, specifically α cells that produce glucagon. The chemokine stromal cell-derived factor- ... ...

    Abstract Pancreatic β-cell failure is a pathological feature in type 1 diabetes. One promising approach involves inducing transdifferentiation of related pancreatic cell types, specifically α cells that produce glucagon. The chemokine stromal cell-derived factor-1 alpha (SDF-1α) is implicated in pancreatic α-to-β like cell transition. Here, the serum level of SDF-1α was lower in T1D with C-peptide loss, the miR-23a was negatively correlated with SDF-1α. We discovered that exosomal miR-23a, secreted from β cells, functionally downregulates the expression of SDF-1α, leading to increased Pax4 expression and decreased Arx expression in vivo. Adenovirus-vectored miR-23a sponge and mimic were constructed to further explored the miR-23a on pancreatic α-to-β like cell transition in vitro, which yielded results consistent with our cell-based assays. Suppression of miR-23a upregulated insulin level and downregulated glucagon level in STZ-induced diabetes mice models, effectively promoting α-to-β like cell transition. Our findings highlight miR-23a as a new therapeutic target for regenerating pancreatic β cells from α cells.
    MeSH term(s) Animals ; Mice ; Cell Transdifferentiation/genetics ; Chemokine CXCL12/genetics ; Chemokine CXCL12/metabolism ; Glucagon ; Glucagon-Secreting Cells/metabolism ; Insulin-Secreting Cells/metabolism ; MicroRNAs/genetics ; MicroRNAs/metabolism
    Chemical Substances Chemokine CXCL12 ; Glucagon (9007-92-5) ; MicroRNAs ; Mirn23b microRNA, mouse
    Language English
    Publishing date 2024-03-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0299821
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  6. Article ; Online: Multi-Stimulus Least-Squares Transformation With Online Adaptation Scheme to Reduce Calibration Effort for SSVEP-Based BCIs.

    Li, Dandan / Wang, Xuedong / Dou, Mingliang / Zhao, Yao / Cui, Xiaohong / Xiang, Jie / Wang, Bin

    IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society

    2024  Volume 32, Page(s) 1606–1615

    Abstract: Steady-state visual evoked potential (SSVEP), one of the most popular electroencephalography (EEG)-based brain-computer interface (BCI) paradigms, can achieve high performance using calibration-based recognition algorithms. As calibration-based ... ...

    Abstract Steady-state visual evoked potential (SSVEP), one of the most popular electroencephalography (EEG)-based brain-computer interface (BCI) paradigms, can achieve high performance using calibration-based recognition algorithms. As calibration-based recognition algorithms are time-consuming to collect calibration data, the least-squares transformation (LST) has been used to reduce the calibration effort for SSVEP-based BCI. However, the transformation matrices constructed by current LST methods are not precise enough, resulting in large differences between the transformed data and the real data of the target subject. This ultimately leads to the constructed spatial filters and reference templates not being effective enough. To address these issues, this paper proposes multi-stimulus LST with online adaptation scheme (ms-LST-OA).
    Methods: The proposed ms-LST-OA consists of two parts. Firstly, to improve the precision of the transformation matrices, we propose the multi-stimulus LST (ms-LST) using cross-stimulus learning scheme as the cross-subject data transformation method. The ms-LST uses the data from neighboring stimuli to construct a higher precision transformation matrix for each stimulus to reduce the differences between transformed data and real data. Secondly, to further optimize the constructed spatial filters and reference templates, we use an online adaptation scheme to learn more features of the EEG signals of the target subject through an iterative process trial-by-trial.
    Results: ms-LST-OA performance was measured for three datasets (Benchmark Dataset, BETA Dataset, and UCSD Dataset). Using few calibration data, the ITR of ms-LST-OA achieved 210.01±10.10 bits/min, 172.31±7.26 bits/min, and 139.04±14.90 bits/min for all three datasets, respectively.
    Conclusion: Using ms-LST-OA can reduce calibration effort for SSVEP-based BCIs.
    MeSH term(s) Humans ; Evoked Potentials, Visual ; Calibration ; Brain-Computer Interfaces ; Photic Stimulation/methods ; Electroencephalography/methods ; Algorithms
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1166307-8
    ISSN 1558-0210 ; 1063-6528 ; 1534-4320
    ISSN (online) 1558-0210
    ISSN 1063-6528 ; 1534-4320
    DOI 10.1109/TNSRE.2024.3387283
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4726: Show issues Location:
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  7. Article ; Online: The relationship between red cell distribution width, serum calcium ratio, and in-hospital mortality among patients with acute respiratory failure: A retrospective cohort study of the MIMIC-IV database.

    Dai, Jun / Guo, Yafen / Zhou, Quan / Duan, Xiang-Jie / Shen, Jinhua / Zhang, Xueqing

    Medicine

    2024  Volume 103, Issue 15, Page(s) e37804

    Abstract: To investigate the impact of RDW/CA (the ratio of red cell distribution width to calcium) on in-hospital mortality in patients with acute respiratory failure (ARF). This retrospective cohort study analyzed the data of 6981 ARF patients from the Medical ... ...

    Abstract To investigate the impact of RDW/CA (the ratio of red cell distribution width to calcium) on in-hospital mortality in patients with acute respiratory failure (ARF). This retrospective cohort study analyzed the data of 6981 ARF patients from the Medical Information Mart for Intensive Care (MIMIC-IV) database 2.0. Critically ill participants between 2008 and 2019 at the Beth Israel Deaconess Medical Center in Boston. The primary outcome of interest was in-hospital mortality. A Cox proportional hazards regression model was used to determine whether the RDW/CA ratio independently correlated with in-hospital mortality. The Kaplan-Meier method was used to plot the survival curves of the RDW/CA. Subgroup analyses were performed to measure the mortality across various subgroups. After adjusting for potential covariates, we found that a higher RDW/CA was associated with an increased risk of in-hospital mortality (HR = 1.17, 95% CI: 1.01-1.35, P = .0365) in ARF patients. A nonlinear relationship was observed between RDW/CA and in-hospital mortality, with an inflection point of 1.97. When RDW/CA ≥ 1.97 was positively correlated with in-hospital mortality in patients with ARF (HR = 1.554, 95% CI: 1.183-2.042, P = .0015). The Kaplan-Meier curve indicated the higher survival rates for RDW/CA < 1.97 and the lower for RDW/CA ≥ 1.97 after adjustment for age, gender, body mass index, and ethnicity. RDW/CA is an independent predictor of in-hospital mortality in patients with ARF. Furthermore, a nonlinear relationship was observed between RDW/CA and in-hospital mortality in patients with ARF.
    MeSH term(s) Humans ; Hospital Mortality ; Erythrocyte Indices ; Calcium ; Retrospective Studies ; Respiratory Distress Syndrome ; Respiratory Insufficiency
    Chemical Substances Calcium (SY7Q814VUP)
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000037804
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    Ua VI Zs.171: Show issues Location:
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  8. Article ; Online: Applicability of Nuclear Magnetic Resonance Experiment in Analyzing Pore and Fluid Distribution Characteristics of Tight Sandstone: A Case Study in the Julu Area, Bohai Bay Basin, China.

    Jiang, Zhenfei / Zhu, Yanming / Li, Peng / Wang, Yang / Xiang, Jie

    ACS omega

    2023  Volume 8, Issue 46, Page(s) 43903–43919

    Abstract: Characterizing the pore and fluid distribution is critical for evaluating the reservoir potential of new areas. Nuclear magnetic resonance (NMR) is considered as an experimental method capable of full-scale characterization of pore characteristics. ... ...

    Abstract Characterizing the pore and fluid distribution is critical for evaluating the reservoir potential of new areas. Nuclear magnetic resonance (NMR) is considered as an experimental method capable of full-scale characterization of pore characteristics. However, the
    Language English
    Publishing date 2023-11-08
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c05894
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  9. Article ; Online: Anti-inflammatory compounds from the rhizome of

    Huang, Liping / Feng, Zhenying / Xiang, Jie / Deng, Minzhen / Zhou, Zhongliu

    Natural product research

    2023  , Page(s) 1–7

    Abstract: Seven compounds, named β-sitosterol ( ...

    Abstract Seven compounds, named β-sitosterol (
    Language English
    Publishing date 2023-09-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2023.2255919
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  10. Article: The effect of PINK1/Parkin pathway on glucose homeostasis imbalance induced by tacrolimus in mouse livers.

    Li, Zhiwei / Xiang, Jie / Mei, Shengmin / Wu, Yue / Xu, Yuan

    Heliyon

    2023  Volume 9, Issue 4, Page(s) e15536

    Abstract: Treatment using the immunosuppressive drug tacrolimus (TAC) is related to new-onset diabetes after transplantation (NODAT). Previous studies focused mainly on islet β cells in the diabetogenic effect of TAC. Herein, we revealed that NODAT was probably ... ...

    Abstract Treatment using the immunosuppressive drug tacrolimus (TAC) is related to new-onset diabetes after transplantation (NODAT). Previous studies focused mainly on islet β cells in the diabetogenic effect of TAC. Herein, we revealed that NODAT was probably induced by TAC via hepatic insulin resistance. After daily injection of mice with TAC, a glucose metabolism disorder was induced. In addition, TAC decreased the mRNA and protein levels of insulin receptor substrate 2 (IRS2), glucose transporter type 2 (GLUT2), and the phosphorylation of protein kinase B beta (pAKT2), which indicated impaired hepatic insulin signaling. Furthermore, the PTEN-induced novel kinase 1(PINK1)/Parkin pathway was shown to have a key role in the TAC-induced imbalance of hepatic glucose homeostasis. Mechanistic investigations in human hepatic cell lines revealed that TAC stimulated PINK1/Parkin expression and inhibited the expression of insulin signaling related molecules (e.g., IRS2, GLUT2 and pAKT2). Knockdown of hepatic
    Language English
    Publishing date 2023-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e15536
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