Article: [Diagnostic Application of Invasive Cardiopulmonary Exercise Test in Patients with Unexplained Dyspnea].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
2021 Volume 52, Issue 1, Page(s) 142–148
Abstract: Objective: To explore the clinical diagnostic application of invasive cardiopulmonary exercise test (iCPET) in patients with unexplained dyspnea.: Methods: A retrospective analysis was conducted, covering patients with a chief complaint of exertional ...
| Abstract | Objective: To explore the clinical diagnostic application of invasive cardiopulmonary exercise test (iCPET) in patients with unexplained dyspnea. Methods: A retrospective analysis was conducted, covering patients with a chief complaint of exertional dyspnea between May 5, 2017 and October 1, 2020. Right cardiac catheterization examination was performed on patients whose cause had not been identified through routine examination, and further iCPET was performed on patients if no clear etiology was identified through right cardiac catheterization. According to the results and the diagnostic criteria of iCPET, patients showing no obvious abnormalities in the right cardiac catheterization examination were divided into four subgroups: exercise-induced pulmonary arterial hypertension (eiPAH), exercise-induced heart failure with preserved ejection fraction (eiHFpEF), preload failure, and oxidative myopathy. By comparing the lab test, echocardiography, right heart catheter and iCPET peak exercise data of the subgroups, the disease distribution and exercise hemodynamic characteristics of patients with unexplained dyspnea examined by iCPET were described. Results: Of the 1 046 patients with exertional dyspnea, 771 were diagnosed with routine examination, while among the remaining 275 patients, 131 (47.6%) were diagnosed with right cardiac catheterization and 144 (52.4%) showed no clear etiology after routine examination and right cardiac catheterization. Of these 144 patients, 49 (34.0%) received iCPET with a median exercise time of 375 s. A total of 47 patients completed the examination, with a male-to-female ratio of 0.27∶1 and an average age of (47.9±14.4) years old. Among the 47 patients, 76.6% (36/47) aged between 20 and 59 and 78.7% (36/47) lived in urban areas. The preload failure group ( |
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| MeSH term(s) | Adult ; Cardiac Catheterization ; Dyspnea/etiology ; Exercise Test ; Exercise Tolerance ; Female ; Heart Failure/diagnosis ; Heart Failure/diagnostic imaging ; Humans ; Male ; Middle Aged ; Pulmonary Wedge Pressure ; Retrospective Studies |
| Language | Chinese |
| Publishing date | 2021-01-20 |
| Publishing country | China |
| Document type | Journal Article |
| ZDB-ID | 2106840-9 |
| ISSN | 1672-173X |
| ISSN | 1672-173X |
| DOI | 10.12182/20210160205 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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