Article: [Effects of Kang Gang Qian Granule (KGQG) on clinical and pathological features in chronic hepatitis B patients].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology
2007 Volume 21, Issue 4, Page(s) 369–371
Abstract: Objective: To explore the efficacy of KGQG and its therapeutic mechanisms in chronic hepatitis B patients with liver fibrosis.: Methods: 57 chronic hepatitis B patients with liver fibrosis were randomly divided into two groups: 45 cases in KGQG group ...
| Abstract | Objective: To explore the efficacy of KGQG and its therapeutic mechanisms in chronic hepatitis B patients with liver fibrosis. Methods: 57 chronic hepatitis B patients with liver fibrosis were randomly divided into two groups: 45 cases in KGQG group were treated by KGQG and routine medications; 12 cases in control group were treated by routine medications only. Serum liver function test results, PCIII, CIV, HA and liver biopsy results of these 57 patients were simultaneously collected and analyzed before and after this intervention. Results: KGQG group showed better efficacy over control group in liver function recovery, decrease of serum PCIII, CIV, HA levels and liver pathologic grades (P 0.05 or 0.01). Conclusion: The KGQG could effectively ameliorate liver function and facilitate the inhibition and degradation of liver fibrosis in chronic hepatitis B patients, which may be developed as a novel therapeusis to treat this hard-to-cure disease. |
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| MeSH term(s) | Adolescent ; Adult ; Collagen Type IV/analysis ; Drugs, Chinese Herbal/therapeutic use ; Female ; Hepatitis B, Chronic/drug therapy ; Hepatitis B, Chronic/pathology ; Hepatitis B, Chronic/physiopathology ; Humans ; Immunohistochemistry ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/pathology ; Male ; Medicine, Chinese Traditional ; Middle Aged |
| Chemical Substances | Collagen Type IV ; Drugs, Chinese Herbal |
| Language | Chinese |
| Publishing date | 2007-12 |
| Publishing country | China |
| Document type | English Abstract ; Journal Article ; Randomized Controlled Trial |
| ISSN | 1003-9279 |
| ISSN | 1003-9279 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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