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Article ; Online: Sliding Mode Control of the Vehicle Speed System Based on LMIs

Hong-Liang Gao / Hong-Cong Zhang / Xiao-Ling Li

Complexity, Vol

2021 Volume 2021

Abstract: Due to the nonlinear characteristics of the vehicle speed system, its stability is difficult to control. This paper analyzes the stability and traceability of the vehicle speed system under nonlinear characteristics. A sliding mode control method of the ... ...

Abstract	Due to the nonlinear characteristics of the vehicle speed system, its stability is difficult to control. This paper analyzes the stability and traceability of the vehicle speed system under nonlinear characteristics. A sliding mode control method of the nonlinear system state observation based on linear matrix inequalities (LMIs) is proposed. In the proposed control method, Lyapunov function is used as the control function to track the position and speed of the vehicle speed system in real time. In the design process of the controller, the successive scaling method (SSM) is designed to improve the tracking accuracy. The simulation results demonstrate that the sliding mode control can effectively track the position of the vehicle speed system, which has better stability and traceability for the nonlinear vehicle speed system.
Keywords	Electronic computers. Computer science ; QA75.5-76.95
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi-Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Diagnostic utility of HFLC% and IG% for acute Pancreatitis-A retrospective Case-Control study.

Xiao-Yan, Lin / Xiao-Ling, Li / Le-Xin, Zhang / Nan, Sheng / Yu, Chen / Hui-Heng, Liu

Heliyon

2024 Volume 10, Issue 9, Page(s) e30031

Abstract: Objective: To evaluate the occurrence, development and outcome value of hyperfluorescent lymphocyte percentage (HFLC%) and immature granulocyte percentage (IG%) for acute pancreatitis (AP).: Methods: The laboratory data collected from 1533 patients ... ...

Abstract	Objective: To evaluate the occurrence, development and outcome value of hyperfluorescent lymphocyte percentage (HFLC%) and immature granulocyte percentage (IG%) for acute pancreatitis (AP). Methods: The laboratory data collected from 1533 patients diagnosed with AP between August 2018 and August 2022 were retrospectively analyzed. The patients were classified into mild acute pancreatitis (MAP) and non-mild acute pancreatitis (Non-MAP) groups; non-MAP groups were additionally subgrouped based on HFLC% at day 7. White blood cells (WBC), HFLC%, and IG% were examined from day 1 (baseline) to day 14 post-admission using Sysmex XN Series Hematology Analyzers. C-reactive protein (CRP), serum amylase (AMY), and lipase (LPS) were detected by Beckman AU5800. Results: A total of 623 patients were finally included in the study [MAP group (n = 358) and Non-MAP group (n = 265)]. WBC, IG%, and CRP were higher in the Non-MAP group from day 1 to day 12 (all Conclusion: HFLC% <2.9 % on 7th day was directly indicated more infection, systemic inflammatory response syndrome(SIRS), higher APPACH II grade and ICU admission. HFLC% may be an independent laboratory marker for prognosis in AP. Combining HFLC% with IG%, CRP, and WBC helps evaluate AP patients' disease development and outcome.
Language	English
Publishing date	2024-04-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e30031
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Relationship of visual quality and postoperative dominant eye changes with age-related cataract

Xiao-Ling Li

Guoji Yanke Zazhi, Vol 15, Iss 5, Pp 866-

2015 Volume 868

Abstract: AIM: To investigate age-related cataract and its postoperative dominant eye changes and visual quality of patients. METHODS: Totally 102 patients(204 eyes)with age-related cataract in our hospital from January 2013 to November 2014 were selected, and ... ...

Abstract	AIM: To investigate age-related cataract and its postoperative dominant eye changes and visual quality of patients. METHODS: Totally 102 patients(204 eyes)with age-related cataract in our hospital from January 2013 to November 2014 were selected, and according to preoperative best corrected visual acuity(BCVA)were divided into two groups, in which the both eyes BCVA difference ≥2 lines(78 cases, 156 eyes)was group A, and both eyes BCVA difference ≤1 line(24 cases, 48 eyes)was group B. Dominant eyes were detected preoperatively and at postoperative 1 and 3mo. Contrast sensitivity and investigated visual satisfaction were tested. RESULTS: Preoperative dominant eye corrected visual acuity was 0.34 ± 0.11, significantly higher than that of the non-dominant eye(0.15 ± 0.09), and there was statistically significant difference( P <0.05); At postoperative 1 and 3mo,between corrected visual acuity difference dominant eyes and the non-dominant eyes was not statistically significant( P >0.05); At postoperative 3mo, 17 cases in the group A had dominant eye changes, and change rate was 21.79%(17/78). At postoperative 3mo, the dominant eye change rate in the group B was 20.83%(5/24), and there was no statistical significant difference between the two groups( P >0.05). The dominant eye change group and non-change groups patients with different spatial frequency contrast sensitivity test showed no statistical significance( P >0.05), Postoperative 3mo after operationvisual satisfaction questionnaire display, score of group A was(91.35±10.26)points, score of group B was(90.15±9.75)points( P >0.05), the dominant eye change group score was(90.08±9.77)points, score non-change group was(91.43±10.22)points( P >0.05). CONCLUSION: The dominant eye changes exist in postoperative eyes with age-related cataract, but there is no effect on visual quality.
Keywords	dominant eye ; age-related cataract ; visual quality ; Ophthalmology ; RE1-994 ; Medicine ; R
Subject code	796
Language	Chinese
Publishing date	2015-05-01T00:00:00Z
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The functional change of the P2X7R containing the Ala348 to Thr polymorphism is associated with the pathogenesis of gout

Man-Yun Li / Xuan Fang / Yan Ma / Xian-Yang Pan / Xiao-Juan Dai / Xiao-Mei Li / Xiao-Ling Li / Yi-Ping Wang / Jin-Hui Tao / Xiang-Pei Li

Scientific Reports, Vol 13, Iss 1, Pp 1-

2023 Volume 9

Abstract: Abstract Our previous study has shown that ATP action on P2X7R could be the second signal to induce the onset of gouty arthritis. However, the functional changes of P2X7R single nucleotide polymorphisms (SNPs) on the effects of ATP-P2X7R-IL-1β signaling ... ...

Abstract	Abstract Our previous study has shown that ATP action on P2X7R could be the second signal to induce the onset of gouty arthritis. However, the functional changes of P2X7R single nucleotide polymorphisms (SNPs) on the effects of ATP-P2X7R-IL-1β signaling pathway and uric acid remained unknown. We aimed to investigate the association between the functional change of P2X7R containing the Ala348 to Thr polymorphisms (rs1718119) and the pathogenesis of gout. First, 270 gout patients and 70 hyperuricemic patients (without gout attack history in recent 5 years) were recruited for genotyping. In addition, the changes of ATP-induced pore formation were assessed in HEK-293T cells overexpressing different mutants in P2RX7, and the effects on P2X7R-NLRP3-IL-1β pathway activation were explored in P2RX7 overexpression THP-1 cells. The risk allele for gout was A at rs1718119, and the AA and AG genotypes exhibited a higher risk of gout. Furthermore, Ala348 to Thr mutants increased P2X7-dependent ethidium+ bromide uptake, upregulated IL-1β and NLRP3 levels as compared to the wild-type. We suggest that genetic polymorphisms of P2X7R containing the Ala348 to Thr are associated with the increased risk of gout, showing an enhanced gain-of-function effect on the development of this disease.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Matrin3 regulates mitotic spindle dynamics by controlling alternative splicing of CDC14B

Bruna R. Muys / Roshan L. Shrestha / Dimitrios G. Anastasakis / Lorinc Pongor / Xiao Ling Li / Ioannis Grammatikakis / Ahsan Polash / Raj Chari / Myriam Gorospe / Curtis C. Harris / Mirit I. Aladjem / Munira A. Basrai / Markus Hafner / Ashish Lal

Cell Reports, Vol 42, Iss 3, Pp 112260- (2023)

2023

Abstract: Summary: Matrin3 is an RNA-binding protein that regulates diverse RNA-related processes, including mRNA splicing. Although Matrin3 has been intensively studied in neurodegenerative diseases, its function in cancer remains unclear. Here, we report Matrin3- ...

Abstract	Summary: Matrin3 is an RNA-binding protein that regulates diverse RNA-related processes, including mRNA splicing. Although Matrin3 has been intensively studied in neurodegenerative diseases, its function in cancer remains unclear. Here, we report Matrin3-mediated regulation of mitotic spindle dynamics in colorectal cancer (CRC) cells. We comprehensively identified RNAs bound and regulated by Matrin3 in CRC cells and focused on CDC14B, one of the top Matrin3 targets. Matrin3 knockdown results in increased inclusion of an exon containing a premature termination codon in the CDC14B transcript and simultaneous down-regulation of the standard CDC14B transcript. Knockdown of CDC14B phenocopies the defects in mitotic spindle dynamics upon Matrin3 knockdown, and the elongated and misoriented mitotic spindle observed upon Matrin3 knockdown are rescued upon overexpression of CDC14B, suggesting that CDC14B is a key downstream effector of Matrin3. Collectively, these data reveal a role for the Matrin3/CDC14B axis in control of mitotic spindle dynamics.
Keywords	CP: Cell biology ; CP: Molecular biology ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
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Article ; Online: A Generic Software Monitoring Model and Features Analysis

Chang-Guo Guo / Jun Zhu / Xiao-Ling Li

Journal of Software, Vol 6, Iss 3, Pp 395-

2011 Volume 403

Abstract: Software runtime monitoring has been used to increase the dependability of software. This paper focuses on software runtime monitoring techniques and tools. A generic software runtime monitoring model is presented, which consists of five basic elements, ... ...

Abstract	Software runtime monitoring has been used to increase the dependability of software. This paper focuses on software runtime monitoring techniques and tools. A generic software runtime monitoring model is presented, which consists of five basic elements, i.e., Monitored Object Features, Monitoring Access Methods, Execution Relationships, Runtime Monitor and Platform Dependencies. This model is an innovation in software monitoring fields. This paper gives some features of each element. Based on these features, researchers can use the model to comprehend and analyze runtime monitoring techniques and tools. The objective of this paper is to help researchers and users to identify the difference and the basic principles of software runtime monitoring techniques and tools. This paper also shows a result of relationship between techniques and features, through the result, we can understand the development trends of the techniques and tools, such as, what features are concerned more, and what features are concerned less.
Keywords	software runtime monitoring ; dependability ; monitoring access methods ; monitored object features ; runtime monitor ; Electronic computers. Computer science ; QA75.5-76.95 ; Instruments and machines ; QA71-90 ; Mathematics ; QA1-939 ; Science ; Q
Subject code	005
Language	English
Publishing date	2011-03-01T00:00:00Z
Publisher	ACADEMY PUBLISHER
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genetic diversity and population structure of Distylium chinense revealed by ISSR and SRAP analysis in the Three Gorges Reservoir Region of the Yangtze River, China

Ling Xiang / Xiao-Ling Li / Xue-Song Wang / Jin Yang / Kun Lv / Zi-Qian Xiong / Fang-Qing Chen / Cheng-Ming Huang

Global Ecology and Conservation, Vol 21, Iss , Pp - (2020)

2020

Abstract: Distylium chinense is a dominant native evergreen shrub or small tree in the riparian forests in the Three Gorges Reservoir zone in China. The genetic diversity and population structure of D. chinense within and among eight populations was analyzed by ... ...

Abstract	Distylium chinense is a dominant native evergreen shrub or small tree in the riparian forests in the Three Gorges Reservoir zone in China. The genetic diversity and population structure of D. chinense within and among eight populations was analyzed by ISSR (Inter Simple Sequence Repeat) and SRAP (Sequence-Related Amplified Polymorphism) markers. A high level of genetic diversity was observed at the species level (H = 0.3465, I = 0.5039 in ISSR; H = 0.1924, I = 0.4123 in SRAP) and at the population level (H = 0.3047, I = 0.4471 in ISSR; H = 0.1543, I = 0.3415 in SRAP). The genetic differentiation among population (Gst = 0.1205, Nm = 1.8247 in ISSR and Gst = 0.1976, Nm = 1.015 in SRAP) indicated low levels of genetic variation among populations and high levels of genetic polymorphism within populations. AMOVA (Analyses of molecular variance) also suggested that the main source of variation was within populations (93.9% in ISSR and SRAP in 81.9%). UPGMA (Unweighted Pair Group Method with Arithmetic means) cluster analysis and PCA (Principal Component Analysis) based on ISSR and SRAP amplification showed that populations from the same or adjacent regions were classified together. However, Mantel's test demonstrated that there was no significant correlation between the genetic distance and the geographical distance of each population (P > 0.05). Thus, the declining status of this species is likely due to the destruction of natural habitats, anthropogenic activities and overharvesting, rather than a loss of genetic diversity. Keywords: Distylium chinense, ISSR, SRAP, Genetic structure, Genetic diversity
Keywords	Ecology ; QH540-549.5
Subject code	580
Language	English
Publishing date	2020-03-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Transcriptome guided identification of novel functions of RECQ1 helicase

Lu, Xing / Ashish Lal / Sudha Sharma / Swetha Parvathaneni / Xiao Ling Li

Elsevier Inc. Methods. 2016 Oct. 01, v. 108

2016

Abstract: Gene expression changes in the functional absence of a specific RecQ protein, and how that relates to disease outcomes including cancer predisposition and premature aging in RecQ helicase associated syndromes, are poorly understood. Here we describe ... ...

Abstract	Gene expression changes in the functional absence of a specific RecQ protein, and how that relates to disease outcomes including cancer predisposition and premature aging in RecQ helicase associated syndromes, are poorly understood. Here we describe detailed experimental strategy for identification of RECQ1-regulated transcriptome that led us to uncover a novel association of RECQ1 in regulation of cancer cell migration and invasion. We initiated a focused study to determine whether RECQ1, the most abundant RecQ protein in humans, alters gene expression and also investigated whether RECQ1 binds with G4 motifs predicted to form G-quadruplex structures in the target gene promoters. Rescue of mRNA expression of select RECQ1-downregulated genes harboring G4 motifs required wild-type RECQ1 helicase. However, some RECQ1-regulated genes are also regulated by BLM and WRN proteins regardless of the presence or absence of G4 motifs. The approach described here is applicable for systematic comparison of gene expression signatures of individual RecQ proteins in isogenic background, and to elucidate their participation in transcription regulation through G-quadruplex recognition and/or resolution. Such strategies might also reveal molecular pathways that drive the pathogenesis of cancer and other diseases in specific RecQ deficiency.
Keywords	cell movement ; gene expression ; gene expression regulation ; genes ; humans ; messenger RNA ; neoplasms ; pathogenesis ; proteins ; transcription (genetics) ; transcriptome
Language	English
Dates of publication	2016-1001
Size	p. 111-117.
Publishing place	Elsevier Inc.
Document type	Article
ZDB-ID	1066584-5
ISSN	1095-9130 ; 1046-2023
ISSN (online)	1095-9130
ISSN	1046-2023
DOI	10.1016/j.ymeth.2016.04.018
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Behavioral and Psychological Symptoms in Alzheimer’s Disease

Xiao-Ling Li / Nan Hu / Meng-Shan Tan / Jin-Tai Yu / Lan Tan

BioMed Research International, Vol

2014 Volume 2014

Abstract: Neuropsychiatric symptoms (NPS) such as depression, apathy, aggression, and psychosis are now recognized as core features of Alzheimer’s disease (AD), and there is a general consensus that greater symptom severity is predictive of faster cognitive ... ...

Abstract	Neuropsychiatric symptoms (NPS) such as depression, apathy, aggression, and psychosis are now recognized as core features of Alzheimer’s disease (AD), and there is a general consensus that greater symptom severity is predictive of faster cognitive decline, loss of independence, and even shorter survival. Whether these symptoms result from the same pathogenic processes responsible for cognitive decline or have unique etiologies independent of AD-associated neurodegeneration is unclear. Many structural and metabolic features of the AD brain are associated with individual neuropsychiatric symptoms or symptom clusters. In addition, many genes have been identified and confirmed that are associated with symptom risk in a few cases. However, there are no single genes strongly predictive of individual neuropsychiatric syndromes, while functional and structural brain changes unique to specific symptoms may reflect variability in progression of the same pathological processes. Unfortunately, treatment success for these psychiatric symptoms may be lower when comorbid with AD, underscoring the importance of future research on their pathobiology and treatment. This review summarizes some of the most salient aspects of NPS pathogenesis.
Keywords	Medicine ; R
Subject code	150
Language	English
Publishing date	2014-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: catena-Poly[[(2,2′-bipyridine)copper(II)]-μ-5-tert-butylisophthalato]

Miao-Ling Huang / Xiao-Ling Li

Acta Crystallographica Section E, Vol 64, Iss 12, Pp m1501-m

2008 Volume 1502

Abstract: In the crystal structure of the title polymeric compound, [Cu(C12H12O4)(C10H8N2)]n, the asymmetric unit consists of one CuII ion, one 5-tert-butylisophthalate (tbip) and one 2,2′-bipyridine (bpy) ligand. The copper(II) ion is four-coordinated by two N ... ...

Abstract	In the crystal structure of the title polymeric compound, [Cu(C12H12O4)(C10H8N2)]n, the asymmetric unit consists of one CuII ion, one 5-tert-butylisophthalate (tbip) and one 2,2′-bipyridine (bpy) ligand. The copper(II) ion is four-coordinated by two N atoms from bipy and two O atoms from two tbip ligands, leading to a distorted tetrahedral coordination. Each tbip ligand adopts a bis-monodentate coordination mode to connect two symmetry-related copper(II) ions, so forming a zigzag polymer chain parallel to [001]. The tert-butyl methyl groups are disordered over two positions with occupancies of 0.506 (6)/0.494 (6)
Keywords	Chemistry ; QD1-999
Language	English
Publishing date	2008-12-01T00:00:00Z
Publisher	International Union of Crystallography
Document type	Article ; Online
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