LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 6 of total 6

Search options

  1. Article ; Online: Rapid alkalinization factor

    Ran Zhang / Peng-Tao Shi / Min Zhou / Huai-Zeng Liu / Xiao-Jing Xu / Wen-Ting Liu / Kun-Ming Chen

    Stress Biology, Vol 3, Iss 1, Pp 1-

    function, regulation, and potential applications in agriculture

    2023  Volume 23

    Abstract: Abstract Rapid alkalinization factor (RALF) is widespread throughout the plant kingdom and controls many aspects of plant life. Current studies on the regulatory mechanism underlying RALF function mainly focus on Arabidopsis, but little is known about ... ...

    Abstract Abstract Rapid alkalinization factor (RALF) is widespread throughout the plant kingdom and controls many aspects of plant life. Current studies on the regulatory mechanism underlying RALF function mainly focus on Arabidopsis, but little is known about the role of RALF in crop plants. Here, we systematically and comprehensively analyzed the relation between RALF family genes from five important crops and those in the model plant Arabidopsis thaliana. Simultaneously, we summarized the functions of RALFs in controlling growth and developmental behavior using conservative motifs as cues and predicted the regulatory role of RALFs in cereal crops. In conclusion, RALF has considerable application potential in improving crop yields and increasing economic benefits. Using gene editing technology or taking advantage of RALF as a hormone additive are effective way to amplify the role of RALF in crop plants.
    Keywords RALF ; Fertilization ; Stress ; Crops ; Molecular regulatory network ; Biology (General) ; QH301-705.5
    Subject code 580
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher Springer
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Revisiting the molecular mechanisms and adaptive strategies associated with drought stress tolerance in common wheat (Triticum aestivum L.)

    Nadeem Bhanbhro / Hong-Jin Wang / Hao Yang / Xiao-Jing Xu / Ali Murad Jakhar / Abdullah shalmani / Rui-Xiang Zhang / Qadir Bakhsh / Ghulam Akbar / Muhammad Iqbal Jakhro / Yaseen Khan / Kun-Ming Chen

    Plant Stress, Vol 11, Iss , Pp 100298- (2024)

    1481  

    Abstract: Drought is a misfortune for crops. Wheat is a staple crop and its sustainability and adequate supply are vital to food security around the world. The development of drought-tolerant cultivars in wheat is a major challenge to breeders, therefore there is ... ...

    Abstract Drought is a misfortune for crops. Wheat is a staple crop and its sustainability and adequate supply are vital to food security around the world. The development of drought-tolerant cultivars in wheat is a major challenge to breeders, therefore there is dire need of time to determine the genetic components of drought tolerance in wheat crop. To overcome intense drought stress, wheat plants undergo certain morphological and physiological changes and develop certain genetically adaptive mechanisms. Since wheat is an allotriploid with three sub-genomes, its adaptability molecular mechanisms to drought, particularly needs scientific attention. Here, we systematically and comprehensively reviewed the causes of wheat drought tolerance and the consequences for wheat physiology and genetics. The quantitative trait loci (QTL), which be function on the control of wheat drought tolerance, were comprehensively summarized by a meta-analysis and total 75 meta-QTLs (MQTLs) were identified. In addition, we summarized the genes tightly involved in wheat drought tolerance, and several important genes were selected to elucidate signaling networks related to the wheat drought tolerance. This review is integral to growing suitable strains in the worldwide arid regions to improve wheat yields under recent global climate change scenarios.
    Keywords Drought tolerance ; wheat (Triticum aestivum L.) ; signaling networks ; phytohormones ; quantitative trait loci (QTL) ; Plant ecology ; QK900-989
    Subject code 571
    Language English
    Publishing date 2024-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Importance of stabilization of the neonatal transport network in critically ill neonates

    Xiao-Jing Xu / Li-Na Li / Wen-Yan Wu

    Journal of International Medical Research, Vol

    2019  Volume 47

    Abstract: Objective This study aimed to investigate how to stabilize the condition of critically ill neonates within the neonatal transport network. Methods A total of 243 critically ill newborns in four hospitals involved in the transport network were enrolled. ... ...

    Abstract Objective This study aimed to investigate how to stabilize the condition of critically ill neonates within the neonatal transport network. Methods A total of 243 critically ill newborns in four hospitals involved in the transport network were enrolled. The newborns were divided into the research and control groups. In the research group, medical staff underwent theoretical training, and neonatal intensive care unit (NICU) professionals participated and provided on-site guidance on delivery of high-risk infants. Delivery of high-risk neonates in the control group was conventionally managed in local hospitals, and neonates were transferred after a phone call to the NICU. Results Gestational age and body weight were lower, and dexamethasone use was higher in the research group than in the control group. The proportions of neonates who underwent mask pressure, endotracheal intubation, pulmonary surfactant application, and chest compressions were higher, and those with dyspnea and nervous system abnormalities were lower in the research group than in the control group. Blood gas and sugar levels were better in the research group than in the control group. Conclusion Strengthening professional training and participation of professional NICU staff in childbirth can improve the conditions of high-risk neonates and increase safety of their transportation.
    Keywords Medicine (General) ; R5-920
    Language English
    Publishing date 2019-08-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Virtual elastography ultrasound via generative adversarial network for breast cancer diagnosis

    Zhao Yao / Ting Luo / YiJie Dong / XiaoHong Jia / YinHui Deng / GuoQing Wu / Ying Zhu / JingWen Zhang / Juan Liu / LiChun Yang / XiaoMao Luo / ZhiYao Li / YanJun Xu / Bin Hu / YunXia Huang / Cai Chang / JinFeng Xu / Hui Luo / FaJin Dong /
    XiaoNa Xia / ChengRong Wu / WenJia Hu / Gang Wu / QiaoYing Li / Qin Chen / WanYue Deng / QiongChao Jiang / YongLin Mou / HuanNan Yan / XiaoJing Xu / HongJu Yan / Ping Zhou / Yang Shao / LiGang Cui / Ping He / LinXue Qian / JinPing Liu / LiYing Shi / YaNan Zhao / YongYuan Xu / WeiWei Zhan / YuanYuan Wang / JinHua Yu / JianQiao Zhou

    Nature Communications, Vol 14, Iss 1, Pp 1-

    2023  Volume 12

    Abstract: The current use of elastography ultrasound faces challenges, including vulnerability to subjective manipulation, echo signal attenuation, unknown risks of elastic pressure and high imaging hardware cost. Here, the author shows a virtual elastography to ... ...

    Abstract The current use of elastography ultrasound faces challenges, including vulnerability to subjective manipulation, echo signal attenuation, unknown risks of elastic pressure and high imaging hardware cost. Here, the author shows a virtual elastography to empower low-end ultrasound devices with state-of-art elastography function.
    Keywords Science ; Q
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Comprehensive analysis of the association of EGFR, CALM3 and SMARCD1 gene polymorphisms with BMD in Caucasian women.

    Qiu-Hong Zhou / Lan-Juan Zhao / Ping Wang / Rhamee Badr / Xiao-Jing Xu / Feng-Xiao Bu / Joan Lappe / Robert Recker / Yu Zhou / An Ye / Bo-Ting Zhou

    PLoS ONE, Vol 9, Iss 11, p e

    2014  Volume 112358

    Abstract: Three genes, including EGFR (epidermal growth factor receptor), CALM3 (calmodulin 3, calcium-modulated protein 3) and SMARCD1 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily d member 1), play different roles in bone ... ...

    Abstract Three genes, including EGFR (epidermal growth factor receptor), CALM3 (calmodulin 3, calcium-modulated protein 3) and SMARCD1 (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily d member 1), play different roles in bone and/or fat metabolism in Caucasian women. In this population-based investigation of 870 unrelated postmenopausal Caucasian women, CALM3 polymorphisms were significantly associated with femoral neck bone mineral density (FNK BMD), hip BMD and spine BMD. Age and tobacco status also affected BMD levels and were therefore corrected for in our statistical analysis.EGFR, CALM3 and SMARCD1 play roles in bone and/or fat metabolism. However, the correlations between the polymorphisms of these three genes and body composition levels, including BMD, remain to be determined.A population-based investigation of 870 white women was conducted. Forty-four SNPs (single nucleotide polymorphisms) in EGFR, CALM3 and SMARCD1 were chosen by the software, including those of potential functional importance. The candidate SNPs were genotyped by the KASPar assay for an association analysis with body composition levels. The correlation analysis was assessed by the Pearson's product-moment correlation coefficient and Spearman rank-order correlation tests, and the family-wise error was corrected using the Wald test implemented in PLINK.The SNP rs12461917 in the 3'-flanking region of the CALM3 gene was significantly associated with FNK BMD (P = 0.001), hip BMD (P<0.001) and spine BMD (P = 0.001); rs11083838 in the 5'-flanking region of CALM3 gene was associated with spine BMD (P = 0.009). After adjusting for multiple comparisons, rs12461917 remained significant (P-adjusted = 0.033 for FNK BMD, P-adjusted = 0.006 for hip BMD and P-adjusted = 0.018 for spine BMD).Our data show that polymorphisms of the CALM3 gene in Caucasian women may contribute to variations in the BMD of the hip, spine and femoral neck.
    Keywords Medicine ; R ; Science ; Q
    Subject code 616
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: The prognostic value of altered eIF3a and its association with p27 in non-small cell lung cancers.

    Jie Shen / Ji-Ye Yin / Xiang-Ping Li / Zhao-Qian Liu / Ying Wang / Juan Chen / Jian Qu / Xiao-Jing Xu / Howard Lewis McLeod / Yi-Jing He / Kun Xia / Yuan-Wei Jia / Hong-Hao Zhou

    PLoS ONE, Vol 9, Iss 4, p e

    2014  Volume 96008

    Abstract: BACKGROUND: Over-expressed eukaryotic initiation factor 3a (eIF3a) in non-small cell lung cancer (NSCLC) contributed to cisplatin sensitivity. However, the role of eIF3a in oncogenesis was still controversial. This study was designed to investigate the ... ...

    Abstract BACKGROUND: Over-expressed eukaryotic initiation factor 3a (eIF3a) in non-small cell lung cancer (NSCLC) contributed to cisplatin sensitivity. However, the role of eIF3a in oncogenesis was still controversial. This study was designed to investigate the prognostic impact of eIF3a and p27 in radically resected NSCLC patients. METHODS: The expression levels of subcellular eIF3a and p27 were evaluated immunohistochemically in 537 radically resected NSCLC samples, and another cohort of 210 stage II NSCLC patients. Disease specific survival (DSS) and disease free survival (DFS) were analyzed by Kaplan-Meier method and Cox regression model. RESULTS: The subcellular expression of eIF3a was strongly correlated with status of p27 (Spearman rank coefficient correlation for cytoplasmic eIF3a and p27=0.653, for nuclear staining=0.716). Moreover, survival analysis revealed favorable prognostic impact of nuclear eIF3a, p27, and the combination high nuclear staining on NSCLC (Hazards Ratio=0.360, 95%CI=0.109-0.782, P=0.028). In addition, interaction research between biomarkers and chemotherapy status disclosed cisplatin-based regimen trend to prolong DSS of stage II NSCLC patients with high eIF3a-C (P=0.036)and low p27-N (P=0.031). CONCLUSIONS: Our findings suggested altered eIF3a expression closely correlated with p27 status, and the association was of prognostic value for resected NSCLC. Altered expression of eIF3a and p27 predicted prognosis of NSCLC independently.
    Keywords Medicine ; R ; Science ; Q
    Subject code 616
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top