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  1. Article ; Online: Typical Model and Mechanism Innovation of the Integrated Development of Litchi Culture and Tourism in Guangdong-Hong Kong-Macao Greater Bay Area

    Yongqi ZHAO / Junfen LIANG / Baizhan LEI / Canfang ZHOU / Xiaobo GONG

    Guangdong nongye kexue, Vol 50, Iss 1, Pp 82-

    2023  Volume 89

    Abstract: The integrated development of culture and tourism is one of the important ways for China to promote rural revitalization in the new era. Guangdong-Hong Kong-Macao Greater Bay Area uses the unique lychee cultural resources of the Lingnan region for ... ...

    Abstract The integrated development of culture and tourism is one of the important ways for China to promote rural revitalization in the new era. Guangdong-Hong Kong-Macao Greater Bay Area uses the unique lychee cultural resources of the Lingnan region for tourism development, and has formed many local experiences and typical models on the road of integrated development of culture and tourism. This paper summarized the development connotation of litchi cultural resources in Guangdong-Hong Kong-Macao Greater Bay Area. Based on the existing studies on the integration of lychee cultural tourism, from the perspective of industrial economy, the experience of the integrated development of lychee cultural tourism in the Greater Bay Area is divided into four typical models: the integrated development mode of popular science research, the integrated development mode of cultural festival, the integrated development mode of picking experience, and the integrated development mode of industry and tourism joint operation. Through in-depth analysis of the main characteristics of different modes and typical case practice, the specific path and industry dynamics of the integrated development of lychee cultural tourism in the Greater Bay Area were clarified. Finally, from the perspective of problems, it is proposed that the Greater Bay Area can carry out mechanism innovation in the following aspects, such as government role, platform construction and public participation, so as to promote the integration of lychee culture and tourism to achieve a unified development direction of social benefits, cultural benefits and economic benefits. For the first time, this paper makes a comprehensive interpretation of lychee cultural tour, which relies on local fruit cultural resources to design rural revitalization road. The research results can provide some enlightenment for other areas to implement rural revitalization integrated development of cultural tourism.
    Keywords lychee cultural tourism ; typical model ; mechanism innovation ; rural revitalization ; guangdong-hong kong -macao greater bay area ; Agriculture ; S
    Subject code 910
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Guangdong Academy of Agricultural Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Evolution of surface area and membrane shear modulus of matured human red blood cells during mechanical fatigue

    Qiaodong Wei / Xiaolong Wang / Ce Zhang / Ming Dao / Xiaobo Gong

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Volume 14

    Abstract: Abstract Mechanical properties of red blood cells (RBCs) change during their senescence which supports numerous physiological or pathological processes in circulatory systems by providing crucial cellular mechanical environments of hemodynamics. However, ...

    Abstract Abstract Mechanical properties of red blood cells (RBCs) change during their senescence which supports numerous physiological or pathological processes in circulatory systems by providing crucial cellular mechanical environments of hemodynamics. However, quantitative studies on the aging and variations of RBC properties are largely lacking. Herein, we investigate morphological changes, softening or stiffening of single RBCs during aging using an in vitro mechanical fatigue model. Using a microfluidic system with microtubes, RBCs are repeatedly subjected to stretch and relaxation as they squeeze into and out of a sudden contraction region. Geometric parameters and mechanical properties of healthy human RBCs are characterized systematically upon each mechanical loading cycle. Our experimental results identify three typical shape transformations of RBCs during mechanical fatigue, which are all strongly associated with the loss of surface area. We constructed mathematical models for the evolution of surface area and membrane shear modulus of single RBCs during mechanical fatigue, and quantitatively developed an ensemble parameter to evaluate the aging status of RBCs. This study provides not only a novel in vitro fatigue model for investigating the mechanical behavior of RBCs, but also an index closely related to the age and inherent physical properties for a quantitative differentiation of individual RBCs.
    Keywords Medicine ; R ; Science ; Q
    Subject code 669
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: KIF2C promotes clear cell renal cell carcinoma progression via activating JAK2/STAT3 signaling pathway

    Hao Deng / Xiaobo Gong / Guanghai Ji / Chenglong Li / Shaoping Cheng

    Molecular and Cellular Probes, Vol 72, Iss , Pp 101938- (2023)

    2023  

    Abstract: Background: Clear cell renal cell carcinoma (ccRCC) is one of the most common malignant tumors that can be highly aggressive. Despite advances in the exploration of its underlying molecular biology, the clinical outcome for advanced ccRCC is still ... ...

    Abstract Background: Clear cell renal cell carcinoma (ccRCC) is one of the most common malignant tumors that can be highly aggressive. Despite advances in the exploration of its underlying molecular biology, the clinical outcome for advanced ccRCC is still unsatisfied. Recently, more attention was paid to the functions of Kinesin family member 2C (KIF2C) in cancer progression, while the specific function of KIF2C in ccRCC has not been sufficiently elucidated. The present study aims to investigate the role of KIF2C in the progression of ccRCC and reveal potential mechanisms. Methods: Expression of KIF2C in ccRCC tissues and adjacent normal tissue was compared and the association of KIF2C expression level with tumor grade, stage, and metastasis were analyzed using online web tool. Kaplan-Meier survival was performed to detect the association of KIF2C expression and patient’ prognosis. Stably cell lines with KIF2C knockdown or overexpression were constructed by lentivirus infection. CCK-8, colony formation, scratch healing, and transwell invasion assays were carried out to explore the effect of KIF2C knockdown or overexpression on the proliferation, migration, and invasion of ccRCC cells. Gene set enrichment analysis (GSEA) was conducted to reveal signaling pathways associated with KIF2C expression. The effect of KIF2C on JAK2/STAT3 signaling pathway were explored by western blot assay. Results: KIF2C expression was significantly upregulated in ccRCC tissues and was higher with the increase of tumor grade, stage, and metastasis. Higher expression of KIF2C was correlated with worse overall survival and diseases free survival in ccRCC patients. Silence of KIF2C inhibited proliferation, migration, and invasion in ccRCC cells. Conversely, overexpression of KIF2C had the opposite effect. GSEA results showed that JAK/STAT signaling pathway was markedly enriched in KIF2Chigh group. Pearson’ correlation revealed that KIF2C expression was significantly associated with genes in JAK2/STAT3 signaling. Western blot results showed that ...
    Keywords ccRCC ; KIF2C ; JAK2/STAT3 signaling ; Progression ; Biology (General) ; QH301-705.5 ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Electro-active Variable-Stiffness Corrugated Structure Based on Shape-Memory Polymer Composite

    Xiaobo Gong / Fang Xie / Liwu Liu / Yanju Liu / Jinsong Leng

    Polymers, Vol 12, Iss 2, p

    2020  Volume 387

    Abstract: Shape-memory polymers (SMPs) can adjust their stiffness, lock a temporary shape, and recover the permanent shape upon an appropriate stimulus. They are applied in the field of morphing skins. This work presents a variable-stiffness corrugated sheet based ...

    Abstract Shape-memory polymers (SMPs) can adjust their stiffness, lock a temporary shape, and recover the permanent shape upon an appropriate stimulus. They are applied in the field of morphing skins. This work presents a variable-stiffness corrugated sheet based on a carbon fiber felt (CFF)-reinforced epoxy-based SMP composite that shows variable stiffness and extreme mechanical anisotropy for potential morphing skin applications. The corrugated sheet exhibits a variable stiffness with a change in temperature, which can help the skin adjust its stiffness according to different service environments. The corrugated sheet can be electrically heated rapidly and homogeneously due to its high electrical conductivity and enhanced heat transfer efficiency. Its Joule-heating effect acts as an effective active stimulation of the variable stiffness and shape-memory effect. The CFF-reinforced epoxy-based SMP composite was manufactured into a corrugated shape to obtain extreme mechanical anisotropy. The corrugated sheet shows a low in-plane stiffness to minimize the actuation energy, while it also possesses high out-of-plane stiffness to transfer the aerodynamic pressure load. Its mechanical properties, electrical heating performance, and shape-memory effect were investigated using experiments. The results show that the proposed SMP composite exhibits extreme mechanical anisotropy, considerable deformation ability, and variable stiffness induced by Joule heating without an external heater.
    Keywords shape-memory polymer ; shape-memory polymer composite ; corrugated structure ; morphing skin ; smp ; Organic chemistry ; QD241-441
    Subject code 621
    Language English
    Publishing date 2020-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: An

    Hong, Liu / Zhang, Wendy / Pan, Feibao / Xiaobo, Gong / Huang, Haoran / You, Yaqing / Deng, Lulu / Wang, Zhibiao / Zhang, Cai

    International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group

    2023  Volume 40, Issue 1, Page(s) 2251734

    Abstract: Objective: To observe the characteristics of a new extracorporeal high intensity focused ultrasound transducer, titled Haifu system JCQ-B, and to compare its safety and efficacy for breast ablation with the standard Haifu system JC transducer.: ... ...

    Abstract Objective: To observe the characteristics of a new extracorporeal high intensity focused ultrasound transducer, titled Haifu system JCQ-B, and to compare its safety and efficacy for breast ablation with the standard Haifu system JC transducer.
    Materials and methods: Ox liver with pig skin and pork ribs were prepared in a semi-sphere shape, served as
    Results: The BFR morphology of JCQ-B transducer was circular both
    Conclusions: The JCQ-B transducer improved the safety and efficacy of treatment by optimizing BFR morphology and ablation efficiency, which could be applied in the treatment of breast tumor.
    MeSH term(s) Female ; Animals ; Swine ; Humans ; High-Intensity Focused Ultrasound Ablation ; Liver/surgery ; Necrosis ; Transducers ; Breast Neoplasms
    Language English
    Publishing date 2023-08-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 632526-9
    ISSN 1464-5157 ; 0265-6736
    ISSN (online) 1464-5157
    ISSN 0265-6736
    DOI 10.1080/02656736.2023.2251734
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Selective Reduction of Nitrate into Nitrogen Using Cu/Fe Bimetal Combined with Sodium Sulfite

    Liu, Yanlan / Xiaobo Gong / Wenjing Yang / Bingqing Wang / Zhao Yang / Yong Liu

    Industrial & engineering chemistry process design and development. 2019 Mar. 14, v. 58, no. 13

    2019  

    Abstract: A novel two-step reduction process was constructed to removal nitrate selectively in aqueous solution. Nitrate was preliminarily reduced into nitrite with low yield of ammonia by microscale Cu/Fe bimetal, and then the accumulated nitrite was converted ... ...

    Abstract A novel two-step reduction process was constructed to removal nitrate selectively in aqueous solution. Nitrate was preliminarily reduced into nitrite with low yield of ammonia by microscale Cu/Fe bimetal, and then the accumulated nitrite was converted into N₂ by sodium sulfite. Cu was uniformly dispersed on the surface of Fe by a simple displacement reaction. Role of major iron components and fate of nitrogen species were investigated. The selectivity for N₂ was over 90%, and the yield of ammonia was below 10%. In the system, accumulation of nitrite resulted from the lower reduction rate of nitrite by Fe²⁺ in solution and the Cu/Fe coated by oxidized iron layer compared with the generation rate of nitrite via the reduction of nitrate. The generation of ammonia was caused by the reduction of nitrate/nitrite by Fe²⁺ adsorbed on the surface of oxidized iron layer coated on the bimetal at low reaction rate.
    Keywords ammonia ; aqueous solutions ; copper ; iron ; nitrates ; nitrites ; nitrogen ; oxidation ; process design ; sodium sulfite
    Language English
    Dates of publication 2019-0314
    Size p. 5175-5185.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 1484436-9
    ISSN 1520-5045 ; 0888-5885
    ISSN (online) 1520-5045
    ISSN 0888-5885
    DOI 10.1021/acs.iecr.8b05721
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Efficient in situ generation of H2O2 by novel magnesium–carbon nanotube composites

    Yang, Zhao / Bingqing Wang / Dan Yang / Tao Fu / Xiaobo Gong / Yong Liu

    RSC advances. 2018 Oct. 15, v. 8, no. 61

    2018  

    Abstract: Hydrogen peroxide (H2O2) is widely employed as an environmentally friendly chemical oxidant and an energy source. In this study, a novel magnesium–carbon nanotube composite was prepared by a ball milling process in argon atmosphere using polyvinylidene ... ...

    Abstract Hydrogen peroxide (H2O2) is widely employed as an environmentally friendly chemical oxidant and an energy source. In this study, a novel magnesium–carbon nanotube composite was prepared by a ball milling process in argon atmosphere using polyvinylidene fluoride (PVDF) as a binder. The resulting material was then tested for the in situ generation of H2O2. The preparation and operation conditions of the composite were systemically investigated and analyzed to improve the efficiency of the in situ generation of H2O2. Under the optimized conditions, while aerating with oxygen for 60 min, a maximum H2O2 concentration of 194.73 mg L−1 was achieved by the Mg–CNTs composite prepared using Mg : CNT : PVDF with a weight ratio of 5 : 1 : 2.4. In the Mg–CNTs/O2 system, dissolved oxygen molecules were reduced to H2O2, while magnesium was oxidized owing to the electrochemical corrosion. In addition, a part of dissolved magnesium ions converted into magnesium hydroxide and precipitated as nanoflakes on the surfaces of CNTs. A mechanism was proposed, suggesting that the formation of a magnesium/carbon nanotubes corrosion cell on the Mg–CNT composite promoted the in situ synthesis of H2O2. Overall, this study provides a promising and environmentally friendly strategy to fabricate magnesium/CNT composites for the in situ generation of H2O2, which could be applied in energy conversion and advanced oxidation processes for refractory wastewater treatment.
    Keywords argon (noble gases) ; carbon nanotubes ; corrosion ; dissolved magnesium ; electrochemistry ; energy conversion ; hydrogen peroxide ; ions ; magnesium hydroxide ; milling ; oxidants ; oxidation ; oxygen ; thermoplastics ; wastewater treatment
    Language English
    Dates of publication 2018-1015
    Size p. 35179-35186.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/c8ra05907a
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: Effects of accelerated aging on thermal, mechanical and shape memory properties of cyanate-based shape memory polymer: I vacuum ultraviolet radiation

    Xie, Fang / Liwu Liu / Xiaobo Gong / Longnan Huang / Jinsong Leng / Yanju Liu

    Polymer Degradation and Stability. 2017 Apr., v. 138

    2017  

    Abstract: Shape memory polymers (SMPs) are novel intelligent materials. Evaluation of the durability of SMPs in the complex environment of future space applications helps to optimize their incorporation in space-deployable structures. In this paper, we performed ... ...

    Abstract Shape memory polymers (SMPs) are novel intelligent materials. Evaluation of the durability of SMPs in the complex environment of future space applications helps to optimize their incorporation in space-deployable structures. In this paper, we performed vacuum outgassing and ultraviolet (UV) radiation exposure tests on a cyanate-based SMP with a glass transition temperature of 206 °C. The cyanate-based SMP shows 1.04% of total mass loss and 0.01% of collected volatile condensable matter, as determined by vacuum outgassing tests. Vacuum UV radiation deepened the color of the surface, shown little effect on the thermal stability of the SMP sample. The irradiation induced some instability of the molecular structure within the material, and this effect was gradually strengthened with the increase of exposure time. However, UV radiation did not detectably change the mechanical properties of the cyanate-based SMP; the tensile strength and elastic modulus remained essentially constant at 66 ± 2 MPa and 1940 ± 80 MPa, respectively. The average shape fixity rate and average shape recovery rate before and after UV radiation were all above 97.6%, and the repeatability was satisfactory.
    Keywords accelerated aging ; chemical structure ; color ; durability ; exposure duration ; glass transition temperature ; irradiation ; modulus of elasticity ; polymers ; tensile strength ; thermal stability ; ultraviolet radiation
    Language English
    Dates of publication 2017-04
    Size p. 91-97.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 1502217-1
    ISSN 0141-3910
    ISSN 0141-3910
    DOI 10.1016/j.polymdegradstab.2017.03.001
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: A case study of aggregation behaviors of titanium dioxide nanoparticles in the presence of dodecylbenzene sulfonate in natural water

    Du, Xin / Qiuru Wang / Shijie You / Xiaobo Gong / Xiuheng Wang

    Journal of Environmental Sciences. 2015 Oct. 01, v. 36

    2015  

    Abstract: The present work aims to ascertain the mechanisms of surfactant (dodecylbenzene sulfonate; DBS) effects on the aggregation behaviors of TiO2 nanoparticles (TiO2-NPs) in natural water samples. Aggregation experiments were conducted at a TiO2-NPs ... ...

    Abstract The present work aims to ascertain the mechanisms of surfactant (dodecylbenzene sulfonate; DBS) effects on the aggregation behaviors of TiO2 nanoparticles (TiO2-NPs) in natural water samples. Aggregation experiments were conducted at a TiO2-NPs concentration of 10mg/L in deionized water and in natural water samples via dynamic light scattering and Zeta potential determination. Average attachment efficiency was calculated to compare the aggregation behaviors of nanoparticles in the two aqueous media. Results showed that the effects of DBS on aggregation could be interpreted by both Derjaguin–Landau–Verwey–Overbeek (DLVO) and non-DLVO mechanisms. In natural water samples, aggregation did not occur rapidly and was able to develop slowly under all conditions, and the roles of DBS were obvious at high DBS concentration owing to the impacts of inherent components of natural water samples, such as colloids and natural organic compounds. Future aggregation studies should concentrate on multi-factor, multi-colloidal and dynamic aspects under similar environmental conditions.
    Keywords aggregation behavior ; case studies ; colloids ; environmental factors ; light scattering ; nanoparticles ; organic compounds ; surfactants ; titanium dioxide ; zeta potential
    Language English
    Dates of publication 2015-1001
    Size p. 84-92.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 1092300-7
    ISSN 1878-7320 ; 1001-0742
    ISSN (online) 1878-7320
    ISSN 1001-0742
    DOI 10.1016/j.jes.2015.05.011
    Database NAL-Catalogue (AGRICOLA)

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