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  1. Article ; Online: Viscosity Variations and Tribological Performances of Oleylamine-Modified Fe 3 O 4 Nanoparticles as Mineral Oil Additives

    Xiaoyu Wang / Huanchen Liu / Qilong Zhao / Xiaobo Wang / Wenjing Lou

    Lubricants, Vol 11, Iss 149, p

    2023  Volume 149

    Abstract: In order to improve the flowabilities and anti-friction and anti-wear properties of lubricants, the viscosity variations and tribological performances of oleylamine-modified Fe 3 O 4 nanoparticles as mineral oil additives were systematically investigated ...

    Abstract In order to improve the flowabilities and anti-friction and anti-wear properties of lubricants, the viscosity variations and tribological performances of oleylamine-modified Fe 3 O 4 nanoparticles as mineral oil additives were systematically investigated via rotational parallel plate rheometer, ball–disc reciprocating tribometer, non-contact three-dimensional surface profiler, scanning electron microscope, energy dispersive X-ray spectrometer and X-ray photoelectron spectroscopy. Spherical monodisperse Fe 3 O 4 nanoparticles were synthesized and dispersed into mineral oils to obtain lubricants with mass fractions of 1%, 3%, 5%, 8%, 10% and 20%, respectively. These lubricants have excellent stabilities within 12 months. Interestingly, the dynamic viscosity and kinematic viscosity of the lubricants first decrease and then increase with the increase in Fe 3 O 4 content, and the lubricants’ viscosity is at a minimum when the mass concentration is 5%. The tensile curves also show that with the mass fraction increase, the lubricants’ tackiness and adhesion have the same change law, and both reach the lowest point when the mass concentration is 5%. Meanwhile, Fe 3 O 4 nanoparticles can improve the tribological properties of the base oils. It is worth noting that the maximum reduction in the wear volume at 25 °C is up to 93.8% compared with base oils when the additive concentration of the Fe 3 O 4 nanoparticles is 5 wt%.
    Keywords oleylamine-modified Fe 3 O 4 nanoparticles ; high dispersion stability ; viscosity variations ; excellent tribological performances ; Science ; Q
    Subject code 290
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Generation and characterization of iPS cell line (SYSUSHi002-A) from PBMCs of an AML patient with TP53 mutation

    Lihua Yuan / Yaqun Wang / Rongli Xie / Dongjun Lin / Xiaobo Wang

    Stem Cell Research, Vol 73, Iss , Pp 103230- (2023)

    2023  

    Abstract: We have generated an iPSCs line (IPS-AML2-C3, SYSUSHi002-A) from AML cells of a 71-year-old male Acute Myeloid Leukaemia patient with TP53 gene mutation (TP53: c.824G > A, p.Cys275Tyr) using episomal plasmids encoding the factors OCT4, SOX2, KLF4, L-MYC ... ...

    Abstract We have generated an iPSCs line (IPS-AML2-C3, SYSUSHi002-A) from AML cells of a 71-year-old male Acute Myeloid Leukaemia patient with TP53 gene mutation (TP53: c.824G > A, p.Cys275Tyr) using episomal plasmids encoding the factors OCT4, SOX2, KLF4, L-MYC and human miR-302. The IPS-AML2-C3 (SYSUSHi002-A) iPSC line displayed typical embryonic stem cell-like morphology, carried the TP53 gene mutation, expressed several pluripotent stem cell makers, retained normal karyotype (46, XY), and was capable of forming three germ layer cells in vitro.
    Keywords Biology (General) ; QH301-705.5
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Diverse Roles of PUF Proteins in Germline Stem and Progenitor Cell Development in C. elegans

    Xiaobo Wang / Ekaterina Voronina

    Frontiers in Cell and Developmental Biology, Vol

    2020  Volume 8

    Abstract: Stem cell development depends on post-transcriptional regulation mediated by RNA-binding proteins (RBPs) (Zhang et al., 1997; Forbes and Lehmann, 1998; Okano et al., 2005; Ratti et al., 2006; Kwon et al., 2013). Pumilio and FBF (PUF) family RBPs are ... ...

    Abstract Stem cell development depends on post-transcriptional regulation mediated by RNA-binding proteins (RBPs) (Zhang et al., 1997; Forbes and Lehmann, 1998; Okano et al., 2005; Ratti et al., 2006; Kwon et al., 2013). Pumilio and FBF (PUF) family RBPs are highly conserved post-transcriptional regulators that are critical for stem cell maintenance (Wickens et al., 2002; Quenault et al., 2011). The RNA-binding domains of PUF proteins recognize a family of related sequence motifs in the target mRNAs, yet individual PUF proteins have clearly distinct biological functions (Lu et al., 2009; Wang et al., 2018). The C. elegans germline is a simple and powerful model system for analyzing regulation of stem cell development. Studies in C. elegans uncovered specific physiological roles for PUFs expressed in the germline stem cells ranging from control of proliferation and differentiation to regulation of the sperm/oocyte decision. Importantly, recent studies started to illuminate the mechanisms behind PUF functional divergence. This review summarizes the many roles of PUF-8, FBF-1, and FBF-2 in germline stem and progenitor cells (SPCs) and discusses the factors accounting for their distinct biological functions. PUF proteins are conserved in evolution, and insights into PUF-mediated regulation provided by the C. elegans model system are likely relevant for other organisms.
    Keywords germline ; C. elegans ; pumilio and fem-3-binding factor ; RNA regulation ; stem cells ; Biology (General) ; QH301-705.5
    Subject code 571
    Language English
    Publishing date 2020-02-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: An Attribute-Based Evaluation Framework for Sustainable Scientific Instruments Platforms

    Xiaobo Wang / Xueru Zhao / Caixia Zhang

    Sustainability, Vol 13, Iss 11842, p

    2021  Volume 11842

    Abstract: Scientific instrument platforms (SIPs) suffer from a lack of opinion and suggestions on sustainable operation management, leading to widely poor operation status nowadays. It is possible to guarantee the quality and efficiency of scientific and ... ...

    Abstract Scientific instrument platforms (SIPs) suffer from a lack of opinion and suggestions on sustainable operation management, leading to widely poor operation status nowadays. It is possible to guarantee the quality and efficiency of scientific and technological innovation activities and to improve the economic and social benefits of scientific and technological resources by constructing a framework system to promote the sustainability of the operation and management for SIPs. To meet the examination and evaluation requirements of the current operation and management of SIPs in China, this paper aims to establish an evaluation framework composed of indicators and attributes running through the construction and development of the SIPs from four aspects of learning and growth, process management, customers, and finance. Based on the existing research and operation practice, and according to the knowledge and preference of 627 SIP stakeholders, factor analysis has been adopted to extract and validate the hierarchical structure containing key sustainability indicators. The results show that the attribute characteristics of sustainable operating management for SIPs involve four significant dimensions of target positioning, team building, internal process control, and external service, among which the first and third ones have relatively higher priority. An effective and reliable evaluation tool is identified to be designed and provided for SIP operating management, which can also be used for self-evaluation and unified management of the sustainable operation of SIPs.
    Keywords scientific instrument platform ; operation and management ; factor analysis ; sustainability ; evaluation ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 650
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Cellular and Supracellular Planar Polarity

    Anna Popkova / Matteo Rauzi / Xiaobo Wang

    Frontiers in Cell and Developmental Biology, Vol

    A Multiscale Cue to Elongate the Drosophila Egg Chamber

    2021  Volume 9

    Abstract: Tissue elongation is known to be controlled by oriented cell division, elongation, migration and rearrangement. While these cellular processes have been extensively studied, new emerging supracellular mechanisms driving tissue extension have recently ... ...

    Abstract Tissue elongation is known to be controlled by oriented cell division, elongation, migration and rearrangement. While these cellular processes have been extensively studied, new emerging supracellular mechanisms driving tissue extension have recently been unveiled. Tissue rotation and actomyosin contractions have been shown to be key processes driving Drosophila egg chamber elongation. First, egg chamber rotation facilitates the dorsal-ventral alignment of the extracellular matrix and of the cell basal actin fibers. Both fiber-like structures form supracellular networks constraining the egg growth in a polarized fashion thus working as ‘molecular corsets’. Second, the supracellular actin fiber network, powered by myosin periodic oscillation, contracts anisotropically driving tissue extension along the egg anterior-posterior axis. During both processes, cellular and supracellular planar polarity provide a critical cue to control Drosophila egg chamber elongation. Here we review how different planar polarized networks are built, maintained and function at both cellular and supracellular levels in the Drosophila ovarian epithelium.
    Keywords tissue elongation ; planar cell polarity ; supracellular network ; tissue rotation ; actomyosin contractility ; Biology (General) ; QH301-705.5
    Subject code 571
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Estradiol attenuates LPS-induced acute lung injury via induction of aquaporins AQP1 and AQP5

    Xiaobo Wang / Xiuyun Zhou / Xiumei Xia / Yili Zhang

    European Journal of Inflammation, Vol

    2021  Volume 19

    Abstract: Background Acute lung injury (ALI) is associated with increased inflammation and oxidative stress. Estradiol is produced by the ovaries and is the most active hormone of estrogen. Our aim was to investigate whether estradiol contributes to protect ... ...

    Abstract Background Acute lung injury (ALI) is associated with increased inflammation and oxidative stress. Estradiol is produced by the ovaries and is the most active hormone of estrogen. Our aim was to investigate whether estradiol contributes to protect against lipopolysaccharide (LPS)-induced ALI via induction of aquaporins AQP1 and AQP5 and the underlying mechanisms. Methods and results For induction of ALI, LPS was applied once by intraperitoneal injection in SD rats 14 days after oophorectomy. To assess the therapeutic effects of estradiol on LPS-induced ALI, estradiol was subcutaneously injected for 1 h prior to LPS challenge. Estradiol can significantly attenuate the lung edema reflected by decreasing wet-to-dry weight ratio and permeability of lung and total protein concentration of bronchial lavage fluid (BALF). Results of histological detection showed that estradiol attenuated the lung injury reflected by reducing edema, congestion, and thickening pulmonary septal of lung tissues. In addition, estradiol attenuated TNF-α, IL-1β, and IL-6 and oxidative stress in lung tissues. Estradiol was more effective than estradiol associated with ERα antagonist or ERβ antagonist in protecting against LPS-induced ALI in rats. Mechanistically, we investigate whether estradiol regulates the expression of AQP1 and AQP5 in lung tissues. Of interest, estradiol upregulates AQP1 and AQP5 mRNA and protein expression. Taken together, these results demonstrate that estradiol can increase the expression of AQP1 and AQP5, which plays a critical role in ameliorating oxidative stress and downregulating inflammatory responses induced by LPS. Conclusion Therefore, these findings strongly suggest that AQP1 and AQP5 mediate the anti-inflammatory and antioxidant effects of estradiol.
    Keywords Medicine ; R
    Subject code 630
    Language English
    Publishing date 2021-09-01T00:00:00Z
    Publisher SAGE Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Application of Sustainable Development of Teaching in Engineering Education

    Fei Li / Jianfeng Jiang / Qingao Qin / Xiaobo Wang / Guoqiang Zeng / Yi Gu / Wentai Guo

    Sustainability, Vol 15, Iss 1782, p

    A Case Study of Undergraduate Course Design of Raman Spectroscopy Based on Virtual Reality (VR) Technology

    2023  Volume 1782

    Abstract: One of the core objectives of the Washington Agreement, the most influential international agreement on the mutual recognition of degrees in engineering education, is to ensure the continuous improvement of professional teaching. Education for ... ...

    Abstract One of the core objectives of the Washington Agreement, the most influential international agreement on the mutual recognition of degrees in engineering education, is to ensure the continuous improvement of professional teaching. Education for sustainable development is a vital direction of teaching reform and development of higher engineering education. Taking a Raman spectroscopy course as an example, this paper discusses VR-based course design and the strengths and limitations of a VR-based course. The idea of computational thinking and immersive learning is realized by introducing VR technology. Based on the research status in the field of Raman spectroscopy, the contents of 10 Raman spectroscopy courses are redesigned. Through a questionnaire survey, peer review, and interview, the rationality of the course design is evaluated, and based on this, a feedback mechanism is established to ensure the continuous improvement of the course. Eventually, the advantages and disadvantages of the new curriculum are evaluated, and the development direction and limitations of the corresponding teaching model are put forward. According to the research, although 85% of the students said that it is difficult to accept the VR-based course at short notice, 90% and more of the students recognize this new teaching model. They believe that the VR-based course changes their traditional learning habits and helps cultivate self-learning ability. The research results can be utilized as a crucial reference for engineering education reform and provide a reliable model for the sustainable development of education.
    Keywords sustainable development of education ; curriculum design ; Raman spectroscopy ; VR technology ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 370
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: In‐situ Construction of CNTs Decorated Titanium Carbide on Ti Mesh Towards the Synergetic Improvement of Energy Storage Properties for Aqueous Zinc Ion Capacitors

    Dr. Hai Wang / Prof. Jinxia Huang / Xiaobo Wang / Prof. Zhiguang Guo / Weimin Liu

    ChemElectroChem, Vol 10, Iss 19, Pp n/a-n/a (2023)

    2023  

    Abstract: Abstract The development of aqueous zinc‐ion capacitors (ZICs) is an effective approach to improve the safety and environmental friendliness of energy storage devices. In this paper, TiC/CNTs core‐shell array structures (TCT) were synthesized on titanium ...

    Abstract Abstract The development of aqueous zinc‐ion capacitors (ZICs) is an effective approach to improve the safety and environmental friendliness of energy storage devices. In this paper, TiC/CNTs core‐shell array structures (TCT) were synthesized on titanium substrate through in‐situ simple chemical vapor deposition and carbon reduction and used as self‐supporting cathodes for aqueous ZICs. As expected, as‐prepared TCT electrode exhibited excellent electrochemical performance in aqueous electrolytes, demonstrating a high specific capacitance of 275.13 F g−1 at a current density of 1.0 A g−1 and maintaining 90.5 % of its initial capacity after 10000 charge‐discharge cycles. The assembled Zn//TCT ZIC displays excellent rate capability, delivering an excellent specific capacitance of 298.2 F g−1 at 0.5 A g−1 and 193.5 F g−1 at a high current density of 10 A g−1. Zn//TCT device can provide an ultra‐high energy density of 24.8 Wh kg−1 at a power of 6984.1 W kg−1. DFT calculations further demonstrate that a large number of electrons are transferred at the TiC/CNT interface and stable TIC−C bonds can be formed. This work provides a new strategy for rationally designing transition metal carbide electrodes and constructing ZICs with high energy and power densities.
    Keywords Electrode material ; First principles ; TiC ; Self-supporting ; Zinc ion capacitor ; Industrial electrochemistry ; TP250-261 ; Chemistry ; QD1-999
    Subject code 541 ; 620
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher Wiley-VCH
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: The Impact of Water on the Tribological Behavior of Lubricating Grease Based on Calcium Carbonate Polymorphs

    Longqi Sun / Rui Ma / Qin Zhao / Gaiqing Zhao / Xiaobo Wang

    Lubricants, Vol 10, Iss 8, p

    2022  Volume 188

    Abstract: In this article, calcium sulfonate complex grease with different polymorphs was acquired. With reference to the improved rolling stability test method, 5% and 10% water were added to the calcium sulfonate composite grease respectively. The influence of ... ...

    Abstract In this article, calcium sulfonate complex grease with different polymorphs was acquired. With reference to the improved rolling stability test method, 5% and 10% water were added to the calcium sulfonate composite grease respectively. The influence of water on the flow and deformation characteristics of grease under external force was characterized by rheological analysis. Moreover, the influence of water on the tribological behaviors of grease was evaluated at 30 and 80 °C. The results indicate that water could affect the flow and deformation characteristics of calcium sulfonate complex grease in vaterite polymorph (CSCG-V) more than calcium sulfonate complex grease in calcite polymorph (CSCG-C), and CSCG-V could combine with water to form a more stable grease under external force. Tribological results also clearly show that CSCG-C with water shows better tribological properties than CSCG-V with water under harsh conditions. There was no significant difference in the components of the films that consisted of CaCO 3 and CaO regardless of grease within or without water. The improvement of tribological properties of CSCG-C with 5% and 10% water benefited from the influence of water on the film forming capacity of calcium carbonate on the steel surface.
    Keywords calcium sulfonate complex grease ; water influence ; rheological analysis ; tribological behaviors ; Science ; Q
    Subject code 500
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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