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  1. AU="Xiaofang Li"
  2. AU="Campbell, John D"
  3. AU="Emara, Yasmine"
  4. AU="Orbe, Paul"
  5. AU="Karel J van Erpecum"
  6. AU=Oltean Mihai
  7. AU="Relph, Katharine A"
  8. AU=Li Jifen AU=Li Jifen
  9. AU="Diamant, Eran"
  10. AU="Kyoung, Henry" AU="Kyoung, Henry"
  11. AU=al-Gazali L I
  12. AU="Maillet, Jean-Michel"
  13. AU="Enlong Liu"
  14. AU="Afria, Dikshant"
  15. AU="Duggal, M. S."
  16. AU="Narcisa G. Pricope"
  17. AU="Kunisada, Toshiyuki"
  18. AU="Barvkar, Vitthal"

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  1. Artikel ; Online: Metagenome-assembled genomes infer potential microbial metabolism in alkaline sulphidic tailings

    Wenjun Li / Xiaofang Li

    Environmental Microbiome, Vol 16, Iss 1, Pp 1-

    2021  Band 10

    Abstract: Abstract Background Mine tailings are hostile environment. It has been well documented that several microbes can inhabit such environment, and metagenomic reconstruction has successfully pinpointed their activities and community structure in acidic ... ...

    Abstract Abstract Background Mine tailings are hostile environment. It has been well documented that several microbes can inhabit such environment, and metagenomic reconstruction has successfully pinpointed their activities and community structure in acidic tailings environments. We still know little about the microbial metabolic capacities of alkaline sulphidic environment where microbial processes are critically important for the revegetation. Microbial communities therein may not only provide soil functions, but also ameliorate the environment stresses for plants’ survival. Results In this study, we detected a considerable amount of viable bacterial and archaeal cells using fluorescent in situ hybridization in alkaline sulphidic tailings from Mt Isa, Queensland. By taking advantage of high-throughput sequencing and up-to-date metagenomic binning technology, we reconstructed the microbial community structure and potential coupled iron and nitrogen metabolism pathways in the tailings. Assembly of 10 metagenome-assembled genomes (MAGs), with 5 nearly complete, was achieved. From this, detailed insights into the community metabolic capabilities was derived. Dominant microbial species were seen to possess powerful resistance systems for osmotic, metal and oxidative stresses. Additionally, these community members had metabolic capabilities for sulphide oxidation, for causing increased salinity and metal release, and for leading to N depletion. Conclusions Here our results show that a considerable amount of microbial cells inhabit the mine tailings, who possess a variety of genes for stress response. Metabolic reconstruction infers that the microbial consortia may actively accelerate the sulphide weathering and N depletion therein.
    Schlagwörter Sulphidic tailings ; Metagenomics ; Binning ; Community genomics ; Sulphide oxidation ; Environmental sciences ; GE1-350 ; Microbiology ; QR1-502
    Sprache Englisch
    Erscheinungsdatum 2021-04-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Seborrheic dermatitis-like adult tinea capitis due to Trichophyton rubrum in an elderly man

    Wenting Xie / Yuping Chen / Weida Liu / Xiaofang Li / Guanzhao Liang

    Medical Mycology Case Reports, Vol 41, Iss , Pp 16-

    2023  Band 19

    Abstract: Adult tinea capitis is often neglected and misdiagnosed, especially in men. We herein reported an older man with seborrheic dermatitis-like tinea capitis caused by Trichophyton rubrum to raise awareness of the disease. Scale and alopecia were the ... ...

    Abstract Adult tinea capitis is often neglected and misdiagnosed, especially in men. We herein reported an older man with seborrheic dermatitis-like tinea capitis caused by Trichophyton rubrum to raise awareness of the disease. Scale and alopecia were the critical diagnostic clues in this patient. Given the previous presence of tinea pedis and onychomycosis, relevant mycological examinations were promptly performed, and antifungal therapy, as well as patient education, were effectively administered.
    Schlagwörter Adult tinea capitis ; Trichophyton rubrum ; Epidemiology ; Mycological examinations ; Diagnosis ; Medicine (General) ; R5-920 ; Biology (General) ; QH301-705.5
    Sprache Englisch
    Erscheinungsdatum 2023-09-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Effectiveness of social support programmes on loneliness in community-dwelling older adults

    Li Yao / Tingting Ren / Xiaofang Li / Yinhua Wang / Tingshu Wang

    BMJ Open, Vol 13, Iss

    study protocol for a meta-analysis of randomised controlled trials

    2023  Band 12

    Abstract: Background The prevalence of loneliness among older adults is of great importance in the field of public health. Numerous studies have provided evidence supporting the effectiveness of social support as a powerful intervention for reducing loneliness in ... ...

    Abstract Background The prevalence of loneliness among older adults is of great importance in the field of public health. Numerous studies have provided evidence supporting the effectiveness of social support as a powerful intervention for reducing loneliness in older individuals. However, the specific types of social support that yield positive results are yet to be determined. Therefore, this study aims to conduct a comprehensive review to compare and analyse the effectiveness of different support mechanisms in alleviating loneliness among community-dwelling older adults.Methods and analysis A thorough search will be conducted on various electronic databases, including EMBASE, PubMed, the Cochrane Library, Web of Science, PsycINFO, Scopus, Google Scholar, China National Knowledge Infrastructure Library, China Science and Technology Journal Database (Weipu), WanFang Database, and China Biology Medicine Disc. The search will include randomised controlled trials published in English or Chinese that focus on interventions for loneliness in older individuals, with loneliness as the primary measure of interest. The selection and choice of articles will be the responsibility of both reviewers. The JBI Critical Appraisal Checklist for Randomised Controlled Trials will be used to assess the methodological quality of the included trials. When sufficient data are obtained and the study is relatively homogeneous, a random-effects or fixed-effects model will be employed to conduct a meta-analysis, yielding a descriptive synthesis of the findings.Ethics and dissemination Ethics approval will not be sought for this systematic review as it will exclusively focus on published papers. The review findings will be showcased at a conference dedicated to this specific field and published in an appropriate journal that undergoes peer evaluation.PROSPERO registration number CRD42020226523.
    Schlagwörter Medicine ; R
    Thema/Rubrik (Code) 028
    Sprache Englisch
    Erscheinungsdatum 2023-12-01T00:00:00Z
    Verlag BMJ Publishing Group
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Video Satellite Imagery Super-Resolution via Model-Based Deep Neural Networks

    Zhi He / Xiaofang Li / Rongning Qu

    Remote Sensing, Vol 14, Iss 749, p

    2022  Band 749

    Abstract: Video satellite imagery has become a hot research topic in Earth observation due to its ability to capture dynamic information. However, its high temporal resolution comes at the expense of spatial resolution. In recent years, deep learning (DL) based ... ...

    Abstract Video satellite imagery has become a hot research topic in Earth observation due to its ability to capture dynamic information. However, its high temporal resolution comes at the expense of spatial resolution. In recent years, deep learning (DL) based super-resolution (SR) methods have played an essential role to improve the spatial resolution of video satellite images. Instead of fully considering the degradation process, most existing DL-based methods attempt to learn the relationship between low-resolution (LR) satellite video frames and their corresponding high-resolution (HR) ones. In this paper, we propose model-based deep neural networks for video satellite imagery SR (VSSR). The VSSR is composed of three main modules: degradation estimation module, intermediate image generation module, and multi-frame feature fusion module. First, the blur kernel and noise level of LR video frames are flexibly estimated by the degradation estimation module. Second, an intermediate image generation module is proposed to iteratively solve two optimal subproblems and the outputs of this module are intermediate SR frames. Third, a three-dimensional (3D) feature fusion subnetwork is leveraged to fuse the features from multiple video frames. Different from previous video satellite SR methods, the proposed VSSR is a multi-frame-based method that can merge the advantages of both learning-based and model-based methods. Experiments on real-world Jilin-1 and OVS-1 video satellite images have been conducted and the SR results demonstrate that the proposed VSSR achieves superior visual effects and quantitative performance compared with the state-of-the-art methods.
    Schlagwörter video satellite imagery ; super-resolution ; deep learning ; Science ; Q
    Thema/Rubrik (Code) 629
    Sprache Englisch
    Erscheinungsdatum 2022-02-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: Impact of Tillage and Straw Treatment Methods on Rice Growth and Yields in a Rice–Ratoon Rice Cropping System

    Shengchun Li / Yilin Zhang / Lihao Guo / Xiaofang Li

    Sustainability, Vol 14, Iss 9290, p

    2022  Band 9290

    Abstract: The rice–ratoon rice cropping system has the advantages of saving labor and imparting economic benefits. Optimizing tillage and straw management is beneficial for improving ratoon rice growth and yield. In this study, field experiments were conducted to ... ...

    Abstract The rice–ratoon rice cropping system has the advantages of saving labor and imparting economic benefits. Optimizing tillage and straw management is beneficial for improving ratoon rice growth and yield. In this study, field experiments were conducted to examine the effects of four tillage and straw managements on the growth and yield of a rice–ratoon rice cropping system in central China in 2020 to 2021. The managements included no-till with main-season and ratoon-season rice residues retained on the soil’s surface (NT+S), plow tillage with residue retention (CT+S), no-till with residues removed (NT-S), and plow tillage with residues removed (CT-S). Compared to NT, CT significantly increased yield by 33.70% and 29.12% in the main and ratoon seasons, respectively. Compared to straw removal, straw returning significantly increased yield by 13.37% and 27.29% in the main and ratoon seasons, respectively. In general, both CT and straw returning improved root function (root activity and root dry weight) and photosynthetic capacity (leaf area index, net photosynthetic rate, and leaf chlorophyll content). CT combined with straw returning was able to achieve the highest annual rice yield.
    Schlagwörter plow tillage ; straw removing ; ratoon rice ; root function ; photosynthetic capacity ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 580
    Sprache Englisch
    Erscheinungsdatum 2022-07-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Effects of Baicalin on Alopecia and the Associated Mechanism

    Liping Chen / Bo Fan / Huan Gu / Liuqing Yang / Xiaofang Li

    BioMed Research International, Vol

    2022  Band 2022

    Abstract: The aim of the present study was to explore the potential pharmacological mechanism of baicalin by combining network pharmacology prediction and the experimental verification of alopecia. Networks of baicalin-associated targets and alopecia-related genes ...

    Abstract The aim of the present study was to explore the potential pharmacological mechanism of baicalin by combining network pharmacology prediction and the experimental verification of alopecia. Networks of baicalin-associated targets and alopecia-related genes were constructed using the STRING database. Potential targets and pathways associated with the therapeutic efficacy of baicalin were identified via enrichment analysis using Cytoscape and the database for annotation, visualization and integrated discovery (Metascape). The back hair of C57BL/6J mice was removed with depilatory cream to verify the therapeutic effect of baicalin. Human hair dermal papilla cells (HHDPCs) were used to explore the mechanism of action of baicalin. Network pharmacology analysis revealed that the potential targets of baicalin mainly include protein serine/threonine kinase, Src protein, epidermal growth factor receptor, and insulin-like growth factor 1 (IGF1), which were indicated to mediate neutrophil degranulation and regulation of cell-cell adhesion, vesicle lumen, cytoplasmic vesicle, membrane raft, and endopeptidase activity. Multiple pathways were identified, such as proteoglycans in cancer, PI3K/AKT, and forkhead box O signaling pathways. Following baicalin treatment for the experimental mice, the coverage, length, and weight of the hair increased in a baicalin dose-dependent manner. Moreover, the histological evaluation showed that the number of hair follicles increased after baicalin treatment and melanin formation were pronounced. In addition, baicalin induced an increase in the phosphorylated p-AKT, p-glycogen synthase kinase-3β, p-PI3K, TGF-β1, and vascular endothelial growth factor levels. Furthermore, the activation levels of key protein p-AKT were increased. Baicalin induced the proliferation of HHDPCs in vitro and significantly upregulated p-AKT, IGF1, and alkaline phosphatase. In conclusion, the present study revealed that the pharmacological mechanisms of baicalin in alopecia therapy were associated with the ...
    Schlagwörter Medicine ; R
    Thema/Rubrik (Code) 500
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag Hindawi Limited
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: Editorial

    Likun Wang / Nina Kamennaya / Michael F. Cohen / Xiaofang Li

    Frontiers in Environmental Science, Vol

    Highlighting the Role of Microbes in Greener Wastewater Treatment

    2022  Band 10

    Schlagwörter microbes ; wastewater ; treatment ; biotechnology ; pollution ; Environmental sciences ; GE1-350
    Sprache Englisch
    Erscheinungsdatum 2022-04-01T00:00:00Z
    Verlag Frontiers Media S.A.
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Effects of Berberine on glucolipid metabolism among dehydroepiandrosterone-induced rats of polycystic ovary syndrome with insulin-resistance

    Li Li / Yao Xiao / Jiahe Zhou / Hui Mo / Xiaofang Li / Yuancheng Li / Youfeng Wang / Minglin Zhong

    Heliyon, Vol 10, Iss 2, Pp e24338- (2024)

    2024  

    Abstract: Polycystic ovary syndrome (PCOS) is a set of endocrine disorder syndrome characterized by ovulation disorder. Increased insulin resistance (IR) and compensatory hyperinsulinemia play a vital role in the pathogenesis of PCOS. Therefore, insulin ... ...

    Abstract Polycystic ovary syndrome (PCOS) is a set of endocrine disorder syndrome characterized by ovulation disorder. Increased insulin resistance (IR) and compensatory hyperinsulinemia play a vital role in the pathogenesis of PCOS. Therefore, insulin sensitizing agents have been studied in the treatment of PCOS. Berberine (BBR) has been proved to alleviate IR in patients with PCOS, but the mechanism remained unclear. This study was aimed to verify the regulatory mechanism of BBR on PCOS-IR rats. Firstly, we established a female rat PCOS-IR model induced by dehydroepiandrosterone (DHEA) and found that estrus cycle was disrupted in the PCOS-IR group, serum fasting insulin (FINS) level and the homeostasis model assessment of insulin resistance (HOMA-IR) index were significantly higher than normal control group. BBR treatment could recover estrous cycle, reduce abnormal serum hormone levels like luteotropic hormone (LH) and testosterone (T). Most importantly, BBR could concentration-dependently reduce serum FINS level in PCOS-IR rat model. Meanwhile, BBR may improve the abnormal lipid metabolism levels in PCOS-IR group by decreasing low density lipoprotein (LDL), total cholesterol (TC) and triglyceride (TG). Histological results showed that BBR can also protect normal histological structures of ovaries in PCOS-IR rats. Our results indicated that BBR plays a protective role in PCOS-IR, increasing insulin sensitivity, improving hyperandrogens and recovering abnormal blood lipids. Therefore, Our research provides novel insights for therapeutic treatment of BBR in patients with glucolipid metabolic disturbances.
    Schlagwörter Polycystic ovary syndrome (PCOS) ; Insulin resistance (IR) ; Berberine (BBR) ; Glucolipid metabolism ; PI3K-Akt signaling pathway ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2024-01-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel: Influence of peasant household differentiation and risk perception on soil and water conservation tillage technology adoption- an analysis of moderating effects based on government subsidies

    Li, Liu / Dingyi, Shangguan / Xiaofang, Li / Zhide, Jiang

    Journal of cleaner production. 2021 Mar. 15, v. 288

    2021  

    Abstract: In this paper, we comprehensively assess the differences in soil and water conservation tillage technology among different districts: Fenyang and Ji county of Shanxi province, Ansai and Jingbian county of Shaanxi province, and Zhenyuan and Jingchuan ... ...

    Abstract In this paper, we comprehensively assess the differences in soil and water conservation tillage technology among different districts: Fenyang and Ji county of Shanxi province, Ansai and Jingbian county of Shaanxi province, and Zhenyuan and Jingchuan county in Gansu province. We use survey data of 1237 rural households of the Loess Plateau on their adoption of the core technology of soil and water conservation tillage (e.g., contour tillage, groove ridge planting, moderate or non-tillage, subsoiling, straw plowing, stubble mulching, plastic film covering). We use the bootstrap test to analyze peasant household horizontal and vertical differentiation directly impacting on soil and water conservation tillage technology adoption. Next, we test risk perception as the mediation role for technology adoption. Finally, we analyze the moderating effect of government subsidies, and government subsidy can compensate for possible risk losses and encourage farmers to adopt soil and water conservation tillage technology. The results are showed the following: (1) The horizontal and vertical differentiation of farmers have a significant positive impact on the adoption of soil and water conservation tillage technology. (2) In the context of horizontal differentiation, risk perception has a positive mediating effect on the adoption of contour tillage, groove ridge planting, moderate or non-tillage, straw plowing, and plastic film covering technology; in the adoption of subsoiling technology, the mediating effect of risk perception differs because of the size of the government subsidies; in the adoption of stubble mulching technology, the mediating effect of risk perception is not significant. In the context of vertical differentiation, risk perception has a positive mediating effect in the adoption of contour tillage, groove ridge planting and straw plowing; and in the adoption of moderate or non-tillage, subsoiling, and stubble mulching, the mediating effect of risk perception is not significant. (3) In the context of horizontal differentiation, the moderating effect of government subsidies is not significant in the adoption of contour tillage, moderate or non-tillage, straw plowing, and plastic film covering; the moderating effect of government subsidies is significant in the adoption of groove ridge planting and subsoiling. In the context of vertical differentiation, the moderating effect of a government subsidies is not significant in the adoption of contour tillage, groove ridge planting, and straw plowing technology; the moderating effect of a government subsidies is significant in the application of plastic film covering technology.
    Schlagwörter conservation tillage ; farmers ; households ; innovation adoption ; paper ; peasantry ; plastic film ; plowing ; ridge planting ; risk perception ; soil ; straw ; stubble mulching ; subsidies ; subsoiling ; surveys ; water conservation ; China
    Sprache Englisch
    Erscheinungsverlauf 2021-0315
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel
    Anmerkung NAL-light
    ISSN 0959-6526
    DOI 10.1016/j.jclepro.2020.125092
    Datenquelle NAL Katalog (AGRICOLA)

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  10. Artikel ; Online: Widespread bacterial responses and their mechanism of bacterial metallogenic detoxification under high concentrations of heavy metals

    Xiaofang Li / Menglin Sun / Luting Zhang / Roger D. Finlay / Renlu Liu / Bin Lian

    Ecotoxicology and Environmental Safety, Vol 246, Iss , Pp 114193- (2022)

    2022  

    Abstract: Microbial mineralization is increasingly used in bioremediation of heavy metal pollution, but better mechanistic understanding of the processes involved and how they are regulated are required to improve the practical application of microorganisms in ... ...

    Abstract Microbial mineralization is increasingly used in bioremediation of heavy metal pollution, but better mechanistic understanding of the processes involved and how they are regulated are required to improve the practical application of microorganisms in bioremediation. We used a combination of morphological (TEM) and analytical (XRD, XPS, FTIR) methods, together with novel proteomic analyses, to investigate the detoxification mechanisms, used by a range of bacteria, including the strains Bacillus velezensis LB002, Escherichia coli DH5α, B. subtilis 168, Pseudomonas putida KT2440, and B. licheniformis MT-1, exposed to elevated concentrations of Cd2+ and combinations of Cd2+, Pb2+, Cu2+, and Zn2+, in the presence and absence of added CaCl2. Common features of detoxification included biomineralization, including the production of biological vaterite, up-regulation of proteins involved in flagellar movement and chemotaxis, biofilm synthesis, transmembrane transport of small molecules and organic matter decomposition. The putative roles of differentially expressed proteins in detoxification are discussed in relation to chemical and morphological data and together provide important tools to improve screening, selection, and practical application of bacterial isolates in bioremediation of polluted environments.
    Schlagwörter Metallogenic detoxification ; Heavy metal ; Microbial remediation ; Proteomics ; Molecular mechanism ; Environmental pollution ; TD172-193.5 ; Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 333
    Sprache Englisch
    Erscheinungsdatum 2022-11-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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