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  1. AU="Xiaofang Zhang"
  2. AU=Stincarelli Maria Alfreda AU=Stincarelli Maria Alfreda
  3. AU="McNabb, Warren C."
  4. AU="Seker, Demet"
  5. AU="Braman, Sidney S"
  6. AU="Yerke, Lisa"
  7. AU="Antonella Lettieri"
  8. AU="Valdiviezo, Jesús"

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  1. Artikel ; Online: Investigation of personal data protection mechanism based on blockchain technology

    Rongrong Zhu / Maofeng Wang / Xiaofang Zhang / Xinyun Peng

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Band 18

    Abstract: Abstract Blockchain technology is increasingly being used in personal data protection. Inspired by the importance of data security, this paper proposes a personal data protection mechanism based on blockchain, combined with distributed hash tables and ... ...

    Abstract Abstract Blockchain technology is increasingly being used in personal data protection. Inspired by the importance of data security, this paper proposes a personal data protection mechanism based on blockchain, combined with distributed hash tables and cryptography, to enhance users' control over the data generated using web applications. This paper designs this mechanism's system model and describes the three aspects in detail: data storage mechanism, data encryption mechanism, and data trading mechanism. Among them, the data storage mechanism restricts user data to be stored only in the local storage space of the user terminal, the decentralized blockchain network, and the distributed hash table network to ensure that enterprises providing network applications cannot privately store user interaction data, the encryption mechanism is responsible for encrypting all user data recorded in the network and allows users to control the key of the data to ensure the security of the user data in the blockchain and distributed hash tables, the data transaction mechanism allows users to trade their data, and to incentivize enterprises to assist users in collecting personal data, data transaction contracts are built into the data transaction mechanism, allowing enterprises to receive a share of the revenue from user data transactions. Then, for data transactions, use the Stackelberg game to simulate the revenue sharing between users and service providers in data trading to incentivize enterprises providing web services to assist users in collecting their data. The simulation results show that when the number of users is 1000, the revenues of this scheme for service providers are 31%, 561%, and 19% higher than the existing scheme. Finally, the personal data protection platform is implemented by code to verify the feasibility of the theory proposed in this paper in personal data protection.
    Schlagwörter Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 005 ; 303
    Sprache Englisch
    Erscheinungsdatum 2023-12-01T00:00:00Z
    Verlag Nature Portfolio
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Spatial Spillover Effects of Resource Misallocation on the Green Total Factor Productivity in Chinese Agriculture

    Jiangfeng Hu / Xiaofang Zhang / Tingting Wang

    International Journal of Environmental Research and Public Health, Vol 19, Iss 15718, p

    2022  Band 15718

    Abstract: Continuous resource misallocation not only results in total factor productivity loss but also leads to ecological degradation. Therefore, in the process of changing from extensive growth to intensive growth, Chinese agriculture should pay attention to ... ...

    Abstract Continuous resource misallocation not only results in total factor productivity loss but also leads to ecological degradation. Therefore, in the process of changing from extensive growth to intensive growth, Chinese agriculture should pay attention to the problem of resource misallocation. There is currently a lack of relevant research, especially concerning the spatial spillover effects of resource misallocation at the city level. To fill this gap, we employ a spatial panel model for empirical testing on the basis of measuring agricultural green total factor productivity (GTFP) in 306 cities in China from 1996–2017. We found that there is positive spatial autocorrelation in Chinese agricultural GTFP, but it decreases year by year. Misallocation in land, labor, machinery and fertilizer all directly hinder the local GTFP. The eastern is mainly negatively affected by neighbor resource misallocation, while the central and western are mainly negatively affected by local resource misallocation. Finally, the indirect effect of neighbor resource misallocation on GTFP gradually shifts from inhibiting effect to a facilitating effect with increasing spatial distance. These findings have clear policy implications: Chinese government should strengthen agricultural green technology innovation and diffusion, strengthen environmental regulation and promote the free movement of labor between regions and sectors.
    Schlagwörter agricultural economics ; resource misallocation ; green total factor productivity ; sequential DEA ; spatial panel model ; Medicine ; R
    Sprache Englisch
    Erscheinungsdatum 2022-11-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: LncRNA HOTAIR promotes the proliferation and invasion/metastasis of breast cancer cells by targeting the miR-130a-3p/Suv39H1 axis

    Wenxing He / Dongmei Li / Xiaofang Zhang

    Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101279- (2022)

    2022  

    Abstract: Long noncoding RNAs (lncRNAs) are a group of transcripts, more than 200 bp in size and regulate cell proliferation, differentiation and apoptosis. LncRNA HOX Transcript Antisense Intergenic RNA (HOTAIR) promotes tumor progression and increases cancer ... ...

    Abstract Long noncoding RNAs (lncRNAs) are a group of transcripts, more than 200 bp in size and regulate cell proliferation, differentiation and apoptosis. LncRNA HOX Transcript Antisense Intergenic RNA (HOTAIR) promotes tumor progression and increases cancer susceptibility by regulating microRNA expression and function. HOTAIR regulates miR-130a-3p expression in hepatocellular carcinoma cells. Bioinformatics analysis revealed that Suv39H1 contained a putative binding site for miR-130a-3p. We speculate that LncRNA HOTAIR promotes the proliferation and invasion/metastasis of breast cancer (BC) cells by targeting the miR-130a-3p/Suv39H1 axis. High HOTAIR expression facilitated BC cell growth and metastasis. HOTAIR functioned as a ceRNA by sponging miR-130a-3p and subsequently promoted Suv39H1-mediated AKT/mTOR signaling. Suv39H1 restoration abolished the effects of HOTAIR knockdown on BC cell growth and metastasis. HOTAIR facilitated the Suv39H1-mediated AKT/mTOR pathway by acting as a molecular sponge of miR-130a-3p.Our results provide a better understanding of the interactions of HOTAIR and miR-103a-3p/Suv39H1 in BC and a potential prognostic biomarker and therapeutic target for BC.
    Schlagwörter Breast cancer ; LncRNA HOTAIR ; MiR-130a-3p ; Suv39H1 ; Metastasis ; Biology (General) ; QH301-705.5 ; Biochemistry ; QD415-436
    Thema/Rubrik (Code) 500
    Sprache Englisch
    Erscheinungsdatum 2022-07-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Exploring Minimum Secondary Injury for the Treatment of Ocular Trauma With Giant Intraocular Foreign Bodies

    Jing Ma / Xiaofang Zhang / Xuemin Jin / Wenzhan Wang

    Frontiers in Medicine, Vol

    2022  Band 8

    Abstract: PurposeTo investigate the clinical therapy for giant intraocular foreign bodies (IOFBs) and evaluate the best treatment method with minimum secondary injury.MethodsWe retrospectively analyzed the data of 73 eyes of 73 patients with ocular trauma caused ... ...

    Abstract PurposeTo investigate the clinical therapy for giant intraocular foreign bodies (IOFBs) and evaluate the best treatment method with minimum secondary injury.MethodsWe retrospectively analyzed the data of 73 eyes of 73 patients with ocular trauma caused by giant IOFBs between January 2016 and December 2018. The IOFB size, localization, shape, and magnetic properties were recorded. The best corrected visual acuity (BCVA), ocular tissue injuries, entrance wound, interval time from injury to second phase surgery, silicone oil removal, and globe recovery were also observed. The cases were divided into three groups based on the following IOFB extraction paths: limbus path, the pars plana path, and the entrance wound path. The BCVA, IOFB size and shape, the wound, endophthalmitis, and silicone oil removal were compared among the three groups.ResultsThe IOFBs were 46 cases of magnetic and 27 cases of nonmagnetic, with a shape of thin flat in 19 cases, thick flat in 12 cases, long in seven cases, and irregular in 35 cases. Multiple damages were caused by the giant IOFBs, mainly involving the severe cornea, lens, and retina injuries. The postoperative BCVA increased compared with the preoperative BCVA (z = −6.06, P < 0.01). The rate of recovery from blindness was 40.85% (29/71). The thin flat IOFB and long IOFB resulted in a better postoperative BCVA than the other two IOFB shapes (all P < 0.05). The irregular IOFB had a poorer silicone oil removal rate than the other three IOFB shapes (all P < 0.05). The IOFB extraction followed the limbus path in 18 cases, pars plana path in 27 cases, and entrance wound path in 28 cases. The IOFB length and width in the pars plana path group were significantly lower than that in the limbus path group (all P < 0.05), the preoperative BCVA of the pars plana path group was superior to that of the limbus path group (P < 0.05), and the IOFB length, width, and entrance wound length in the pars plana path group were significantly lower than in the entrance wound path group (all ...
    Schlagwörter intraocular foreign body ; giant ; secondary injury ; extraction ; surgery ; ocular trauma ; Medicine (General) ; R5-920
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag Frontiers Media S.A.
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  5. Artikel ; Online: The Widening Wealth Inequality as a Contributor to Increasing Household Carbon Emissions

    Xiaodi Qin / Haitao Wu / Xiaofang Zhang / Wei Wang

    Frontiers in Earth Science, Vol

    2022  Band 10

    Abstract: The Sustainable Development Goals call for taking urgent action to combat climate change and reduce inequalities. However, the related actions have not been effective. Global CO2 emissions in 2021 are projected to rebound to approaching the 2018–2019 ... ...

    Abstract The Sustainable Development Goals call for taking urgent action to combat climate change and reduce inequalities. However, the related actions have not been effective. Global CO2 emissions in 2021 are projected to rebound to approaching the 2018–2019 peak, and wealth inequality has been increasing at the very top of the distribution resulting from the COVID-19 pandemic. To test whether a trade-off exists between social and environmental benefits, this study calculates county-level wealth inequality with the Gini coefficient and consumption-based household carbon emissions with the emissions coefficient method and input–output modeling. Data are collected from the China Family Panel Studies, the Visible Infrared Imaging Radiometer Suite, the Chinese National Bureau of Statistics and Carbon Emission Account and Datasets in 2014, 2016 and 2018. In addition, a high-dimensional fixed-effects model, an instrumental variable model and causal mediation analysis are adopted to empirically test how wealth inequality influences household carbon emissions and explore the underlying mechanisms. The results show that county-level wealth inequality has a positive impact on household carbon emissions per capita. This means that policies designed to narrow the wealth gap can help reduce carbon emissions, making progress toward multiple SDGs. Moreover, the study reveals that the social norms of the Veblen effect and short-termism play an important role in mediating the relationship between wealth inequality and consumption-based household carbon emissions. This finding provides a new perspective to understand the mechanism behind wealth inequality and household carbon emissions related to climate change.
    Schlagwörter wealth inequality ; household carbon emissions ; climate change ; veblen effect ; short-termism ; Science ; Q
    Thema/Rubrik (Code) 338
    Sprache Englisch
    Erscheinungsdatum 2022-03-01T00:00:00Z
    Verlag Frontiers Media S.A.
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: How the mechanical microenvironment of stem cell growth affects their differentiation

    Xiaofang Zhang / Sibo Zhang / Tianlu Wang

    Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-

    a review

    2022  Band 17

    Abstract: Abstract Stem cell differentiation is of great interest in medical research; however, specifically and effectively regulating stem cell differentiation is still a challenge. In addition to chemical factors, physical signals are an important component of ... ...

    Abstract Abstract Stem cell differentiation is of great interest in medical research; however, specifically and effectively regulating stem cell differentiation is still a challenge. In addition to chemical factors, physical signals are an important component of the stem cell ecotone. The mechanical microenvironment of stem cells has a huge role in stem cell differentiation. Herein, we describe the knowledge accumulated to date on the mechanical environment in which stem cells exist, which consists of various factors, including the extracellular matrix and topology, substrate stiffness, shear stress, hydrostatic pressure, tension, and microgravity. We then detail the currently known signalling pathways that stem cells use to perceive the mechanical environment, including those involving nuclear factor-kB, the nicotinic acetylcholine receptor, the piezoelectric mechanosensitive ion channel, and hypoxia-inducible factor 1α. Using this information in clinical settings to treat diseases is the goal of this research, and we describe the progress that has been made. In this review, we examined the effects of mechanical factors in the stem cell growth microenvironment on stem cell differentiation, how mechanical signals are transmitted to and function within the cell, and the influence of mechanical factors on the use of stem cells in clinical applications.
    Schlagwörter Stem cell ; Extracellular matrix ; Shear stress ; Hydrostatic pressure ; Tension ; Microgravity ; Medicine (General) ; R5-920 ; Biochemistry ; QD415-436
    Thema/Rubrik (Code) 571
    Sprache Englisch
    Erscheinungsdatum 2022-08-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Artikel ; Online: Research on the Trade-Offs and Synergies of Ecosystem Services and Their Impact Factors in the Taohe River Basin

    Jing Zhou / Bo Zhang / Yaowen Zhang / Yuhan Su / Jie Chen / Xiaofang Zhang

    Sustainability, Vol 15, Iss 9689, p

    2023  Band 9689

    Abstract: The Taohe River Basin is an essential ecological function area in the upper reaches of the Yellow River. Understanding the intricate trade-offs and synergies between ecosystem services (ESs) and exploring the impact of different factors are essential for ...

    Abstract The Taohe River Basin is an essential ecological function area in the upper reaches of the Yellow River. Understanding the intricate trade-offs and synergies between ecosystem services (ESs) and exploring the impact of different factors are essential for achieving win–win outcomes in ecosystem management and socioeconomic development. The role of impact factors on the relationship between ESs, nevertheless, is more challenging to spatialize. This study used different models to estimate the net primary productivity (NPP), water yield (WY), and soil conservation (SC), and analyzed synergies and trade-offs between Ess. The spatial heterogeneity of the effects of natural and social factors on the relationships between Ess was explored using a geographic detector and a multi-scale geographically weighted regression (MGWR) model. The results show that: (1) NPP, WY, and SC all exhibit a rising trend, with multi-year averages of 488.99 gC/m 2 , 157.29 mm, and 1441.51 t/hm 2 , respectively; (2) NPP–WY and NPP–SC exhibit trade-offs in the majority of regions, while WY–SC are primarily synergistic in the upper and middle reaches, and they have the highest percentage of cropland, forest, and grassland; and (3) precipitation (PRE) has the greatest impact on the trade-off between NPP–WY and NPP–SC in the upper and middle reaches, and the gross domestic product (GDP), population density (POP), and distance from cropland (CROP) are the primary factors determining the synergy between NPP and WY in the lower reaches of the Loess Plateau cropping sector. PRE, digital elevation model (DEM), and CROP are the primary impact factors affecting the synergy of WY–SC. This study may serve as a reference for examining the evolutionary mechanism underlying the trade-offs and synergies between ESs and provide a scientific basis for future ecological environmental protection and regional land management in the Taohe River Basin.
    Schlagwörter ecosystem services ; trade-off and synergy ; impact factors ; multi-scale geographically weighted regression ; Taohe River Basin ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 333
    Sprache Englisch
    Erscheinungsdatum 2023-06-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Artikel ; Online: Predictors of acculturation attitude of international students in China.

    Man Luo / Xiaofang Zhang / Fang Peng / Jing Zhao / Haijun Deng

    PLoS ONE, Vol 16, Iss 11, p e

    2021  Band 0260616

    Abstract: This study investigates international students' acculturation attitude preference and the influence factors (i.e., gender, duration in China, host and English proficiency, adult attachment style and social ties) on each acculturation attitude (i.e, ... ...

    Abstract This study investigates international students' acculturation attitude preference and the influence factors (i.e., gender, duration in China, host and English proficiency, adult attachment style and social ties) on each acculturation attitude (i.e, integration, assimilation, separation and marginalization attitude) in China. A group of 229 international students within China responded online. Results from cluster analysis based on process model of acculturation revealed that, integration was the most prevalent acculturation attitude of international students in China. Additionally, logistic regressions analysis indicated that duration in China was negatively associated with adoption of separation and marginalization attitude also higher level of English proficiency predicted the preference of marginalization attitude. However, Chinese proficiency was positively associated with integration attitude adoption, host ties were positively and significantly associated with adoption of assimilation and integration attitude, but negatively associated with the usage of marginalization attitude. Lastly, avoidance attachment was found negatively associating with the integration attitude. This study provides valuable insights for international student education policymakers to assist international students in order to adapt to a new environment quickly and effectively.
    Schlagwörter Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 950
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Using Leaf Ecological Stoichiometry to Direct the Management of Ligularia virgaurea on the Northeast Qinghai-Tibetan Plateau

    Haohai Su / Jiabao Cui / Jan F. Adamowski / Xiaofang Zhang / Asim Biswas / Jianjun Cao

    Frontiers in Environmental Science, Vol

    2022  Band 9

    Abstract: Leaf ecological stoichiometry not only reflects the plasticity and adaptability, but also the growth of plants within environments where temperature, precipitation, and soil properties vary across an elevation gradient. Ligularia virgaurea (Maxim.) Mattf. ...

    Abstract Leaf ecological stoichiometry not only reflects the plasticity and adaptability, but also the growth of plants within environments where temperature, precipitation, and soil properties vary across an elevation gradient. Ligularia virgaurea (Maxim.) Mattf. ex Rehder & Kobuski — an invasive poisonous plant — is common in the northeast portion of China’s Qinghai-Tibetan Plateau and its presence greatly affects the native ecosystem. Based on L. virgaurea leaf carbon ([C]leaf), nitrogen ([N]leaf) and phosphorus ([P]leaf) concentrations, and their ratios, the species’ coping strategies across an elevation gradient (2,600 m, 3,000 m, and 3,300 m) were identified, and served to inform the development of improved management strategies. Mean [C]leaf, [N]leaf and [P]leaf in L. virgaurea across all elevations were 413.14 g·kg−1, 22.76 g·kg−1, and 1.34 g·kg−1, respectively, while [C]leaf: [N]leaf, [C]leaf: [P]leaf, and [N]leaf: [P]leaf were 18.27, 328.76, and 17.93. With an increase in precipitation and decrease in temperature from 2,600 m to 3,000 m–3,300 m, [C]leaf, [C]leaf: [N]leaf and [C]leaf: [P]leaf of L. virgaurea decreased at first and then increased. The [N]leaf and [P]leaf gradually increased, whereas [N]leaf: [P]leaf showed little change. Although temperature, precipitation and soil water content were the main factors affecting the ecological stoichiometry of L. virgaurea leaves, their roles in influencing leaf elements were different. The [C]leaf was mainly influenced by soil water content, [N]leaf by temperature and soil water content, and [P]leaf by all of them. With potential future climate change in the study area, L. virgaurea may grow faster than at present, although soil P may still be a growth-limiting element. As L. virgaurea can reduce plant diversity and the quality of forage, while increasing biomass, management of L. virgaurea should receive greater attention.
    Schlagwörter toxic weeds ; alpine region ; elevation ; plant element concentration ; warming ; Environmental sciences ; GE1-350
    Sprache Englisch
    Erscheinungsdatum 2022-02-01T00:00:00Z
    Verlag Frontiers Media S.A.
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: Characteristic of Stomatal Conductance and Optimal Stomatal Behaviour in an Arid Oasis of Northwestern China

    Tuo Han / Qi Feng / Tengfei Yu / Xiaomei Yang / Xiaofang Zhang / Kuan Li

    Sustainability, Vol 14, Iss 968, p

    2022  Band 968

    Abstract: Stomatal conductance ( g s ), the process that governs plant carbon uptake and water loss, is fundamental to most Land Surface Models (LSMs). With global change accelerating, more attention should be paid to investigating stomatal behavior, especially in ...

    Abstract Stomatal conductance ( g s ), the process that governs plant carbon uptake and water loss, is fundamental to most Land Surface Models (LSMs). With global change accelerating, more attention should be paid to investigating stomatal behavior, especially in extremely arid areas. In this study, gas exchange measurements and environmental/biological variables observations during growing seasons in 2016 and 2017 were combined to investigate diurnal and seasonal characteristics of g s and the applicability of the optimal stomatal conductance model in a desert oasis vineyard. The results showed that the responses of g s to environmental factors (photosynthesis active radiation, PAR

    vapor pressure deficit, VPD

    and temperature, T ) formed hysteresis loops in the daytime. The stomatal conductance slope, g 1 , a parameter in the unified stomatal optimal model, varied in different growing seasons and correlated with the soil-to-leaf hydraulic conductance (K L ). These results indicated the potential bias when using a constant g 1 value to simulate g s and highlighted that the water-use strategy of oasis plants might not be consistent throughout the entire growing season. Our findings further help to achieve a better understanding of stomata behavior in responding to climate change and encourage future efforts toward a more accurate parameterization of g s to improve the modeling of LSMs.
    Schlagwörter stomatal conductance ; hysteresis loops ; seasonal variation ; stomatal conductance slope ; soil-to-leaf hydraulic conductance ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 580
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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