LIVIVO - Search results -

Search results

Result 1 - 10 of total 19

Search options

Article ; Online: The effect of the leisure activities based on chess and cards for improving cognition of older adults

Xiaojuan Shi / Yanrong wang / Yueping Wu / Jiangping Li

Trials, Vol 24, Iss 1, Pp 1-

study protocol for a cluster randomized controlled trial

2023 Volume 10

Abstract: Abstract Background With the increase in age, the probability of cognitive impairment in the older people is increasing. More and more evidence shows that participating in leisure activities, especially chess and cards, is beneficial to the cognition and ...

Abstract	Abstract Background With the increase in age, the probability of cognitive impairment in the older people is increasing. More and more evidence shows that participating in leisure activities, especially chess and cards, is beneficial to the cognition and mental state of the older people. But the evidence for causal inference is limited. There is a need to conduct a fully powered randomized controlled trial (RCT) and long-term follow-up to test the effectiveness of intervention measures in improving cognitive function and mental state. This paper describes the methodology of a cluster RCT designed to determine the effect of chess and cards leisure activities on the cognitive function of the older people over 60 years old. Methods/design A cluster RCT consisting of 8 clusters will be conducted in four regions of Ningxia, China (Helan, Litong, Qingtongxia, and Shapotou). Clusters will be randomly assigned to the advocacy intervention group, which is also delivered with free leisure activities tools (chess and cards), or the control group. A baseline survey will be conducted before the intervention. A mid-term and final survey will be carried out twelve and twenty-four months after the intervention, respectively. The primary outcome is a change in cognitive function, and the secondary outcomes are changes in anxiety, depression, and loneliness. Discussion The results of this RCT will be helpful to (1) confirm the effectiveness of chess and cards leisure activities in improving the cognitive function of the older people over 60 years old; (2) determine the relationship between the frequency and duration of chess and cards leisure activities and cognitive function; (3) provide evidence of promoting participation in leisure activities through education campaigns and free provision of chess and cards tools; and (4) provide valuable information for successful aging. Trial registration Chinese Clinical Trial Registry: ChiCTR2200066817. Registered on 19 December 2022.
Keywords	Leisure activities ; Cognitive function ; Promotion campaigns ; Chess and cards ; Medicine (General) ; R5-920
Subject code	120
Language	English
Publishing date	2023-07-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Mangcuo Lake in Hengduan Mountains

Fang Wang / Yongbing Yang / Gang Song / Xiaojuan Shi / Bu Pu / Le Yang

Animals, Vol 13, Iss 1139, p

An Important Alpine Breeding and Stopover Site along Central Asian Flyway

2023 Volume 1139

Abstract: The stopovers provide food and habitat for migratory birds and therefore play an important role in facilitating the birds’ completion of their migration. The Hengduan Mountains, which have a complex topography, are located in a large corridor of the ... ...

Abstract	The stopovers provide food and habitat for migratory birds and therefore play an important role in facilitating the birds’ completion of their migration. The Hengduan Mountains, which have a complex topography, are located in a large corridor of the Central Asian migratory flyway, so the lakes along the Hengduan Mountains are important for waterbird migration. The existing research on lakes in the Hengduan Mountain area is mostly concentrated in the central and southern parts of the mountains, which proves that many lakes are wintering grounds for migrating birds. We wonder whether the ecological functions of lakes will change more with further elevation. With this question, we conducted four surveys for the seasonal bird survey in Mangcuo Lake, which is located in the northwest of the Hengduan Mountains, in Markam County of Qamdo City, between October 2019 and July 2020. We recorded a total of 6109 birds from 20 species of waterbirds, including 20 species of migratory waterbirds, accounting for 100% of all bird species. The diversity and richness of waterbirds in Mangtso Lake is shown as spring > autumn ≥, summer > winter, with no waterbirds in winter. The black-necked grebe ( Podiceps nigricollis ), great crested grebe ( Podiceps cristatus ), bar-headed goose ( Anser indicus ), and ruddy shelduck ( Tadorna ferruginea ) were the dominant species in the waterbird community. The highest number of waterbird species and total individuals were found in the transition zone between the marsh wetlands and lakes, and the number of waterbird species differed significantly among habitats (X 2 = 14.405, p = 0.000), with habitat complexity being an important factor influencing waterfowl abundance and distribution. The IUCN Red-listed species recorded include the black-necked crane ( Grus nigricollis ), painted stork ( Mycteria leucocephala ), and common pochard ( Aythya ferina ). By comparing with other lakes in Hengduan Mountain, we found that the ecological functions of the plateau lakes in the Hengduan Mountains, ...
Keywords	Hengduan Mountains ; Mangcuo Lake ; migration stopover site ; Central Asian flyway ; waterbirds ; Veterinary medicine ; SF600-1100 ; Zoology ; QL1-991
Subject code	590
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Happiness, depression, physical activity and cognition among the middle and old-aged population in China

Xiaojuan Shi / Xiaoxue He / Degong Pan / Hui Qiao / Jiangping Li

PeerJ, Vol 10, p e

a conditional process analysis

2022 Volume 13673

Abstract: Background Happiness is one variable of subjective well-being, which has been increasingly shown to have protective effects on health. Although the association between happiness and cognition has been established, the mechanism by which happiness leads ... ...

Abstract	Background Happiness is one variable of subjective well-being, which has been increasingly shown to have protective effects on health. Although the association between happiness and cognition has been established, the mechanism by which happiness leads to cognition remains unclear. Since happiness, depression, and physical activity may all be related to cognition, and happiness is related to depression and physical activity, this study explored the effect of depression and physical activity on the relationship between happiness and cognition among middle and old-aged individuals in China. Methods Data on 14,344 participants above 45 years of age were obtained from the 2018 China Family Panel Studies survey. A multiple linear regression analysis was performed to identify the correlation factors of cognition. The conditional process analysis was used to assess the mediatory effect of depression and physical activity on the relationship between happiness and cognition. Results Residence, age, sex, income level, social status, smoking, napping, reading, education, exercise times, satisfaction, happiness, and depression had associations with cognition. When other variables were held constant, cognition score increased by 0.029 standard deviation(SD) for every 1 SD increased in happiness. Mediation analysis showed that happiness had a significant positive total effect on cognition. The direct effect of happiness was significant and accounted for 57.86% of the total effect. The mediatory effect of depression (path of happiness→depression→cognition) accounted for 38.31% of the total effect, whereas that of physical activity (path of happiness→exercise times→cognition) accounted for 3.02% of the total effect. Conclusion Happiness has a positive correlation with cognitive function, and depression and physical activity play mediatory roles in this association. Effective interventions to improve happiness levels of middle and old-aged population will not only improve their subjective well-being but also improve their ...
Keywords	Happiness ; Cognition ; Depression ; Physical activity ; Medicine ; R
Subject code	120
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Late nitrogen fertilization improves cotton yield through optimizing dry matter accumulation and partitioning

Yu Tian / Fangyong Wang / Xiaojuan Shi / Feng Shi / Nannan Li / Junhong Li / Karine Chenu / Honghai Luo / Guozheng Yang

Annals of Agricultural Sciences, Vol 68, Iss 1, Pp 75-

2023 Volume 86

Abstract: Cotton (Gossypium hirsutum L.) production efficiency is constrained by issues such as a low nitrogen (N) utilization rate (30–35 %) and high N application rate (300–350 kg ha−1) in particular arid climates, such as Xinjiang, the largest irrigated cotton- ... ...

Abstract	Cotton (Gossypium hirsutum L.) production efficiency is constrained by issues such as a low nitrogen (N) utilization rate (30–35 %) and high N application rate (300–350 kg ha−1) in particular arid climates, such as Xinjiang, the largest irrigated cotton-producing region in China. These issues could be alleviated by allocating more N to late application to satisfy plant needs for growth and development. Over a three-year (2019–2021) field experiment, 240 kg ha−1 N was applied in 3 periods (squaring, flowering to peak boll, and late peak boll). The amount of N applied in the second period was fixed at 60 %, and the remaining 40 % was split between the first and the third periods, with five ratios (treatments), i.e., 0:6:4 (N064), 1:6:3 (N163), 2:6:2 (N262), 3:6:1 (N361) and 4:6:0 (N460), to investigate cotton response in terms of growth, biomass accumulation, and yield. Compared with the conventional treatment (N262), the N064 treatment narrowed the plant width by 11.7–12.0 %, increased canopy light transmittance by 6.1–56.9 %, extended the boll growth period by 8.8–9.4 %, improved defoliation by 9.3–11.7 % and increased both seed cotton yield and N partial factor productivity by 7.1–8.1 %, depending on the year. N064 accumulated 4.3–39.5 % more biomass (K) than N262, with the average and maximum growth rates of the reproductive organs (Vt and Vm, respectively) increasing by 8.6–89.0 % and 6.9–125.7 %, respectively, while the fast growth duration (∆t) shortened by 9.9–31.6 %. Again, N064 partitioned 1.5–35.8 % more biomass to bolls (higher partitioning index, PIboll). Seed cotton yield was significantly positively correlated with K, t1, Vt, Vm and PIboll and negatively correlated with ∆t in reproductive organs. Collectively, the data suggest that allocating more N to late application could be an efficient N fertilizer management strategy in arid areas under N-reduced cultivation and fertigation.
Keywords	Cotton ; Late nitrogen fertilization ; Biomass accumulation ; Yield ; Nitrogen partial factor productivity ; Agriculture (General) ; S1-972
Subject code	580
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Secular trend of non-communicable chronic disease prevalence throughout the life span who endured Chinese Great Famine (1959–1961)

Xiaoxue He / Xiaojuan Shi / Degong Pan / Huihui Wang / Xue Zhang / Lining Pu / Mingxiu Luo / Jiangping Li

BMC Public Health, Vol 23, Iss 1, Pp 1-

2023 Volume 9

Abstract: Abstract Background Famine is a risk factor for non-communicable chronic diseases (NCDs), which account for over 80% of deaths in China. The effect of famine on the prevalence of NCDs in terms of various age groups, time periods and cohorts is currently ... ...

Abstract	Abstract Background Famine is a risk factor for non-communicable chronic diseases (NCDs), which account for over 80% of deaths in China. The effect of famine on the prevalence of NCDs in terms of various age groups, time periods and cohorts is currently poorly understood. Objective This study aims to explore long-term trends in the impact of China’s Great Famine (1959–1961) on NCDs in China. Methods This study used data from the 2010–2020 China Family Panel Longitudinal Survey across 25 provinces in China. The subjects were aged 18–85 years, and the total number of subjects was 174,894. The prevalence of NCDs was derived from the China Family Panel Studies database (CFPS). An age-period-cohort (APC) model was used to estimate the age, period and cohort effects of NCDs in 2010–2020 and the effect of famine on the risk of NCDs in terms of cohort effects. Results The prevalence of NCDs increased with age. Additionally, the prevalence did not clearly decrease over the survey period. Regarding the cohort effect, people born in the years adjacent to the famine period had a higher risk of NCDs; additionally, females, those born in rural areas, and those who lived in provinces with severe famine and post-famine had a higher likelihood of NCDs. Conclusions Experiencing famine at an early age or the experience of famine in a close relative’s generation (births after the onset of famine) are associated with an increased risk of NCDs. Additionally, more severe famine is associated with a higher risk of NCDs.
Keywords	Famine ; Non-communicable chronic diseases ; Age-period-cohort models ; Prevalence ; China Family Panel Studies ; Public aspects of medicine ; RA1-1270
Subject code	950
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Fertilizer Reduction Combined with Organic Liquid Fertilizer Improved Canopy Structure and Function and Increased Cotton Yield

Qi Liang / Xiaojuan Shi / Nannan Li / Feng Shi / Yu Tian / Hongxia Zhang / Xianzhe Hao / Honghai Luo

Agronomy, Vol 12, Iss 8, p

2022 Volume 1759

Abstract: The application of organic liquid fertilizer combined with chemical fertilizer is one of the key technologies used to simultaneously improve cotton yield and efficiently utilize resources. However, organic fertilizer is usually applied once as a base ... ...

Abstract	The application of organic liquid fertilizer combined with chemical fertilizer is one of the key technologies used to simultaneously improve cotton yield and efficiently utilize resources. However, organic fertilizer is usually applied once as a base fertilizer during production, and few studies have been conducted on topdressing with water during the growth period. Therefore, in this study, Xinluzao 74 was used as the experimental material, and a single fertilizer application (CF) was used as a control in 2019–2020 under the conditions of integrated control of water and fertilizer with mulch drip irrigation. Five combinations of reduction in chemical fertilizer combined with organic fertilizer (OF1, OF2, OF3, OF4, and OF5) were used to investigate the influences of chemical fertilizer combined with organic liquid fertilizer on the leaf area index (LAI), canopy openness (DIFN), mean foliage tilt angle (MTA), photosynthetically active radiation (PAR), canopy apparent photosynthesis (CAP), and yield and quality of cotton. The results show that among the different fertilization treatments, the OF2 treatment had the best results, not only ensuring a suitable LAI (4.8) and maintaining a large DIFN (0.1) but also increasing the light transmittance of the middle and lower canopies (0.02–0.03). At the same time, CAP increased significantly compared with that in the CF treatment, with an average increase of 12.8%. The high value lasted for a long time, and the late decay stage remained at 8.9 μmol m −2 s −1 . The ratio of the population respiration rate to total photosynthesis (CR/TCAP) decreased significantly, with an average decrease of 13.5%. Compared with that in CF, the lint yield increased by 27.0% in the other treatments. The correlation analysis showed that lint yield was positively correlated with the relative chlorophyll content (SPAD value), PAR transmittance (PARU) and CAP in the upper canopy ( p < 0.05) and significantly negatively correlated with PAR transmittance (PARM) in the middle canopy and PAR ...
Keywords	cotton ; canopy structure ; canopy apparent photosynthetic ; organic liquid fertilizer ; yield ; Agriculture ; S
Subject code	630
Language	English
Publishing date	2022-07-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Augmenting the Effectiveness of CAR-T Cells by Enhanced Self-Delivery of PD-1-Neutralizing scFv

Yu Ping / Feng Li / Shufeng Nan / Daiqun Zhang / Xiaojuan Shi / Jiqi Shan / Yi Zhang

Frontiers in Cell and Developmental Biology, Vol

2020 Volume 8

Abstract: Chimeric antigen receptor T (CAR-T) cell therapy is not satisfying in solid tumors. PD-1-mediated suppression greatly hinders CAR-T cells in the microenvironment. It has been shown that PD-1 blockade improves the effectiveness of CAR-T cells. Herein, we ... ...

Abstract	Chimeric antigen receptor T (CAR-T) cell therapy is not satisfying in solid tumors. PD-1-mediated suppression greatly hinders CAR-T cells in the microenvironment. It has been shown that PD-1 blockade improves the effectiveness of CAR-T cells. Herein, we designed CAR-T cells than could secret α-PD-1 scFv by themselves. To obtain optimal secretions of scFv, we screened several signal peptides. And the segment from human increased the extracellular production of PD-1-neutralizing proteins. The secreted neutralizing scFv efficiently blocked PD-1 and enhanced T cell activation when PD-L1 was present. Further analysis showed that CAR-T cells themselves could secret α-PD-1 scFv with bioactivity. In contrast to the prototype, the scFv-producing CAR-T cells demonstrated decreased PD-1 but increases expansion and toxicity against solid tumor cells. In the subcutaneous and orthotopic xenograft models, the self-delivered α-PD-1 scFv increased CAR-T cell functionalities and tumor-suppressions. Our work suggested that engineering T cells to co-express antigen-responsive receptors and checkpoint inhibitors is effective to optimize CAR-T cell therapy for solid tumors.
Keywords	chimeric antigen receptor T cell ; anti-PD-1 ; single-chain variable fragment ; tumor microenvironment ; T cell function ; Biology (General) ; QH301-705.5
Subject code	572
Language	English
Publishing date	2020-08-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: PD-1 abrogates the prolonged persistence of CD8+ CAR-T cells with 4-1BB co-stimulation

Feng Li / Zhen Zhang / Yujing Xuan / Daiqun Zhang / Jinyan Liu / Aitian Li / Shumin Wang / Ting Li / Xiaojuan Shi / Yi Zhang

Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-

2020 Volume 4

Keywords	Medicine ; R ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2020-08-01T00:00:00Z
Publisher	Nature Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: A Grey Interval Relational Degree-Based Dynamic Multiattribute Decision Making Method and Its Application in Investment Decision Making

Yuhong Wang / Xiaojuan Shi / Jihong Sun / Wuyong Qian

Mathematical Problems in Engineering, Vol

2014 Volume 2014

Keywords	Mathematics ; QA1-939 ; Science ; Q ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Technology ; T
Language	English
Publishing date	2014-01-01T00:00:00Z
Publisher	Hindawi Publishing Corporation
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: A Grey Interval Relational Degree-Based Dynamic Multiattribute Decision Making Method and Its Application in Investment Decision Making

Yuhong Wang / Xiaojuan Shi / Jihong Sun / Wuyong Qian

Mathematical Problems in Engineering, Vol

2014 Volume 2014

Keywords	Mathematics ; QA1-939 ; Science ; Q ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Technology ; T
Language	English
Publishing date	2014-01-01T00:00:00Z
Publisher	Hindawi Publishing Corporation
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED