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Article ; Online: Three-Dimensional Numerical Modeling of Artificially Freezing Ground in Metro Station Construction

Bo Wang / Jun Hu / Xiaoqi Lin / Hui Zeng

Applied Sciences, Vol 13, Iss 1, p

2023 Volume 671

Abstract: In this study, the engineering background of No. 2 complex connecting passage of Binhu Road Station/Jinhu Square Station of Nanning Metro Line 3 is investigated, where the artificial ground freezing technique is adopted. A three-dimensional finite ... ...

Abstract	In this study, the engineering background of No. 2 complex connecting passage of Binhu Road Station/Jinhu Square Station of Nanning Metro Line 3 is investigated, where the artificial ground freezing technique is adopted. A three-dimensional finite element model is established to investigate the temperature development of the frozen soil curtain, with a simulation of the dynamic evolution of the frosted soil curtain. The finite element model is validated by comparing the overall trend of the measured temperature value and the resulting temperature value, which are roughly the same. According to the design scheme, the weakest part of the whole frozen soil curtain is the top of the bell mouth where the downhole tunnel intersects the connecting passage. It is recommended to make a row of smaller freezing holes to enhance the freezing effect in this area. The thickness of the frozen soil curtain reached 1.75 m or more, indicating that the whole frozen soil curtain meets the design requirements and shows the right features for excavation construction. After freezing for 40 days, the average thickness of the frozen soil curtain is 2.4 m, indicating that the freezing effect meets the design requirements. The project can be successfully carried out, which suggests that the underneath passage construction is feasible. As a result, the results of the numerical model are applicable for comparable projects using artificially freezing ground in metro station construction.
Keywords	metro station construction ; water leakage ; artificially freezing ground ; heat transfer ; numerical simulation ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	690
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Elevated estradiol levels on hCG trigger day adversely effects on the clinical pregnancy rates of blastocyst embryo transfer but not cleavage-stage embryo transfer in fresh cycles

Yue Meng / Linlin Tao / Tingting Xia / Jieru Zhu / Xiaoqi Lin / Wen Zhou / Yuxia Liu / Jianping Ou / Weijie Xing

PeerJ, Vol 11, p e

a retrospective cohort study

2023 Volume 15709

Abstract: Background Elevated estradiol (E2) levels are an inevitable outcome of the controlled ovulation hyperstimulation. However, the effect of this change on pregnancy is still uncertain. Our study aimed to analyze the impact of increased serum E2 at the day ... ...

Abstract	Background Elevated estradiol (E2) levels are an inevitable outcome of the controlled ovulation hyperstimulation. However, the effect of this change on pregnancy is still uncertain. Our study aimed to analyze the impact of increased serum E2 at the day of human chorionic gonadotropin (hCG) administration on the clinical outcomes of women with fresh embryo transfer (ET) cycles. Methods This study included 3,009 fresh ET cycles from October 2015 to September 2021. Based on the stage of embryos transferred, these cycles were categorized into the cleavage group and blastocyst group. Both groups were then divided into four sets according to E2 levels when hCG was administered: set 1 (E2 ≤ 2,000 pg/ml), set 2 (E2 = 2,001–3,000 pg/ml), set 3 (E2 = 3,001–4,000 pg/ml), and set 4 (E2 > 4,000 pg/ml). The primary outcome was the clinical pregnancy rate (CPR). Binary logistics regression analysis was established to explore the association between CPR and E2 levels. Specifically, the threshold effect of serum E2 on CPR was revealed using the two-piecewise linear regression analyses. Results The multivariate regression model in the cleavage group showed that patients’ CPR in set 4 was 1.59 times higher than those in reference set 1, but the statistical difference was insignificant (P = 0.294). As for the blastocyst group, patients in set 4 had a lower CPR with adjusted ORs of 0.43 (P = 0.039) compared to patients in set 1. The inflection point for the blastocyst group was 39.7 pg/dl according to the results of the two-piecewise linear regression model. When E2 levels were over the point, the CPR decreased by 17% with every 1 pg/dl increases in serum E2 (adjusted OR = 0.83, 95% CI [0.72–0.96], P = 0.012). Conclusions Elevated E2 levels (>39.7 pg/dl) on hCG trigger day were associated with decreased CPR in patients with fresh blastocyst ET. However, it had no similar effect on the CPR of patients with fresh cleavage-stage ET.
Keywords	Fresh embryo transfer ; Clinical pregnancy ; High estradiol ; Embryo stage ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	610
Language	English
Publishing date	2023-07-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Using Enhanced Gap-Filling and Whittaker Smoothing to Reconstruct High Spatiotemporal Resolution NDVI Time Series Based on Landsat 8, Sentinel-2, and MODIS Imagery

Jieyu Liang / Chao Ren / Yi Li / Weiting Yue / Zhenkui Wei / Xiaohui Song / Xudong Zhang / Anchao Yin / Xiaoqi Lin

ISPRS International Journal of Geo-Information, Vol 12, Iss 214, p

2023 Volume 214

Abstract: Normalized difference vegetation index (NDVI) time series data, derived from optical images, play a crucial role for crop mapping and growth monitoring. Nevertheless, optical images frequently exhibit spatial and temporal discontinuities due to cloudy ... ...

Abstract	Normalized difference vegetation index (NDVI) time series data, derived from optical images, play a crucial role for crop mapping and growth monitoring. Nevertheless, optical images frequently exhibit spatial and temporal discontinuities due to cloudy and rainy weather conditions. Existing algorithms for reconstructing NDVI time series using multi-source remote sensing data still face several challenges. In this study, we proposed a novel method, an enhanced gap-filling and Whittaker smoothing (EGF-WS), to reconstruct NDVI time series (EGF-NDVI) using Google Earth Engine. In EGF-WS, NDVI calculated from MODIS, Landsat-8, and Sentinel-2 satellites were combined to generate high-resolution and continuous NDVI time series data. The MODIS NDVI was employed as reference data to fill missing pixels in the Sentinel–Landsat NDVI (SL-NDVI) using the gap-filling method. Subsequently, the filled NDVI was smoothed using a Whittaker smoothing filter to reduce residual noise in the SL-NDVI time series. With reference to the all-round performance assessment (APA) metrics, the performance of EGF-WS was compared with the conventional gap-filling and Savitzky–Golay filter approach (GF-SG) in Fusui County of Guangxi Zhuang Autonomous Region. The experimental results have demonstrated that the EGF-WS can capture more accurate spatial details compared with GF-SG. Moreover, EGF-NDVI of Fusui County exhibited a low root mean square error (RMSE) and a high coefficient of determination (R 2 ). In conclusion, EGF-WS holds significant promise in providing NDVI time series images with a spatial resolution of 10 m and a temporal resolution of 8 days, thereby benefiting crop mapping, land use change monitoring, and various ecosystems, among other applications.
Keywords	spatiotemporal fusion ; NDVI time series ; enhanced gap-filling ; Whittaker smoothing ; Google Earth Engine ; Geography (General) ; G1-922
Subject code	333
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: CD317+ MSCs expanded with chemically defined media have enhanced immunological anti-inflammatory activities

Jun Song / Qi Ma / Yumeng Li / Xianqi Wang / Si Chen / Bowei Liang / Xiaoqi Lin / Jieting Chen / Shiru Xu / Shaoquan Shi / Jingting Zhang / Lianghui Diao / Yong Zeng / Jianyong Xu

Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-

2024 Volume 12

Abstract: Abstract Background Although both preclinical and clinical studies have shown the great application potential of MSCs (mesenchymal stem/stromal cells) in treating many kinds of diseases, therapeutic inconsistency resulting from cell heterogeneity is the ... ...

Abstract	Abstract Background Although both preclinical and clinical studies have shown the great application potential of MSCs (mesenchymal stem/stromal cells) in treating many kinds of diseases, therapeutic inconsistency resulting from cell heterogeneity is the major stumbling block to their clinical applications. Cell population diversity and batch variation in the cell expansion medium are two major inducers of MSC heterogeneity. Methods Cell population diversity was investigated through single-cell RNA sequencing analysis of human MSCs derived from the umbilical cord and expanded with fully chemically defined medium in the current study. Then, the MSC subpopulation with enhanced anti-inflammatory effects was studied in vitro and in vivo. Results Our data showed that MSCs contain different populations with different functions, including subpopulations with enhanced functions of exosome secretion, extracellular matrix modification and responses to stimuli (regeneration and immune response). Among them, CD317+ MSCs have improved differentiation capabilities and enhanced immune suppression activities. Underlying mechanism studies showed that higher levels of TSG6 confer enhanced anti-inflammatory functions of CD317+ MSCs. Conclusions Thus, CD317+ MSCs might be a promising candidate for treating immunological disorder-related diseases.
Keywords	Mesenchymal stem/stromal cells ; MSCs ; TSG6 ; CD317 ; Immunosuppression ; Medicine (General) ; R5-920 ; Biochemistry ; QD415-436
Subject code	610
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Modification of Rigid Polyurethane Foams with the Addition of Nano-SiO 2 or Lignocellulosic Biomass

Qinqin Zhang / Xiaoqi Lin / Weisheng Chen / Heng Zhang / Dezhi Han

Polymers, Vol 12, Iss 1, p

2020 Volume 107

Abstract: Many achievements have been made on the research of composite polyurethane foams to improve their structure and mechanical properties, and the composite foams have been widely utilized in building insulation and furniture. In this work, rigid ... ...

Abstract	Many achievements have been made on the research of composite polyurethane foams to improve their structure and mechanical properties, and the composite foams have been widely utilized in building insulation and furniture. In this work, rigid polyurethane foams (RPUFs) with the addition of different fillers (nano-SiO 2 , peanut shell, pine bark) were prepared through the one-step method. The effects of inorganic nano-SiO 2 and organic biomass on foam properties were evaluated by means of physical and chemical characterization. The characterization results indicate that the compressive strength values of prepared foams could fully meet the specification requirement for the building insulation materials. The inorganic and organic fillers have no effect on the hydrogen bonding states in composite RPUFs. Furthermore, compared to the biomass fillers, the addition of nano-SiO 2 greatly influenced the final residual content of the fabricated foam. All composite foams exhibit closed-cell structure with smaller cell size in comparison with the parent foam. The prepared composite foams have the potential for utilization in building insulation.
Keywords	rigid polyurethane foam ; peanut shell ; pine bark ; nano-sio 2 ; insulation materials ; Organic chemistry ; QD241-441
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Degradation and Repolymerization Analysis on Solvolysis Liquefaction of Corn Stalk

Weisheng Chen / Qinqin Zhang / Xiaoqi Lin / Kaisen Jiang / Dezhi Han

Polymers, Vol 12, Iss 2337, p

2020 Volume 2337

Abstract: One of the most effective and renewable utilization methods for lignocellulosic feedstocks is the transformation from solid materials to liquid products. In this work, corn stalk (CS) was liquified with polyethylene glycol 400 (PEG400) and glycerol as ... ...

Abstract	: One of the most effective and renewable utilization methods for lignocellulosic feedstocks is the transformation from solid materials to liquid products. In this work, corn stalk (CS) was liquified with polyethylene glycol 400 (PEG400) and glycerol as the liquefaction solvents, and sulfuric acid as the catalyst. The liquefaction conditions were optimized with the liquefaction yield of 95.39% at the reaction conditions of 150 °C and 120 min. The properties of CS and liquefaction residues (LRs) were characterized using ATR–FTIR, TG, elemental analysis and SEM. The chemical components of liquefied product (LP) were also characterized by GC–MS. The results indicated that the depolymerization and repolymerization reaction took place simultaneously in the liquefaction process. The depolymerization of CS mainly occurred at the temperature of <150 °C, and the repolymerization of biomass derivatives dominated at a higher temperature of 170 °C by the lignin derivatives repolymerization with cellulose derivatives, hemicellulose derivatives and PEG400 and self-condensation of lignin derivatives. The solvolysis liquefaction of CS could be classified into the mechanism of electrophilic substitution reaction attacked by the hydrogen cation.
Keywords	lignocellulosic biomass ; liquefaction ; corn stalk ; residue ; repolymerization ; utilization ; Organic chemistry ; QD241-441
Subject code	540
Language	English
Publishing date	2020-10-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Liquefaction of Peanut Shells with Cation Exchange Resin and Sulfuric Acid as Dual Catalyst for the Subsequent Synthesis of Rigid Polyurethane Foam

Qinqin Zhang / Weisheng Chen / Guojuan Qu / Xiaoqi Lin / Dezhi Han / Xiaofei Yan / Heng Zhang

Polymers, Vol 11, Iss 6, p

2019 Volume 993

Abstract: The conversion of lignocellulosic biomass from renewable raw materials to high value-added fine chemicals expanded their application in biodegradable polymers materials synthesis, such as polyurethanes and phenolic resin, etc. In this work, the strong- ... ...

Abstract	The conversion of lignocellulosic biomass from renewable raw materials to high value-added fine chemicals expanded their application in biodegradable polymers materials synthesis, such as polyurethanes and phenolic resin, etc. In this work, the strong-acid cation exchange resin and sulfuric acid as the dual catalyst offered an effective way to catalyze the liquefaction reaction of the peanut shells. The properties of liquefied products were characterized by means of hydroxyl value, viscosity and solubility tests, while the properties of peanut shells and liquefaction residue were analyzed by means of ATR-FTIR, TG and SEM techniques. The results indicated that the liquefied products could be completely dissolved in deionized water, methanol and polyethylene glycol, respectively, and they could be a preferable substitution of petrochemical polyols as soft segments to synthesize the rigid polyurethane foams. Moreover, the cellulose and hemicellulose in the peanut shells were easily decomposed into smaller molecules via the breakage of the C−O bond besides five-membered and hexatomic ring, while the lignin could be degraded via the breakage of the C−O chemical bonds of β-O-4, 4-O-5 and dibenzodioxocin units. The fabricated rigid polyurethane (RPU) foam, containing higher percentage of open pores with uniform size, can be potentially utilized for flower mud and sound-absorbing materials.
Keywords	lignocellulosic biomass ; peanut shells ; liquefaction reaction ; strong-acid cation exchange resin ; polyols ; rigid polyurethane foam ; Organic chemistry ; QD241-441
Subject code	540
Language	English
Publishing date	2019-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Open-Cell Rigid Polyurethane Foams from Peanut Shell-Derived Polyols Prepared under Different Post-Processing Conditions

Guangyu Zhang / Yumin Wu / Weisheng Chen / Dezhi Han / Xiaoqi Lin / Gongchen Xu / Qinqin Zhang

Polymers, Vol 11, Iss 9, p

2019 Volume 1392

Abstract: Bio-based polyurethane materials with abundant open-cells have wide applications because of their biodegradability for addressing the issue of environmental conservation. In this work, open-cell rigid polyurethane foams (RPUFs) were prepared with bio- ... ...

Abstract	Bio-based polyurethane materials with abundant open-cells have wide applications because of their biodegradability for addressing the issue of environmental conservation. In this work, open-cell rigid polyurethane foams (RPUFs) were prepared with bio-based polyols (BBPs) derived from the liquefaction of peanut shells under different post-processing conditions. The influences of the neutralization procedure and filtering operation for BBPs on the foaming behaviors, density, dimensional stability, water absorption, swelling ratio, compressive strength, and microstructure of RPUFs were investigated intensively. The results revealed that a small amount of sulfuric acid in the polyols exhibited a great impact on physical and chemical properties of RPUFs while the filtering operation for those polyols had a slight effect on the above properties. The RPUFs prepared from neutralized BBPs possessed higher water absorption, preferable dimensional stability and compression strength than that fabricated from the non-neutralized BBPs. Moreover, the prepared RPUFs exhibited preferable water absorption of 636−777%, dimensional stability of <0.5%, compressive strength of >200 KPa, lower swelling rate of ca. 1%, as well as uniform cell structure with superior open-cell rate, implying potential applications in floral foam.
Keywords	rigid polyurethane foams ; bio-based polyols ; peanut shell ; floral foam ; Organic chemistry ; QD241-441
Subject code	620
Language	English
Publishing date	2019-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer

Sia Viborg Lindskrog / Frederik Prip / Philippe Lamy / Ann Taber / Clarice S. Groeneveld / Karin Birkenkamp-Demtröder / Jørgen Bjerggaard Jensen / Trine Strandgaard / Iver Nordentoft / Emil Christensen / Mateo Sokac / Nicolai J. Birkbak / Lasse Maretty / Gregers G. Hermann / Astrid C. Petersen / Veronika Weyerer / Marc-Oliver Grimm / Marcus Horstmann / Gottfrid Sjödahl /

Mattias Höglund / Torben Steiniche / Karin Mogensen / Aurélien de Reyniès / Roman Nawroth / Brian Jordan / Xiaoqi Lin / Dejan Dragicevic / Douglas G. Ward / Anshita Goel / Carolyn D. Hurst / Jay D. Raman / Joshua I. Warrick / Ulrika Segersten / Danijel Sikic / Kim E. M. van Kessel / Tobias Maurer / Joshua J. Meeks / David J. DeGraff / Richard T. Bryan / Margaret A. Knowles / Tatjana Simic / Arndt Hartmann / Ellen C. Zwarthoff / Per-Uno Malmström / Núria Malats / Francisco X. Real / Lars Dyrskjøt

Nature Communications, Vol 12, Iss 1, Pp 1-

2021 Volume 18

Abstract: Multiple molecular profiling methods are required to study urothelial non-muscle-invasive bladder cancer (NMIBC) due to its heterogeneity. Here the authors integrate multi-omics data of 834 NMIBC patients, identifying a molecular subgroup associated with ...

Abstract	Multiple molecular profiling methods are required to study urothelial non-muscle-invasive bladder cancer (NMIBC) due to its heterogeneity. Here the authors integrate multi-omics data of 834 NMIBC patients, identifying a molecular subgroup associated with multiple alterations and worse outcomes.
Keywords	Science ; Q
Language	English
Publishing date	2021-04-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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