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Article ; Online: Evaluation of the Development Capability of the New Energy Vehicle Industry

Fansheng Meng / Xiaoye Jin

Sustainability, Vol 11, Iss 9, p

An Empirical Study from China

2019 Volume 2635

Abstract: In order to alleviate the pressures of environmental pollution and the energy crisis, and to lay out and capture huge emerging markets as soon as possible, all countries in the world are vigorously developing new energy vehicles (NEVs). This paper ... ...

Abstract	In order to alleviate the pressures of environmental pollution and the energy crisis, and to lay out and capture huge emerging markets as soon as possible, all countries in the world are vigorously developing new energy vehicles (NEVs). This paper analyzes the factors influencing the development capability of the NEV industry from the aspects of autonomy, controllability, and stability, and constructs an evaluation index system. Based on the improved entropy method and the catastrophe progression method, we establish an evaluation model for the development capability of China’s NEV industry and comprehensively evaluate the development capability of 15 new energy auto companies. An empirical analysis finds that the outlook for the overall development capability of China’s NEV industry is not optimistic, and there is a big gap in the industry, lacking core technology and independent innovation capability. We propose countermeasures such as increasing research and development (R&D) investment and innovation, and improving policy support.
Keywords	new energy vehicles ; development ability ; influencing factor ; improved entropy method ; catastrophe progression method ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	650
Language	English
Publishing date	2019-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Insight into forensic efficiency and genetic structure of the Guizhou Dong group via a 64-plex panel

Wen Wan / Zheng Ren / Hongling Zhang / Qiyan Wang / Ting Wang / Yunteng Yang / Jiangtao You / Kun He / Jiang Huang / Xiaoye Jin

Frontiers in Ecology and Evolution, Vol

2023 Volume 10

Abstract: Insertion/deletion polymorphisms (InDels) show great application values in forensic research because they own superiorities of short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs). Whereas, InDels commonly display low genetic ... ...

Abstract	Insertion/deletion polymorphisms (InDels) show great application values in forensic research because they own superiorities of short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs). Whereas, InDels commonly display low genetic diversities in comparison to STRs. Therefore, they may provide limited genetic information in forensic kinship testing. Here, we evaluated forensic application efficiency of a novel multiplex amplification system including two STRs, 59 InDels, and three sex-determination loci in the Guizhou Dong group. In addition, we explored the genetic background of the Guizhou Dong group in comparison to other reported populations based on 59 InDels. We found that 59 InDels displayed relatively high genetic diversities in the Guizhou Dong group. Moreover, the cumulative forensic efficiency of two STRs and 59 InDels could meet the requirement of individual identification and paternity testing in the Guizhou Dong group. For these 59 InDels, we observed that some loci exhibited relatively high genetic differentiations among different continental populations, especially for African and Non-African populations, which could be viewed as candidate ancestry informative markers in the future. Genetic structure results indicated that the Dong group had close genetic relationships with East Asian and some Southern Chinese Han populations. To sum up, we stated that the 64-plex panel could be performed for forensic application of the Guizhou Dong group.
Keywords	InDels ; Dong ; STR ; forensic application ; population genetic background ; Evolution ; QH359-425 ; Ecology ; QH540-549.5
Subject code	590
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Factors Influencing the Development Ability of Intelligent Manufacturing of New Energy Vehicles Based on a Structural Equation Model

Xiaoye Jin / Meiying Li / Wanyu Zhang / Jingwen Cui / Fansheng Meng

ACS Omega, Vol 5, Iss 29, Pp 18262-

2020 Volume 18272

Keywords	Chemistry ; QD1-999
Language	English
Publishing date	2020-07-01T00:00:00Z
Publisher	American Chemical Society
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genetic Structural Differentiation Analyses of Intercontinental Populations and Ancestry Inference of the Chinese Hui Group Based on a Novel Developed Autosomal AIM-InDel Genotyping System

Tong Xie / Chunmei Shen / Xiaoye Jin / Qiong Lan / Yating Fang / Bofeng Zhu

BioMed Research International, Vol

2020 Volume 2020

Abstract: In the present study, we investigated the genetic polymorphisms of 39 ancestry informative marker-insertion/deletion (AIM-InDel) loci in the Chinese Hui group using a previously self-developed panel, further clarified the genetic relationships between ... ...

Abstract	In the present study, we investigated the genetic polymorphisms of 39 ancestry informative marker-insertion/deletion (AIM-InDel) loci in the Chinese Hui group using a previously self-developed panel, further clarified the genetic relationships between the Hui group and other reference populations, and assessed the ancestry inference efficiency of the AIM-InDel panel based on the worldwide population data from 1000 Genomes Phase 3. The results of the locus-specific informativeness (In) and pairwise fixation index (Fst) values, multidimensional scaling analysis, and success ratio of estimation with cross-validation showed that the novel panel could well reveal the genetic structural differentiations of the East Asian, European, African, and South Asian populations. Besides, the biogeographical ancestry origin inference both at the individual and population levels was conducted on the Chinese Hui group by principal component analysis and STRUCTURE analysis, and the results revealed that the Hui group had the East Asian origin, and the East Asian component ratio of Hui group was approximately 88.87%. Furthermore, the population genetic analyses among the Hui group and reference populations were performed based on the insertion allele frequency heat map, population pairwise Fst values and phylogenetic tree, and the results indicated that the Hui group was genetically closer to East Asian populations, especially two Chinese Han populations (CHS and CHB populations).
Keywords	Medicine ; R
Subject code	590
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Gene mapping and functional annotation of GWAS of oral ulcers using FUMA software

Xiaoye Jin / Yijie Wang / Xingru Zhang / Wenqing Zhang / Hongdan Wang / Chuanliang Chen

Scientific Reports, Vol 10, Iss 1, Pp 1-

2020 Volume 9

Abstract: Abstract Oral ulcers not only influence the physical health of patients, but they also interfere with their quality of life. However, the exact etiology of oral ulcers is not clear. To explore the roles of genetic factors in oral ulcers, a genome-wide ... ...

Abstract	Abstract Oral ulcers not only influence the physical health of patients, but they also interfere with their quality of life. However, the exact etiology of oral ulcers is not clear. To explore the roles of genetic factors in oral ulcers, a genome-wide association study of the condition in European individuals was re-evaluated by the FUMA v1.3.5e online tool. A total of 380 independent significant single nucleotide polymorphisms (SNPs) and 89 lead SNPs were identified in 34 genomic risk loci. Out of these identified genomic risk loci, 280 possible causal genes were pinpointed by positional mapping and expression quantitative trait locus mapping. Among these genes, 216 novel genes were identified. Furthermore, some genomic loci were mapped to a single gene. Functional annotation of these prioritized genes revealed that the immune response pathway was implicated in the onset of oral ulcers. Overall, our findings revealed novel possible causal genes and demonstrated that the immune response has a crucial role in the occurrence of oral ulcers.
Keywords	Medicine ; R ; Science ; Q
Subject code	610
Language	English
Publishing date	2020-07-01T00:00:00Z
Publisher	Nature Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Forensic efficiency evaluation of a novel multiplex panel of InDels and STRs in the Guizhou Han population and its phylogenetic relationships with other reference populations

Yanhua Zheng / Ting Wang / Kun He / Yunteng Yang / Jiangtao You / Xiaolan Huang / Hongling Zhang / Zheng Ren / Qiyan Wang / Jiang Huang / Xiaoye Jin

Annals of Human Biology, Vol 50, Iss 1, Pp 42-

2023 Volume 47

Abstract: Background Insertion/deletion polymorphism (InDel), as the third genetic marker, has been given a lot of attention by forensic geneticists since it has the advantages of extensive distributions in the human genome, small amplicon, and low mutation rate. ... ...

Abstract	Background Insertion/deletion polymorphism (InDel), as the third genetic marker, has been given a lot of attention by forensic geneticists since it has the advantages of extensive distributions in the human genome, small amplicon, and low mutation rate. However, the extant InDel panels were only viewed as supplemental tools for kinship analyses. In addition, these panels were not conductive to mixture deconvolution because InDels in these panels mainly displayed two alleles. Aims The purpose of this study is to investigate genetic distributions of a novel panel of InDels and STRs in the Guizhou Han population; assess the forensic application value of the panel; and conduct population genetic analyses of the Guizhou Han and other reference populations based on the overlapping loci. Subjects and methods The bloodstain samples of 209 Guizhou Han were gathered and genotyped by the novel panel. Allelic frequencies and forensic parameters of two miniSTRs and 59 InDels in the panel were estimated. In addition, we assessed phylogenetic relationships among the Guizhou Han and other reference populations by principal component analysis, DA genetic distance, and neighbor-joining tree. Results A total of 139 alleles of 61 loci could be observed in the Guizhou Han population. Polymorphic information content values of 59 InDels were greater than 0.3 in the Guizhou Han population. The cumulative power of discrimination and probability of exclusion of two miniSTRs and 59 InDels in the Guizhou Han population were 0.999999999999999999999999997984 and 0.9999986, respectively. Principal component analysis of 14 populations showed that the Guizhou Han population located closer to Hunan Han and Southern Han Chinese (CHS) populations. Similar results were also discerned from DA genetic distances and the neighbor-joining tree. Conclusion To sum up, the novel panel could be employed for forensic personal identification and paternity testing in the Guizhou Han population as a promising independent tool. Besides, the principal component ...
Keywords	indel ; str ; guizhou han ; principal component analysis ; population genetic analysis ; Biology (General) ; QH301-705.5 ; Human anatomy ; QM1-695 ; Physiology ; QP1-981
Subject code	590
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Taylor & Francis Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Comprehensive analyses of genetic diversities and population structure of the Guizhou Dong group based on 44 Y-markers

Hongling Zhang / Xiaolan Huang / Xiaoye Jin / Zheng Ren / Qiyan Wang / Meiqing Yang / Ronglan Xu / Xiang Yuan / Daiquan Yang / Hongyan Liu / Wanyi Shen / Huiying Zhang / Yangjie Que / Jiang Huang

PeerJ, Vol 11, p e

2023 Volume 16183

Abstract: Background The non-recombining region of the human Y chromosome (NRY) is a strictly paternally inherited genetic marker and the best material to trace the paternal lineages of populations. Y chromosomal short tandem repeat (Y-STR) is characterized by ... ...

Abstract	Background The non-recombining region of the human Y chromosome (NRY) is a strictly paternally inherited genetic marker and the best material to trace the paternal lineages of populations. Y chromosomal short tandem repeat (Y-STR) is characterized by high polymorphism and paternal inheritance pattern, so it has been widely used in forensic medicine and population genetic research. This study aims to understand the genetic distribution of Y-STRs in the Guizhou Dong population, provide reference data for forensic application, and explore the phylogenetic relationships between the Guizhou Dong population and other comparison populations. Methods Based on the allele profile of 44 Y-markers in the Guizhou Dong group, we estimate their allele frequencies and haplotype frequencies. In addition, we also compare the forensic application efficiency of different Y-STR sets in the Guizhou Dong group. Finally, genetic relationships among Guizhou Dong and other reference populations are dissected by the multi-dimensional scaling and the phylogenetic tree. Results A total of 393 alleles are observed in 312 Guizhou Dong individuals for these Y-markers, with allele frequencies ranging from 0.0032 to 0.9679. The haplotype diversity and discriminatory capacity for these Y-markers in the Guizhou Dong population are 0.99984 and 0.97440, respectively. The population genetic analyses of the Guizhou Dong group and other reference populations show that the Guizhou Dong group has the closest genetic relationship with the Hunan Dong population, and followed by the Guizhou Tujia population. Conclusions In conclusion, these 44 Y-markers can be used as an effective tool for male differentiation in the Guizhou Dong group. The haplotype data in this study not only enrich the Y-STR data of different ethnic groups in China, but also have important significance for population genetics and forensic research.
Keywords	Guizhou Dong ; Forensic features ; Population genetics ; STR ; Y-chromosome ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	590
Language	English
Publishing date	2023-09-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genetic features and phylogenetic relationship analyses of Guizhou Han population residing in Southwest China via 38 X-InDels

Yuhang Feng / Ting Wang / Yunteng Yang / Jiangtao You / Kun He / Hongling Zhang / Qiyan Wang / Meiqing Yang / Jiang Huang / Zheng Ren / Xiaoye Jin

PeerJ, Vol 11, p e

2023 Volume 14964

Abstract: Background The insertion/deletion polymorphism (InDel), an ideal forensic genetic marker with a low spontaneous mutation rate and small amplification product fragments, is widely distributed in the genome, combining the advantages of STR and SNP genetic ... ...

Abstract	Background The insertion/deletion polymorphism (InDel), an ideal forensic genetic marker with a low spontaneous mutation rate and small amplification product fragments, is widely distributed in the genome, combining the advantages of STR and SNP genetic markers. The X-chromosome has high application value in complex paternity testing, and it is an excellent system for evaluating population admixture and studying evolutionary anthropology. However, further research is needed on the population genetics of X-chromosome InDels (X-InDels). Methods In this article, a system composed of 38 X-InDel loci was utilized to analyse and evaluate the forensic parameters of the Guizhou Han population in order to explore its forensic application efficiency. Results The results showed that expected heterozygosities spanned from 0.0189 to 0.5715, and the cumulative power of discrimination of the 32 X-InDels and three linkage blocks was 0.9999999954 and 0.999999999999741 for males and females, respectively. The combined mean exclusion chance of these loci for trios and duos is 0.999999 and 0.999747, respectively. Multiple methods like principal component analysis, Fst genetic distance, and phylogenetic reconstruction were employed for dissecting the genetic structure of the Guizhou Han population by comparing it with previously reported populations. As expected, the studied Han population displayed relatively close genetic affinities with the East Asian populations. At the same time, there were obvious genetic differentiations between the Guizhou Han population and other continental populations that were discerned, especially for the African populations. Conclusions This study further verified the applicability of 38 X-InDels for human personal identification and kinship analyses of Han Chinese, and also showed the application potential of X-InDels in population genetics.
Keywords	Guizhou Han ; Forensic features ; Population genetics ; InDel ; X-chromosome ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	590
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: An interpretation of the genetic polymorphism and population genetic background of Ankang Han population via a novel InDel panel

Wei Cui / Xiaoye Jin / Yating Fang / Qiong Lan / Jiangwei Lan / Man Chen / Shuyan Mei / Tong Xie / Bofeng Zhu

Forensic Sciences Research, Vol 0, Iss 0, Pp 1-

2021 Volume 8

Abstract: In this research, genotyping data of 43 InDel loci in 311 Han individuals in Ankang city, Shaanxi province, China were detected using a self-developed five-dye multiplex amplification panel. The allelic frequencies and forensic parameters of all InDel ... ...

Abstract	In this research, genotyping data of 43 InDel loci in 311 Han individuals in Ankang city, Shaanxi province, China were detected using a self-developed five-dye multiplex amplification panel. The allelic frequencies and forensic parameters of all InDel loci were calculated. The combined power of discrimination and probability of exclusion values were 0.999 999 999 999 999 998 827 39 and 0.999 887 424, respectively, which demonstrated that this 43-InDel panel was powerful for individual identifications in Ankang Han population. Moreover, genetic distances, pairwise FST values, principal component analyses, phylogenetic trees and STRUCTURE analyses were performed to investigate the genetic affinities between Ankang Han and reference groups. Population genetic investigations indicated that Ankang Han population had a close genetic relationship with Southern Han population compared with other reference groups.
Keywords	forensic sciences ; forensic genetics ; forensic parameter ; indel ; population genetics ; ankang han population ; Criminal law and procedure ; K5000-5582 ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2021-10-01T00:00:00Z
Publisher	Taylor & Francis Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Comprehensive analyses for genetic diversities of 19 autosomal STRs in Chinese Kazak group and its phylogenetic relationships with other continental populations

Yijie Wang / Xiaoye Jin / Wenqing Zhang / Wei Cui / Tingting Kong / Chong Chen / Yuxin Guo / Haotian Meng / Bofeng Zhu

Forensic Sciences Research, Vol 0, Iss 0, Pp 1-

2020 Volume 9

Abstract: Short tandem repeats (STRs) play an essential role in forensic genetics due to their high degree of polymorphisms, wide distributions and easy detection method. In this study, allelic frequencies and forensic statistical parameters of the 19 autosomal ... ...

Abstract	Short tandem repeats (STRs) play an essential role in forensic genetics due to their high degree of polymorphisms, wide distributions and easy detection method. In this study, allelic frequencies and forensic statistical parameters of the 19 autosomal STR loci in a Kazak ethnic group were calculated, and its genetic relationships with reference populations were assessed in order to understand population structure better and enrich population genetic data for forensic practice in Chinese Kazak ethnic group. There were 226 identified alleles with the corresponding allelic frequencies ranging from 0.0008 to 0.5295 in the 628 unrelated healthy Kazak individuals in Xinjiang Uygur Autonomous Region. All autosomal STRs were conformed to the Hardy-Weinberg equilibrium after Bonferroni’s correction. The cumulative power of discrimination and the combined probability of exclusion of all the 19 autosomal STRs were 0.999 999 999 999 999 999 999 997 162 and 0.999 999 994 484, respectively. Furthermore, the DA distances and Fixation index values of pairwise populations, principal component analysis, multidimensional scaling analysis, phylogenetic tree analysis and structure analysis were conducted to probe the genetic relationships between the Kazak group and other reference populations. The population genetic results showed that these 19 autosomal STR loci were characterised by high genetic diversities in the Kazak group. Furthermore, the studied Kazak group had close genetic relationships with the Uyghur group and the Uzbek group. The present results may facilitate understanding the genetic background of the Chinese Xinjiang Kazak group.
Keywords	forensic sciences ; forensic genetics ; kazak ethnic group ; autosomal strs ; population genetics ; interpopulation differentiation ; phylogenetic reconstruction ; Criminal law and procedure ; K5000-5582 ; Public aspects of medicine ; RA1-1270
Subject code	590
Language	English
Publishing date	2020-05-01T00:00:00Z
Publisher	Taylor & Francis Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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