Article: 新型冠状病毒感染流行背景下的儿童多系统炎症综合征.
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics
2024 Volume 26, Issue 1, Page(s) 98–102
Abstract: Multisystem inflammatory syndrome in children (MIS-C) is a complex syndrome characterized by multi-organ involvement that has emerged in the context of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak. The clinical presentation ... ...
| Title translation | Multisystem inflammatory syndrome in children in the context of coronavirus disease 2019 pandemic. |
|---|---|
| Abstract | Multisystem inflammatory syndrome in children (MIS-C) is a complex syndrome characterized by multi-organ involvement that has emerged in the context of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak. The clinical presentation of MIS-C is similar to Kawasaki disease but predominantly presents with fever and gastrointestinal symptoms, and severe cases can involve toxic shock and cardiac dysfunction. Epidemiological findings indicate that the majority of MIS-C patients test positive for SARS-CoV-2 antibodies. The pathogenesis and pathophysiology of MIS-C remain unclear, though immune dysregulation following SARS-CoV-2 infection is considered a major contributing factor. Current treatment approaches for MIS-C primarily involve intravenous immunoglobulin therapy and symptomatic supportive care. This review article provides a comprehensive overview of the definition, epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of MIS-C. |
| MeSH term(s) | Child ; Humans ; COVID-19 ; SARS-CoV-2 ; Pandemics ; Systemic Inflammatory Response Syndrome/diagnosis ; Systemic Inflammatory Response Syndrome/therapy |
| Language | Chinese |
| Publishing date | 2024-01-25 |
| Publishing country | China |
| Document type | Review ; English Abstract ; Journal Article |
| ISSN | 1008-8830 |
| ISSN | 1008-8830 |
| DOI | 10.7499/j.issn.1008-8830.2306093 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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