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  1. Article: [Research advances on common detection biomarkers and methodology of children's growth and development assessment].

    Li, J / Xie, X B

    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

    2022  Volume 56, Issue 9, Page(s) 1211–1217

    Abstract: With the rapid dissemination of information in modern society, Chinese residents pay more attention to the scientific concept of childcare, which makes the child prevention and health care industry develop rapidly. The law of children's growth and ... ...

    Abstract With the rapid dissemination of information in modern society, Chinese residents pay more attention to the scientific concept of childcare, which makes the child prevention and health care industry develop rapidly. The law of children's growth and development is extremely complex, so it is necessary to detect different biomarkers according to different growth and development evaluation angles. Human growth hormone(hGH), insulin-like growth factor-1(IGF-1), insulin-like growth factor binding protein-3(IGFBP-3), thyroid hormone, sex hormone, anti-müllerian hormone(AMH) and 25-hydroxy vitamin D(25-OH VD) are common biomarkers to monitor children's growth and development. This article aims to explain the concept and characteristics of common biomarkers of growth and development, summarize the detection methods of common biomarkers of growth and development evaluation developed in recent years, and provide a reference for children's prevention and health care to select appropriate detection biomarkers.
    MeSH term(s) Anti-Mullerian Hormone/metabolism ; Biomarkers ; Child ; Growth and Development ; Human Growth Hormone/metabolism ; Humans ; Insulin-Like Growth Factor Binding Protein 3 ; Insulin-Like Growth Factor I/metabolism ; Thyroid Hormones ; Vitamin D
    Chemical Substances Biomarkers ; Insulin-Like Growth Factor Binding Protein 3 ; Thyroid Hormones ; Human Growth Hormone (12629-01-5) ; Vitamin D (1406-16-2) ; Insulin-Like Growth Factor I (67763-96-6) ; Anti-Mullerian Hormone (80497-65-0)
    Language Chinese
    Publishing date 2022-10-07
    Publishing country China
    Document type Journal Article
    ZDB-ID 604575-3
    ISSN 0253-9624
    ISSN 0253-9624
    DOI 10.3760/cma.j.cn112150-20220515-00484
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Hepatic sinusoidal obstruction syndrome in a child].

    Zhang, X Y / Li, L T / Wang, J S / Xie, X B

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2022  Volume 60, Issue 3, Page(s) 246–247

    MeSH term(s) Child ; Hepatic Veno-Occlusive Disease/diagnosis ; Hepatic Veno-Occlusive Disease/etiology ; Humans
    Language Chinese
    Publishing date 2022-03-03
    Publishing country China
    Document type Journal Article
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.cn112140-20210718-00589
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Research progress of common respiratory virus receptor binding sites].

    Peng, H Z / Li, J / Li, Y H / Xu, Y Q / Peng, J Q / Xie, X B

    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

    2024  Volume 57, Issue 12, Page(s) 2212–2219

    Abstract: Respiratory viral infections are an important public health problem worldwide, with complex mechanisms of infection, and the key to infection lies in the specific binding between respiratory viruses and receptors. This article provides an overview of the ...

    Abstract Respiratory viral infections are an important public health problem worldwide, with complex mechanisms of infection, and the key to infection lies in the specific binding between respiratory viruses and receptors. This article provides an overview of the progress in the study of receptors for respiratory viruses, such as coronavirus and influenza virus (IV), with a focus on the binding sites of receptors such as angiotensin-converting enzyme 2 (ACE2) and sialic acid (SA) to respiratory viruses and the role of receptor diversity in respiratory viral infections. An in-depth study of the binding sites between viruses and receptors will help to understand the molecular mechanism of respiratory viral infections and provide a theoretical basis for disease prevention and control and the development of new therapeutic targets.
    MeSH term(s) Humans ; Binding Sites ; Coronavirus Infections ; N-Acetylneuraminic Acid ; Viruses ; Receptors, Virus
    Chemical Substances N-Acetylneuraminic Acid (GZP2782OP0) ; Receptors, Virus
    Language Chinese
    Publishing date 2024-01-08
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 604575-3
    ISSN 0253-9624
    ISSN 0253-9624
    DOI 10.3760/cma.j.cn112150-20230911-00175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Transient infantile hypertriglyceridemia caused by GPD1 deficiency: report of two cases and literature review].

    Xie, X B / Li, M P / Wang, J S

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2020  Volume 58, Issue 11, Page(s) 923–927

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Child ; Fatty Liver ; Female ; Glycerolphosphate Dehydrogenase/genetics ; Glycerophosphates ; Humans ; Hypertriglyceridemia/genetics ; Infant ; Male ; Retrospective Studies
    Chemical Substances Glycerophosphates ; Glycerolphosphate Dehydrogenase (EC 1.1.-)
    Language Chinese
    Publishing date 2020-10-12
    Publishing country China
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.cn112140-20200411-00375
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [On detection of chromogranin A, synaptophysin, neuronspecific enolase and progastrin-releasing peptide in small cell lung cancer].

    Lu, Q Q / Li, J / Li, Y H / Liu, H / Xie, X B

    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

    2022  Volume 56, Issue 7, Page(s) 1017–1022

    Abstract: Lung cancer is one of the most common cancer, there is a significant difference between the treatment and prognosis of small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). SCLC tumor cells usually express neuroendocrine tumor (NET) ... ...

    Abstract Lung cancer is one of the most common cancer, there is a significant difference between the treatment and prognosis of small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). SCLC tumor cells usually express neuroendocrine tumor (NET) markers, among which there are many studies on chromogranin A (CgA), synaptophysin (Syn), neuronspecific enolase (NSE) and pro-gastrin-releasing peptide (Pro-GRP) with SCLC. The levels of CgA, NSE and pro-GRP were related to the stage of SCLC, which were significantly higher in patients with extensive stage than in patients with limited stage, and their expression was significantly correlated with lower survival rate. Syn as an auxiliary diagnostic index of SCLC is more sensitive than CgA, and has high practical value in the differential diagnosis of SCLC and poorly differentiated squamous cell carcinoma; NSE is the most commonly used tumor marker in SCLC; Pro-GRP has stronger diagnostic advantages than CEA and NSE in distinguishing SCLC from NSCLC. Although these net markers are not specific markers of SCLC, their combined use with each others or combined with CT as an auxiliary diagnostic index may improve the level of differential diagnosis of SCLC, and they have a certain value in the staging of the disease, which is very important for the formulation of SCLC treatment strategy, their detection is conducive to the prevention and control of the disease.
    MeSH term(s) Biomarkers, Tumor ; Carcinoma, Non-Small-Cell Lung/pathology ; Chromogranin A ; Gastrins ; Humans ; Lung Neoplasms/diagnosis ; Lung Neoplasms/pathology ; Peptide Fragments ; Phosphopyruvate Hydratase ; Protein Precursors ; Small Cell Lung Carcinoma/diagnosis ; Small Cell Lung Carcinoma/pathology ; Synaptophysin
    Chemical Substances Biomarkers, Tumor ; Chromogranin A ; Gastrins ; Peptide Fragments ; Protein Precursors ; Synaptophysin ; big gastrin (3BL184GALN) ; Phosphopyruvate Hydratase (EC 4.2.1.11)
    Language Chinese
    Publishing date 2022-07-22
    Publishing country China
    Document type Journal Article
    ZDB-ID 604575-3
    ISSN 0253-9624
    ISSN 0253-9624
    DOI 10.3760/cma.j.cn112150-20220106-00022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: High‐Precision Relocation With the Burial Depths of the North Korean Underground Nuclear Explosions by Combining Pn and Pg Differential Traveltimes

    Yang, G. / Zhao, L. F. / Xie, X. B. / Zhang, L. / Yao, Z. X.

    Journal of geophysical research. 2021 June, v. 126, no. 6

    2021  

    Abstract: In seismic nuclear monitoring, an accurate source depth is an important prerequisite for reliably estimating the explosive yield. Relative location methods are often used for this purpose. However, the conventional method based on regional Pn waves ... ...

    Abstract In seismic nuclear monitoring, an accurate source depth is an important prerequisite for reliably estimating the explosive yield. Relative location methods are often used for this purpose. However, the conventional method based on regional Pn waves usually fails to give satisfactory constraints on the source depth, mainly due to the strong trade‐off between the burial depth and origin time. This study explores a high‐precision relative location method to simultaneously determine the relative epicenter and source elevation by using differential traveltimes from both downward‐takeoff Pn waves and horizontal‐takeoff Pg waves. The properties of both Pg and Pn waves, including the consistency between waveforms, the reliability of differential traveltime measurements, and their sensitivities to epicenter and depth variations, are investigated. By jointly applying both types of waveform data, the proposed method significantly enhances the constraint on the source depth variation. This method is applied to regional seismic data collected from China, South Korea, and Japan to determine the relative epicenters, origin times and relative burial depths of six North Korean underground nuclear explosions. The source depths are then used to provide burial‐depth corrections to estimate the explosive yields. The depths of the six North Korean nuclear explosions detonated on October 2006, May 2009, February 2013, January 2016, September 2016, and September 2017 are determined to be 330, 540, 506, 468, 521, and 570 m, respectively, and their yields after burial depth corrections are 1.6, 5.7, 13.4, 12.6, 21.7, and 225.7 kt, respectively.
    Keywords Japan ; geophysics ; research ; China ; South Korea
    Language English
    Dates of publication 2021-06
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ISSN 2169-9313
    DOI 10.1029/2020JB020745
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: [Digital loop-mediated isothermal amplification detection technology and its application progress].

    Huang, J / Li, P / Shi, S J / Li, Y H / Xie, X B

    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

    2021  Volume 55, Issue 12, Page(s) 1518–1523

    Abstract: Digital loop-mediated isothermal amplification (digital LAMP, dLAMP) is a novel nucleic acid amplification technique developed in recent years. It divides the target nucleic acid and LAMP reagent into a large number of independent detection regions, and ... ...

    Abstract Digital loop-mediated isothermal amplification (digital LAMP, dLAMP) is a novel nucleic acid amplification technique developed in recent years. It divides the target nucleic acid and LAMP reagent into a large number of independent detection regions, and uses a highly active chain replacement DNA polymerase and four specially designed primers for rapid amplification under isothermal conditions, which provides a good platform for quantitative detection of target nucleic acids. The advantages of high accuracy, high sensitivity, absolute quantification, high tolerance to inhibitors and simple instrumentation make the dLAMP technique very promising in molecular diagnosis, especially in rapid detection of pathogenic microorganisms, it shows a good application prospect in the fields of clinical diagnosis, food safety and environmental monitoring. Certainly, the development of dLAMP still faces some challenges, such as how to avoid non-specific amplification in multiple primer designs, multi-target nucleic acids and simultaneous detection of a large number of samples. With the development of dLAMP technology, this technology will greatly enrich the future development of molecular diagnostics. Applying rapid and effective molecular diagnostic techniques to the diagnosis of pathogenic microorganisms has important social significance for disease prevention and control.
    MeSH term(s) Humans ; Molecular Diagnostic Techniques ; Nucleic Acid Amplification Techniques ; Sensitivity and Specificity ; Technology
    Language Chinese
    Publishing date 2021-12-28
    Publishing country China
    Document type Journal Article
    ZDB-ID 604575-3
    ISSN 0253-9624
    ISSN 0253-9624
    DOI 10.3760/cma.j.cn112150-20210831-00850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Classical form of galactosemia: 4 cases].

    Liu, P / Lu, Y / Xie, X B / Kuerbanjiang, Abuduxikuer / Wang, J S

    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology

    2020  Volume 28, Issue 1, Page(s) 77–79

    MeSH term(s) Child ; Galactosemias/diagnosis ; Humans
    Language Chinese
    Publishing date 2020-01-21
    Publishing country China
    Document type Case Reports ; Journal Article
    ISSN 1007-3418
    ISSN 1007-3418
    DOI 10.3760/cma.j.issn.1007-3418.2020.01.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Progress in research of allergen detection methods].

    Mao, J / Lu, Q Q / Zeng, X / Li, P / Shi, S J / Li, J / Zhu, Z H / Xie, X B / Lu, Q

    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

    2021  Volume 55, Issue 1, Page(s) 123–129

    Abstract: Allergic diseases have continued to increase year by year causing serious physical and mental injury to patients, families and individuals. This increase has been driven by conventional environmental and nutritional changes but is also created by the ... ...

    Abstract Allergic diseases have continued to increase year by year causing serious physical and mental injury to patients, families and individuals. This increase has been driven by conventional environmental and nutritional changes but is also created by the continual introduction of food additives into the diet and novel interior decoration materials into the living space. The causes of allergic diseases are complex and diverse, and the medical laboratory often is not be able to identify the allergic trigger; this creates a difficult environment to identify the appropriate clinical treatment for disease prevention and control. Physicians must be able to identify these triggers to help patients avoid the underlying allergenic cause of their disease. This can only be done by actively knowing a patient's medical history, identifying the clinical manifestations of hypersensitivity and utilizing confirmatory testing as an important clinical tool in identifying the allergic source.
    MeSH term(s) Allergens ; Diet ; Food Hypersensitivity/diagnosis ; Humans ; Hypersensitivity/diagnosis
    Chemical Substances Allergens
    Language Chinese
    Publishing date 2021-01-17
    Publishing country China
    Document type Journal Article
    ZDB-ID 604575-3
    ISSN 0253-9624
    ISSN 0253-9624
    DOI 10.3760/cma.j.cn112150-20200716-01019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Relationship between phenotype and genotype of ABCB11 deficiency in siblings and literature review].

    Peng, X R / Lu, Y / Zhang, M H / Li, L T / Xie, X B / Gong, J Y / Wang, J S

    Zhonghua er ke za zhi = Chinese journal of pediatrics

    2018  Volume 56, Issue 6, Page(s) 440–444

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) ATP Binding Cassette Transporter, Subfamily B, Member 11/deficiency ; ATP Binding Cassette Transporter, Subfamily B, Member 11/genetics ; ATP-Binding Cassette Transporters ; Child ; Cholestasis, Intrahepatic ; Genotype ; Humans ; Infant ; Male ; Phenotype ; Retrospective Studies ; Siblings
    Chemical Substances ABCB11 protein, human ; ATP Binding Cassette Transporter, Subfamily B, Member 11 ; ATP-Binding Cassette Transporters
    Language Chinese
    Publishing date 2018-06-09
    Publishing country China
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 784523-6
    ISSN 0578-1310
    ISSN 0578-1310
    DOI 10.3760/cma.j.issn.0578-1310.2018.06.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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