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Article: [Establishment of early warning indicators of SARS-CoV-2 Omicron variant in Tianjin].

Zhang, Y / Zhou, N / Zhou, P / Xie, X H / Li, J M

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

2023 Volume 57, Issue 1, Page(s) 48–51

Abstract: In this study, Delphi method was used to conduct a questionnaire survey on 12 experts to determine the indicators system and the corresponding weight for early warning features of SARS-CoV-2 Omicron in Tianjin.The positive indexes of experts in three ... ...

Abstract	In this study, Delphi method was used to conduct a questionnaire survey on 12 experts to determine the indicators system and the corresponding weight for early warning features of SARS-CoV-2 Omicron in Tianjin.The positive indexes of experts in three rounds of consultations were both 100%. The experts' authority coefficient was 0.79. The Kendall's W coordination coefficients were 0.375, 0.356 and 0.385 respectively (all
MeSH term(s)	Humans ; SARS-CoV-2 ; Delphi Technique ; COVID-19 ; Surveys and Questionnaires
Language	Chinese
Publishing date	2023-01-13
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	604575-3
ISSN	0253-9624
ISSN	0253-9624
DOI	10.3760/cma.j.cn112150-20220802-00771
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Article: [CXCL5 inhibits tumor immune of lung cancer via modulating PD1/PD-L1 signaling].

Xie, X H / Wang, Y J / Lei, W / Gao, H J / Duan, Y J / Hou, X

Zhonghua zhong liu za zhi [Chinese journal of oncology

2022 Volume 44, Issue 5, Page(s) 382–388

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Animals ; B7-H1 Antigen/metabolism ; CD8-Positive T-Lymphocytes ; Chemokine CXCL5/metabolism ; Humans ; Lung Neoplasms/immunology ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Mice ; Mice, Inbred C57BL ; Programmed Cell Death 1 Receptor/metabolism
Chemical Substances	B7-H1 Antigen ; CXCL5 protein, human ; Chemokine CXCL5 ; PDCD1 protein, human ; Programmed Cell Death 1 Receptor
Language	Chinese
Publishing date	2022-05-25
Publishing country	China
Document type	Journal Article
ZDB-ID	603424-x
ISSN	0253-3766
ISSN	0253-3766
DOI	10.3760/cma.j.cn112152-20200223-00118
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Article: [Analysis of adverse pregnancy outcomes and related factors in pregnant women with syphilis infection in Guangxi of China, 2014-2018].

Qin, Q H / Xie, X H / Yao, H / Qiu, X X / Xia, H W / Wang, Q

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine

2019 Volume 53, Issue 12, Page(s) 1284–1289

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Adult ; China/epidemiology ; Female ; Humans ; Infectious Disease Transmission, Vertical/statistics & numerical data ; Middle Aged ; Pregnancy ; Pregnancy Complications, Infectious/microbiology ; Pregnancy Outcome/epidemiology ; Syphilis/complications ; Syphilis/diagnosis ; Syphilis/epidemiology
Language	Chinese
Publishing date	2019-11-29
Publishing country	China
Document type	Journal Article
ZDB-ID	604575-3
ISSN	0253-9624
ISSN	0253-9624
DOI	10.3760/cma.j.issn.0253-9624.2019.12.015
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Article: [Clinical report of hoding cricoarytenoid joint reduction with visual laryngoscope under intravenous anesthesia].

Lu, Y Y / Zhang, Y H / Yu, L X / Zeng, X M / Yang, C Z / Ma, Y L / Zhou, L J / Hu, H Y / Xie, X H / Yu, Z K

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

2022 Volume 57, Issue 9, Page(s) 1095–1101

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Anesthesia, Intravenous/adverse effects ; Arytenoid Cartilage/injuries ; Female ; Humans ; Intubation, Intratracheal/adverse effects ; Joint Dislocations/etiology ; Joint Dislocations/therapy ; Laryngeal Diseases/etiology ; Laryngoscopes/adverse effects ; Male ; Middle Aged ; Retrospective Studies
Language	Chinese
Publishing date	2022-09-20
Publishing country	China
Document type	Journal Article
ZDB-ID	2195655-8
ISSN	1673-0860
ISSN	1673-0860
DOI	10.3760/cma.j.cn115330-20220221-00076
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Article: [Exploration of the treatment model for patients with advanced non-small cell lung cancer complicated with chronic obstructive pulmonary disease based on real-world data].

Wang, F / Xie, X H / Lin, X Q / Qin, Y Y / Xie, Z H / Zhang, J X / Ouyang, M / Zhou, C Z

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases

2020 Volume 43, Issue 5, Page(s) 450–454

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Aged ; Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung/complications ; Carcinoma, Non-Small-Cell Lung/therapy ; Disease-Free Survival ; Female ; Humans ; Lung Neoplasms/complications ; Lung Neoplasms/therapy ; Male ; Middle Aged ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/therapy ; Retrospective Studies ; Treatment Outcome
Language	Chinese
Publishing date	2020-05-25
Publishing country	China
Document type	Journal Article
ZDB-ID	1027965-9
ISSN	1001-0939
ISSN	1001-0939
DOI	10.3760/cma.j.cn112147-20200304-00241
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Zs.B 2465: Show issues

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Article ; Online: HCCS1 inhibits the stemness of human pancreatic cancer stem-like cells.

Xie, X-H / Chen, Y-R / Jin, S / Ma, Y-S / Tian, X-D / Yang, Y-M

European review for medical and pharmacological sciences

2019 Volume 23, Issue 5, Page(s) 2125–2131

Abstract: Objective: SW1990-spheroid enrichment (SW1990-SE) cells were isolated using a new type of consecutive spheroid enrichment in this study. Cell surface markers were determined by flow cytometry for identification. In vivo tumorigenicity was applied by ... ...

Abstract	Objective: SW1990-spheroid enrichment (SW1990-SE) cells were isolated using a new type of consecutive spheroid enrichment in this study. Cell surface markers were determined by flow cytometry for identification. In vivo tumorigenicity was applied by subcutaneous transplantation in nude mice for verifying the stemness characteristics of SW1990-SE cells. Materials and methods: SW1990-SE cells were subjected to lentivirus infection for establishing the SW1990-SE cell line stably low-expressing HCCS1 (SW1990-SE-shHCCS1) and negative control cell line (SW1990-SE-LV3NC). The stemness regulatory effects of HCCS1 on SW1990-SE cells were evaluated by cell counting kit-8 (CCK-8) assay and 96-wells plate single cell cloning assay in vitro. Subcutaneous transplantation in nude mice was conducted for evaluating the in vivo stemness regulation of HCCS1 on SW1990-SE cells.. Results: HCCS1 knockdown in SW1990-SE cells did not markedly change the cell proliferation and doubling time, whereas the in vitro spheroid diameter and single cell cloning efficacy remarkably increased. In vivo experiments showed that HCCS1 knockdown greatly enhanced the tumorigenicity of SW1990-SE cells in nude mice. Conclusions: This study first obtains the human pancreatic cancer stem-like cells SW1990-SE through consecutive spheroid enrichment. Both in vivo and in vitro experiments verified that HCCS1 knockdown largely enhanced the stemness of SW1990-SE cells. Our study provides an important reference for the research of tumor stem cells.
MeSH term(s)	Animals ; Cell Culture Techniques ; Cell Line, Tumor ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Mice ; Mice, Nude ; Neoplasm Transplantation ; Neoplastic Stem Cells/metabolism ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/pathology ; Spheroids, Cellular/cytology ; Spheroids, Cellular/pathology ; Vesicular Transport Proteins/genetics ; Vesicular Transport Proteins/metabolism
Chemical Substances	VPS53 protein, human ; Vesicular Transport Proteins
Language	English
Publishing date	2019-03-20
Publishing country	Italy
Document type	Journal Article
ZDB-ID	605550-3
ISSN	2284-0729 ; 1128-3602 ; 0392-291X
ISSN (online)	2284-0729
ISSN	1128-3602 ; 0392-291X
DOI	10.26355/eurrev_201903_17256
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Zs.A 1887: Show issues

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Article: [The correlation study on human respiratory syncytial virus daily incidence and meteorological parameters in the main urban area of Chongqing from 2009 to 2019].

Liu, X Y / Long, X / Zhai, H / Chen, S Y / Deng, Y / Xie, X H / Zang, N / Xie, J / Luo, Z X / Luo, J / Li, Q B / Fu, Z / Ren, L / Liu, E M

Zhonghua yi xue za zhi

2021 Volume 101, Issue 36, Page(s) 2878–2884

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Child ; China/epidemiology ; Correlation of Data ; Female ; Humans ; Incidence ; Infant ; Male ; Respiratory Syncytial Virus Infections/epidemiology ; Respiratory Syncytial Virus, Human ; Respiratory Tract Infections
Language	Chinese
Publishing date	2021-09-28
Publishing country	China
Document type	Journal Article
ZDB-ID	132513-9
ISSN	0376-2491
ISSN	0376-2491
DOI	10.3760/cma.j.cn112137-20210223-00470
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Article ; Online: Cantharidin suppressed breast cancer MDA-MB-231 cell growth and migration by inhibiting MAPK signaling pathway.

Gu, X-D / Xu, L-L / Zhao, H / Gu, J-Z / Xie, X-H

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas

2017 Volume 50, Issue 7, Page(s) e5920

Abstract: As an active constituent of the beetle Mylabris used in traditional Chinese medicine, cantharidin is a potent and selective inhibitor of protein phosphatase 2A (PP2A) that plays a crucial role in cell cycle progression, apoptosis, and cell fate. The role ...

Abstract	As an active constituent of the beetle Mylabris used in traditional Chinese medicine, cantharidin is a potent and selective inhibitor of protein phosphatase 2A (PP2A) that plays a crucial role in cell cycle progression, apoptosis, and cell fate. The role and possible mechanisms exerted by cantharidin in cell growth and metastasis of breast cancer were investigated in this study. Cantharidin was found to inhibit cell viability and clonogenic potential in a time- and dose-dependent manner. Cell cycle analysis revealed that cell percentage in G2/M phase decreased, whereas cells in S and G1 phases progressively accumulated with the increasing doses of cantharidin treatment. In a xenograft model of breast cancer, cantharidin inhibited tumor growth in a dose-dependent manner. Moreover, high doses of cantharidin treatment inhibited cell migration in wound and healing assay and downregulated protein levels of major matrix metalloproteinases (MMP)-2 and MMP-9. MDA-MB-231 cell migration and invasion were dose-dependently inhibited by cantharidin treatment. Interestingly, the members of the mitogen-activated protein kinase (MAPK) signaling family were less phosphorylated as the cantharidin dose increased. Cantharidin was hypothesized to exert its anticancer effect through the MAPK signaling pathway. The data of this study also highlighted the possibility of using PP2A as a therapeutic target for breast cancer treatment.
Language	English
Publishing date	2017-07-03
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	786234-9
ISSN	1414-431X ; 0100-879X
ISSN (online)	1414-431X
ISSN	0100-879X
DOI	10.1590/1414-431X20175920
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Zs.B 1359: Show issues

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Article: [Pharyngeal space carcinoma ex pleomorphic adenoma：a case report].

Jiang, Y L / Peng, H S / Wu, S H / Xie, X H / Zhu, X H / Liu, Y H

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery

2018 Volume 32, Issue 9, Page(s) 710–712

Abstract: Carcinoma ex pleomorphic adenoma is an epithelial malignant tumor of pleomorphic adenoma. This may be due to the accumulation of genetic instability caused by long-term pleomorphic adenomas. There are few reports of parapharyngeal space carcinoma ex ... ...

Abstract	Carcinoma ex pleomorphic adenoma is an epithelial malignant tumor of pleomorphic adenoma. This may be due to the accumulation of genetic instability caused by long-term pleomorphic adenomas. There are few reports of parapharyngeal space carcinoma ex pleomorphic adenoma in the literature study both at home and abroad. This article retrospectively summarized the clinical data of 1 case of pharyngeal space carcinoma ex pleomorphic adenoma and reviewed the literature. We strengthened the understanding of parapharyngeal space carcinoma ex pleomorphic adenoma, improve the accuracy of diagnosis and reduce misdiagnosis and mistreatment.
MeSH term(s)	Adenocarcinoma/diagnosis ; Adenoma, Pleomorphic/diagnosis ; Carcinoma ; Humans ; Pharyngeal Neoplasms/diagnosis ; Pharynx ; Retrospective Studies
Language	Chinese
Publishing date	2018-06-12
Publishing country	China
Document type	Case Reports ; Journal Article
ISSN	1001-1781
ISSN	1001-1781
DOI	10.13201/j.issn.1001-1781.2018.09.017
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Article ; Online: Statin therapy on glycemic control in type 2 diabetic patients: A network meta-analysis.

Cui, J Y / Zhou, R R / Han, S / Wang, T S / Wang, L Q / Xie, X H

Journal of clinical pharmacy and therapeutics

2018 Volume 43, Issue 4, Page(s) 556–570

Abstract: What is known and objective: Statins are the cornerstone of primary and secondary prevention of cardiovascular diseases (CVDs) and are effective for the prevention of vascular events in diabetic patients. Diabetes mellitus is an important risk factor ... ...

Abstract	What is known and objective: Statins are the cornerstone of primary and secondary prevention of cardiovascular diseases (CVDs) and are effective for the prevention of vascular events in diabetic patients. Diabetes mellitus is an important risk factor for CVDs .The majority of patients with diabetes mellitus benefits from statin therapy. According to the recent clinical guidelines of the American College of Cardiology and the American Heart Association, moderate-intensity or high-intensity statin therapy should be used as the primary prevention for individuals with diabetes mellitus, aged between 40 and 75 years and with low-density lipoprotein cholesterol (LDL-C) from 70 to 189 mg/dL. The objective of this review was to compare the associations of individual statins with their adverse effects on glycemic control in patients with type 2 diabetes mellitus (T2DM). Methods: MEDLINE, EMBASE and CENTRAL were searched from inception through March 2017. There were included randomized controlled trials comparing statins with placebo or active comparators in patients with T2DM. The endpoints of interest were glycated haemoglobin A1 Results: Twenty-three trials were included. A significant increase in HbA1c was detected in the pairwise meta-analysis when statins as a class were compared with placebo (SMD: 0.11). Moderate-intensity pitavastatin lowered HbA1c compared with moderate-intensity atorvastatin (SMD: -0.16), high-intensity atorvastatin (SMD: -0.77), moderate-intensity rosuvastatin (SMD: -0.16) and low-intensity pravastatin (SMD: -0.15). Moderate-intensity simvastatin lowered HbA1c compared with high-intensity rosuvastatin (SMD: -0.45) and high-intensity atorvastatin (SMD: -0.77). High-intensity atorvastatin elevated HbA1c compared with placebo (SMD: 0.63), moderate-intensity rosuvastatin (SMD: 0.50), low-intensity pravastatin (SMD: 0.51) and moderate-intensity atorvastatin (SMD: 0.50). Moderate-intensity pitavastatin has lowered FPG compared with placebo (SMD: -0.55), moderate-intensity rosuvastatin (SMD: -0.65), moderate-intensity atorvastatin (SMD: -0.65) and high-intensity atorvastatin (SMD: -1.25). High-intensity atorvastatin has elevated FPG compared with placebo (SMD: 0.70), moderate-intensity atorvastatin (SMD: 0.60), moderate-intensity rosuvastatin (SMD: 0.60) and moderate-intensity simvastatin (SMD: 0.90). What is new and conclusion: Statins were associated with an increase in HbA1c compared with placebo. In patients with T2DM, moderate-intensity pitavastatin improved the glycemic control whereas high-intensity atorvastatin worsened it. Appropriate statins should be administered for patients with diabetes mellitus.
MeSH term(s)	Adult ; Aged ; Blood Glucose/drug effects ; Cardiovascular Diseases/prevention & control ; Diabetes Mellitus, Type 2/drug therapy ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Middle Aged ; Network Meta-Analysis ; Risk Factors ; Secondary Prevention/methods
Chemical Substances	Blood Glucose ; Hydroxymethylglutaryl-CoA Reductase Inhibitors
Language	English
Publishing date	2018-05-07
Publishing country	England
Document type	Journal Article ; Meta-Analysis
ZDB-ID	639006-7
ISSN	1365-2710 ; 0269-4727
ISSN (online)	1365-2710
ISSN	0269-4727
DOI	10.1111/jcpt.12690
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