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  1. Article ; Online: Caseous Calcification of the Mitral Annulus.

    Xie, Xiao-Jun / Yu, Feng-Xu

    Radiology

    2023  Volume 309, Issue 1, Page(s) e231322

    MeSH term(s) Humans ; Calcinosis/diagnostic imaging ; Lymphatic Vessels ; Mitral Valve/diagnostic imaging
    Language English
    Publishing date 2023-10-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80324-8
    ISSN 1527-1315 ; 0033-8419
    ISSN (online) 1527-1315
    ISSN 0033-8419
    DOI 10.1148/radiol.231322
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  2. Article: Role of targeting ferroptosis as a component of combination therapy in combating drug resistance in colorectal cancer.

    Xie, Xiao-Ting / Pang, Qiang-Hu / Luo, Lian-Xiang

    World journal of clinical oncology

    2024  Volume 15, Issue 3, Page(s) 375–377

    Abstract: Colorectal cancer (CRC) is a form of cancer that is often resistant to chemotherapy, targeted therapy, radiotherapy, and immunotherapy due to its genomic instability and inflammatory tumor microenvironment. Ferroptosis, a type of non-apoptotic cell death, ...

    Abstract Colorectal cancer (CRC) is a form of cancer that is often resistant to chemotherapy, targeted therapy, radiotherapy, and immunotherapy due to its genomic instability and inflammatory tumor microenvironment. Ferroptosis, a type of non-apoptotic cell death, is characterized by the accumulation of iron and the oxidation of lipids. Studies have revealed that the levels of reactive oxygen species and glutathione in CRC cells are significantly lower than those in healthy colon cells. Erastin has emerged as a promising candidate for CRC treatment by diminishing stemness and chemoresistance. Moreover, the gut, responsible for regulating iron absorption and release, could influence CRC susceptibility through iron metabolism modulation. Investigation into ferroptosis offers new insights into CRC pathogenesis and clinical management, potentially revolutionizing treatment approaches for therapy-resistant cancers.
    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Editorial
    ZDB-ID 2587357-X
    ISSN 2218-4333
    ISSN 2218-4333
    DOI 10.5306/wjco.v15.i3.375
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  3. Article ; Online: Does Prophylactic Closure Improve Outcomes After Colorectal Endoscopic Submucosal Dissection? A Systematic Review and Meta-analysis.

    Dong, Liang / Zhu, Weihua / Zhang, Xiaolei / Xie, Xiao

    Surgical laparoscopy, endoscopy & percutaneous techniques

    2024  Volume 34, Issue 1, Page(s) 94–100

    Abstract: Background: Several studies have described prophylactic closure after endoscopic submucosal dissection (ESD) of colorectal lesions for improving postoperative outcomes. We reviewed the evidence on the impact of prophylactic closure after ESD.: Methods! ...

    Abstract Background: Several studies have described prophylactic closure after endoscopic submucosal dissection (ESD) of colorectal lesions for improving postoperative outcomes. We reviewed the evidence on the impact of prophylactic closure after ESD.
    Methods: A literature search was conducted on PubMed, Embase, CENTRAL, and Web of Science by 2 reviewers independently for studies published up to July 9, 2023. All types of comparative studies were eligible.
    Results: Ten studies compared 939 patients undergoing prophylactic closure with 1074 controls. Three were randomized controlled trials (RCTs) while the rest were observational. Pooled data from all included studies showed that prophylactic closure resulted in reduced incidence of delayed bleeding after ESD [odds ratio (OR): 0.30; 95% CI: 0.15, 0.72; I2 =0%]. These results were significant only for observational studies but not for RCTs. Meta-analysis showed no significant difference in the risk of delayed perforation (OR: 0.55; 95% CI: 0.18, 1.70; I2 =0%) or post-ESD coagulation syndrome (PECS) (OR: 1.15; 95% CI: 0.41, 3.19; I2 =63%) between closure and nonclosure groups.
    Conclusions: Observational data suggest that prophylactic closure of colorectal mucosal defects after ESD may reduce the risk of delayed bleeding. However, the results are not concurred by RCTs. Furthermore, there seems to be no impact of prophylactic closure on the risk of delayed perforation and PECS.
    MeSH term(s) Humans ; Endoscopic Mucosal Resection/adverse effects ; Colorectal Neoplasms/surgery ; Colorectal Neoplasms/pathology ; Retrospective Studies ; Treatment Outcome ; Incidence
    Language English
    Publishing date 2024-02-01
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 1475108-2
    ISSN 1534-4908 ; 1530-4515 ; 1051-7200
    ISSN (online) 1534-4908
    ISSN 1530-4515 ; 1051-7200
    DOI 10.1097/SLE.0000000000001248
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  4. Article ; Online: A multi-source molecular network representation model for protein-protein interactions prediction.

    Zou, Hai-Tao / Ji, Bo-Ya / Xie, Xiao-Lan

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 6184

    Abstract: The prediction of potential protein-protein interactions (PPIs) is a critical step in decoding diseases and understanding cellular mechanisms. Traditional biological experiments have identified plenty of potential PPIs in recent years, but this problem ... ...

    Abstract The prediction of potential protein-protein interactions (PPIs) is a critical step in decoding diseases and understanding cellular mechanisms. Traditional biological experiments have identified plenty of potential PPIs in recent years, but this problem is still far from being solved. Hence, there is urgent to develop computational models with good performance and high efficiency to predict potential PPIs. In this study, we propose a multi-source molecular network representation learning model (called MultiPPIs) to predict potential protein-protein interactions. Specifically, we first extract the protein sequence features according to the physicochemical properties of amino acids by utilizing the auto covariance method. Second, a multi-source association network is constructed by integrating the known associations among miRNAs, proteins, lncRNAs, drugs, and diseases. The graph representation learning method, DeepWalk, is adopted to extract the multisource association information of proteins with other biomolecules. In this way, the known protein-protein interaction pairs can be represented as a concatenation of the protein sequence and the multi-source association features of proteins. Finally, the Random Forest classifier and corresponding optimal parameters are used for training and prediction. In the results, MultiPPIs obtains an average 86.03% prediction accuracy with 82.69% sensitivity at the AUC of 93.03% under five-fold cross-validation. The experimental results indicate that MultiPPIs has a good prediction performance and provides valuable insights into the field of potential protein-protein interactions prediction. MultiPPIs is free available at https://github.com/jiboyalab/multiPPIs .
    MeSH term(s) Proteins/metabolism ; MicroRNAs ; Amino Acid Sequence ; Amino Acids ; RNA, Long Noncoding ; Computational Biology/methods
    Chemical Substances Proteins ; MicroRNAs ; Amino Acids ; RNA, Long Noncoding
    Language English
    Publishing date 2024-03-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-56286-w
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  5. Article ; Online: TFE3-RCC of the right kidney in an eight-year-old child.

    Wu, Yaoxing / Xie, Xiao Long / Xiang, Bo

    Asian journal of surgery

    2024  

    Language English
    Publishing date 2024-03-22
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2024.03.105
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  6. Article ; Online: A Semantics-aware Self-adaptive Associated Organization Method of GeoVideo Big Data

    XIE Xiao

    Acta Geodaetica et Cartographica Sinica, Vol 45, Iss 10, Pp 1260-

    2016  Volume 1260

    Keywords Mathematical geography. Cartography ; GA1-1776
    Language Chinese
    Publishing date 2016-10-01T00:00:00Z
    Publisher Surveying and Mapping Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Application of neodymium butadiene rubber BR 9101 N in the formula of support compound of run-flat tire

    XU Kai / XIE Xiao-hou / WANG Ai-sheng / CHEN Jian-jun

    Hecheng xiangjiao gongye, Vol 46, Iss 6, Pp 519-

    2024  Volume 524

    Abstract: The application of neodymium based cis-1,4-polybutadiene rubber (Nd-BR) BR 9101 N in the formula of support compound of run-flat tire was studied, and compared with those of foreign same type product Nd-BR CB 24. The results showed that Nd-BR BR 9101 N ... ...

    Abstract The application of neodymium based cis-1,4-polybutadiene rubber (Nd-BR) BR 9101 N in the formula of support compound of run-flat tire was studied, and compared with those of foreign same type product Nd-BR CB 24. The results showed that Nd-BR BR 9101 N could meet the requirements for incoming inspection of Nd-BR raw material, and the basic compounding performance could be met. When Nd-BR BR 9101 N was used in the formula of support compound of run-flat tire to replace Nd-BR CB 24 with the same amount, Mooney viscosity, scorch time and curing characteristics of the former compound, and physical and mechanical property of Nd-BR BR 9101 N vulcanizate before and after aging were basically the same to those of the latter, and the aging performance of the former improved, whereas the compression fatigue temperature rise and compression set all reduced compared with those of the latter. The high-speed durability of finished tire made from Nd-BR BR 9101 N was good and could meet the product design requirements and exceeded the national standard regulations, which were basically equivalent to those of the existing production tire, in addition, the strength performance and zero-pressure durability of finished tire made from Nd-BR BR 9101 N improved compared with those of the existing production tire.
    Keywords neodymium based cis-1 ; 4-polybutadiene rubbe ; run-flat tire ; support compound ; physical and mechanical property ; aging performance ; high-speed durability ; strength performance ; zero-pressure durability ; Organic chemistry ; QD241-441 ; Chemical engineering ; TP155-156 ; Chemicals: Manufacture ; use ; etc ; TP200-248
    Subject code 670
    Language Chinese
    Publishing date 2024-12-01T00:00:00Z
    Publisher Editorial Office of China Synthetic Rubber Industry
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Effect of hospital-community online management on medication management of elderly patients with peritoneal dialysis during COVID-19.

    Zhang, Chi / Wang, Jun-Sheng / Xie, Xiao-Hui

    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy

    2023  Volume 28, Issue 2, Page(s) 297–304

    Abstract: Introduction: The study aimed to explore feasibility and effect of hospital-community online management on the medication management of elderly peritoneal dialysis (PD) patients with end-stage renal disease (ESRD) during COVID-19.: Methods: A total ... ...

    Abstract Introduction: The study aimed to explore feasibility and effect of hospital-community online management on the medication management of elderly peritoneal dialysis (PD) patients with end-stage renal disease (ESRD) during COVID-19.
    Methods: A total of 160 patients receiving PD were randomly divided into the control (n = 80, outpatient follow-up management mode) and observation (n = 80, hospital-community online management mode) groups. The self-efficacy (General Self-Efficacy Scale [GSES]), medication adherence (8-item Morisky medication adherence scale [MMAS-8]), quality of life (kidney disease quality of life short form [KDQOL-SF]), and degree of depression (beck depression inventory [BDI]) before and after the intervention were compared.
    Results: After the intervention, the scores of GSES (4.20 ± 0.46 vs. 3.09 ± 0.33), MMAS-8 (5.82 ± 0.92 vs. 5.13 ± 1.25), and KDQOL-SF were significantly higher, whereas the BDI score (9.50 ± 2.86 vs. 12.08 ± 2.95) was significantly lower in the observation group than in the control group (p < 0.05).
    Conclusion: Hospital-community online management presents good effects in the medication management of PD patients with ESRD.
    MeSH term(s) Humans ; Aged ; Renal Dialysis ; Quality of Life ; Medication Therapy Management ; COVID-19/therapy ; Peritoneal Dialysis ; Kidney Failure, Chronic/therapy ; Kidney Diseases ; Hospitals
    Language English
    Publishing date 2023-10-24
    Publishing country Australia
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2119809-3
    ISSN 1744-9987 ; 1091-6660 ; 1744-9979
    ISSN (online) 1744-9987
    ISSN 1091-6660 ; 1744-9979
    DOI 10.1111/1744-9987.14077
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5208: Show issues Location:
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  9. Article ; Online: LOV thy neighbor: Mapping protein interactomes by genetically encodable photoproximity labeling.

    Xie, Xiao / Jiang, Yishu / Chang, Christopher J

    Proceedings of the National Academy of Sciences of the United States of America

    2023  Volume 120, Issue 20, Page(s) e2305211120

    MeSH term(s) Bacterial Proteins/metabolism ; Light
    Chemical Substances Bacterial Proteins
    Language English
    Publishing date 2023-05-08
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2305211120
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  10. Article ; Online: Giant right atrium due to dysplastic tricuspid valve in an infant.

    Li, Jin-Ping / Xie, Xiao-Jun / Yu, Feng-Xu

    Asian journal of surgery

    2023  Volume 46, Issue 7, Page(s) 2940–2941

    MeSH term(s) Humans ; Infant ; Tricuspid Valve/diagnostic imaging ; Tricuspid Valve/surgery ; Echocardiography ; Heart Defects, Congenital ; Heart Atria/diagnostic imaging
    Language English
    Publishing date 2023-02-16
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.02.016
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