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Article: Editorial: Quality and nutrition of meat and meat products: emphasis on muscle protein structure, activity, modification, and functionality.

Liu, Rui / Xing, Tong

2023 Volume 10, Page(s) 1301481

Language	English
Publishing date	2023-11-13
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	2776676-7
ISSN	2296-861X
ISSN	2296-861X
DOI	10.3389/fnut.2023.1301481
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Potential pathological and molecular mechanisms of temporomandibular joint osteoarthritis.

Juan, Zhang / Xing-Tong, Mu / Xu, Zhang / Chang-Yi, Li

Journal of dental sciences

2023 Volume 18, Issue 3, Page(s) 959–971

Abstract: Temporomandibular joint osteoarthritis (TMJ OA) is a progressive degenerative disease of the temporomandibular joint (TMJ). The unclear etiology and mechanisms of TMJ OA bring great difficulties to early diagnosis and effective treatment, causing ... ...

Abstract	Temporomandibular joint osteoarthritis (TMJ OA) is a progressive degenerative disease of the temporomandibular joint (TMJ). The unclear etiology and mechanisms of TMJ OA bring great difficulties to early diagnosis and effective treatment, causing enormous burdens to patients' life and social economics. In this narrative review, we summarized the main pathological changes of TMJ OA, including inflammatory responses, degeneration of extracellular matrix (ECM), abnormal cell biological behaviors (apoptosis, autophagy, and differentiation) in TMJ tissue, and aberrant angiogenesis. All pathological features are closely linked to each other, forming a vicious cycle in the process of TMJ OA, which results in prolonged disease duration and makes it difficult to cure. Various molecules and signaling pathways are involved in TMJ OA pathogenesis, including nuclear factor kappa-B (NF-κB), mitogen-activated protein kinases (MAPKs), extracellular regulated protein kinases (ERKs) and transforming growth factor (TGF)-β signaling pathways et al. One molecule or pathway can contribute to several pathological changes, and the crosstalk between different molecules and pathways can further lead to a complicated condition TMJ OA. TMJ OA has miscellaneous etiology, complex clinical status, depressed treatment results, and poor prognosis. Therefore, novel in-vivo and in-vitro models, novel medicine, materials, and approaches for therapeutic procedures might be helpful for further investigation of TMJ OA. Furthermore, the role of genetic factors in TMJ OA needs to be elucidated to establish more reasonable and effective clinical strategies for diagnosing and treating TMJ OA.
Language	English
Publishing date	2023-04-18
Publishing country	Netherlands
Document type	Journal Article ; Review
ISSN	2213-8862
ISSN (online)	2213-8862
DOI	10.1016/j.jds.2023.04.002
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Article: Effects of Wooden Breast Myopathy on Meat Quality Characteristics of Broiler Pectoralis Major Muscle and Its Changes with Intramuscular Connective Tissue.

Bian, Tianjiao / Xing, Tong / Zhao, Xue / Xu, Xinglian

Foods (Basel, Switzerland)

2024 Volume 13, Issue 4

Abstract: This study aimed to investigate the effect of wooden breast (WB) myopathy on chemical composition, meat quality attributes and physiochemical characteristics of intramuscular connective tissue (IMCT) of broiler pectoralis major (PM) muscle. Thirty-six ... ...

Abstract	This study aimed to investigate the effect of wooden breast (WB) myopathy on chemical composition, meat quality attributes and physiochemical characteristics of intramuscular connective tissue (IMCT) of broiler pectoralis major (PM) muscle. Thirty-six fillets were classified into varying degrees of WB condition, including normal, moderate and severe. Results show that WB myopathy altered the collagen profile in PM muscle by increasing total collagen content and decreasing collagen solubility. The composition of macromolecules in IMCT, including hydroxylysyl pyridoxine cross-linking, decorin and glycosaminoglycans, were increased with the severity of WB myopathy. Differential scanning calorimetry analysis indicated higher denaturation temperatures and lower denaturation enthalpy of IMCT for WB. Secondary structures of α-helix and β-sheet in the IMCT of WB were changed to β-turn and random coil. In addition, chemical composition and meat quality attributes showed a correlation with collagen profile and IMCT characteristics. Overall, this study emphasizes the effect of WB myopathy on IMCT and their contributions to meat quality variation.
Language	English
Publishing date	2024-02-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods13040507
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Thesis ; Online: Software Deployment Methods to Support Heterogeneous-ISA Application Migration

Xing, Tong

2020

Abstract: Edge computing is a recent computing paradigm that brings Cloud services closer to the user. The most significant feature of Edge computing is that it enables low latencies between services and users. This is because Edge nodes are physically closer to a ...

Abstract	Edge computing is a recent computing paradigm that brings Cloud services closer to the user. The most significant feature of Edge computing is that it enables low latencies between services and users. This is because Edge nodes are physically closer to a user. However, this advantage can be reduced if a user physically moves away from a specific Edge server. In order to provide a stable low latency service, services that run on Edge need to move among Edge nodes along with a user to maintain minimal physical distance. Different from the Cloud, Edge nodes usually are built with CPUs of different Instruction Set Architectures (ISA); therefore, homogeneous software migration – solution widely adopted in Cloud data-centers, cannot be used at the Edge. This thesis introduces H-Container and its integration with Docker. H-Container enables a containerized natively compiled application to migrate across Edge nodes built with different ISA CPUs. Supporting Docker, allows heterogeneous-ISA migration with Docker. H-Container is a) easily deployable – implemented in user space, without any OS or hypervisor dependency; b) highly compatible – H-Container doesn’t need the source code of the application and c) Linux friendly – H-Container targets Linux, it can migrate most Linux application binaries. Experiments demonstrate that H-Container adds no overhead on the application during the execution, while 10ms to 100ms added during the migration, and most importantly, in the experiment that is based on a real scenario, the output shows H-Container provides up to 94% increase in Redis server throughput when unlocking heterogeneity.
Keywords	Computer science
Subject code	004
Language	ENG
Publishing date	2020-01-01 00:00:01.0
Publisher	Stevens Institute of Technology
Publishing country	us
Document type	Thesis ; Online
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Article ; Online: Efficacy of creatine nitrate supplementation on redox status and mitochondrial function in

Xu, Jiawen / Xing, Tong / Li, Jiaolong / Zhang, Lin / Gao, Feng

Animal biotechnology

2024 Volume 34, Issue 8, Page(s) 3988–3999

Abstract: This study was purposed to investigate the efficacy of dietary creatine nitrate (CrN) supplementation on redox status and mitochondrial function ... ...

Abstract	This study was purposed to investigate the efficacy of dietary creatine nitrate (CrN) supplementation on redox status and mitochondrial function in
MeSH term(s)	Animals ; Pectoralis Muscles ; Creatine/pharmacology ; Creatine/metabolism ; Nitrates/pharmacology ; Nitrates/metabolism ; Chickens/metabolism ; NF-E2-Related Factor 2/metabolism ; Dietary Supplements ; Diet ; Mitochondria ; Oxidation-Reduction ; RNA, Messenger/metabolism ; Animal Feed/analysis
Chemical Substances	Creatine (MU72812GK0) ; Nitrates ; NF-E2-Related Factor 2 ; RNA, Messenger
Language	English
Publishing date	2024-01-30
Publishing country	England
Document type	Randomized Controlled Trial, Veterinary ; Journal Article
ZDB-ID	2043243-4
ISSN	1532-2378 ; 1049-5398
ISSN (online)	1532-2378
ISSN	1049-5398
DOI	10.1080/10495398.2023.2249957
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Article ; Online: BMSCs-driven graphite oxide-grafted-carbon fibers reinforced polyetheretherketone composites as functional implants:

Qin, Wen / Xing, Tong / Qin, Shengnan / Tang, Bin / Chen, Weiyi

Journal of biomaterials science. Polymer edition

2024 , Page(s) 1–16

Abstract: Mesenchymal stem cells (MSCs) are increasingly becoming a potential treatment approach for bone injuries due to the multi-lineage differentiation potential, ability to recognize damaged tissue sites and secrete bioactive factors that can enhance tissue ... ...

Abstract	Mesenchymal stem cells (MSCs) are increasingly becoming a potential treatment approach for bone injuries due to the multi-lineage differentiation potential, ability to recognize damaged tissue sites and secrete bioactive factors that can enhance tissue repair. The aim of this work was to improve osteogenesis of carbon fibers reinforced polyetheretherketone (CF/PEEK) implants through bone marrow mesenchymal stem cells (BMSCs)-based therapy. Moreover, bioactive graphene oxide (GO) was introduced into CF/PEEK by grafting GO onto CF to boost the osteogenic efficiency of BMSCs. Subsequently, CF/PEEK was implanted into the symmetrical skull defect models of SD rats. Then
Language	English
Publishing date	2024-03-17
Publishing country	England
Document type	Journal Article
ZDB-ID	1014190-x
ISSN	1568-5624 ; 1568-5616 ; 0920-5063
ISSN (online)	1568-5624 ; 1568-5616
ISSN	0920-5063
DOI	10.1080/09205063.2024.2328877
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Article ; Online: Numerical simulation of shoegear-rail coupling vibration under different initial contact forces.

Xing, Tong / Peng, Peihuo / Pan, Like / Yang, Caizhi / He, Fan

Scientific reports

2024 Volume 14, Issue 1, Page(s) 6896

Abstract: As cities have grown, conductor rail power supplies have been widely used in the field of urban rail transit. In order to improve the running performance of trains and reduce the occurrence of accidents, it is necessary to understand the vibration of ... ...

Abstract	As cities have grown, conductor rail power supplies have been widely used in the field of urban rail transit. In order to improve the running performance of trains and reduce the occurrence of accidents, it is necessary to understand the vibration of shoegear-rail system under different initial contact forces and explore the dynamic performance of shoegear-rail system. Therefore, according to the structure of shoegear-rail system, a coupling model of shoegear-rail system is established in this paper. On the basis of the model, the numerical simulation of the shoegear-rail system under different initial contact forces is carried out, and finally the vibration data of the shoegear-rail system under different initial contact forces are obtained. The results show that with the increase of initial contact force in the range of 70-160 N, the vibration amplitude of the electric shoegear and the fluctuation amplitude of the contact force increase, but the maximum absolute shear force value of the conductor rail decreases. It indicates that the lower initial contact force, the better the performance of shoegear-rail system.
Language	English
Publishing date	2024-03-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-57569-y
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Article ; Online: Decoration with electronegative 2D materials based on chemical transition layers on CFR-PEEK implants for promoting osteogenesis.

Qin, Wen / Xing, Tong / Ma, Jing / Tang, Bin / Chen, Weiyi

Journal of the mechanical behavior of biomedical materials

2024 Volume 152, Page(s) 106436

Abstract: Due to the unique lamellar structures, physicochemical and biological properties, electronegative two-dimensional (2D) materials have been explored for surface modification of carbon fibers reinforced polyetheretherketone (CFR-PEEK) composite. Deposition ...

Abstract	Due to the unique lamellar structures, physicochemical and biological properties, electronegative two-dimensional (2D) materials have been explored for surface modification of carbon fibers reinforced polyetheretherketone (CFR-PEEK) composite. Deposition of electronegative 2D materials based on a porous surface created by concentrated H
MeSH term(s)	Carbon Fiber ; Osteogenesis ; Prostheses and Implants ; Ketones ; Phosphorus ; Polyethylene Glycols ; Benzophenones ; Graphite ; Polymers
Chemical Substances	polyetheretherketone (31694-16-3) ; Carbon Fiber ; graphene oxide ; Ketones ; Phosphorus (27YLU75U4W) ; Polyethylene Glycols (3WJQ0SDW1A) ; Benzophenones ; Graphite (7782-42-5) ; Polymers
Language	English
Publishing date	2024-02-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2378381-3
ISSN	1878-0180 ; 1751-6161
ISSN (online)	1878-0180
ISSN	1751-6161
DOI	10.1016/j.jmbbm.2024.106436
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Article ; Online: Microstructure and morphology of the soldering interface of Sn–2.0Ag–1.5Zn low Ag content lead-free solder ball and different substrates

Jin Xiao / Xing Tong / Jinhui Liang / Quankun Chen / Qiming Tang

Heliyon, Vol 9, Iss 2, Pp e12952- (2023)

2023

Abstract: Eutectic Sn–Ag–Cu lead-free solder has limited applications due to cost and reliability issues. Sn–Ag–Zn solder has the advantages of low melting point, good mechanical properties and reliable welding interface. However, the research system of low silver ...

Abstract	Eutectic Sn–Ag–Cu lead-free solder has limited applications due to cost and reliability issues. Sn–Ag–Zn solder has the advantages of low melting point, good mechanical properties and reliable welding interface. However, the research system of low silver content Sn–Ag–Zn solder is incomplete. In this paper, Sn–2.0Ag–1.5Zn low silver content alloy solder is soldered to different substrates. The interfacial reaction after soldering and the microstructure and reliability under different aging treatment conditions are studied. Sn–2.0Ag–1.5Zn solder is made into solder balls by direct melting method. The solder balls are placed in a solder strength tester to be heated and welded to the substrate, and then the solder joints are placed in a heating furnace for aging treatment. The results show that the solder is soldered to the bare Cu substrate, and a dense double-layer Intermetallic Compound (IMC) structure of Cu5Zn8 and Ag3Sn is formed at the interface after aging treatment. The double-layer structure blocks each other, limiting the development of copper-tin IMCs. The solder is soldered with the Cu substrate electroplated with Ni barrier layer, and the soldering interface forms a thin layer of Ni3Sn4 metal compound. After aging for 1000 h, the thickness of Ni3Sn4 is about 1 μm, the thickness of Ni barrier layer is kept at 2–3 μm, and the barrier effect of Ni barrier layer is stable. Sn–2.0Ag–1.5Zn solder has excellent loss performance in long aging treatment. It has good heat-resistance aging treatment, good quality of solder connection, high interface reliability and less environmental pollution. The low silver content in Sn–2.0Ag–1.5Zn solder results in a significant cost reduction. Coarse IMC Ag3Sn is not easily formed. The optimized ratio of Ag and Zn in Sn–2.0Ag–1.5Zn solder improves the strength and toughness of the solder joint. The performance has been improved, and it is a very promising alloy solder.
Keywords	Sn–Ag–Zn ; Lead-free solder ; Interfacial reaction ; Low silver solder ; Solder joint ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	620
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Mechanical properties and osteogenesis of CFR-PEEK composite with interface strengthening by graphene oxide for implant application.

Qin, Wen / Xing, Tong / Tang, Bin / Chen, Weiyi

Journal of the mechanical behavior of biomedical materials

2023 Volume 148, Page(s) 106222

Abstract: In this work, 1 wt% of graphite oxide (GO) was used to strengthen the interface of carbon fibers (CF) reinforced polyetheretherketone (CFR-PEEK) composites, so as to obtain sufficiently high mechanical properties and bioactive surfaces which are two ... ...

Abstract	In this work, 1 wt% of graphite oxide (GO) was used to strengthen the interface of carbon fibers (CF) reinforced polyetheretherketone (CFR-PEEK) composites, so as to obtain sufficiently high mechanical properties and bioactive surfaces which are two fundamental requirements for orthopedic/dental implants. Concretely, aminated GO was grafted onto oxidized CF in aqueous solution in a mild and non-toxic manner, subsequently, the CF grafted by GO was used for injection molding to prepare CFR-PEEK implant. The dispersibility of CF in the composites were remarkably boosted. Mechanical tests indicated that the flexural strength, compressive strength and hardness of CFR-PEEK were increased by 51%, 46%, and 30%, respectively. Furthermore, the flexural modulus increased to 11.67 ± 0.20 GPa and the compression modulus increased to 6.12 ± 0.11 GPa, which both meet the elastic modulus of human bone (6-30 GPa). The wear resistance was slightly improved. In the in vitro cell evaluation, CFR-PEEK with interface strengthening by GO showed no cytotoxicity and exhibited significantly enhanced adhesion and proliferation of Bone marrow mesenchymal stem cells (BMSCs) on the surface. More importantly, osteogenesis-related protein expression in vitro and osteogenetic evaluation in vivo all disclosed greatly accelerated osteo-differentiation of BMSCs on the composites due to the additive effect of GO at the interface. Based on this scheme, the CFR-PEEK composites with the dual functions of mechanical enhancement and osteointegration promotion holds great potential as implants in orthopedic/dental applications.
MeSH term(s)	Humans ; Graphite ; Osteogenesis ; Polymers ; Polyethylene Glycols/pharmacology ; Ketones ; Carbon Fiber
Chemical Substances	polyetheretherketone (31694-16-3) ; graphene oxide ; Graphite (7782-42-5) ; Polymers ; Polyethylene Glycols (3WJQ0SDW1A) ; Ketones ; Carbon Fiber
Language	English
Publishing date	2023-11-04
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2378381-3
ISSN	1878-0180 ; 1751-6161
ISSN (online)	1878-0180
ISSN	1751-6161
DOI	10.1016/j.jmbbm.2023.106222
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