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Article ; Online: Tongue Edema Caused by Taking Nifedipine Controlled-Release Tablets.

Zhang, Wensheng / Xing, Weifang / Ling, Li

2024 Volume 72, Issue 1, Page(s) 195

MeSH term(s)	Humans ; Nifedipine/adverse effects ; Delayed-Action Preparations/adverse effects ; Tongue Diseases ; Tongue ; Edema/chemically induced
Chemical Substances	Nifedipine (I9ZF7L6G2L) ; Delayed-Action Preparations
Language	English
Publishing date	2024-02-29
Publishing country	India
Document type	Journal Article
ZDB-ID	415522-1
ISSN	1998-4022 ; 0028-3886
ISSN (online)	1998-4022
ISSN	0028-3886
DOI	10.4103/NI.Neurol-India-D-23-00614
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Zs.A 698: Show issues

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Article ; Online: Using stent thrombectomy to cure middle cerebral artery air embolism.

Zhang, Wensheng / Xing, Weifang / Zhu, Minzhen / He, Jinzhao

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

2024 Volume 45, Issue 6, Page(s) 2907–2911

MeSH term(s)	Humans ; Embolism, Air/therapy ; Embolism, Air/etiology ; Embolism, Air/diagnostic imaging ; Thrombectomy/methods ; Stents ; Infarction, Middle Cerebral Artery/surgery ; Infarction, Middle Cerebral Artery/diagnostic imaging ; Male ; Female ; Middle Aged ; Middle Cerebral Artery/diagnostic imaging ; Middle Cerebral Artery/surgery
Language	English
Publishing date	2024-02-06
Publishing country	Italy
Document type	Case Reports ; Letter
ZDB-ID	2016546-8
ISSN	1590-3478 ; 1590-1874
ISSN (online)	1590-3478
ISSN	1590-1874
DOI	10.1007/s10072-024-07381-3
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Zs.A 1877: Show issues

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Article ; Online: Streptococcus suis meningitis complicated with acute cerebral infarction: A case report

Xing, Weifang / Zhang, Wensheng / Zhu, Minzhen / He, Jinzhao

Heliyon. 2022 Aug., v. 8, no. 8 p.e10418-

2022

Abstract: A case of suppurative meningitis complicated with acute cerebral infarction caused by Streptococcus suis was reported to provide reference for the diagnosis and treatment of Streptococcus suis infection. The diagnosis, treatment, follow-up and ... ...

Abstract	A case of suppurative meningitis complicated with acute cerebral infarction caused by Streptococcus suis was reported to provide reference for the diagnosis and treatment of Streptococcus suis infection. The diagnosis, treatment, follow-up and epidemiological materials in the case of suppurative meningitis complicated with acute cerebral infarction caused by Streptococcus suis in Heyuan People's Hospital were reviewed, and the relevant literature was reviewed. The clinical manifestations of this case were headache and fever, which progressed rapidly. After effective anti-infection treatment, the patient improved and discharged from the hospital, but there was profound hearing impairment.
Keywords	Streptococcus suis ; case studies ; fever ; headache ; hospitals ; infarction ; meningitis ; patients ; people ; Purulent meningitis ; Acute cerebral infarction ; Hearing impairment ; Treatment
Language	English
Dates of publication	2022-08
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2022.e10418
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Article ; Online: Acute cerebral infarction of posterior circulation in a patient with vertebral artery fenestration deformity: A case report

Zhang, Wensheng / Xing, Weifang / Zhong, Guanghong / He, Jinzhao

Heliyon. 2022 Oct., v. 8, no. 10 p.e11210-

2022

Abstract: Cerebrovascular fenestration malformation is a rare congenital vascular variation. Cerebrovascular fenestration malformation rarely directly leads to cerebral infarction, and the mechanism of cerebral infarction is not clear. Cases of young patients with ...

Abstract	Cerebrovascular fenestration malformation is a rare congenital vascular variation. Cerebrovascular fenestration malformation rarely directly leads to cerebral infarction, and the mechanism of cerebral infarction is not clear. Cases of young patients with vertebral artery fenestration malformation who suffered from acute cerebral infarction of posterior circulation are rare and have not been reported widely. A 36-year-old male patient, who had been in good health and without a family history of stroke, was admitted to our hospital with a 6-h history of dizziness and unstable walking. Brain MR examination showed multiple irregular high signal lesions in the left thalamus, left occipital lobe and left cerebellum. Brain MR enhancement examination confirmed multiple cerebral infarction in left thalamus, left occipital lobe and left cerebellum. CT angiography of head and neck showed fenestration deformity of V2–V3 segment of left vertebral artery. Considering that the patient was suffering from acute cerebral infarction of posterior circulation, he was treated with antiplatelet, lipid-lowering and plaque stabilization, etc. After receiving our treatment, the patient's symptoms were relieved. At 3 and 6 months after discharge, there was no dizziness, unstable walking, no acute cerebral infarction, which meant that the patient recovered well. In the absence of traditional risk factors and other evidence of cryptogenic stroke, the cerebral infarction in the blood supply area of fenestration malformation should be considered to be related to fenestration malformation, but its pathogenesis is not clear. Antiplatelet therapy, lipid-lowering and plaque stabilization, etc. are effective in prevention of new infarction for such patients.
Keywords	abnormal development ; angiography ; blood ; case studies ; cerebellum ; head ; hospitals ; infarction ; neck ; pathogenesis ; patients ; risk ; stroke ; thalamus ; therapeutics ; Cerebrovascular fenestration malformation ; Vertebral artery fenestration malformation ; Acute cerebral infarction ; Posterior circulation ; Case report
Language	English
Dates of publication	2022-10
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2022.e11210
Database	NAL-Catalogue (AGRICOLA)

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Article: Non responsible vascular area hyperperfusion syndrome after mechanical thrombectomy for vertebral artery occlusion: A case report.

Zhang, Wensheng / Xing, Weifang / Zhong, Xiaojing / Zhu, Minzhen / He, Jinzhao

Heliyon

2023 Volume 9, Issue 6, Page(s) e16903

Abstract: Introduction: There are currently no published report: Patient concerns: A 21-year-old woman developed left vertebral artery occlusion, for which she received mechanical thrombectomy and successful recanalization of her occluded cerebral vessel. ... ...

Abstract	Introduction: There are currently no published report Patient concerns: A 21-year-old woman developed left vertebral artery occlusion, for which she received mechanical thrombectomy and successful recanalization of her occluded cerebral vessel. Subsequently, the patient became extremely agitated, with high blood pressure and headache. Diagnosis: Two hours after the operation, bedside transcranial Doppler ultrasound examination found that the cerebral blood flow velocity of the M1 segment of the right middle cerebral artery was more than twice that of the left middle cerebral artery. Combined with the symptoms, signs and examination results of the patient, hyperperfusion syndrome in the blood supply area of the right middle cerebral artery was considered. Interventions: The patient was administered sedation, and her pressure and ventricular rate were strictly controlled. She was no longer agitated, and her headache was significantly relieved at 36 hours after the operation. Outcomes: On the 5th day after the operation, the blood flow velocity of her right middle cerebral artery decreased to normal level, and the patient recovered well. Conclusion: In this case, after mechanical thrombectomy, such patients with acute posterior circulation cerebral infarction can experience hyperperfusion syndrome in the non responsible vascular area of the anterior circulation. Bedside transcranial Doppler cerebral blood flow examination can identify the hyperperfusion state of cerebral vessels in a timely manner and effectively guide treatment.
Language	English
Publishing date	2023-06-01
Publishing country	England
Document type	Case Reports
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e16903
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Article: Acute cerebral infarction of posterior circulation in a patient with vertebral artery fenestration deformity: A case report.

Zhang, Wensheng / Xing, Weifang / Zhong, Guanghong / He, Jinzhao

Heliyon

2022 Volume 8, Issue 10, Page(s) e11210

Abstract: Introduction: Cerebrovascular fenestration malformation is a rare congenital vascular variation. Cerebrovascular fenestration malformation rarely directly leads to cerebral infarction, and the mechanism of cerebral infarction is not clear. Cases of ... ...

Abstract	Introduction: Cerebrovascular fenestration malformation is a rare congenital vascular variation. Cerebrovascular fenestration malformation rarely directly leads to cerebral infarction, and the mechanism of cerebral infarction is not clear. Cases of young patients with vertebral artery fenestration malformation who suffered from acute cerebral infarction of posterior circulation are rare and have not been reported widely. Patient concerns: A 36-year-old male patient, who had been in good health and without a family history of stroke, was admitted to our hospital with a 6-h history of dizziness and unstable walking. Diagnosis: Brain MR examination showed multiple irregular high signal lesions in the left thalamus, left occipital lobe and left cerebellum. Brain MR enhancement examination confirmed multiple cerebral infarction in left thalamus, left occipital lobe and left cerebellum. CT angiography of head and neck showed fenestration deformity of V2-V3 segment of left vertebral artery. Interventions: Considering that the patient was suffering from acute cerebral infarction of posterior circulation, he was treated with antiplatelet, lipid-lowering and plaque stabilization, etc. Outcomes: After receiving our treatment, the patient's symptoms were relieved. At 3 and 6 months after discharge, there was no dizziness, unstable walking, no acute cerebral infarction, which meant that the patient recovered well. Conclusion: In the absence of traditional risk factors and other evidence of cryptogenic stroke, the cerebral infarction in the blood supply area of fenestration malformation should be considered to be related to fenestration malformation, but its pathogenesis is not clear. Antiplatelet therapy, lipid-lowering and plaque stabilization, etc. are effective in prevention of new infarction for such patients.
Language	English
Publishing date	2022-10-21
Publishing country	England
Document type	Case Reports
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2022.e11210
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Article ; Online: Correlation between ERα gene polymorphism and multiple sclerosis and neuromyelitis optica.

Xing, Weifang / Hong, Mingfan / Wei, Zhisheng / Zhang, Wensheng

Medicine

2022 Volume 101, Issue 41, Page(s) e31126

Abstract: Objective: To study the polymorphism distribution of estrogen receptor (ER) α gene and the correlation between different types of polymorphism in multiple sclerosis (MS) and neuromyelitis optica (NMO) patients.: Methods: Forty-six cases of MS and NMO ...

Abstract	Objective: To study the polymorphism distribution of estrogen receptor (ER) α gene and the correlation between different types of polymorphism in multiple sclerosis (MS) and neuromyelitis optica (NMO) patients. Methods: Forty-six cases of MS and NMO diagnosed from June 2018 to December 2019 were collected. Peripheral venous blood samples were collected. The patient's gender, age of onset, course of disease, and other clinical data were recorded. Fifty-eight healthy volunteers of the same age and sex were selected. By means of Pvu II and Xba I restriction fragment length polymorphism enzyme recognition sites of ER α gene, polymerase chain reaction-restriction fragment length polymorphism analysis was conducted. Results: There was no significant difference in the frequency distribution of ER α gene's PP, Pp, and pp genotype between MS and NMO case group and control group (P = .598). Frequency distribution of ER α gene's XX, Xx, and xx was statistically significant between MS and NMO case group and control group (P = .021). Among them, distribution of Xx and Xx gene frequency between patient group and the control group was statistically significant (P = .001, OR = 4.622, 95% CI: 1.803-11.852). There was no significant correlation between ER α genotypes and the onset age in patient group (P > .05). The difference was statistically significant in disease duration of XX and Xx genotype (P = .006). The comparison of Xx and xx genotype frequency distribution in gender exists a difference(P = .047, OR = 7.500, 95% CI: 1.023-54.996). Conclusions: Xba I gene polymorphisms in the ER α gene have correlation with MS and NMO. Xba I gene could be a risk factor of MS and NMO pathogenesis, especially the women with Xx genotype are more vulnerable. Xba I gene polymorphisms in the ER α gene may impact the disease duration of MS and NMO, or rather, the disease duration of Xx genotype persists longer than Xx genotype. Pvu II gene polymorphisms in the ER α gene has no correlation with MS and NMO.
MeSH term(s)	Female ; Humans ; Estrogen Receptor alpha/genetics ; Genotype ; Multiple Sclerosis/genetics ; Neuromyelitis Optica/genetics ; Polymorphism, Genetic
Chemical Substances	Estrogen Receptor alpha ; ESR1 protein, human
Language	English
Publishing date	2022-10-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000031126
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Ua VI Zs.171: Show issues

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Article: Streptococcus suis meningitis complicated with acute cerebral infarction: A case report.

Xing, Weifang / Zhang, Wensheng / Zhu, Minzhen / He, Jinzhao

Heliyon

2022 Volume 8, Issue 8, Page(s) e10418

Abstract	A case of suppurative meningitis complicated with acute cerebral infarction caused by Streptococcus suis was reported to provide reference for the diagnosis and treatment of Streptococcus suis infection. The diagnosis, treatment, follow-up and epidemiological materials in the case of suppurative meningitis complicated with acute cerebral infarction caused by Streptococcus suis in Heyuan People's Hospital were reviewed, and the relevant literature was reviewed. The clinical manifestations of this case were headache and fever, which progressed rapidly. After effective anti-infection treatment, the patient improved and discharged from the hospital, but there was profound hearing impairment.
Language	English
Publishing date	2022-08-28
Publishing country	England
Document type	Case Reports
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2022.e10418
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Acute pontine infarction in a patient with 8-shaped basilar artery fenestration malformation: A case report.

Zhang, WenSheng / Xing, WeiFang / Gu, HongLi / He, JinZhao

Medicine

2022 Volume 101, Issue 27, Page(s) e29445

Abstract: Introduction: Cerebrovascular fenestration malformation is a relatively rare vascular dysplasia, and an 8-shaped basilar artery fenestration malformation is even rarer. The characteristics of transcranial Doppler cerebral blood flow in cerebrovascular ... ...

Abstract	Introduction: Cerebrovascular fenestration malformation is a relatively rare vascular dysplasia, and an 8-shaped basilar artery fenestration malformation is even rarer. The characteristics of transcranial Doppler cerebral blood flow in cerebrovascular fenestration malformations have rarely been studied or reported. Patient concerns: A 58-year-old woman presented with hypertension, diabetes, with no history of smoking or drinking. The patient had no relevant family history. The patient experienced left limb weakness for 2 days, which gradually worsened. Diagnosis: Head and neck computed tomography angiography revealed an 8-shaped fenestration deformity of the lower segment of the basilar artery with multiple stenoses of the local vessels. Transcranial Doppler cerebral blood flow examination at a depth of 85 cm revealed an eddy current in the lower segment of the basilar artery. Interventions: Tirofiban was administered intravenously for 3 days and subsequently changed to oral clopidogrel antiplatelet treatment. Outcomes: The modified Rankin Scale score at 3 months after disease onset was 0, indicating that the patient recovered well after treatment. Conclusion: A basilar artery 8-shaped fenestration is extremely rare and has seldom been reported. Cerebral vascular fenestration can lead to an acute cerebral infarction and its pathogenesis may include local hemodynamic abnormalities and thrombosis. Eddy currents can be detected by transcranial Doppler cerebral blood flow examination.
MeSH term(s)	Basilar Artery/abnormalities ; Basilar Artery/diagnostic imaging ; Brain Stem Infarctions ; Cardiovascular Abnormalities ; Cerebral Arteries/diagnostic imaging ; Female ; Humans ; Middle Aged ; Tomography, X-Ray Computed ; Ultrasonography, Doppler, Transcranial
Language	English
Publishing date	2022-07-08
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000029445
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Ua VI Zs.171: Show issues

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Article ; Online: Long-segment spinal cord infarction complicated with multiple cerebral infarctions: a case report.

Xing, Weifang / Zhang, Wensheng / Ma, Guozhong / Ma, Guofen / He, Jinzhao

BMC neurology

2022 Volume 22, Issue 1, Page(s) 362

Abstract: Background: Spinal cord infarction is a rare disorder, constituting only 1% to 2% of all neurological vascular emergencies (making it less frequent than ischaemic brain injury); however, it is severe. A case of long-segment spinal cord infarction ... ...

Abstract	Background: Spinal cord infarction is a rare disorder, constituting only 1% to 2% of all neurological vascular emergencies (making it less frequent than ischaemic brain injury); however, it is severe. A case of long-segment spinal cord infarction complicated with multiple cerebral infarctions has not been reported to date. Case presentation: Here, we describe one such case: a patient with spinal cord infarction from the cervical 7 (C7) to thoracic 6 (T6) vertebrae, along with anterior spinal artery syndrome and complicated by multiple cerebral infarctions. A 65-year-old farmer experienced sudden onset of severe pain in his chest, back and upper limbs while unloading heavy objects. Subsequently, both his lower limbs became weak and hypoaesthetic, and he was unable to walk. Spinal magnetic resonance imaging (MRI) revealed equal T1 and long T2 signals centred on the anterior horn of the spinal cord. The axial slice of these signals was shaped like an owl's eye. After receiving drug treatment and active rehabilitation treatment, the patient's ability to walk was restored. Conclusions: Long-segment spinal cord infarction is rare and can be complicated with cerebral infarction. The specific aetiology is worth exploring.
MeSH term(s)	Cerebral Infarction/complications ; Cerebral Infarction/diagnostic imaging ; Cerebral Infarction/pathology ; Humans ; Infarction/complications ; Infarction/diagnostic imaging ; Intracranial Arteriosclerosis/complications ; Ischemic Attack, Transient/complications ; Magnetic Resonance Imaging/methods ; Male ; Spinal Cord/pathology ; Spinal Cord Injuries/complications ; Spinal Cord Ischemia/complications
Language	English
Publishing date	2022-09-22
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2041347-6
ISSN	1471-2377 ; 1471-2377
ISSN (online)	1471-2377
ISSN	1471-2377
DOI	10.1186/s12883-022-02888-8
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