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Article ; Online: Numerical prediction of glass molding process for 3D curved screen

Xinyu Hao / Guangdong Zhang

Heliyon, Vol 9, Iss 9, Pp e19693- (2023)

2023

Abstract: With the rapid development of consumer electronics industry, the demand for 3D curved screen in industry is also growing. At present, 3D curved screen is mass produced through glass molding process. However, due to the complex rheological properties of ... ...

Abstract	With the rapid development of consumer electronics industry, the demand for 3D curved screen in industry is also growing. At present, 3D curved screen is mass produced through glass molding process. However, due to the complex rheological properties of glass melt and the intricate deformation mechanism of glass molding process, the final geometry of the screen is difficult to predict. In this paper, the glass molding process for 3D curved screen is analyzed by finite element transient analysis. The trend of screen shape change is obtained and the final geometry of the screen is predicted. The results show that geometric fillet and rheological parameters have great influence on the flow of glass melt in glass molding process. This study is helpful for the selection of parameters of glass molding process and the design of 3D curved screen.
Keywords	Glass molding process ; Graphite mold ; 3D curved screen ; Polyflow ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	660 ; 620
Language	English
Publishing date	2023-09-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Research on Intelligent Fault Diagnosis of Rolling Bearing Based on Improved Deep Residual Network

Xinyu Hao / Yuan Zheng / Li Lu / Hong Pan

Applied Sciences, Vol 11, Iss 10889, p

2021 Volume 10889

Abstract: Rolling bearings are the most fault-prone parts in rotating machinery. In order to find faults in time and reduce losses, this paper presents an intelligent diagnosis method for rolling bearings. At present, the deep residual network (RESNET) is the most ...

Abstract	Rolling bearings are the most fault-prone parts in rotating machinery. In order to find faults in time and reduce losses, this paper presents an intelligent diagnosis method for rolling bearings. At present, the deep residual network (RESNET) is the most widely used convolutional neural network (CNN) and has become one of the hotspots in fault diagnosis. However, the fully connected layer of the deep residual network has the disadvantage of too many training parameters, which makes the model training and testing time longer. So, we proposed a new network structure which the global average pooling (GAP) technology replaces the fully connected layer part of the traditional RESNET. It effectively solves the problem of too many parameters of the traditional RESNET model, and uses data enhancement, dropout, and other deep learning training techniques to prevent the model from overfitting. Experiments show that the accuracy of fault diagnosis of the improved algorithm reaches 99.83%, training time has been shortened. Also, the whole process of rolling bearing fault detection does not need any manually extract features, and this “end-to-end” algorithm has good versatility and operability.
Keywords	fault diagnosis ; improved deep residual network ; deep learning ; GAP ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	006
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Research on Improved OEE Measurement Method Based on the Multiproduct Production System

Xiaoyan Li / Guangfu Liu / Xinyu Hao

Applied Sciences, Vol 11, Iss 2, p

2021 Volume 490

Abstract: The multiproduct production system has been applied extensively in factories worldwide due to the diverse consumption habits of consumers. However, current Overall Equipment Effectiveness (OEE) measurement methods are not suitable for it properly. With ... ...

Abstract	The multiproduct production system has been applied extensively in factories worldwide due to the diverse consumption habits of consumers. However, current Overall Equipment Effectiveness (OEE) measurement methods are not suitable for it properly. With the prevailing of multiproduct production system, it is essential to measure the effectiveness accurately in this kind of production system. In order to fill this gap, based on analyzing former OEE models, we propose the multiproduct production system effectiveness (MPSE), including the calculating steps and application framework, in this paper using the heuristic method. This MPSE is verified by a case study. The principal results show that the proposed MPSE can significantly enhance overall production effectiveness and improve the measurement of indicators in the multiproduct production system, which enriches the theory of OEE at the theoretical level and proposes a novel way to measure and improve the effectiveness of the multiproduct production system effectively at the practical level.
Keywords	overall equipment effectiveness ; multiproduct production system ; measurement method ; system effectiveness ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	670
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Traditional Chinese medicine for precancerous lesions of gastric cancer

Weichao Xu / Bolin Li / Miaochan Xu / Tianxiao Yang / Xinyu Hao

Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112542- (2022)

A review

2022

Abstract: Gastric cancer (GC) is the fifth most common type of cancer and the third leading cause of death due to cancer worldwide. The gastric mucosa often undergoes many years of precancerous lesions of gastric cancer (PLGC) stages before progressing to gastric ... ...

Abstract	Gastric cancer (GC) is the fifth most common type of cancer and the third leading cause of death due to cancer worldwide. The gastric mucosa often undergoes many years of precancerous lesions of gastric cancer (PLGC) stages before progressing to gastric malignancy. Unfortunately, there are no effective Western drugs for patients with PLGC. In recent years, traditional Chinese medicine (TCM) has been proven effective in treating PLGC. Classical TCM formulas and chemical components isolated from some Chinese herbal medicines have been administered to treat PLGC, and the main advantage is their comprehensive intervention with multiple approaches and multiple targets. In this review, we focus on recent studies using TCM treatment for PLGC, including clinical observations and experimental research, with a focus on targets and mechanisms of drugs. This review provides some ideas and a theoretical basis for applying TCM to treat PLGC and prevent GC.
Keywords	Precancerous lesions of gastric cancer ; Traditional Chinese medicine ; Pattern differentiation ; Formulas ; Pharmacological mechanism ; Therapeutics. Pharmacology ; RM1-950
Subject code	610
Language	English
Publishing date	2022-02-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Symptom clusters and characteristics of cervical cancer patients receiving concurrent chemoradiotherapy

Hao Tie / Limei Shi / Li Wang / Xinyu Hao / Hongyan Fang / Lirong Li

Heliyon, Vol 9, Iss 12, Pp e22407- (2023)

A cross-sectional study

2023

Abstract: Background: Cervical cancer patients have a high symptom burden during concurrent chemoradiotherapy (CCRT) and urgently need precise symptom management strategies. Nonetheless, the symptom profile and influencing factors are unclear. Methods: A total of ... ...

Abstract	Background: Cervical cancer patients have a high symptom burden during concurrent chemoradiotherapy (CCRT) and urgently need precise symptom management strategies. Nonetheless, the symptom profile and influencing factors are unclear. Methods: A total of 234 patients with cervical cancer who underwent CCRT in a tertiary care hospital clinical oncology center in Guangxi Zhuang Autonomous Region from March 2022 to March 2023 were included in the study. The general information questionnaire, M.D. Anderson symptom inventory, Fatigue Scale-14, Pittsburgh Sleep Quality Index, and grip strength test were used for the investigation. Symptom clusters were extracted by exploratory factor analysis, and latent profile analysis was performed using Mplus 8.0 software. Multinomial logistic regression was used to explore the factors influencing the potential categories of symptom clusters. Results: Exploratory factor analysis extracted four symptom clusters: a fatigue-related symptom cluster, a gastrointestinal-related symptom cluster, a mood-related symptom cluster, and a physical-related symptom cluster, of which the fatigue-related symptom cluster was more severe and was divided into three potential categories: low fatigue-good muscle fitness type (25.63%), general fatigue-moderate muscle fitness type (68.37%) and high fatigue-low muscle fitness type (6%). Multinomial logistic regression analysis showed that hemoglobin levels, tumor stage, absence of complications, and unemployment were factors influencing the fatigue-related symptom cluster in patients undergoing CCRT for cervical cancer. Conclusions: Cervical cancer patients experience multiple symptom clusters during CCRT. Different characteristics appeared in different clusters. Among them, fatigue-related symptom clusters were more severe and heterogeneous. In clinical practice, we should pay attention to and use high symptom feature predictors, focusing on the core symptoms that play a dominant role, achieving early identification and management, and reducing patients' ...
Keywords	Cervical cancer ; Concurrent chemotherapy ; Symptom clusters ; Influencing factors ; Latent profile analysis ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	616
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Promotion of Household Waste Utilization in China

Yanran Liu / Tingting Tian / Xinyu Hao / Qin Zhang / Chengyan Yao / Guangfu Liu

Sustainability, Vol 13, Iss 11598, p

Lessons Learnt from Three Case Studies

2021 Volume 11598

Abstract: Household waste utilization has been regarded as an important pathway to promote the circular economy paradigm and sustainable development for a long time. However, relevant enterprises are facing dilemmas in terms of the backward disposal methods for ... ...

Abstract	Household waste utilization has been regarded as an important pathway to promote the circular economy paradigm and sustainable development for a long time. However, relevant enterprises are facing dilemmas in terms of the backward disposal methods for food waste, inadequate recycling of low-value recyclable waste and the lack of leading enterprises, resulting in unsustainable expansion of the industry. To address these problems, we investigated governmental departments and 20 household waste utilization enterprises in China. From the investigation, three typical enterprises, representing the advanced technology for food waste, the recycling mode of recyclable waste and the cultivation mode of leading enterprises, were selected for case studies. The results indicate that applying the technology of bioconversion by maggots could improve the utilization of food waste and adopting the “online and offline” dual-channel mode could benefit the recycling of low-value recyclable waste. Additionally, leading enterprises can be cultivated by franchise mode, which can drive the utilization of household waste in China effectively. The findings enrich the theory of household waste utilization in terms of disposal methods, recycling modes and enterprise operation. Practically, this research should enlighten decision-makers to improve household waste utilization. Furthermore, the research results could be generalized in other countries, thereby advancing the household waste management worldwide.
Keywords	household waste utilization ; bioconversion technology ; online and offline recycling ; franchise mode ; case study ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	650
Language	English
Publishing date	2021-10-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Acupoints for Tension-Type Headache

Lingyun Lu / Qian Wen / Xinyu Hao / Qianhua Zheng / Ying Li / Ning Li

Evidence-Based Complementary and Alternative Medicine, Vol

A Literature Study Based on Data Mining Technology

2021 Volume 2021

Abstract: Objectives. This study aimed to explore the characteristics and principles of acupoints, which were applied for treating tension-type headache (TTH). Methods. Four databases were searched for the literature studies of treating TTH with acupuncture and ... ...

Abstract	Objectives. This study aimed to explore the characteristics and principles of acupoints, which were applied for treating tension-type headache (TTH). Methods. Four databases were searched for the literature studies of treating TTH with acupuncture and moxibustion up to September 1, 2020. Titles, journals, authors, key words, interventions, main acupoints, and outcomes of the included literature studies were extracted and inputted into the self-established Data Excavation Platform of Acupoint Specificity for analysis. Results. In total, 128 papers containing 137 prescriptions, 89 meridian acupoints, and 7 extraordinary acupoints of treating TTH with acupuncture and moxibustion were included. The total frequency of acupoints’ application was 763 times. Fengchi (GB20), Baihui (GV20), Taiyang (EX-HN5), Hegu (LI4), and Taichong (LR3) were used most frequently. The acupoints in Yang meridians were utilized more than those in Yin meridians (66.1% vs. 17.8%), and the acupoints in the Gallbladder Meridian of Foot Shaoyang were applied most commonly. 59.9% (457/763) of the applied acupoints were on the head, face, and neck, and 31.7% (242/763) were on the four limbs. Additionally, the proportion of specific acupoints’ application was 78.2% (597/763). Conclusions. The prescription of Fengchi (GB20), Baihui (GV20), Taiyang (EX-HN5), Hegu (LI4), and Taichong (LR3) might be relatively reasonable in clinical practices of treating TTH with acupuncture, which should be verified in further studies.
Keywords	Other systems of medicine ; RZ201-999
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Electroacupuncture on ST36 and GB39 Acupoints Inhibits Synovial Angiogenesis via Downregulating HIF-1α/VEGF Expression in a Rat Model of Adjuvant Arthritis

Jun Zhu / Chengguo Su / Yuzhou Chen / Xinyu Hao / Jianzhen Jiang

Evidence-Based Complementary and Alternative Medicine, Vol

2019 Volume 2019

Abstract: Introduction. The hypoxia inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) play a key role in synovial angiogenesis in rheumatoid arthritis (RA). Therefore, this study aimed to test the hypothesis that electroacupuncture (EA) ... ...

Abstract	Introduction. The hypoxia inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) play a key role in synovial angiogenesis in rheumatoid arthritis (RA). Therefore, this study aimed to test the hypothesis that electroacupuncture (EA) may inhibit RA synovial angiogenesis via HIF-1α/VEGF expression. Methods. Sprague-Dawley rats were randomly distributed to 4 groups: control, adjuvant arthritis (AA), AA+electroacupuncture (AA+EA), and AA+sham EA groups. AA model was induced by injection of Freund's complete adjuvant in bilateral hind footpad. 3 days after injection, EA was delivered to the acupoints Zusanli (ST 36) and Xuanzhong (GB 39) once every two days for a total of 8 times in the AA+EA group, while sham EA treatment was applied in the AA+sham EA group. The arthritis score, paw volume, and H&E staining for each animal were measured. CD34 expression in synovial tissue of ankle joint was observed by immunohistochemistry. HIF-1α and VEGF mRNA and protein levels in synovial tissue were determined by real-time quantitative PCR and Western blot, respectively. Results. Compared with rats in AA group, EA stimulation significantly decreased arthritis scores, paw volume, and pathological damage of synovial tissues. Moreover, EA markedly suppressed the synovial angiogenesis of AA rats, as evidenced by reduced CD34 positive expression. Furthermore, EA significantly reduced HIF-1α and VEGF mRNA and protein levels in synovial of AA rats. Finally, the CD34 expression in synovial tissue was positively correlated with HIF-1α and VEGF protein levels. Conclusion. EA on ST36 and GB39 acupoints can effectively inhibit synovial angiogenesis in the AA rat model via downregulating HIF-1α/VEGF expression.
Keywords	Other systems of medicine ; RZ201-999
Subject code	616 ; 630
Language	English
Publishing date	2019-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Determination of the protective effects of Hua‐Zhuo‐Jie‐Du in chronic atrophic gastritis by regulating intestinal microbiota and metabolites

Pingping Zhou / Xinyu Hao / Yu Liu / Zeqi Yang / Miaochan Xu / Shaowei Liu / Shixiong Zhang / Tianxiao Yang / Xiaomei Wang / Yangang Wang

Chinese Medicine, Vol 16, Iss 1, Pp 1-

combination of liquid chromatograph mass spectrometer metabolic profiling and 16S rRNA gene sequencing

2021 Volume 19

Abstract: Abstract Background Hua-Zhuo-Jie-Du (HZJD), a Chinese herbal prescription consisting of 11 herbs, is commonly used in China to treat chronic atrophic gastritis (CAG). We aimed to determine the effect of HZJD on the microbiome-associated metabolic changes ...

Abstract	Abstract Background Hua-Zhuo-Jie-Du (HZJD), a Chinese herbal prescription consisting of 11 herbs, is commonly used in China to treat chronic atrophic gastritis (CAG). We aimed to determine the effect of HZJD on the microbiome-associated metabolic changes in CAG rats. Methods The CAG rat models were induced by 1-methyl-3-nitro-1-nitrosoguanidine (MNNG) combined with irregular fasting and 2% sodium salicylate, which was intragastrically administrated in fasted animals for 24 weeks. The CAG rats in the Chinese medicine (CM) group were administered a daily dose of 14.81 g/kg/day HZJD, and the vitacoenzyme (V) group were administered a daily dose of 0.08 g/kg/day vitacoenzyme. All animals were treated for 10 consecutive weeks, consecutively. Hematoxylin and eosin (H&E) staining was used to assess the histopathological changes in the gastric tissues. An integrated approach based on liquid chromatograph mass spectrometer (LC-MS) metabolic profiling combined with 16S rRNA gene sequencing was carried out to assess the effects of HZJD on CAG rats. Spearman analysis was used to calculate the correlation coefficient between the different intestinal microbiota and the metabolites. Results The H&E results indicated that HZJD could improve the pathological condition of CAG rats. The LC–MS results indicated that HZJD could significantly improve 21 gastric mucosal tissue perturbed metabolites in CAG rats; the affected metabolites were found to be involved in multiple metabolic pathways, such as the central carbon metabolism in cancer. The results of 16S rRNA gene sequencing indicated that HZJD could regulate the diversity, microbial composition, and abundance of the intestinal microbiota of CAG rats. Following HZJD treatment, the relative abundance of Turicibacter was increased, and the relative abundance of Desulfococcus and Escherichia were decreased in the CM group when compared with the M group. Spearman analysis revealed that perturbed intestinal microbes had a strong correlation with differential metabolites, ...
Keywords	Hua‐Zhuo‐Jie‐Du ; Chronic atrophic gastritis ; LC–MS ; 16S rRNA gene sequencing ; Other systems of medicine ; RZ201-999
Subject code	610
Language	English
Publishing date	2021-05-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Identifying Chinese Medicine Patterns of Tension-Type Headache and Understanding Its Subgroups

Xinyu Hao / Fanrong Liang / Linpeng Wang / Kenneth Mark Greenwood / Charlie Changli Xue / Zhen Zheng / Ying Li

Evidence-Based Complementary and Alternative Medicine, Vol

2021 Volume 2021

Abstract: Tension-type headache (TTH) is common among adults. Individualized management strategies are limited due to lack of understanding of subtypes of TTH. Chinese medicine (CM) uses the pattern differentiation approach to subtype all health conditions. There ... ...

Abstract	Tension-type headache (TTH) is common among adults. Individualized management strategies are limited due to lack of understanding of subtypes of TTH. Chinese medicine (CM) uses the pattern differentiation approach to subtype all health conditions. There is, however, a lack of evidence-based information on CM patterns of TTH. This study aimed to identity common CM patterns of TTH. TTH sufferers were invited for a survey, consisting of a validated Chinese Medicine Headache Questionnaire (CMHQ), Migraine Disability Assessment Test, and Perceived Stress Scale. The CMHQ consisted of information about headache, aggravating and relieving factors, and accompanying symptoms. Principal component analysis was used for factor extraction and TwoStep cluster analyses for identifying clusters. ANOVA was used to compare cluster groups with disability and stress. In total, 170 eligible participants took part in the survey. The commonest headache features were continuous pain (64%); fixed location (74%); aggravated by overwork (74%), stress (74%), or mental strain (70%); and relieved by sleeping (78%). The commonest nonpain symptoms were fatigue (71%) and neck stiffness (70%). Four clusters, differing in their key signs and symptoms, could be assigned to three different CM patterns including ascendant hyperactivity of liver yang (cluster 1), dual qi and blood deficiency (cluster 2), liver depression forming fire (cluster 3), and an unlabelled group (cluster 4). Additionally, over 75% participants in clusters 1 and 2 have episodic TTH, over one-third participants in cluster 3 have chronic TTH, and a majority of participants in cluster 4 have infrequent TTH. The three patterns identified also differed in levels of disability and some elements of coping as measured with PSS. The three CM patterns identified are common clinical presentations of TTH. The new information will contribute to further understanding of the subtypes of TTH and guide the development of targeted intervention combinations for clinical practice and research.
Keywords	Other systems of medicine ; RZ201-999
Subject code	150
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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