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  1. Article ; Online: Research on the Structure and Characteristics of Adolescent Physical Health Policy in China Based on Policy Text Tool

    Yuting Hu / Xinyu Ma

    Sustainability, Vol 15, Iss 8657, p

    2023  Volume 8657

    Abstract: The health of young people is an important guarantee for national development and rejuvenation. In the past five years, the Chinese government has issued a series of policies on adolescent physical health, which have effectively promoted the development ... ...

    Abstract The health of young people is an important guarantee for national development and rejuvenation. In the past five years, the Chinese government has issued a series of policies on adolescent physical health, which have effectively promoted the development of adolescent health. In this study, we collected national policies on adolescent physical health from 2016 to 2022 as research objects. Based on the theory of policy instruments, this paper constructs a three-dimensional framework of “policy instrument-adolescent physical health contents-adolescent physical health policy target audience”. The study found that the use of adolescent health policy tools in China is uneven, as most policies are biased towards supply-side policies. The lack of targeted protection policies for adolescents’ physical health is due to the lagging development of physical standards, lack of monitoring technology, and complex governance policies. Policy use by governments, schools, and communities is widely distributed, resulting in a lag in the overall effectiveness of adolescent physical health policies. To this end, we put forward the following suggestions: First, the use of policy instruments should be optimized. Secondly, on the basis of adolescent health monitoring, the physical health standards suitable for national conditions should be formulated. Moreover, we should improve the governance model and guarantee a system to fill the policy blank of the implementation of adolescent physical health. Finally, we should promote the coordinated development of mental health with “moral” as the core.
    Keywords China ; adolescent ; physical health ; policy ; policy tools ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 796 ; 360
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Mineralization and Fixed Stable Carbon Isotopic Characteristics of Organic Carbon in Cotton Fields with Different Continuous Cropping Years

    Xinyu Ma / Lu Gong / Yuxin Yang / Zhaolong Ding / Xinzhu Li

    Agronomy, Vol 13, Iss 804, p

    2023  Volume 804

    Abstract: The oasis carbon pool in arid zones is an important part of the global carbon pool. There is a soil organic carbon (SOC)–soil–CO 2 –soil inorganic carbon (SIC) balanced system in the soil, which facilitates the change from soil organic carbon to soil ... ...

    Abstract The oasis carbon pool in arid zones is an important part of the global carbon pool. There is a soil organic carbon (SOC)–soil–CO 2 –soil inorganic carbon (SIC) balanced system in the soil, which facilitates the change from soil organic carbon to soil inorganic carbon. A small change in the soil carbon pool can affect the overall global carbon balance, thus affecting the conversion of soil carbon in terrestrial ecosystems. In this study, the change from soil organic carbon to soil inorganic carbon (SIC) was obtained by measuring the δ 13 C values of SIC and CO 2 in combination with stable carbon isotope techniques in cotton fields with different continuous cropping years, in the Alar Reclamation Area. Additionally, this was combined with redundancy analysis to reveal the effects of different physicochemical factors on the change amount. The results showed that the soil inorganic carbon content along the soil profile showed an increasing trend, while the soil organic carbon content was the opposite; the δ 13 C of SIC in the 0–20 and 60–80 cm soil layers were the highest in the 10a continuous cotton field soil, which were −22.24 and −21.86‰, respectively, and significantly different to other types ( p < 0.05). The fixed carbon values in the barren, 5a, 10a, 20a, and 30a continuous cotton fields were 0.53, 0.17, 0.11, 0.13 and 0.33 g·kg −1 , respectively; the corresponding amounts of CO 2 fixed from soil respiration were 0.33, 0.11, 0.08, 0.05, and 0.25 g·kg −1

    the amounts of CO 2 from the atmosphere were 0.20, 0.06, 0.03, 0.02, and 0.09 g·kg −1

    and the oxidative decomposition of CO 2 by SOC were 0.17, 0.06, 0.04, 0.26, and 0.12 g·kg −1 , respectively, indicating that the contribution of SOC was more in the barren field and 30a cotton field. Comparing the sources of fixed CO 2 , we found that the amount of fixed soil from barren fields and 30a was high from atmospheric CO 2 , while the contribution of SOC was low. Furthermore, the amount of fixed CO 2 of 20a from SOC was high, and the atmospheric contribution ...
    Keywords organic carbon ; inorganic carbon ; stable carbon isotope technology ; oasis cotton field ; Agriculture ; S
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Efflux pump inhibitor chlorpromazine effectively increases the susceptibility of

    Bing, Cao / Mengjuan, An / Xinyu, Ma / Chixin, Zhu / Xinyao, Tan / Yan, Sun / Zhi, Li

    Future microbiology

    2024  

    Abstract: Aim: ...

    Abstract Aim:
    Language English
    Publishing date 2024-04-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2254620-0
    ISSN 1746-0921 ; 1746-0913
    ISSN (online) 1746-0921
    ISSN 1746-0913
    DOI 10.2217/fmb-2023-0272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A biochemical reconstitution approach to identify autophagy receptors for aggrephagy in mammalian cells

    Xinyu Ma / Wenhao Zhang / Haiteng Deng / Min Zhang / Liang Ge

    STAR Protocols, Vol 3, Iss 3, Pp 101662- (2022)

    2022  

    Abstract: Summary: Aggrephagy is a major way to clear protein aggregates. Here, we describe a pipeline of experiments to find autophagy receptors for aggrephagy. Steps include an in vitro reconstitution to recapitulate autophagosome recognizing aggregates and ... ...

    Abstract Summary: Aggrephagy is a major way to clear protein aggregates. Here, we describe a pipeline of experiments to find autophagy receptors for aggrephagy. Steps include an in vitro reconstitution to recapitulate autophagosome recognizing aggregates and receptor identification steps based on flow cytometry and mass spectrometry. We also describe functional validation steps based on immunofluorescence and immunoblot. The protocol provides a practical way to identify aggrephagy receptors.For complete details on the use and execution of this protocol, please refer to Ma et al. (2022). : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.
    Keywords Cell biology ; Flow cytometry/Mass cytometry ; Protein biochemistry ; Science (General) ; Q1-390
    Language English
    Publishing date 2022-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Drug-Drug Interaction Predictions via Knowledge Graph and Text Embedding

    Meng Wang / Haofen Wang / Xing Liu / Xinyu Ma / Beilun Wang

    JMIR Medical Informatics, Vol 9, Iss 6, p e

    Instrument Validation Study

    2021  Volume 28277

    Abstract: BackgroundMinimizing adverse reactions caused by drug-drug interactions (DDIs) has always been a prominent research topic in clinical pharmacology. Detecting all possible interactions through clinical studies before a drug is released to the market is a ... ...

    Abstract BackgroundMinimizing adverse reactions caused by drug-drug interactions (DDIs) has always been a prominent research topic in clinical pharmacology. Detecting all possible interactions through clinical studies before a drug is released to the market is a demanding task. The power of big data is opening up new approaches to discovering various DDIs. However, these data contain a huge amount of noise and provide knowledge bases that are far from being complete or used with reliability. Most existing studies focus on predicting binary DDIs between drug pairs and ignore other interactions. ObjectiveLeveraging both drug knowledge graphs and biomedical text is a promising pathway for rich and comprehensive DDI prediction, but it is not without issues. Our proposed model seeks to address the following challenges: data noise and incompleteness, data sparsity, and computational complexity. MethodsWe propose a novel framework, Predicting Rich DDI, to predict DDIs. The framework uses graph embedding to overcome data incompleteness and sparsity issues to make multiple DDI label predictions. First, a large-scale drug knowledge graph is generated from different sources. The knowledge graph is then embedded with comprehensive biomedical text into a common low-dimensional space. Finally, the learned embeddings are used to efficiently compute rich DDI information through a link prediction process. ResultsTo validate the effectiveness of the proposed framework, extensive experiments were conducted on real-world data sets. The results demonstrate that our model outperforms several state-of-the-art baseline methods in terms of capability and accuracy. ConclusionsWe propose a novel framework, Predicting Rich DDI, to predict DDIs. Using rich DDI information, it can competently predict multiple labels for a pair of drugs across numerous domains, ranging from pharmacological mechanisms to side effects. To the best of our knowledge, this framework is the first to provide a joint translation-based embedding model that learns DDIs by ...
    Keywords Computer applications to medicine. Medical informatics ; R858-859.7
    Subject code 006
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher JMIR Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Research on 3D Improved Extended Finite Element Method for Electric Field of Liquid Nitrogen with Bubbles

    Nana Duan / Xinyu Ma / Shaocong Lu / Weijie Xu / Shuhong Wang

    Applied Sciences, Vol 11, Iss 4839, p

    2021  Volume 4839

    Abstract: In this paper, the improved extended finite element method (XFEM) for analyzing the three-dimensional (3D) electric field is presented. The interface between two media is described by using a four-dimensional (4D) level set function. For elements with ... ...

    Abstract In this paper, the improved extended finite element method (XFEM) for analyzing the three-dimensional (3D) electric field is presented. The interface between two media is described by using a four-dimensional (4D) level set function. For elements with multiple interfaces, the local level set method is used to improve the accuracy. By using weak discontinuous enrichment function and moving level set function, the interpolation function is modified. The new interpolation function makes it unnecessary to repeat the mesh generation when a moving interface occurs. The cost of calculation is greatly reduced. The reliability of 3D improved XFEM in the electric field is verified through numerical calculation examples of single bubble, multi-bubbles, and moving deformed bubble in liquid nitrogen.
    Keywords XFEM ; 3D electric field ; 4D level set function ; enrichment function ; moving deformed bubble ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 600
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Experimental Study on Permeability and Stress Sensitivity of Different Lithological Surrounding Rock Combinations

    Runsheng Lv / Jiao Xue / Zhen Zhang / Xinyu Ma / Bing Li / Yuchen Zhu / Yunbo Li

    Frontiers in Earth Science, Vol

    2022  Volume 9

    Abstract: The different lithological combinations of the surrounding rock of coal seams play a key role in controlling the enrichment and migration of coalbed methane (gas), and their permeability and stress sensitivity have important theoretical guiding ... ...

    Abstract The different lithological combinations of the surrounding rock of coal seams play a key role in controlling the enrichment and migration of coalbed methane (gas), and their permeability and stress sensitivity have important theoretical guiding significance for the regional election and evaluation of coalbed methane development. In this paper, the HB-2 type coal rock sample pore permeability adsorption simulation measurement device is used to carry out the sensitivity experiment of the permeability of different surrounding rock combinations on the effective stress of the No. 3 coal seam roof in the Daping coal mine area, Luan, Shanxi. The sensitivity coefficient of permeability to effective stress, the maximum damage rate of permeability, and other parameters are defined to characterize the response mode of permeability to effective stress and the dynamic change rule of permeability, and reveal the control mechanism of effective stress on permeability change of different surrounding rock combinations. The results show that the permeability of the roof of No. 3 coal seam is highly sensitive to the effective stress, and the permeability of different surrounding rock combinations decreases with the increase of the effective stress, and there is a strong negative exponential correlation between the permeability and the effective stress; the stress sensitivity coefficients of different surrounding rock combinations under unloading stress are higher than those under loading; the permeability changes of specimens with different combinations of surrounding rock under the same experimental conditions are varied and the differentiation phenomenon is significant; the permeability is affected by lithology, pore fissure degree, and different combinations of surrounding rock, among which different combinations of surrounding rock are the main controlling factors for the dynamic change of permeability.
    Keywords surrounding rocks ; combinations ; stress sensitivity ; different lithology ; permeability ; Science ; Q
    Subject code 550
    Language English
    Publishing date 2022-02-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: DB-DCAFN

    Jingkun Wang / Xinyu Ma / Long Cao / Yilin Leng / Zeyi Li / Zihan Cheng / Yuzhu Cao / Xiaoping Huang / Jian Zheng

    Visual Computing for Industry, Biomedicine, and Art, Vol 6, Iss 1, Pp 1-

    dual-branch deformable cross-attention fusion network for bacterial segmentation

    2023  Volume 16

    Abstract: Abstract Sputum smear tests are critical for the diagnosis of respiratory diseases. Automatic segmentation of bacteria from sputum smear images is important for improving diagnostic efficiency. However, this remains a challenging task owing to the high ... ...

    Abstract Abstract Sputum smear tests are critical for the diagnosis of respiratory diseases. Automatic segmentation of bacteria from sputum smear images is important for improving diagnostic efficiency. However, this remains a challenging task owing to the high interclass similarity among different categories of bacteria and the low contrast of the bacterial edges. To explore more levels of global pattern features to promote the distinguishing ability of bacterial categories and maintain sufficient local fine-grained features to ensure accurate localization of ambiguous bacteria simultaneously, we propose a novel dual-branch deformable cross-attention fusion network (DB-DCAFN) for accurate bacterial segmentation. Specifically, we first designed a dual-branch encoder consisting of multiple convolution and transformer blocks in parallel to simultaneously extract multilevel local and global features. We then designed a sparse and deformable cross-attention module to capture the semantic dependencies between local and global features, which can bridge the semantic gap and fuse features effectively. Furthermore, we designed a feature assignment fusion module to enhance meaningful features using an adaptive feature weighting strategy to obtain more accurate segmentation. We conducted extensive experiments to evaluate the effectiveness of DB-DCAFN on a clinical dataset comprising three bacterial categories: Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa. The experimental results demonstrate that the proposed DB-DCAFN outperforms other state-of-the-art methods and is effective at segmenting bacteria from sputum smear images.
    Keywords Bacterial segmentation ; Dual-branch parallel encoder ; Deformable cross-attention module ; Feature assignment fusion module ; Drawing. Design. Illustration ; NC1-1940 ; Computer applications to medicine. Medical informatics ; R858-859.7 ; Computer software ; QA76.75-76.765
    Subject code 006
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher SpringerOpen
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Teaching Philosophy and Its Embodiment

    Xinyu Ma

    Asian Social Science, Vol 4, Iss

    2009  Volume 12

    Abstract: In order to encourage students to think actively and practice hand-on activities in class, this article reviews some common sense and needed technique in teaching and proposes some teaching philosophy. It also demonstrates observed differences between ... ...

    Abstract In order to encourage students to think actively and practice hand-on activities in class, this article reviews some common sense and needed technique in teaching and proposes some teaching philosophy. It also demonstrates observed differences between Chinese students and western students. Its goal is to encourage all of the teachers to revisit the reasons why and the purposes behind daily actions in teaching, so as to improve the effect of classroom teaching and to impel teaching reform in China.
    Keywords Social sciences (General) ; H1-99 ; Social Sciences ; H
    Language English
    Publishing date 2009-02-01T00:00:00Z
    Publisher Canadian Center of Science and Education
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Research on Extended Finite Element Method for Axisymmetric Electrostatic Field Based on Liquid Nitrogen with Bubbles

    Nana Duan / Shaocong Lu / Xinyu Ma / Weijie Xu / Fuquan Jin / Shuhong Wang

    Applied Sciences, Vol 11, Iss 5214, p

    2021  Volume 5214

    Abstract: In this paper, the extended finite element method (XFEM) is first applied to account for the weak discontinuity of the axisymmetric electrostatic field. Firstly, the interface between two materials in an element is described by the level set method. The ... ...

    Abstract In this paper, the extended finite element method (XFEM) is first applied to account for the weak discontinuity of the axisymmetric electrostatic field. Firstly, the interface between two materials in an element is described by the level set method. The enrichment function is used to modify the shape function of enrichment elements. Secondly, to illustrate the feature of the enrichment function, the distribution diagrams of enrichment functions in sub-elements are drawn. The 3D field can be simplified to an axisymmetric field, which can reduce the difficulty of calculation. Finally, models with bubbles in liquid nitrogen in the axisymmetric field are used to prove the reliability of XFEM. Compared with the conventional finite element method (CFEM), XFEM costs lower computing resources with almost the same computational accuracy.
    Keywords extended finite element method ; axisymmetric field ; enrichment function ; liquid nitrogen ; bubbles ; electric field ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 600
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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