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  1. Article ; Online: Letter to the Editor: High platelet-to-lymphocyte ratio predicts poor survival of elderly patients with hip fracture.

    Xiong, Liang

    International orthopaedics

    2021  Volume 45, Issue 6, Page(s) 1655–1656

    MeSH term(s) Aged ; Blood Platelets ; Hip Fractures/surgery ; Humans ; Lymphocytes
    Language English
    Publishing date 2021-03-16
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 80384-4
    ISSN 1432-5195 ; 0341-2695
    ISSN (online) 1432-5195
    ISSN 0341-2695
    DOI 10.1007/s00264-021-05002-8
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1324: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Research Progress on Sesquiterpenoids of

    Cui, Ting / Li, Bo-Yu / Liu, Fei / Xiong, Liang

    Biomolecules

    2024  Volume 14, Issue 4

    Abstract: ... Curcumae ... ...

    Abstract Curcumae Rhizoma
    MeSH term(s) Curcuma/chemistry ; Sesquiterpenes/chemistry ; Sesquiterpenes/pharmacology ; Sesquiterpenes/isolation & purification ; Rhizome/chemistry ; Humans ; Animals ; Plant Extracts/chemistry ; Plant Extracts/pharmacology
    Chemical Substances Sesquiterpenes ; Plant Extracts
    Language English
    Publishing date 2024-03-23
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2701262-1
    ISSN 2218-273X ; 2218-273X
    ISSN (online) 2218-273X
    ISSN 2218-273X
    DOI 10.3390/biom14040387
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Acute kidney injury interacts with VKORC1 genotype on initiative warfarin dose among heart surgery recipients: a real-world research.

    Xiong, Liang / Yu, Feng / Ge, Weihong / Xu, Hang

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 21750

    Abstract: Patients who receive heart valve surgery need anticoagulation prophylaxis to reduce the risk of thrombosis. Warfarin often is a choice but its dosage varies due to gene and clinical factors. We aim to study, among them, if there is an interaction between ...

    Abstract Patients who receive heart valve surgery need anticoagulation prophylaxis to reduce the risk of thrombosis. Warfarin often is a choice but its dosage varies due to gene and clinical factors. We aim to study, among them, if there is an interaction between acute kidney injury and two gene polymorphisms from this study. We extracted data of heart valve surgery recipients from the electronic health record (EHR) system of a medical center. The primary outcome is about the average daily dose of warfarin, measured as an additive interaction effect (INTadd) between acute kidney injury (AKI) and warfarin-related gene polymorphisms. The confounders, including age, sex, body surface area (BSA), comorbidities (i.e., atrial fibrillation [AF], hypertension [HTN], congestive heart failure [CHF]), serum albumin level, warfarin-relevant gene polymorphism (i.e., CYP2C9, VKORC1), prosthetic valve type (i.e., metal, bio), and warfarin history were controlled via a multivariate-linear regression model. The study included 200 patients, among whom 108 (54.00%) are female. Further, the mean age is 54.45 years, 31 (15.50%) have CHF, and 40 (20.00%) patients were prescribed concomitant amiodarone, which potentially overlays with the warfarin prophylaxis period. During the follow-up, AKI occurred in 30 (15.00%) patients. VKORC1 mutation (1639G>A) occurred in 25 (12.50%) patients and CYPC29 *2 or *3 mutations presented in 20 patients (10.00%). We found a significant additive interaction effect between AKI and VKORC1 (- 1.17, 95% CI - 1.82 to - 0.53, p = 0.0004). This result suggests it is probable that there is an interaction between acute kidney injury and the VKORC1 polymorphism for the warfarin dose during the initial period of anticoagulation prophylaxis.
    MeSH term(s) Humans ; Female ; Middle Aged ; Male ; Warfarin ; Aryl Hydrocarbon Hydroxylases/genetics ; Vitamin K Epoxide Reductases/genetics ; Anticoagulants ; Genotype ; Cardiac Surgical Procedures/adverse effects ; Acute Kidney Injury/genetics ; Acute Kidney Injury/drug therapy ; Cytochrome P-450 CYP2C9/genetics ; Dose-Response Relationship, Drug
    Chemical Substances Warfarin (5Q7ZVV76EI) ; Aryl Hydrocarbon Hydroxylases (EC 1.14.14.1) ; Vitamin K Epoxide Reductases (EC 1.17.4.4) ; Anticoagulants ; Cytochrome P-450 CYP2C9 (EC 1.14.13.-) ; VKORC1 protein, human (EC 1.17.4.4)
    Language English
    Publishing date 2023-12-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-46895-2
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  4. Article: [Non-local attention and multi-task learning based lung segmentation in chest X-ray].

    Xiong, Liang / Qin, Xiaolin / Liu, Xin

    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi

    2023  Volume 40, Issue 5, Page(s) 912–919

    Abstract: Precise segmentation of lung field is a crucial step in chest radiographic computer-aided diagnosis system. With the development of deep learning, fully convolutional network based models for lung field segmentation have achieved great effect but are ... ...

    Abstract Precise segmentation of lung field is a crucial step in chest radiographic computer-aided diagnosis system. With the development of deep learning, fully convolutional network based models for lung field segmentation have achieved great effect but are poor at accurate identification of the boundary and preserving lung field consistency. To solve this problem, this paper proposed a lung segmentation algorithm based on non-local attention and multi-task learning. Firstly, an encoder-decoder convolutional network based on residual connection was used to extract multi-scale context and predict the boundary of lung. Secondly, a non-local attention mechanism to capture the long-range dependencies between pixels in the boundary regions and global context was proposed to enrich feature of inconsistent region. Thirdly, a multi-task learning to predict lung field based on the enriched feature was conducted. Finally, experiments to evaluate this algorithm were performed on JSRT and Montgomery dataset. The maximum improvement of Dice coefficient and accuracy were 1.99% and 2.27%, respectively, comparing with other representative algorithms. Results show that by enhancing the attention of boundary, this algorithm can improve the accuracy and reduce false segmentation.
    MeSH term(s) X-Rays ; Algorithms ; Diagnosis, Computer-Assisted ; Thorax/diagnostic imaging ; Lung/diagnostic imaging ; Image Processing, Computer-Assisted
    Language Chinese
    Publishing date 2023-09-14
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2576847-5
    ISSN 1001-5515
    ISSN 1001-5515
    DOI 10.7507/1001-5515.202211079
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6887: Show issues Location:
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  5. Article ; Online: Effect of the Cross-Section of a Porous Burner on the Combustion Stability Limit of Premixed Oxy-Methane Flames

    Mingjian Liao / Zhu He / Xiong Liang / Yawei Li / Xuecheng Xu

    ACS Omega, Vol 8, Iss 50, Pp 48258-

    2023  Volume 48268

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Comparison of Percutaneous Transforaminal Endoscopic Decompression and Full Endoscopic Lamina Fenestration Decompression in the Treatment of Degenerative Lumbar Spinal Stenosis with Unilateral Radicular Pain: A Retrospective Study.

    Xiong, Liang / Liu, Fengping / Zhao, Hongwei / Luo, Mingyi / Lu, Bin / Deng, Yuxiang / Zhou, Zhenyu

    Annali italiani di chirurgia

    2024  Volume 95, Issue 1, Page(s) 30–41

    Abstract: Background: Endoscopic decompression of the spinal canal is an emerging procedure for the treatment of degenerative lumbar spinal stenosis, but there are few reports of comparative studies of endoscopic techniques for transforaminal and non- ... ...

    Abstract Background: Endoscopic decompression of the spinal canal is an emerging procedure for the treatment of degenerative lumbar spinal stenosis, but there are few reports of comparative studies of endoscopic techniques for transforaminal and non-transforaminal approaches.
    Objective: To compare the clinical application of percutaneous transforaminal endoscopic decompression (PTED) and full endoscopic lamina fenestration decompression (Endo-LOVE) for treating degenerative lumbar spinal stenosis with unilateral radicular pain.
    Methods: A total of 58 patients with degenerative lumbar spinal stenosis (DLSS) with unilateral radicular pain in the lower extremities who underwent endoscopic decompression treatment from June 2020 to December 2021 were retrospectively identified and divided into two groups (PTED vs Endo-LOVE). The two groups' perioperative data were analyzed according to surgical modalities. The Visual Analogue Score (VAS) for pain, Oswestry Disability Index (ODI), modified MacNab criteria, and dural sac cross-sectional area (DSCSA) were used to assess the post-operative outcomes of the two groups.
    Results: All 58 patients completed the operation and received more than 12 months of follow-up. There was no significant difference in the operation time, number of intraoperative fluoroscopies, intraoperative bleeding, or postoperative hospitalization time between the two groups (p > 0.05); VAS scores and ODIs of the two groups at all postoperative time points were significantly lower than before the operation (p < 0.05), and there was no significant difference in the comparison of the clinical efficacy between the two groups (p > 0.05); the DSCSA of the two groups at the last postoperative follow-up was significantly larger than before the operation (p < 0.05), and there was no significant difference in the improvement of DSCSA between them (p > 0.05).
    Conclusions: Both procedures are safe and effective in the treatment of DLSS with unilateral lower extremity radicular pain, and we should be specific about the choice of spinal stenosis treatment.
    MeSH term(s) Humans ; Retrospective Studies ; Spinal Stenosis/complications ; Spinal Stenosis/surgery ; Decompression, Surgical/methods ; Lumbar Vertebrae/surgery ; Endoscopy ; Treatment Outcome ; Pain/surgery
    Language English
    Publishing date 2024-02-26
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 418927-9
    ISSN 2239-253X ; 0003-469X
    ISSN (online) 2239-253X
    ISSN 0003-469X
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 50: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  7. Article: Is it reasonable to shorten the length of cemented stems? A finite element analysis and biomechanical experiment.

    Li, Junyan / Xiong, Liang / Lei, Chao / Wu, Xinyu / Mao, Xinzhan

    Frontiers in bioengineering and biotechnology

    2023  Volume 11, Page(s) 1289985

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-11-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1289985
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  8. Article ; Online: Novel Indane Derivatives with Antioxidant Activity from the Roots of

    Meng, Chun-Wang / Zhao, Hao-Yu / Zhu, Huan / Peng, Cheng / Zhou, Qin-Mei / Xiong, Liang

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 3

    Abstract: Four novel indane derivatives, anisotindans A-D ( ...

    Abstract Four novel indane derivatives, anisotindans A-D (
    MeSH term(s) Antioxidants/pharmacology ; Antioxidants/chemistry ; Molecular Structure
    Chemical Substances Antioxidants ; 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid (28752-68-3)
    Language English
    Publishing date 2023-02-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28031493
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    Zs.MO 81: Show issues

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  9. Article: Dietary Betaine Supplementation Enhances Colonic Barrier Function through the Nrf2/Keap1 and TLR4-NF-κB/MAPK Signaling Pathways and Alters Colonic Microbiota in Bama Mini-Pigs.

    Xiong, Liang / Wang, Kai / Song, Mingtong / Azad, Md Abul Kalam / Zhu, Qian / Kong, Xiangfeng

    Antioxidants (Basel, Switzerland)

    2023  Volume 12, Issue 11

    Abstract: This study evaluated the effects of betaine supplementation in sows and/or their offspring's diets on the redox status, immune and inflammatory levels, colonic barrier function, and colonic microbial community of offspring piglets. Thirty-six Bama mini- ... ...

    Abstract This study evaluated the effects of betaine supplementation in sows and/or their offspring's diets on the redox status, immune and inflammatory levels, colonic barrier function, and colonic microbial community of offspring piglets. Thirty-six Bama mini-sows on day 3 of gestation and their weaned offspring piglets (28 d of age) were randomly allocated to the following treatments: (1) sows and their weaned offspring fed the basal diet (control group, Con group); (2) sows fed the basal diet with 3.50 kg/t betaine, and their weaned offspring fed the basal diet (sows betaine group, SB group); (3) sows fed the basal diet with 3.50 kg/t betaine, and their weaned offspring fed the basal diet with 2.50 kg/t betaine (sow-offspring betaine group, S-OB group). Six offspring piglets from each group were selected to collect plasma and colon samples on d 30, 60, and 90 after weaning. Compared with the Con group, the plasma levels of IgA, IgM, GSH-Px, and SOD during d 30-90 after weaning, IFN-α, T-AOC, and GSH on d 30 and 60 after weaning were increased, while MDA during d 30-90 after weaning was decreased in the SB and S-OB groups (
    Language English
    Publishing date 2023-10-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704216-9
    ISSN 2076-3921
    ISSN 2076-3921
    DOI 10.3390/antiox12111926
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  10. Article ; Online: Association of

    Zeng, Yali / Wen, Shuang / Huan, Lijun / Xiong, Liang / Zhong, Botao / Wang, Pengyun

    PeerJ

    2023  Volume 11, Page(s) e15226

    Abstract: Background: Apolipoprotein E (: Methods: A total of 1,738 participants, including 743 patients with T2DM and 995 controls without T2DM, were enrolled from central China, and : Results: The ... ...

    Abstract Background: Apolipoprotein E (
    Methods: A total of 1,738 participants, including 743 patients with T2DM and 995 controls without T2DM, were enrolled from central China, and
    Results: The genotype
    MeSH term(s) Humans ; Apolipoproteins E/genetics ; Cholesterol, LDL ; Diabetes Mellitus, Type 2/epidemiology ; East Asian People ; Lipids ; Polymorphism, Genetic
    Chemical Substances Apolipoproteins E ; Cholesterol, LDL ; Lipids ; ApoE protein, human
    Language English
    Publishing date 2023-04-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2703241-3
    ISSN 2167-8359 ; 2167-8359
    ISSN (online) 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.15226
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