LIVIVO - Search results -

Search results

Result 1 - 10 of total 227

Search options

Article ; Online: Amino acids in piglet diarrhea: Effects, mechanisms and insights.

Zhou, Xihong / Liang, Jing / Xiong, Xia / Yin, Yulong

Animal nutrition (Zhongguo xu mu shou yi xue hui)

2023 Volume 16, Page(s) 267–274

Abstract: Piglet diarrhea is among one of the most serious health problems faced by the pig industry, resulting in significant economic losses. Diarrheal disease in piglets has a multifactorial etiology that is affected by physiology, environment, and management ... ...

Abstract	Piglet diarrhea is among one of the most serious health problems faced by the pig industry, resulting in significant economic losses. Diarrheal disease in piglets has a multifactorial etiology that is affected by physiology, environment, and management strategy. Diarrhea is the most apparent symptom of intestinal dysfunction. As a key class of essential nutrients in the piglet diet, amino acids confer a variety of beneficial effects on piglets in addition to being used as a substrate for protein synthesis, including maintaining appropriate intestinal integrity, permeability and epithelial renewal, and alleviating morphological damage and inflammatory and oxidative stress. Thus, provision of appropriate levels of amino acids could alleviate piglet diarrhea. Most amino acid effects are mediated by metabolites, gut microbes, and related signaling pathways. In this review, we summarize the current understanding of dietary amino acid effects on gut health and diarrhea incidence in piglets, and reveal the mechanisms involved. We also provide ideas for using amino acid blends and emphasize the importance of amino acid balance in the diet to prevent diarrhea in piglets.
Language	English
Publishing date	2023-10-24
Publishing country	China
Document type	Journal Article ; Review
ISSN	2405-6383
ISSN (online)	2405-6383
DOI	10.1016/j.aninu.2023.07.009
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Tryptophan, an important link in regulating the complex network of skin immunology response in atopic dermatitis.

Huang, Yaxin / Chen, Lingna / Liu, Fuming / Xiong, Xia / Ouyang, Yongliang / Deng, Yongqiong

Frontiers in immunology

2024 Volume 14, Page(s) 1300378

Abstract: Atopic dermatitis (AD) is a common chronic relapsing inflammatory skin disease, of which the pathogenesis is a complex interplay between genetics and environment. Although the exact mechanisms of the disease pathogenesis remain unclear, the immune ... ...

Abstract	Atopic dermatitis (AD) is a common chronic relapsing inflammatory skin disease, of which the pathogenesis is a complex interplay between genetics and environment. Although the exact mechanisms of the disease pathogenesis remain unclear, the immune dysregulation primarily involving the Th2 inflammatory pathway and accompanied with an imbalance of multiple immune cells is considered as one of the critical etiologies of AD. Tryptophan metabolism has long been firmly established as a key regulator of immune cells and then affect the occurrence and development of many immune and inflammatory diseases. But the relationship between tryptophan metabolism and the pathogenesis of AD has not been profoundly discussed throughout the literatures. Therefore, this review is conducted to discuss the relationship between tryptophan metabolism and the complex network of skin inflammatory response in AD, which is important to elucidate its complex pathophysiological mechanisms, and then lead to the development of new therapeutic strategies and drugs for the treatment of this frequently relapsing disease.
MeSH term(s)	Humans ; Dermatitis, Atopic ; Tryptophan/metabolism ; Skin
Chemical Substances	Tryptophan (8DUH1N11BX)
Language	English
Publishing date	2024-01-22
Publishing country	Switzerland
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2023.1300378
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Lactobacillus rhamnosus

Huang, Yukun / Huang, Yaxin / Xia, Dengmei / Liu, Lu / Xiong, Xia / Ouyang, Yongliang / Deng, Yongqiong

Frontiers in immunology

2024 Volume 14, Page(s) 1293048

Abstract: Background: The depletion of beneficial bacteria in the gut has been found in patients with acne vulgaris, and in previous studies, the supplement of : Methods: To mimic the human intestinal environment, a pseudo-germ-free rat model was used, and ... ...

Abstract	Background: The depletion of beneficial bacteria in the gut has been found in patients with acne vulgaris, and in previous studies, the supplement of Methods: To mimic the human intestinal environment, a pseudo-germ-free rat model was used, and then gut microbiota from healthy individuals and acne patients were transplanted into rats. The effects of Results: L. rhamnosus Conclusion: Our study demonstrated that
MeSH term(s)	Adult ; Humans ; Animals ; Rats ; Rats, Sprague-Dawley ; Gastrointestinal Microbiome ; Lacticaseibacillus rhamnosus ; RNA, Ribosomal, 16S ; Tryptophan ; Indoles ; Acne Vulgaris/therapy
Chemical Substances	RNA, Ribosomal, 16S ; Tryptophan (8DUH1N11BX) ; Indoles
Language	English
Publishing date	2024-01-05
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2023.1293048
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Signet-Ring Cutaneous Metastasis Presenting with Huge Bunches of Grapes.

Hao, Zhenyu / Deng, Yongqiong / He, Yuanmin / Xiong, Xia

Clinical, cosmetic and investigational dermatology

2022 Volume 15, Page(s) 1997–2001

Abstract: Signet-ring cell (SRC) is a histologic type in which cells show unique features under the microscope. We mainly found signet-ring cells (SRCs) in gastrointestinal and breast tumors. Cutaneous metastasis from internal carcinomas was an uncommon ... ...

Abstract	Signet-ring cell (SRC) is a histologic type in which cells show unique features under the microscope. We mainly found signet-ring cells (SRCs) in gastrointestinal and breast tumors. Cutaneous metastasis from internal carcinomas was an uncommon presentation. The cases of signet-ring cell carcinoma (SRCC) metastasis to the skin were rarely reported. Cutaneous metastasis indicated a poor prognosis for a patient. Here, we report a female who had huge grape-like nodules arising from gastrointestinal SRCC in her trunk and thigh.
Language	English
Publishing date	2022-09-21
Publishing country	New Zealand
Document type	Case Reports
ZDB-ID	2494852-4
ISSN	1178-7015
ISSN	1178-7015
DOI	10.2147/CCID.S378478
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: A Traditional Chinese Herb Citri Reticulatae Pericarpium Induced Melanonychia.

Jiang, Shiyu / Xu, Jixiang / Xiong, Xia / Deng, Yongqiong

Clinical, cosmetic and investigational dermatology

2022 Volume 15, Page(s) 1–4

Abstract: The common causes for melanonychia include melanoma, repetitive trauma, underlying systemic diseases, onychomycosis, pseudomonas infection and drugs. Drug-induced melanonychia usually affects numerous nails and appears as light brown to black ... ...

Abstract	The common causes for melanonychia include melanoma, repetitive trauma, underlying systemic diseases, onychomycosis, pseudomonas infection and drugs. Drug-induced melanonychia usually affects numerous nails and appears as light brown to black pigmentation on the deck or nail bed with longitudinal, transverse or diffuse distribution. In previous cases, a number of chemotherapeutic agents such as azathioprine, bleomycin sulfate, cyclophosphamide, hydroxyurea and methotrexate were usually linked to melanonychia. Citri reticulatae pericarpium (CRP) is a traditional Chinese herb which is widely used in many foods and health care products in China. Up till now, there were no adverse reactions of CRP reported throughout the literature. Herein, we firstly reported a case of melanonychia in a 67-year-old man caused by CRP for external use.
Language	English
Publishing date	2022-01-04
Publishing country	New Zealand
Document type	Case Reports
ZDB-ID	2494852-4
ISSN	1178-7015
ISSN	1178-7015
DOI	10.2147/CCID.S346829
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: MUC21 controls melanoma progression via regulating SLITRK5 and hedgehog signaling pathway.

Liu, Xueping / Xiao, Yajun / Xiong, Xia / Qi, Xiaoyi

Cell biology international

2022 Volume 46, Issue 9, Page(s) 1458–1467

Abstract: Mucins are heavily glycosylated proteins secreted by various cell types, to protect the epithelial surface of the gastrointestinal tract from damage. Currently, increasing studies provided evidence to suggest that mucins play an essential role in ... ...

Abstract	Mucins are heavily glycosylated proteins secreted by various cell types, to protect the epithelial surface of the gastrointestinal tract from damage. Currently, increasing studies provided evidence to suggest that mucins play an essential role in regulating tumor progression. However, the role of mucins and the underpinning mechanism of how mucins drive melanoma progression remains elusive. In this study, we first demonstrated that mucin 21 (MUC21) expression was significantly upregulated in metastatic melanoma tissues, and a higher MUC21 expression resulted in poor overall survival in melanoma patients by The Cancer Genome Atlas database analysis. In vitro, MUC21 overexpression markedly promoted proliferative properties and aggressive behavior of melanoma cell A375 and A875, as assessed by Cell Counting Kit-8 and transwell assay. In mechanism, we proved that MUC21 suppressed expression of SLITRK5, an integral membrane protein, leading to activation of prosurvival hedgehog pathway and sustained melanoma development. More importantly, we found that combination of hedgehog pathway inhibitor cyclopamine and chemotherapy revealed an improved anticancer effect in MUC21 overexpression xenograft model. Altogether, our study described a novel role of MUC21 in regulating tumor progression, which offers a promising target for melanoma diagnosis and therapy.
MeSH term(s)	Cell Line, Tumor ; Cell Proliferation ; Glycosylation ; Hedgehog Proteins/genetics ; Hedgehog Proteins/metabolism ; Humans ; Melanoma/pathology ; Membrane Glycoproteins/genetics ; Membrane Glycoproteins/metabolism ; Mucins/genetics ; Mucins/metabolism ; Signal Transduction
Chemical Substances	Hedgehog Proteins ; MUC21 protein, human ; Membrane Glycoproteins ; Mucins
Language	English
Publishing date	2022-05-17
Publishing country	England
Document type	Journal Article
ZDB-ID	1143453-3
ISSN	1095-8355 ; 1065-6995
ISSN (online)	1095-8355
ISSN	1065-6995
DOI	10.1002/cbin.11817
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1451: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Removal of manganese from aqueous solution by a permeable reactive barrier loaded with hydroxyapatite-coated quartz sand

Lu, Qiyuan / Zhang, Weimin / Xiong, Xia / Guo, Yadan / Huang, Dandan / Liu, Haiyan

Environ Sci Pollut Res. 2023 Feb., v. 30, no. 7 p.19393-19409

2023

Abstract: Hydroxyapatite-coated quartz sands were synthesized by the sol–gel method and employed as a permeable reactive barrier (PRB) medium for the manganese contaminated aqueous solution treatment. The effects of composite particle size, initial concentration ... ...

Abstract	Hydroxyapatite-coated quartz sands were synthesized by the sol–gel method and employed as a permeable reactive barrier (PRB) medium for the manganese contaminated aqueous solution treatment. The effects of composite particle size, initial concentration of manganese, and hydraulic load on the manganese removal in aqueous solution were investigated by column test. The Thomas and Yoon-Nelson dynamic models were used to reproduce the Mn(II) adsorption behavior observed in these column experiments. The scanning electron microscope (SEM) coupled with energy dispersive spectrometer (EDS), X-ray diffractometer (XRD), and X-ray photoelectron spectroscopy (XPS) were employed to investigate the Mn(II) removal mechanism. Results showed that the initial concentration of manganese had the greatest influence on Mn(II) removal when the initial concentration of manganese is 3 mg/L, the particle size is 0.15 ~ 0.3 mm, the hydraulic load is 5.5 m³/m²·d, and the adsorption capacity of the composites reached the maximum of 1.10 mg/g. The Thomas model fitted the breakthrough curves better. The maximum adsorption capacity of Mn(II) is 0.7546 mg/g. The adsorption mechanisms are mainly ion exchange and dissolution–precipitation. The results indicate that the hydroxyapatite-coated quartz sands could be an effective PRB media for the manganese-contaminated water treatment.
Keywords	X-ray diffraction ; X-ray photoelectron spectroscopy ; adsorption ; aqueous solutions ; energy-dispersive X-ray analysis ; ion exchange ; manganese ; models ; particle size ; quartz ; sand ; sol-gel processing ; water treatment
Language	English
Dates of publication	2023-02
Size	p. 19393-19409.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-23528-1
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 5915: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Identification of integrase inhibitor-related drug resistance mutations in newly diagnosed ART-naïve HIV patients

Wang, Nan / Xiong, Xia / Liu, Zhiqi / Zhang, Ruixian / Luo, Sha / Zhang, Hongying / Wu, Xuping

Microbial Pathogenesis. 2023 Aug., v. 181 p.106217-

2023

Abstract: In China, the recommended treatment regimens for HIV-infected individuals were tenofovir in combination with lamivudine or emtricitabine as NRTIs, efavirenz or rilpivirine as NNRTIs, lopinavir/ritonavir as protease inhibitors, and raltegravir or ... ...

Abstract	In China, the recommended treatment regimens for HIV-infected individuals were tenofovir in combination with lamivudine or emtricitabine as NRTIs, efavirenz or rilpivirine as NNRTIs, lopinavir/ritonavir as protease inhibitors, and raltegravir or dolutegravir as INSTIs. The development of drug resistance increases the risk of viral rebound, opportunistic infections, and ultimately treatment failure such that the early detection of resistance is ideal. This study was developed to explore primary drug resistance characteristics and genotypic distributions in newly diagnosed antiretroviral therapy (ART)-naïve HIV-1 patients in Nanjing with the goal of establishing a basis for their individualized treatment in the clinic. Samples of serum were collected from newly diagnosed ART-naïve HIV patients from the Second Hospital of Nanjing between May 2021 and May 2022. The HIV-1 integrase (IN), protease (PR), and reverse transcriptase (RT) gene coding sequences were amplified from these samples, sequenced, and assessed for drug resistance-related mutations. Major integrase resistance-related mutations were detected in 4/360 amplified samples, with 5 other patient samples exhibiting accessory resistance mutations. The overall prevalence of PR and RT inhibitor-related transmitted drug resistance mutations (TDRMs) in this patient population was 16.99% (61/359). The most common mutations were non-nucleoside reverse transcriptase inhibitor-related mutations (51/359; 14.21%), followed by those associated with nucleoside reverse transcriptase inhibitors (7/359; 1.95%) and protease inhibitors (7/359; 1.95%). Dual-resistant strains were also observed in a subset of patients. In summary, this study is the first to have surveyed the prevalence of integrase inhibitor resistance-related mutations and other drug resistance-related mutations among newly diagnosed ART-naïve HIV-positive patients in Nanjing, China. These results highlight the need for further molecular surveillance-based monitoring of the HIV epidemic in Nanjing.
Keywords	HIV infections ; RNA-directed DNA polymerase ; antiretroviral agents ; blood serum ; drug development ; drug resistance ; genes ; hospitals ; integrase inhibitors ; integrases ; lamivudine ; pathogenesis ; patients ; proteinases ; risk ; therapeutics ; China ; HIV-1 ; Drug resistance mutations ; Integrase strand transfer inhibitors ; Genotype
Language	English
Dates of publication	2023-08
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	632772-2
ISSN	1096-1208 ; 0882-4010
ISSN (online)	1096-1208
ISSN	0882-4010
DOI	10.1016/j.micpath.2023.106217
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.A 2136: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Retraction Notice to: miR-140-3p Inhibits Cutaneous Melanoma Progression by Disrupting AKT/p70S6K and JNK Pathways through ABHD2.

He, Yuanmin / Yang, Yan / Liao, Yongmei / Xu, Jixiang / Liu, Li / Li, Changqiang / Xiong, Xia

Molecular therapy oncolytics

2023 Volume 31, Page(s) 100742

Abstract: This retracts the article DOI: 10.1016/j.omto.2020.03.009.]. ...

Abstract	[This retracts the article DOI: 10.1016/j.omto.2020.03.009.].
Language	English
Publishing date	2023-11-03
Publishing country	United States
Document type	Retraction of Publication
ISSN	2372-7705
ISSN	2372-7705
DOI	10.1016/j.omto.2023.100742
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Exploring the Mechanisms and Molecular Targets of Taohong Siwu Decoction for the Treatment of Androgenetic Alopecia Based on Network Analysis and Molecular Docking.

Tan, Xiaoqi / He, Yuxin / Ou, Yongliang / Xiong, Xia / Deng, Yongqiong

Clinical, cosmetic and investigational dermatology

2022 Volume 15, Page(s) 1225–1236

Abstract: Purpose: Taohong Siwu decoction (THSWD) is traditionally used to treat androgenic alopecia (AGA) in clinical practice of traditional Chinese medicine. This study used a network pharmacology approach to elucidate the molecular mechanism governing the ... ...

Abstract	Purpose: Taohong Siwu decoction (THSWD) is traditionally used to treat androgenic alopecia (AGA) in clinical practice of traditional Chinese medicine. This study used a network pharmacology approach to elucidate the molecular mechanism governing the effect of THSWD on AGA. Materials and methods: The major active components and their corresponding targets of THSWD were screened. AGA-related targets were obtained by analyzing the differentially expressed genes between AGA patients and healthy individuals. The protein-protein interaction networks of putative targets of THSWD and AGA-related targets were visualized and merged to identify the candidate targets for THSWD against AGA. Gene ontology (GO) biological processes and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis for core targets were performed. Finally, the key effective components and core targets screened were verified by molecular docking. Results: In this study, 69 compounds and 202 compound targets of THSWD, as well as 1158 disease targets, were screened. Forty-five interactive targets were identified for constructing the "ingredient-targets" network. The functional annotations of target genes were found to be related to oxidative stress, reactive oxygen species, and hydrogen peroxide. Pathways involved in the treatment of AGA included apoptosis and PI3K-AKT signaling pathways. The luteolin, quercetin, kaempferol, baicalein, and beta-carotene were identified as the vital active compounds, and AKT1, TP53, JUN, CASP3 and MYC were considered as the core targets. Assessment of molecular docking revealed that these active compounds and targets had good-binding interactions. Conclusion: The results indicated that the effects of THSWD against AGA may be related to anti-inflammation and anti-oxidation properties of the compounds through the specific biological processes and the related pathways.
Language	English
Publishing date	2022-07-01
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2494852-4
ISSN	1178-7015
ISSN	1178-7015
DOI	10.2147/CCID.S361820
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito