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Book ; Online: The Molecular Mechanisms of Antibiotic Resistance in Aquatic Pathogens

Lin, Xiangmin / Poeta, Patrícia / Peng, Bo / Xiong, Xiao-Peng

2020

Keywords	Science: general issues ; Infectious & contagious diseases ; aquatic pathogens ; antibiotic resistance ; mechanisms ; multidrug resistance ; prevention strategies
Size	1 electronic resource (118 pages)
Publisher	Frontiers Media SA
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021231552
ISBN	9782889661695 ; 2889661695
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Preparation of a composite coating film via vapor induced phase separation for air purification and real-time bacteria photocatalytic inactivation.

Zhong, Chengtang / Xiong, Xiaopeng

Progress in organic coatings

2021 Volume 161, Page(s) 106486

Abstract: Infectious diseases resulted from transmitting of bacteria or virus like COVID-19 via air-borne droplets have brought severe threat to human beings worldwide. Cutting the spreading paths to obtain clean air is one of the promising strategies to prevent ... ...

Abstract	Infectious diseases resulted from transmitting of bacteria or virus like COVID-19 via air-borne droplets have brought severe threat to human beings worldwide. Cutting the spreading paths to obtain clean air is one of the promising strategies to prevent people from such dangerous diseases. In this work, we have employed a strategy of spray coating in combination with vapor induced phase separation to prepare a composite coating film to fulfill that purpose. A stable mixture suspension containing micelles of block copolymer of poly(styrene-
Language	English
Publishing date	2021-09-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2015714-9
ISSN	0300-9440
ISSN	0300-9440
DOI	10.1016/j.porgcoat.2021.106486
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The circular RNA circATP8B(2) regulates ROS production and antiviral immunity in Drosophila.

Liang, Weihong / Liu, Wei / Xiong, Xiao-Peng / Li, Jennifer W / Li, Jian-Liang / Perera, Ranjan J / Zhou, Rui

Cell reports

2024 Volume 43, Issue 4, Page(s) 113973

Abstract: We identified and validated a collection of circular RNAs (circRNAs) in Drosophila melanogaster. We show that depletion of the pro-viral circRNA circATP8B(2), but not its linear siblings, compromises viral infection both in cultured Drosophila cells and ... ...

Abstract	We identified and validated a collection of circular RNAs (circRNAs) in Drosophila melanogaster. We show that depletion of the pro-viral circRNA circATP8B(2), but not its linear siblings, compromises viral infection both in cultured Drosophila cells and in vivo. In addition, circATP8B(2) is enriched in the fly gut, and gut-specific depletion of circATP8B(2) attenuates viral replication in an oral infection model. Furthermore, circATP8B(2) depletion results in increased levels of reactive oxygen species (ROS) and enhanced expression of dual oxidase (Duox), which produces ROS. Genetic and pharmacological manipulations of circATP8B(2)-depleted flies that reduce ROS levels rescue the viral replication defects elicited by circATP8B(2) depletion. Mechanistically, circATP8B(2) associates with Duox, and circATP8B(2)-Duox interaction is crucial for circATP8B(2)-mediated modulation of Duox activity. In addition, Gαq, a G protein subunit required for optimal Duox activity, acts downstream of circATP8B(2). We conclude that circATP8B(2) regulates antiviral defense by modulating Duox expression and Duox-dependent ROS production.
MeSH term(s)	Animals ; Reactive Oxygen Species/metabolism ; RNA, Circular/genetics ; RNA, Circular/metabolism ; Drosophila melanogaster/immunology ; Drosophila melanogaster/genetics ; Drosophila melanogaster/metabolism ; Drosophila Proteins/metabolism ; Drosophila Proteins/genetics ; Virus Replication ; RNA/metabolism ; RNA/genetics ; NADPH Oxidases/metabolism ; NADPH Oxidases/genetics ; Dual Oxidases/metabolism ; Dual Oxidases/genetics
Chemical Substances	Reactive Oxygen Species ; RNA, Circular ; Drosophila Proteins ; RNA (63231-63-0) ; NADPH Oxidases (EC 1.6.3.-) ; Dual Oxidases (EC 1.11.1.-)
Language	English
Publishing date	2024-03-19
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2649101-1
ISSN	2211-1247 ; 2211-1247
ISSN (online)	2211-1247
ISSN	2211-1247
DOI	10.1016/j.celrep.2024.113973
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Application Effectiveness of Segment IV Portal Vein Reconstruction for Early Postoperative Liver Function Recovery in Split Liver Transplantation.

Muhammad, Imran / Rehman, Faisal U L / Wang, Feng / Xiong, Xiaopeng / Lianghao, Zhang / Jinzhen, Cai

Transplant international : official journal of the European Society for Organ Transplantation

2023 Volume 36, Page(s) 10808

Abstract: The objective of this study was to investigate the significance of portal vein reconstruction in segment IV of the liver on early postoperative liver function recovery in split liver transplantation. The clinical data of patients of right trilobe split ... ...

Abstract	The objective of this study was to investigate the significance of portal vein reconstruction in segment IV of the liver on early postoperative liver function recovery in split liver transplantation. The clinical data of patients of right trilobe split liver transplantation in our center were analyzed and divided into two groups, including a group without portal vein reconstruction and a group with portal vein reconstruction. Clinical data of alanine aminotransferase (ALT), aspartate transaminase (AST), albumin (ALB), creatinine (Cr), total bilirubin (TB), alkaline phosphatase (ALP), gamma-glutamyl Transferase (GGT), lactic acid (Lac), and international normalized ratio (INR) levels were analyzed. The technique of segment IV portal vein reconstruction is beneficial to the early postoperative recovery of liver function. Statistically, there was no significant effect of portal vein reconstruction in the IV segment of the liver on the recovery of liver function within 1 week after split liver transplantation. There was no significant difference in survival rate between the control group and reconstruction group over the 6 months follow-up period after surgery.
MeSH term(s)	Humans ; Liver Transplantation/methods ; Portal Vein/surgery ; Recovery of Function ; Liver/surgery ; Vascular Surgical Procedures ; Living Donors
Language	English
Publishing date	2023-04-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	639435-8
ISSN	1432-2277 ; 0934-0874
ISSN (online)	1432-2277
ISSN	0934-0874
DOI	10.3389/ti.2023.10808
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Article ; Online: Impaired geriatric 8 score is associated with worse survival after radical intensity modulated radiation therapy in elderly patients with nasopharyngeal carcinoma.

Liao, Zhaohui / Zhao, Li / Xiong, Xiaopeng / Lu, Tianzhu / Zhong, Fangyan / Gong, Xiaochang / Li, Jingao

Acta oto-laryngologica

2023 Volume 143, Issue 4, Page(s) 334–339

Abstract: Background: Geriatric 8 score (G8) was an independent prognostic factor for survival and toxicities in various malignancies, but it has never been tested in nasopharyngeal carcinoma (NPC).: Objectives: To evaluate the value of G8 in predicting ... ...

Abstract	Background: Geriatric 8 score (G8) was an independent prognostic factor for survival and toxicities in various malignancies, but it has never been tested in nasopharyngeal carcinoma (NPC). Objectives: To evaluate the value of G8 in predicting survival in elderly patients with NPC. Material and methods: Patients with NPC aged ≥70 who received intensity-modulated radiation therapy were recruited into this study. The overall survival (OS), progression-free survival (PFS), locoregional recurrence rate (LRR), and distant metastasis rate (DMR) between the patients with G8 > 14 and G8 ≤ 14 were calculated using the Kaplan-Meier method and compared with the Log-rank test. Cox proportional hazards model was applied to perform univariate and multivariate analysis. Results: G8 ≤ 14 had significantly reduced OS ( Conclusions and significance: G8 is useful in predicting the OS in elderly patients with NPC. Further prospective study stratified by G8 is needed to explore the value of CT in elderly patients with NPC.
MeSH term(s)	Aged ; Humans ; Nasopharyngeal Carcinoma ; Carcinoma ; Prospective Studies ; Nasopharyngeal Neoplasms/pathology ; Retrospective Studies ; Neoplasm Recurrence, Local/pathology ; Radiotherapy, Intensity-Modulated/adverse effects ; Prognosis ; Disease-Free Survival ; Neoplasm Staging
Language	English
Publishing date	2023-03-30
Publishing country	England
Document type	Journal Article
ISSN	1651-2251
ISSN (online)	1651-2251
DOI	10.1080/00016489.2023.2190769
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Article ; Online: Investigation of air flow and pollutant dispersion in street canyon

Liu Hongjiao / Xiong Xiaopeng / Jin Mei / Shi Ling

E3S Web of Conferences, Vol 136, p

2019 Volume 05002

Abstract: With the rapid development of the city, more and more attention has been paid to the air quality of street canyon.We numerically investigate the air flow and pollutant dispersion in the street canyon with different window opening percentage, different ... ...

Abstract	With the rapid development of the city, more and more attention has been paid to the air quality of street canyon.We numerically investigate the air flow and pollutant dispersion in the street canyon with different window opening percentage, different wind speed and roof shapes. The results show that the window opening area leads to a significant improvement of removing pollutant out of street canyon, especially for pollutants distributed on upsides of leeward and windward walls.With increasing window opening percentage, the pollutant concentration K distributed on downsides of leeward and windward walls gradually decreases. With the growth in wind speed, the pollutant concentration K also drops. The slanted roof shape may be a better choice to improve the efficiency of pollutant removal.
Keywords	Environmental sciences ; GE1-350
Language	English
Publishing date	2019-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A circular RNA Edis-Relish-castor axis regulates neuronal development in Drosophila.

Liu, Wei / Liang, Weihong / Xiong, Xiao-Peng / Li, Jian-Liang / Zhou, Rui

PLoS genetics

2022 Volume 18, Issue 10, Page(s) e1010433

Abstract: Circular RNAs (circRNAs) are a new group of noncoding/regulatory RNAs that are particularly abundant in the nervous system, however, their physiological functions are underexplored. Here we report that the brain-enriched circular RNA Edis (Ect4-derived ... ...

Abstract	Circular RNAs (circRNAs) are a new group of noncoding/regulatory RNAs that are particularly abundant in the nervous system, however, their physiological functions are underexplored. Here we report that the brain-enriched circular RNA Edis (Ect4-derived immune suppressor) plays an essential role in neuronal development in Drosophila. We show that depletion of Edis in vivo causes defects in axonal projection patterns of mushroom body (MB) neurons in the brain, as well as impaired locomotor activity and shortened lifespan of adult flies. In addition, we find that the castor gene, which encodes a transcription factor involved in neurodevelopment, is upregulated in Edis knockdown neurons. Notably, castor overexpression phenocopies Edis knockdown, and reducing castor levels suppresses the neurodevelopmental phenotypes in Edis-depleted neurons. Furthermore, chromatin immunoprecipitation analysis reveals that the transcription factor Relish, which plays a key role in regulating innate immunity signaling, occupies a pair of sites at the castor promoter, and that both sites are required for optimal castor gene activation by either immune challenge or Edis depletion. Lastly, Relish mutation and/or depletion can rescue both the castor gene hyperactivation phenotype and neuronal defects in Edis knockdown animals. We conclude that the circular RNA Edis acts through Relish and castor to regulate neuronal development.
MeSH term(s)	Animals ; Drosophila/genetics ; RNA, Circular/genetics ; Drosophila Proteins/genetics ; Transcription Factors/genetics ; Mushroom Bodies ; Drosophila melanogaster/physiology
Chemical Substances	RNA, Circular ; Drosophila Proteins ; Transcription Factors
Language	English
Publishing date	2022-10-27
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
ZDB-ID	2186725-2
ISSN	1553-7404 ; 1553-7390
ISSN (online)	1553-7404
ISSN	1553-7390
DOI	10.1371/journal.pgen.1010433
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Robust but On-Demand Detachable Wet Tissue Adhesive Hydrogel Enhanced with Modified Tannic Acid.

Wang, Xinyue / Huang, Hongjian / Xu, Renfeng / Fang, Yan / Weng, Yunxiang / Wang, Zhengchao / Xiong, Xiaopeng / Liu, Haiqing

ACS applied materials & interfaces

2023 Volume 15, Issue 39, Page(s) 45676–45688

Abstract: Adhesives with robust but readily detachable wet tissue adhesion are of great significance for wound closure. Polyelectrolyte complex adhesive (PECA) is an important wet tissue adhesive. However, its relatively weak cohesive and adhesive strength cannot ... ...

Abstract	Adhesives with robust but readily detachable wet tissue adhesion are of great significance for wound closure. Polyelectrolyte complex adhesive (PECA) is an important wet tissue adhesive. However, its relatively weak cohesive and adhesive strength cannot satisfy clinical applications. Herein, modified tannic acid (mTA) with a catechol group, a long alkyl hydrophobic chain, and a phenyl group was prepared first, and then, it was mixed with acrylic acid (AA) and polyethylenimine (PEI), followed by UV photopolymerization to make a wet tissue adhesive hydrogel with tough cohesion and adhesion strength. The hydrogel has a strong wet tissue interfacial toughness of ∼1552 J/m
MeSH term(s)	Humans ; Animals ; Swine ; Tissue Adhesives/pharmacology ; Hydrogels ; Heart ; Kidney ; Tannins ; Adhesives
Chemical Substances	Tissue Adhesives ; Hydrogels ; Tannic Acid ; Tannins ; Adhesives
Language	English
Publishing date	2023-09-21
Publishing country	United States
Document type	Journal Article
ISSN	1944-8252
ISSN (online)	1944-8252
DOI	10.1021/acsami.3c10140
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Hydrogel-Mediated Mineralization Generates Oriented Crystalline Films Comprising Granular-Rhombohedral Heterogeneous Structures

Feng, Yu-xuan / Wen, Yue-E / Liu, Xiang-Dong / Xiong, Xiaopeng / Jiang, Yuan

Langmuir. 2021 June 16, v. 37, no. 25

2021

Abstract: Gel-mediated crystallization is a common system to produce self-organized materials, which is fundamental to the development of bottom-up approaches to functional complex materials. Mineralization in hydrogel matrices nevertheless remains empirical in ... ...

Abstract	Gel-mediated crystallization is a common system to produce self-organized materials, which is fundamental to the development of bottom-up approaches to functional complex materials. Mineralization in hydrogel matrices nevertheless remains empirical in the generation of crystallization products with tailored heterogeneous structures. We demonstrate that the employment of the hydrogels with proper cationic diffusivity can trigger the consecutive growth of oriented, granular-rhombohedral heterogeneous structures. The controllable morphogenesis leads to continuous calcitic CaCO₃ films comprising spatial heterogeneity, where epitaxial match assumedly favors the successive deposition of both granular and rhombohedral layers. The scenario of consecutive growth is disclosed, where the thickness of the granular layers can become a valuable indicator to reflect the retardancy degree of crystallization. The evaluation of the physicochemical properties of the hydrogels finally establishes a direct correlation between the cationic diffusivity of the hydrogels and the appearance of the heterogeneous structures. The current work therefore sheds light on the implementation of rational morphogenetic approaches to crystalline materials with tailored complex architectures.
Keywords	crystallization ; diffusivity ; hydrogels ; mineralization ; morphogenesis ; spatial variation
Language	English
Dates of publication	2021-0616
Size	p. 7741-7750.
Publishing place	American Chemical Society
Document type	Article
ZDB-ID	2005937-1
ISSN	1520-5827 ; 0743-7463
ISSN (online)	1520-5827
ISSN	0743-7463
DOI	10.1021/acs.langmuir.1c00863
Database	NAL-Catalogue (AGRICOLA)

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Article: Modification of microcrystalline cellulose with acrylamide under microwave irradiation and its application as flocculant

Yu, Xiuling / Bai, Changzhuang / Huang, Xuejiao / Xiong, Xiaopeng

Environmental science and pollution research international. 2019 Nov., v. 26, no. 32

2019

Abstract: Grafting polyacrylamide (PAM) chains onto microparticles may combine the advantages of the flocculation property of the former and the fast sedimentation of the later to realize better flocculation performance. In this work, inexpensive microcrystalline ... ...

Abstract	Grafting polyacrylamide (PAM) chains onto microparticles may combine the advantages of the flocculation property of the former and the fast sedimentation of the later to realize better flocculation performance. In this work, inexpensive microcrystalline cellulose (MCC) microparticles, and monomer of acrylamide (AM) were mixed, and then irradiated under microwave. The obtained material was characterized by Fourier transform infrared spectroscopy and X-ray diffraction, and the results demonstrated successful modification of MCC with AM on the particle surface. The modification procedure has been carefully investigated to obtain an optimum preparation condition. Kaolin suspension was selected as a model to evaluate the flocculation properties of the obtained AM-MCC. Our results indicate that the AM-MCC with the highest grafting ratio of 95.5% exhibits the best flocculation performance, which is even better than that of PAM, and the turbidity can be decreased to 1.4% of the naked kaolin suspension within 2.5 min. Therefore, this work provides a low cost strategy to prepare biodegradable AM-MCC, which may have promising potential application in the water treatment and other fields.
Keywords	acrylamides ; biodegradability ; cellulose ; flocculants ; flocculation ; Fourier transform infrared spectroscopy ; irradiation ; kaolin ; microparticles ; microwave radiation ; models ; polyacrylamide ; turbidity ; water treatment ; X-ray diffraction
Language	English
Dates of publication	2019-11
Size	p. 32859-32865.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-019-06317-1
Database	NAL-Catalogue (AGRICOLA)

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