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  1. Article: Spatial Patterns and Determinants of Inter-county Migration in California: A Multilevel Gravity Model Approach.

    Xu, Anqi

    Population research and policy review

    2023  Volume 42, Issue 3, Page(s) 40

    Abstract: Understanding migration patterns and their determinants is crucial for population estimation and resource allocation for policymakers. Utilizing residential mobility data collected by the Department of Motor Vehicles, this present study provides a ... ...

    Abstract Understanding migration patterns and their determinants is crucial for population estimation and resource allocation for policymakers. Utilizing residential mobility data collected by the Department of Motor Vehicles, this present study provides a spatiotemporal analysis of inter-county migration in California for the period 2014-2021. We use multilevel gravity models to address the hierarchical nature of migration data and the effects of migration flows sharing common origins, destinations, and regions, providing a substantively complete examination of push and pull forces affecting migration. Our findings show that populous counties in Southern California and the San Francisco Bay Area represent the largest origins and destinations, despite a systemic decline in intra-state migration. Migration is strongly associated with population size, geographic proximity (i.e., distance and contiguity), job availability, and industrial composition similarity between origins and destinations. Our findings also highlight the contribution of shared origins, destinations, and regions in explaining the systematic variation of migration flows. Counties vary more in the number of migrants they attract than the number they send. The purposed multilevel modeling approach is useful in identifying place-specific influences on migration and in improving estimation accuracy.
    Supplementary information: The online version contains supplementary material available at 10.1007/s11113-023-09782-2.
    Language English
    Publishing date 2023-04-26
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2018638-1
    ISSN 1573-7829 ; 0167-5923
    ISSN (online) 1573-7829
    ISSN 0167-5923
    DOI 10.1007/s11113-023-09782-2
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  2. Thesis ; Online: Neodymium and Hafnium Isotope and Rare Earth Element Geochemical Cycling and Fluxes from the Amazon to the tropical western Atlantic

    Xu, Antao

    2024  

    Abstract: Continental margins are a dynamic interface linking the terrestrial lithosphere and oceanic hydrosphere, thus controlling fluxes of terrigenous materials from land to ocean. In particular, estuaries are places channeling vast amounts of minerals, ... ...

    Abstract Continental margins are a dynamic interface linking the terrestrial lithosphere and oceanic hydrosphere, thus controlling fluxes of terrigenous materials from land to ocean. In particular, estuaries are places channeling vast amounts of minerals, nutrients, organic matter and trace elements (TEs) in dissolved and particulate forms into the oceans. As many TEs are essential nutrients for phytoplankton growth, their concentrations ([TEs]) together with macronutrients in surface waters influence marine primary productivity, thereby impacting ocean ecosystems and carbon cycling. However, before entering the oceans, terrigenous TEs are modified at continental margins by various processes including removal, release and recycling. Consequently, studying geochemical cycling of TEs at continental margins is crucial for discerning their sources and processes that determine TE fluxes to oceans. Radiogenic neodymium (Nd) and hafnium (Hf) isotopic compositions, expressed as εNd and εHf, respectively are sensitive tracers of the origin and mixing of water masses and seawater-particle interactions at the continent-ocean interface. In this thesis a detailed investigation of the distributions of radiogenic Nd and Hf isotopes as well as rare earth elements and yttrium (REY) is performed across the Amazon freshwater plume, the Amazonian mangrove belt and the Amazon shelf and slope as part of the GEOTRACES GApr11 cruise. The objective is to investigate the sources and processes influencing the TE supplies, Nd and Hf isotope distributions and their fluxes to the western Atlantic Ocean.
    Subject code 551
    Language English
    Publishing country de
    Document type Thesis ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Book ; Article ; Online: Impact of agricultural support on environmental and climate objectives

    Xu, Ankai

    2023  

    Abstract: This note synthesises the available literature examining the impact of agricultural support on greenhouse gas (GHG) emissions as well as its impact on water, biodiversity, and land. In keeping with the Secretariat's impartiality, the note reports the ... ...

    Abstract This note synthesises the available literature examining the impact of agricultural support on greenhouse gas (GHG) emissions as well as its impact on water, biodiversity, and land. In keeping with the Secretariat's impartiality, the note reports the findings as they appear in the literature. The primary source of analysis is the work conducted by Ash and Cox (2022), supplemented by additional insights from recent literature on this subject.
    Keywords ddc:330 ; agriculture ; environment ; climate change
    Language English
    Publisher Geneva: World Trade Organization (WTO)
    Publishing country de
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Patient Access to Health Data: A Review of Philosophic and Healthcare Issues.

    Xu, Andrew / Chapman, Brian E

    Studies in health technology and informatics

    2024  Volume 310, Page(s) 1524–1525

    Abstract: In 2012 Australia created a national Personal Controlled Electronic Health Record (PCEHR) known as "My Health Record" (MHR). However, MHR has seen low patient utilization. Debate regarding MHR has centered on utility and moral issues (e.g. data privacy). ...

    Abstract In 2012 Australia created a national Personal Controlled Electronic Health Record (PCEHR) known as "My Health Record" (MHR). However, MHR has seen low patient utilization. Debate regarding MHR has centered on utility and moral issues (e.g. data privacy). We conducted a narrative review to assess patient perception and clinical utility of PCEHRs worldwide. Results show patient and clinician support for PCEHRs but little evidence of improved outcomes and patient concerns regarding data providence.
    MeSH term(s) Humans ; Australia ; Electronic Health Records ; Electronics ; Health Facilities ; Health Records, Personal
    Language English
    Publishing date 2024-01-25
    Publishing country Netherlands
    Document type Review ; Journal Article
    ISSN 1879-8365
    ISSN (online) 1879-8365
    DOI 10.3233/SHTI231275
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  5. Article ; Online: Clinical value of serum AFP and PIVKA-II for diagnosis, treatment and prognosis of hepatocellular carcinoma.

    Jin, Yujiao / Xu, Aifang

    Journal of clinical laboratory analysis

    2024  Volume 38, Issue 4, Page(s) e25016

    MeSH term(s) Humans ; Carcinoma, Hepatocellular/diagnosis ; Carcinoma, Hepatocellular/therapy ; alpha-Fetoproteins ; Liver Neoplasms/diagnosis ; Liver Neoplasms/therapy ; Biomarkers ; Prognosis ; Prothrombin ; Biomarkers, Tumor ; Protein Precursors
    Chemical Substances acarboxyprothrombin (53230-14-1) ; alpha-Fetoproteins ; Biomarkers ; Prothrombin (9001-26-7) ; Biomarkers, Tumor ; Protein Precursors
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Letter
    ZDB-ID 645095-7
    ISSN 1098-2825 ; 0887-8013
    ISSN (online) 1098-2825
    ISSN 0887-8013
    DOI 10.1002/jcla.25016
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  6. Article: Sleep Patterns During Pre-Competition Training Phase: A Comparison Between Male and Female Collegiate Swimmers.

    Xu, Anran / Li, Xiaotian

    Nature and science of sleep

    2024  Volume 16, Page(s) 369–379

    Abstract: Purpose: While there is a rising focus on sleep issues among athletes, a notable gap exists in the comparative analysis of sleep patterns between male and female athletes. This study aims to evaluate the sleep patterns of collegiate swimmers during a ... ...

    Abstract Purpose: While there is a rising focus on sleep issues among athletes, a notable gap exists in the comparative analysis of sleep patterns between male and female athletes. This study aims to evaluate the sleep patterns of collegiate swimmers during a specific period (pre-competition training phase) based on the National Sleep Foundation's recommendations and compares sleep differences between males and females.
    Patients and methods: 15 swimmers (6 males and 9 females) completed the Athlete Sleep Screening Questionnaire (ASSQ) and wore actigraphy devices for 8 consecutive nights to record objective sleep patterns including bedtime, wake time, sleep onset latency, total sleep time, wake after sleep onset, and sleep efficiency.
    Results: The total sleep time of collegiate male (5.0±0.4 h, 4.6 to 5.4h) and female (6.0±0.7 h, 5.5 to 6.5h) swimmers was less than 7 hours per night, and male swimmers' sleep efficiency (76.7±8.9%, 67.4 to 86.0%) was lower than the 85% standard. Male swimmers had less objectively measured sleep duration (p=0.006, d=1.66, large effect), lower sleep efficiency (p=0.013, d=1.51, large effect), and longer wake after sleep onset (p=0.096, d=0.94, moderate effect). Female swimmers had higher sleep difficulty scores (p=0.06, d=1.08, moderate effect), and there was a significant difference in the distribution of sleep difficulty scores between male and female swimmers (p=0.033, V=0.045, small effect).
    Conclusion: Collegiate swimmers exhibited poor sleep patterns during pre-competition preparation, and the sleep fragmentation of male swimmers was more pronounced. There were sex differences in both subjective and objective measured sleep patterns, with male swimmers having less sleep and low efficiency, while female swimmers experienced more significant sleep disturbances.
    Language English
    Publishing date 2024-04-13
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2587468-8
    ISSN 1179-1608
    ISSN 1179-1608
    DOI 10.2147/NSS.S444472
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  7. Article: Retinal ganglion cells undergo cell typeâ€"specific functional changes in a biophysically detailed model of retinal degeneration.

    Xu, Aiwen / Beyeler, Michael

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Understanding the retina in health and disease is a key issue for neuroscience and neuroengineering applications such as retinal prostheses. During degeneration, the retinal network undergoes complex and multi-stage neuroanatomical alterations, which ... ...

    Abstract Understanding the retina in health and disease is a key issue for neuroscience and neuroengineering applications such as retinal prostheses. During degeneration, the retinal network undergoes complex and multi-stage neuroanatomical alterations, which drastically impact the retinal ganglion cell (RGC) response and are of clinical importance. Here we present a biophysically detailed
    Language English
    Publishing date 2023-01-16
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.01.13.523982
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  8. Article: Retinal ganglion cells undergo cell type-specific functional changes in a computational model of cone-mediated retinal degeneration.

    Xu, Aiwen / Beyeler, Michael

    Frontiers in neuroscience

    2023  Volume 17, Page(s) 1147729

    Abstract: Introduction: Understanding the retina in health and disease is a key issue for neuroscience and neuroengineering applications such as retinal prostheses. During degeneration, the retinal network undergoes complex and multi-stage neuroanatomical ... ...

    Abstract Introduction: Understanding the retina in health and disease is a key issue for neuroscience and neuroengineering applications such as retinal prostheses. During degeneration, the retinal network undergoes complex and multi-stage neuroanatomical alterations, which drastically impact the retinal ganglion cell (RGC) response and are of clinical importance. Here we present a biophysically detailed
    Methods: The model included 11, 138 cells belonging to nine different cell types (cone photoreceptors, horizontal cells, ON/OFF bipolar cells, ON/OFF amacrine cells, and ON/OFF ganglion cells) confined to a 300 × 300 × 210μm patch of the parafoveal retina. After verifying that the model reproduced seminal findings about the light response of retinal ganglion cells (RGCs), we systematically introduced anatomical and neurophysiological changes (e.g., reduced light sensitivity of photoreceptor, cell death, cell migration) to the network and studied their effect on network activity.
    Results: The model was not only able to reproduce common findings about RGC activity in the degenerated retina, such as hyperactivity and increased electrical thresholds, but also offers testable predictions about the underlying neuroanatomical mechanisms.
    Discussion: Overall, our findings demonstrate how biophysical changes typified by cone-mediated retinal degeneration may impact retinal responses to light and electrical stimulation. These insights may further our understanding of retinal processing and inform the design of retinal prostheses.
    Language English
    Publishing date 2023-05-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/fnins.2023.1147729
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  9. Article ; Online: Current status and future perspectives of FGF21 analogues in clinical trials.

    Chui, Zara Siu Wa / Shen, Qing / Xu, Aimin

    Trends in endocrinology and metabolism: TEM

    2024  

    Abstract: Recent advances in fibroblast growth factor 21 (FGF21) biology and pharmacology have led to the development of several long-acting FGF21 analogues and antibody-based mimetics now in various phases of clinical trials for the treatment of obesity-related ... ...

    Abstract Recent advances in fibroblast growth factor 21 (FGF21) biology and pharmacology have led to the development of several long-acting FGF21 analogues and antibody-based mimetics now in various phases of clinical trials for the treatment of obesity-related metabolic comorbidities. The efficacy of these FGF21 analogues/mimetics on glycaemic control and weight loss is rather mild and inconsistent; nevertheless, several promising therapeutic benefits have been reproducibly observed in most clinical studies, including amelioration of dyslipidaemia (particularly hypertriglyceridaemia) and hepatic steatosis, reduction of biomarkers of liver fibrosis and injury, and resolution of metabolic dysfunction-associated steatohepatitis (MASH). Evidence is emerging that combination therapy with FGF21 analogues and other hormones (such as glucagon-like peptide 1; GLP-1) can synergise their pharmacological benefits, thus maximising the therapeutic efficacy for obesity and its comorbidities.
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1042384-9
    ISSN 1879-3061 ; 1043-2760
    ISSN (online) 1879-3061
    ISSN 1043-2760
    DOI 10.1016/j.tem.2024.02.001
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  10. Article ; Online: MALT Lymphoma of the Esophagus.

    Lian, Jingjing / Xu, Aiping / Xu, Meidong

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2024  

    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2024.02.016
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