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  1. Article: [Analysis of epidemiological characteristics and risk factors of catheter-associated urinary tract infections in patients with perineal and/or hip burns].

    Zheng, X X / Kong, L A / Lyu, R / Xu, C J

    Zhonghua shao shang yu chuang mian xiu fu za zhi

    2024  Volume 40, Issue 3, Page(s) 289–295

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Male ; Female ; Humans ; Tigecycline ; Retrospective Studies ; Anti-Infective Agents ; Burns/complications ; Ciprofloxacin ; Urinary Tract Infections/epidemiology ; Risk Factors ; Catheters ; Hypoproteinemia/complications ; Diabetes Complications/complications
    Chemical Substances Tigecycline (70JE2N95KR) ; Anti-Infective Agents ; Ciprofloxacin (5E8K9I0O4U)
    Language Chinese
    Publishing date 2024-03-29
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 2097-1109
    ISSN 2097-1109
    DOI 10.3760/cma.j.cn501225-20231027-00138
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Progress of artificial intelligence in gynecological oncology].

    Chen, M X / Gao, Y / Kang, Y / Xu, C J

    Zhonghua fu chan ke za zhi

    2023  Volume 57, Issue 1, Page(s) 72–78

    MeSH term(s) Female ; Humans ; Artificial Intelligence ; Genital Neoplasms, Female/therapy
    Language Chinese
    Publishing date 2023-05-16
    Publishing country China
    Document type Journal Article
    ZDB-ID 604570-4
    ISSN 0529-567X
    ISSN 0529-567X
    DOI 10.3760/cma.j.cn112141-20210924-00549
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Current status and research advances on catheter-associated urinary tract infection in burn patients].

    Zheng, X X / Shi, P / Feng, H L / Lyu, R / Xu, C J / Chen, Z W

    Zhonghua shao shang yu chuang mian xiu fu za zhi

    2023  Volume 39, Issue 6, Page(s) 581–585

    Abstract: Catheter-associated urinary tract infection (CAUTI) is one of the common nosocomial infections in burn patients. It not only extends the length of hospital stay of patients, increases the economic burden on family and society, but also seriously affects ... ...

    Abstract Catheter-associated urinary tract infection (CAUTI) is one of the common nosocomial infections in burn patients. It not only extends the length of hospital stay of patients, increases the economic burden on family and society, but also seriously affects the prognosis and quality of life of patients, increases the risk of death of patients. In this paper, the epidemiological characteristics, influencing factors, and prevention measures of CAUTI in burn patients are reviewed to draw high attention of clinical medical staff and to provide some reference for clinical practice.
    MeSH term(s) Humans ; Burns/complications ; Burns/therapy ; Catheter-Related Infections/epidemiology ; Catheter-Related Infections/prevention & control ; Catheters ; Cross Infection/prevention & control ; Quality of Life ; Urinary Tract Infections/epidemiology ; Urinary Tract Infections/etiology ; Urinary Tract Infections/prevention & control
    Language Chinese
    Publishing date 2023-10-05
    Publishing country China
    Document type English Abstract ; Journal Article ; Review
    ISSN 2097-1109
    ISSN 2097-1109
    DOI 10.3760/cma.j.cn501225-20220904-00378
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [New progress in the diagnosis and treatment of natal teeth and neonatal teeth].

    He, X F / Xu, C J

    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology

    2019  Volume 54, Issue 6, Page(s) 425–428

    Abstract: There were great individual differences in eruption time of the teeth. Generally speaking, the deciduous teeth begin to erupt at 6 months after birth, but some babies are born with erupted teeth, which are called natal teeth; in addition, teeth erupted ... ...

    Abstract There were great individual differences in eruption time of the teeth. Generally speaking, the deciduous teeth begin to erupt at 6 months after birth, but some babies are born with erupted teeth, which are called natal teeth; in addition, teeth erupted within 30 days after the baby is born are called neonatal teeth. Natal teeth and neonatal teeth may cause ulceration, aspiration, and nipple pain or trauma in the mother's breast during the time of breastfeeding. Extraction of the teeth may cause complications such as neonatal osteomyelitis. To avoid the complications caused by these diseases, and to alleviate the suffering of patients and their families, this article will introduce the clinical manifestations, etiology and related complications of natal teeth and neonatal teeth, and then give some treatment methods and nursing methods, especially to help clinical work.
    MeSH term(s) Humans ; Infant ; Infant, Newborn ; Natal Teeth ; Osteomyelitis ; Tooth Eruption ; Tooth Extraction
    Language Chinese
    Publishing date 2019-06-08
    Publishing country China
    Document type Journal Article
    ZDB-ID 1027950-7
    ISSN 1002-0098
    ISSN 1002-0098
    DOI 10.3760/cma.j.issn.1002-0098.2019.06.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Laterally extended endopelvic resection for advanced or recurrent gynecological malignancies: clinicopathological analysis].

    Yao, L Q / Zou, R Y / Yuan, L / Chen, M / Xu, C J

    Zhonghua yi xue za zhi

    2022  Volume 102, Issue 26, Page(s) 2026–2029

    Abstract: To explore the feasibility and safety of laterally extended endopelvic resection (LEER) for advanced and recurrent gynecological malignancies with pelvic sidewall involvement and to evaluate this therapeutic potential of this novel salvage treatment. The ...

    Abstract To explore the feasibility and safety of laterally extended endopelvic resection (LEER) for advanced and recurrent gynecological malignancies with pelvic sidewall involvement and to evaluate this therapeutic potential of this novel salvage treatment. The clinicopathological data of 5 patients with gynecological malignancies who received laparoscopic LEER treatment in Obstetrics and Gynecology Hospital of Fudan University from January 2019 to September 2021 were retrospectively analyzed, including 3 cases of recurrent cervical cancer, 1 case of primary advanced endometrial cancer and 1 case of pelvic aggressive angiomyxoma. Among them, four patients achieved complete resection (R0) with a negative resection margin; the other patient with recurrent cervical cancer did not complete surgery because of the extreme risk of continuing surgery. The median operation time was 345 (225-482) minutes and the median blood loss was approximately 300 (200-600) ml. Complications occurred in three patients, including lymphocysts, urinary tract infections, and deep venous thrombosis of the lower extremities. Within a median follow-up time of 283 (128-715) days, 4 patients survived tumor-free, and 1 patient died. The high rate of complete resection (R0) and the encouraging oncological outcomes suggest that LEER may be an alternative treatment option for patients with advanced and recurrent gynecological malignancies involving the pelvic sidewall.
    MeSH term(s) Female ; Gynecology ; Humans ; Hysterectomy ; Lymph Node Excision ; Neoplasm Recurrence, Local/surgery ; Retrospective Studies ; Uterine Cervical Neoplasms/pathology ; Uterine Cervical Neoplasms/surgery
    Language Chinese
    Publishing date 2022-05-25
    Publishing country China
    Document type Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20211028-02393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [Research progress on moderate and deep sedation during wound dressing change in pediatric burn patients].

    Feng, H L / Wang, S / Xiang, Q / Xu, C J / Zhong, Y / Zheng, X X / You, M / Lan, L

    Zhonghua shao shang yu chuang mian xiu fu za zhi

    2023  Volume 39, Issue 1, Page(s) 96–100

    Abstract: Moderate and deep sedation can effectively relieve or eliminate the pain and body discomfort during wound dressing change in pediatric burn patients, relieve anxiety, agitation, and even delirium of the children, reduce the metabolic rate of the children, ...

    Abstract Moderate and deep sedation can effectively relieve or eliminate the pain and body discomfort during wound dressing change in pediatric burn patients, relieve anxiety, agitation, and even delirium of the children, reduce the metabolic rate of the children, make them in a quiet, comfortable, and cooperative state, which is conducive to the smooth completion of dressing change. This paper summarized the three aspects of moderate and deep sedation in pediatric burn patients, including the overview, main points of implementation, and effects, and further introduced the moderate and deep sedation medication regimens for different routes of administration, as well as the content of evaluation and monitoring. Suggestions on the prevention and management of related complications and the management of moderate and deep sedation implementation procedures were put forward, in order to provide references for the development of moderate and deep sedation for wound dressing change in pediatric burn patients in China.
    MeSH term(s) Child ; Humans ; Bandages/adverse effects ; Burns/complications ; Burns/therapy ; Deep Sedation ; Pain/complications ; Pain Management/methods
    Language Chinese
    Publishing date 2023-02-03
    Publishing country China
    Document type English Abstract ; Journal Article ; Review
    ISSN 2097-1109
    ISSN 2097-1109
    DOI 10.3760/cma.j.cn501225-20220421-00153
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Influence of disposable diaper dependence on emotional behavior and related factors of preschool-aged children].

    Xu, C J / Yu, J T / Yang, J / Yang, S / Zhou, Z K / Wen, Y B / Shang, X P / Wen, J G

    Zhonghua yi xue za zhi

    2023  Volume 103, Issue 46, Page(s) 3770–3775

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Child ; Male ; Female ; Humans ; Child, Preschool ; Fecal Incontinence ; Emotions ; Problem Behavior/psychology ; Surveys and Questionnaires ; Urinary Incontinence ; Urinary Tract Infections
    Language Chinese
    Publishing date 2023-12-13
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 132513-9
    ISSN 0376-2491
    ISSN 0376-2491
    DOI 10.3760/cma.j.cn112137-20230310-00367
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: [Study on static parameters of internal nasal valve in 3-dimensional model of nasal cavity space].

    Chen, J Y / Wang, T / Wang, P H / Sun, Y Y / Xue, N / Xu, C J / Shi, R J

    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery

    2023  Volume 58, Issue 3, Page(s) 206–211

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Adult ; Female ; Humans ; Male ; Young Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Nasal Cavity/diagnostic imaging ; Retrospective Studies ; China ; Nose ; Nasal Bone
    Language Chinese
    Publishing date 2023-03-07
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2195655-8
    ISSN 1673-0860
    ISSN 1673-0860
    DOI 10.3760/cma.j.cn115330-20220618-00357
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: [Application effects of feedforward control theory in the rollover bed treatment of mass patients with burn-explosion combined injury].

    Chen, H Q / Feng, X Q / Xu, C J / Zhang, Y P / Zeng, F / Zhong, Z A / Xia, Y L / Han, C M

    Zhonghua shao shang yu chuang mian xiu fu za zhi

    2022  Volume 38, Issue 4, Page(s) 373–377

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Blood Gas Analysis ; Burns/therapy ; Explosions ; Female ; Humans ; Male ; Respiratory Distress Syndrome ; Retrospective Studies
    Language Chinese
    Publishing date 2022-04-21
    Publishing country China
    Document type Journal Article
    ISSN 2097-1109
    ISSN 2097-1109
    DOI 10.3760/cma.j.cn501120-20201202-00514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Leptin promotes proliferation and inhibits apoptosis of prostate cancer cells by regulating ERK1/2 signaling pathway.

    Xu, C-J / Dong, L-L / Kang, X-L / Li, Z-M / Zhang, H-Y

    European review for medical and pharmacological sciences

    2020  Volume 24, Issue 16, Page(s) 8341–8348

    Abstract: Objective: The aim of this study was to investigate the effect of leptin (Lep) on the proliferation, invasion and apoptosis of prostate cancer cells through the extracellular regulated protein kinase 1/2 (ERK1/2) signaling pathway.: Materials and ... ...

    Abstract Objective: The aim of this study was to investigate the effect of leptin (Lep) on the proliferation, invasion and apoptosis of prostate cancer cells through the extracellular regulated protein kinase 1/2 (ERK1/2) signaling pathway.
    Materials and methods: Prostate cancer DU145 cells in the logarithmic growth phase were randomly divided into Lep (10, 20, 40, 80, 160 and 320 ng/mL) groups and blank control (Con) group. After culture, the cells were treated for 6 h, 12 h and 24 h, respectively. The effects of Lep on the proliferation and invasion of DU145 cells were detected via methyl thiazolyl tetrazolium (MTT) assay and transwell chamber assay, respectively. Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) was carried out to examine the messenger ribonucleic acid (mRNA) expressions of ERK1/2, b-cell lymphoma 2 (Bcl-2) and Bcl-2-associated X protein (Bax) in DU145 cells after Lep treatment for 24 h. Thereafter, immunofluorescence assay was performed to detect the localization of ERK1/2 protein in prostate cancer DU145 cells. In addition, the expressions of phosphorylated (p)-ERK, ERK1/2 and apoptosis-related proteins, Bcl-2, Bax and cleaved cysteinyl aspartate specific proteinase (c-Caspase 3) in prostate cancer DU145 cells after treatment with different concentrations of Lep for 24 h were examined by Western blotting.
    Results: MTT assay results showed that the proliferation rate of DU145 cells increased significantly at 6 h, 12 h and 24 h after 5-320 ng/mL of Lep treatment (p<0.05). Transwell assay manifested that the number of invasive cells was significantly raised after Lep treatment for 24 h (p<0.05). Meanwhile, the invasion ability of cells increased gradually with the elevation of Lep concentration. Subsequent qRT-PCR results demonstrated that after treatment with different concentrations of Lep, the mRNA expressions of ERK1/2 and Bcl-2 rose markedly (p<0.05). However, the mRNA expression of Bax was remarkably down-regulated (p<0.05) with the increase of Lep concentration in a concentration-dependent manner. According to the detection using a laser scanning confocal microscope, ERK1/2 red fluorescence showed punctiform aggregation, which was gradually raised with the increase of Lep concentration for 24 h. Moreover, Western blotting results denoted that with the increase of Lep concentration, the protein expressions of p-ERK, ERK1/2 and Bcl-2 were notably elevated (p<0.05), while those of Bax and c-Caspase 3 were distinctly reduced (p<0.05).
    Conclusions: Lep activation induces the proliferation, promotes the invasion and inhibits the apoptosis of prostate cancer cells through the ERK1/2 signaling pathway.
    MeSH term(s) Apoptosis ; Cell Proliferation ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Humans ; Leptin/metabolism ; Male ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology ; Signal Transduction ; Tumor Cells, Cultured
    Chemical Substances LEP protein, human ; Leptin ; Extracellular Signal-Regulated MAP Kinases (EC 2.7.11.24)
    Language English
    Publishing date 2020-09-06
    Publishing country Italy
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202008_22630
    Database MEDical Literature Analysis and Retrieval System OnLINE

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