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  1. Article: Clinical Analysis of Interventional Therapy for Eight Cases of Extracranial ICA Aneurysm.

    Xu, Jian-Feng / Liu, Zao-Bin / Wang, Tong / Liu, Yang

    Pakistan journal of medical sciences

    2021  Volume 37, Issue 4, Page(s) 1086–1092

    Abstract: Objective: To explore the interventional therapy and clinical efficacy of extracranial ICA aneurysm.: Methods: The clinical data of eight patients with extracranial ICA aneurysm treated by interventional stent implantation from December 2014 to ... ...

    Abstract Objective: To explore the interventional therapy and clinical efficacy of extracranial ICA aneurysm.
    Methods: The clinical data of eight patients with extracranial ICA aneurysm treated by interventional stent implantation from December 2014 to February 2018 in the Neurosurgery Department of the Third Hospital of Mianyang were analyzed. And this research was a retrospective analysis. All patients underwent digital subtraction angiography (DSA) and were diagnosed with extracranial carotid artery aneurysm. These patients, therefore, were treated with interventional stent implantation.
    Results: Interventional treatment was successfully conducted on all eight patients. In eight patients, the aneurysm cavity was not developed immediately after angiography, and in one case, the aneurysm cavity was developed with coil-assisted embolization. All the internal carotid arteries were well developed, with no complications such as intraoperative rupture, bleeding and thrombosis occur. Follow-up for three months to two years showed that the patients recovered well, the GOS score was 4 points for patients with cerebral infarction, and the rest reached five points. Follow-up CTA showed no signs of aneurysm recurrence or ICA restenosis.
    Conclusion: Interventional stent placement is a preferable and relatively safe method for the treatment of extracranial carotid artery aneurysm with less trauma and short operation time.
    Language English
    Publishing date 2021-07-09
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 2032827-8
    ISSN 1681-715X ; 1682-024X ; 1017-4699
    ISSN (online) 1681-715X
    ISSN 1682-024X ; 1017-4699
    DOI 10.12669/pjms.37.4.3957
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Cobalt-catalyzed enantioselective desymmetrizing reductive cyclization of alkynyl cyclodiketones.

    Liang, Ren-Xiao / Tang, Heng-Wei / Liu, Jia-Liang / Xu, Jian-Feng / Chen, Ling-Jia / Jia, Yi-Xia

    Chemical science

    2023  Volume 14, Issue 23, Page(s) 6393–6398

    Abstract: A highly enantioselective cobalt-catalyzed desymmetrizing reductive cyclization of alkynyl cyclodiketones has been developed. Under mild reaction conditions by employing HBpin as a reducing agent and ferrocene-based PHOX as a chiral ligand, a series of ... ...

    Abstract A highly enantioselective cobalt-catalyzed desymmetrizing reductive cyclization of alkynyl cyclodiketones has been developed. Under mild reaction conditions by employing HBpin as a reducing agent and ferrocene-based PHOX as a chiral ligand, a series of polycyclic tertiary allylic alcohols bearing contiguous quaternary stereocenters are achieved in moderate to excellent yields with excellent enantioselectivities (up to 99%). Broad substrate scope and high functional group compatibility are observed in this reaction. A CoH-catalyzed pathway involving alkyne hydrocobaltation followed by nucleophilic addition to the C[double bond, length as m-dash]O bond is proposed. Synthetic transformations of the product are conducted to demonstrate the practical utilities of this reaction.
    Language English
    Publishing date 2023-05-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d3sc00119a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Right paraduodenal hernia, classification, and selection of surgical methods: a case report and review of the literature.

    Wang, Xiao-Long / Jin, Gui-Xiu / Xu, Jian-Feng / Chen, Zhi-Rong / Wu, Li-Meng / Jiang, Zhi-Long

    Journal of medical case reports

    2023  Volume 17, Issue 1, Page(s) 536

    Abstract: Background: Considering that right paraduodenal hernia is a rare internal hernia with abnormal anatomy and is often encountered during an emergency, surgeons may lack knowledge about it and choose incorrect treatment. Thus, this case report is a helpful ...

    Abstract Background: Considering that right paraduodenal hernia is a rare internal hernia with abnormal anatomy and is often encountered during an emergency, surgeons may lack knowledge about it and choose incorrect treatment. Thus, this case report is a helpful complement to the few previously reported cases of right paraduodenal hernia. Additionally, we reviewed all the reported right paraduodenal hernia cases and proposed appropriate surgical strategies according to different anatomical features.
    Case presentation: The case involved a 33-year-old Chinese male patient who was admitted to the hospital due to abdominal pain. The patient was initially diagnosed with small bowel obstruction, and conservative treatment failed. An emergency operation was arranged, during which a diagnosis of right paraduodenal hernia was made instead. After surgery, the patient recovered well without abdominal pain for 2 years.
    Conclusion: Although right paraduodenal hernia accounts only for a small proportion of paraduodenal hernia, its anatomical characteristics can vary considerably. We divided right paraduodenal hernia into three types, with each type requiring a different surgical strategy.
    MeSH term(s) Male ; Humans ; Adult ; Paraduodenal Hernia/complications ; Paraduodenal Hernia/surgery ; Hernia, Abdominal/diagnostic imaging ; Hernia, Abdominal/surgery ; Hernia, Abdominal/complications ; Intestine, Small/surgery ; Herniorrhaphy/adverse effects ; Abdominal Pain/etiology ; Duodenal Diseases/diagnostic imaging ; Duodenal Diseases/surgery
    Language English
    Publishing date 2023-12-30
    Publishing country England
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-023-04286-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Diagnostic Value of MRI Features in Dual-phenotype Hepatocellular Carcinoma: A Preliminary Study.

    Gu, Hong-Xian / Huang, Xiao-Shan / Xu, Jian-Xia / Zhu, Ping / Xu, Jian-Feng / Fan, Shu-Feng

    Journal of digital imaging

    2023  Volume 36, Issue 6, Page(s) 2554–2566

    Abstract: This study aimed to explore the magnetic resonance imaging (MRI) features of dual-phenotype hepatocellular carcinoma (DPHCC) and their diagnostic value.The data of 208 patients with primary liver cancer were retrospectively analysed between January 2016 ... ...

    Abstract This study aimed to explore the magnetic resonance imaging (MRI) features of dual-phenotype hepatocellular carcinoma (DPHCC) and their diagnostic value.The data of 208 patients with primary liver cancer were retrospectively analysed between January 2016 and June 2021. Based on the pathological diagnostic criteria, 27 patients were classified into the DPHCC group, 113 patients into the noncholangiocyte-phenotype hepatocellular carcinoma (NCPHCC) group, and 68 patients with intrahepatic cholangiocarcinoma (ICC) were classified into the ICC group. Two abdominal radiologists reviewed the preoperative MRI features by a double-blind method. The MRI features and key laboratory and clinical indicators were compared between the groups. The potentially valuable MRI features and key laboratory and clinical characteristics for predicting DPHCC were identified by univariate and multivariate analyses, and the odds ratios (ORs) were recorded. In multivariate analysis, tumour without capsule (P = 0.046, OR = 9.777), dynamic persistent enhancement (P = 0.006, OR = 46.941), and targetoid appearance on diffusion-weighted imaging (DWI) (P = 0.021, OR = 30.566) were independently significant factors in the detection of DPHCC compared to NCPHCC. Serum alpha-fetoprotein (AFP) > 20 µg/L (P = 0.036, OR = 67.097) and prevalence of hepatitis B virus (HBV) infection (P = 0.020, OR = 153.633) were independent significant factors in predicting DPHCC compared to ICC. The differences in other tumour marker levels and imaging features between the groups were not significant. In MR enhanced and diffusion imaging, tumour without capsule, persistent enhancement and DWI targetoid findings, combined with AFP > 20 µg/L and HBV infection-positive laboratory results, can help to diagnose DPHCC and differentiate it from NCPHCC and ICC. These results suggest that clinical, laboratory and MRI features should be integrated to construct an AI diagnostic model for DPHCC.
    MeSH term(s) Humans ; alpha-Fetoproteins ; Bile Duct Neoplasms/pathology ; Bile Ducts, Intrahepatic ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/pathology ; Cholangiocarcinoma/pathology ; Cholangiocarcinoma/surgery ; Contrast Media ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/pathology ; Magnetic Resonance Imaging/methods ; Phenotype ; Retrospective Studies ; Double-Blind Method
    Chemical Substances alpha-Fetoproteins ; Contrast Media
    Language English
    Publishing date 2023-08-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1033897-4
    ISSN 1618-727X ; 0897-1889
    ISSN (online) 1618-727X
    ISSN 0897-1889
    DOI 10.1007/s10278-023-00888-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Cellulomonas taurus sp. nov., a novel bacteria with multiple hydrolase activity isolated from livestock, and potential application in wastewater treatment.

    Zhang, Sha-Sha / Xu, Jian-Feng / Sun, Xiao-Li / Guo, Wei / Liu, Zeng-Shan

    Antonie van Leeuwenhoek

    2021  Volume 114, Issue 5, Page(s) 527–538

    Abstract: A Gram-positive, smooth, sub-transparent, faint yellow,0.5-0.7 µm diameter, rod shaped aerobic or facultative aerobic strain P40- ... ...

    Abstract A Gram-positive, smooth, sub-transparent, faint yellow,0.5-0.7 µm diameter, rod shaped aerobic or facultative aerobic strain P40-2
    MeSH term(s) Animals ; Bacterial Typing Techniques ; Base Composition ; Cellulomonas/genetics ; DNA, Bacterial/genetics ; Fatty Acids/analysis ; Hydrolases ; Livestock ; Mice ; Phospholipids/analysis ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Sequence Analysis, DNA ; Swine ; Vitamin K 2 ; Water Purification
    Chemical Substances DNA, Bacterial ; Fatty Acids ; Phospholipids ; RNA, Ribosomal, 16S ; Vitamin K 2 (11032-49-8) ; Hydrolases (EC 3.-)
    Language English
    Publishing date 2021-03-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 214861-4
    ISSN 1572-9699 ; 0003-6072
    ISSN (online) 1572-9699
    ISSN 0003-6072
    DOI 10.1007/s10482-021-01538-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Dissecting the molecular mechanism of russeting in sand pear (Pyrus pyrifolia Nakai) by metabolomics, transcriptomics, and proteomics.

    Shi, Chun-Hui / Wang, Xiao-Qing / Xu, Jian-Feng / Zhang, Yu-Xing / Qi, Baoxiu / Jun, Luo

    The Plant journal : for cell and molecular biology

    2021  Volume 108, Issue 6, Page(s) 1644–1661

    Abstract: Brown coloration and a rough appearance as russet and semi-russet (partial russet) are features unique to the popular Asian sand pear (Pyrus pyrifolia Nakai). The degree of russeting is different between different genotypes. Russeting is sensitive to ... ...

    Abstract Brown coloration and a rough appearance as russet and semi-russet (partial russet) are features unique to the popular Asian sand pear (Pyrus pyrifolia Nakai). The degree of russeting is different between different genotypes. Russeting is sensitive to water fluctuations, where excessive rainwater can trigger/stimulate its development. However, the molecular mechanism of russeting is currently unclear. Here, we employed multi-omics, i.e., metabolomics, transcriptomics, and proteomics, and analyzed the effect of different sand pear genotypes and artificial rainfall on russeting of pear fruits. This led to the identification of 79, 64, and 29 differentially produced/expressed metabolites, transcripts, and proteins that are involved in the biosynthesis of suberin, phenylpropane, cutin, and waxes. Further analysis of these differentially expressed genes and their encoded proteins revealed that four of them exhibited high expression at both transcript and protein levels. Transient expression of one such gene, PbHHT1 (accession number 103966555), which encodes ω-hydroxypalmitate-O-feruloyl transferase, in young green non-russet fruits triggered premature suberization in the russeting pear genotypes. This coincided with increased production of 16-feruloyloxypalmitic acid, a conjugated compound between phenols and esters during the polymerization for suberin formation. Collectively, our data from the combined three omics demonstrate that russeting in sand pear is a complex process involving the biosynthesis and transport of suberin and many other secondary metabolites.
    MeSH term(s) China ; Fruit/genetics ; Fruit/metabolism ; Fruit/physiology ; Gene Expression Regulation, Plant ; Genotype ; Metabolomics ; Microscopy, Electron, Scanning ; Plant Proteins/genetics ; Plant Proteins/metabolism ; Pyrus/genetics ; Pyrus/metabolism ; Pyrus/physiology
    Chemical Substances Plant Proteins
    Language English
    Publishing date 2021-10-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1088037-9
    ISSN 1365-313X ; 0960-7412
    ISSN (online) 1365-313X
    ISSN 0960-7412
    DOI 10.1111/tpj.15532
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Chemical Constituents from Glycosmis pentaphylla].

    Chen, Li / Xu, Jian-feng / Sun, Li-chun

    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

    2018  Volume 39, Issue 1, Page(s) 90–93

    Abstract: Objective: To study the chemical constituents of Glycosmis pentaphylla.: Methods: 95% ethanolic extract of Glycosmis pentaphylla was fractioned and separated extensively by silica gel, Sephadex LH-20 chromatography,their structures were elucidated by ...

    Abstract Objective: To study the chemical constituents of Glycosmis pentaphylla.
    Methods: 95% ethanolic extract of Glycosmis pentaphylla was fractioned and separated extensively by silica gel, Sephadex LH-20 chromatography,their structures were elucidated by means of spectral data analysis.
    Results: All compounds were isolated and identified as 5,7,4’-trihydroxydihydroflavonol( 1),aromadendrin( 2),trans-dihydroquercetin( 3),cis-dihydroquercetin( 4),kaempferol( 5),quercetin( 6),5,7,4’-trihydroxyflavonol-3-O-α-L-rhamnopyranoside( 7),quercetin-3-O-α-L-arabinofuranoside( 8),quercetin-3-O-α-L-rhamnopyranoside( 9),5,7,3’,4’-tetrahydroxyflavonone-3-O-rhamnopyranoside( 1→6) glucopyranoside( 10) and 5,7,3’-trihydroxy-4’-methyl ether-flavonone-3-O-rhamnopyranoside( 1→6) glucopyranoside( 11).
    Conclusion: All compounds are isolated from this plant for the first time.
    MeSH term(s) Arabinose/analogs & derivatives ; Drugs, Chinese Herbal ; Flavonoids ; Glycosides ; Kaempferols ; Quercetin/analogs & derivatives ; Rhamnose/analogs & derivatives ; Rutaceae
    Chemical Substances Drugs, Chinese Herbal ; Flavonoids ; Glycosides ; Kaempferols ; quercetin-3-O-alpha-L-rhamnopyranoside ; quercetin-3-O-alpha-arabinofuranoside ; methyl rhamnopyranoside (14917-55-6) ; kaempferol (731P2LE49E) ; aromadedrin (7YA4640575) ; Quercetin (9IKM0I5T1E) ; taxifolin (9SOB9E3987) ; Arabinose (B40ROO395Z) ; Rhamnose (QN34XC755A)
    Language Chinese
    Publishing date 2018-08-06
    Publishing country China
    Document type Journal Article
    ISSN 1001-4454
    ISSN 1001-4454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Dissecting the molecular mechanism of russeting in sand pear (Pyrus pyrifolia Nakai) by metabolomics, transcriptomics, and proteomics

    Shi, Chun‐Hui / Wang, Xiao‐Qing / Xu, Jian‐Feng / Zhang, Yu‐Xing / Qi, Baoxiu / Jun, Luo

    plant journal. 2021 Dec., v. 108, no. 6

    2021  

    Abstract: Brown coloration and a rough appearance as russet and semi‐russet (partial russet) are features unique to the popular Asian sand pear (Pyrus pyrifolia Nakai). The degree of russeting is different between different genotypes. Russeting is sensitive to ... ...

    Abstract Brown coloration and a rough appearance as russet and semi‐russet (partial russet) are features unique to the popular Asian sand pear (Pyrus pyrifolia Nakai). The degree of russeting is different between different genotypes. Russeting is sensitive to water fluctuations, where excessive rainwater can trigger/stimulate its development. However, the molecular mechanism of russeting is currently unclear. Here, we employed multi‐omics, i.e., metabolomics, transcriptomics, and proteomics, and analyzed the effect of different sand pear genotypes and artificial rainfall on russeting of pear fruits. This led to the identification of 79, 64, and 29 differentially produced/expressed metabolites, transcripts, and proteins that are involved in the biosynthesis of suberin, phenylpropane, cutin, and waxes. Further analysis of these differentially expressed genes and their encoded proteins revealed that four of them exhibited high expression at both transcript and protein levels. Transient expression of one such gene, PbHHT1 (accession number 103966555), which encodes ω‐hydroxypalmitate‐O‐feruloyl transferase, in young green non‐russet fruits triggered premature suberization in the russeting pear genotypes. This coincided with increased production of 16‐feruloyloxypalmitic acid, a conjugated compound between phenols and esters during the polymerization for suberin formation. Collectively, our data from the combined three omics demonstrate that russeting in sand pear is a complex process involving the biosynthesis and transport of suberin and many other secondary metabolites.
    Keywords Pyrus pyrifolia ; biosynthesis ; color ; cutin ; gene expression regulation ; genes ; metabolomics ; multiomics ; pears ; polymerization ; proteomics ; rain ; secondary metabolites ; suberin ; suberization ; transcriptomics
    Language English
    Dates of publication 2021-12
    Size p. 1644-1661.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 1088037-9
    ISSN 1365-313X ; 0960-7412
    ISSN (online) 1365-313X
    ISSN 0960-7412
    DOI 10.1111/tpj.15532
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: Prediction of Long-Term Survival Outcome by Lymph Node Ratio in Patients of Parotid Gland Cancer: A Retrospective study.

    Jiang, Wen-Mei / Xu, Jian-Feng / Chen, Jun / Li, Guo-Li / Gao, Yun-Fei / Zhang, Quan / Chen, Yan-Feng

    Frontiers in surgery

    2022  Volume 9, Page(s) 903576

    Abstract: Background: Lymph node ratio (LNR) has been reported to reliably predict cancer-specific survival (CSS) in parotid gland cancer (PGC). Our study was designed to validate the significance of LNR in patients with PGC.: Methods: Patients diagnosed with ... ...

    Abstract Background: Lymph node ratio (LNR) has been reported to reliably predict cancer-specific survival (CSS) in parotid gland cancer (PGC). Our study was designed to validate the significance of LNR in patients with PGC.
    Methods: Patients diagnosed with stage I-IV PGC were enrolled from Surveillance Epidemiology and End Results database (SEER,
    Results: The optimal cutoff value of LNR was 0.32 by X-tile based on 3529 patients from SEER. Cox proportional hazard regression analysis revealed better CSS for patients with LNR ≤ 0.32 (adjusted hazard ratio [HR] 1.612, 95% confidence interval [95% CI] 1.286-2.019;
    Conclusions: In conclusion, the lymph node ratio turned out to be an independent prognostic factor for cancer-specific survival of PGC in this study. This valuable information could help clinicians to evaluate the prognosis of PGC and suggest that adequate lymph node dissection is necessary.
    Language English
    Publishing date 2022-05-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2022.903576
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Acetyl-CoA metabolic accumulation promotes hepatocellular carcinoma metastasis via enhancing CXCL1-dependent infiltration of tumor-associated neutrophils.

    Pan, Jun-Jie / Xie, Sun-Zhe / Zheng, Xin / Xu, Jian-Feng / Xu, Hao / Yin, Rui-Qi / Luo, Yun-Ling / Shen, Li / Chen, Zheng-Ru / Chen, Yi-Ran / Yu, Shi-Zhe / Lu, Lu / Zhu, Wen-Wei / Lu, Ming / Qin, Lun-Xiu

    Cancer letters

    2024  Volume 592, Page(s) 216903

    Abstract: High levels of acetyl-CoA are considered a key metabolic feature of metastatic cancers. However, the impacts of acetyl-CoA metabolic accumulation on cancer microenvironment remodeling are poorly understood. In this study, using human hepatocellular ... ...

    Abstract High levels of acetyl-CoA are considered a key metabolic feature of metastatic cancers. However, the impacts of acetyl-CoA metabolic accumulation on cancer microenvironment remodeling are poorly understood. In this study, using human hepatocellular carcinoma (HCC) tissues and orthotopic xenograft models, we found a close association between high acetyl-CoA levels in HCCs, increased infiltration of tumor-associated neutrophils (TANs) in the cancer microenvironment and HCC metastasis. Cytokine microarray and enzyme-linked immunosorbent assays (ELISA) revealed the crucial role of the chemokine (C-X-C motif) ligand 1(CXCL1). Mechanistically, acetyl-CoA accumulation induces H3 acetylation-dependent upregulation of CXCL1 gene expression. CXCL1 recruits TANs, leads to neutrophil extracellular traps (NETs) formation and promotes HCC metastasis. Collectively, our work linked the accumulation of acetyl-CoA in HCC cells and TANs infiltration, and revealed that the CXCL1-CXC receptor 2 (CXCR2)-TANs-NETs axis is a potential target for HCCs with high acetyl-CoA levels.
    Language English
    Publishing date 2024-04-24
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 195674-7
    ISSN 1872-7980 ; 0304-3835
    ISSN (online) 1872-7980
    ISSN 0304-3835
    DOI 10.1016/j.canlet.2024.216903
    Database MEDical Literature Analysis and Retrieval System OnLINE

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