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  1. Article ; Online: The association of serum vitamin D level and neonatal respiratory distress syndrome.

    Liu, Weili / Xu, Pingping

    Italian journal of pediatrics

    2023  Volume 49, Issue 1, Page(s) 16

    Abstract: Background: Neonatal respiratory distress syndrome (NRDS) is a critical disease in premature infants. Vitamin D plays an important role in promoting the development of fetal lung structure and the formation of pulmonary surfactants. This study aimed to ... ...

    Abstract Background: Neonatal respiratory distress syndrome (NRDS) is a critical disease in premature infants. Vitamin D plays an important role in promoting the development of fetal lung structure and the formation of pulmonary surfactants. This study aimed to investigate the correlation between the serum 25(OH)D
    Methods: This retrospective study recruited 82 preterm infants (gestational age 28-36 weeks) diagnosed with NRDS as the NRDS group, and 82 non-NRDS preterm infants as the control group, respectively. The diagnostic efficiency of 25(OH)D
    Results: Cord blood 25(OH)D
    Conclusion: 25(OH)D
    MeSH term(s) Infant ; Infant, Newborn ; Humans ; Infant, Premature ; Retrospective Studies ; Respiratory Distress Syndrome, Newborn/diagnosis ; Vitamin D ; Gestational Age
    Chemical Substances Vitamin D (1406-16-2)
    Language English
    Publishing date 2023-01-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2088556-8
    ISSN 1824-7288 ; 1720-8424
    ISSN (online) 1824-7288
    ISSN 1720-8424
    DOI 10.1186/s13052-023-01415-w
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1961: Show issues Location:
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  2. Article ; Online: IgG4-related disease with duodenal bulb involvement.

    Xu, Pingping / Cui, Yun / Sun, Danfeng

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2024  Volume 56, Issue 4, Page(s) 707–708

    MeSH term(s) Humans ; Immunoglobulin G4-Related Disease/diagnosis ; Duodenum ; Biopsy
    Language English
    Publishing date 2024-01-08
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2023.12.014
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  3. Article ; Online: Discussion on "Studio" Teaching of Art Design under the Background of Digital Innovative Design Technology

    Zhu Guangyao / Xu Pingping

    E3S Web of Conferences, Vol 236, p

    2021  Volume 05068

    Abstract: It is considered that only on the basis of studio teaching and by grasping the relevance of design specialty, forming a scalable and permeable platform, improving the teaching quality and enhancing the service consciousness of students' art design, can ... ...

    Abstract It is considered that only on the basis of studio teaching and by grasping the relevance of design specialty, forming a scalable and permeable platform, improving the teaching quality and enhancing the service consciousness of students' art design, can we better adapt to the current industry demand of art design education under the background of digital innovative design technology.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Cadmium-Induced Physiological Responses, Biosorption and Bioaccumulation in

    Xu, Pingping / Tu, Xiaojie / An, Zhengda / Mi, Wujuan / Wan, Dong / Bi, Yonghong / Song, Gaofei

    Toxics

    2024  Volume 12, Issue 4

    Abstract: Cadmium ion ( ... ...

    Abstract Cadmium ion (Cd
    Language English
    Publishing date 2024-03-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2733883-6
    ISSN 2305-6304 ; 2305-6304
    ISSN (online) 2305-6304
    ISSN 2305-6304
    DOI 10.3390/toxics12040262
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  5. Article ; Online: Molecular complexation properties of Cd

    Tu, Xiaojie / Xu, Pingping / Zhu, Yuxuan / Mi, Wujuan / Bi, Yonghong

    Ecotoxicology and environmental safety

    2023  Volume 263, Page(s) 115378

    Abstract: A detailed understanding the metals binding with algal organic matter (AOM) is essential to gain a deeper insight into the toxicity and migration of metals in algae cell. However, the molecular complexation mechanism of the metals binding with AOM ... ...

    Abstract A detailed understanding the metals binding with algal organic matter (AOM) is essential to gain a deeper insight into the toxicity and migration of metals in algae cell. However, the molecular complexation mechanism of the metals binding with AOM remains unclear. In this study, cadmium ion (Cd
    MeSH term(s) Cadmium/toxicity ; Scenedesmus ; Tryptophan ; Chlorophyceae ; Tyrosine
    Chemical Substances Cadmium (00BH33GNGH) ; Tryptophan (8DUH1N11BX) ; Tyrosine (42HK56048U)
    Language English
    Publishing date 2023-08-18
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 436536-7
    ISSN 1090-2414 ; 0147-6513
    ISSN (online) 1090-2414
    ISSN 0147-6513
    DOI 10.1016/j.ecoenv.2023.115378
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    Zs.A 1418: Show issues Location:
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  6. Article ; Online: A Retrospective Study from a Single Center to Identify Hematological Factors that Distinguish Between Patients with Colorectal Carcinoma and Colorectal Adenoma.

    Huang, Jun / Xu, Pingping / Chen, Youxiang

    Medical science monitor : international medical journal of experimental and clinical research

    2022  Volume 28, Page(s) e936745

    Abstract: BACKGROUND This retrospective study from a single center in China was conducted using data from medical records between 2012 and 2020, to identify hematological factors that distinguish between patients with colorectal carcinoma (CRC) and colorectal ... ...

    Abstract BACKGROUND This retrospective study from a single center in China was conducted using data from medical records between 2012 and 2020, to identify hematological factors that distinguish between patients with colorectal carcinoma (CRC) and colorectal adenoma. MATERIAL AND METHODS In this case-control study, 856 eligible patients were randomly divided into a training set (n=600) and a testing set (n=256). Routine blood parameters, blood coagulation, and liver and kidney function parameters were collected. Univariate and multivariate Cox regression analyses were used to explore diagnostic indicators. The values of the area under the curve and calibration curves were used to evaluate the model. RESULTS The study included 325 colorectal adenoma and 531 CRC patients. The prediction model for diagnosing CRC using hemoglobin-to-platelet ratio, fibrinogen-albumin ratio (FAR), albumin-globulin ratio (A/G), platelet-lymphocyte ratio, carcinoembryonic antigen (CEA), and thrombin time (TT) was developed on the basis of the patients grouped into the CRC and colorectal adenoma groups. The prediction model for diagnosing CRC stage was developed using prothrombin time (PT), TT, CEA, A/G, FAR, and HPR. The prediction model for diagnosing CRC grade was developed using PT, TT, A/G, plateletcrit, FAR, and HPR. The AUCs of the 3 prediction models were [0.848, 95% CI: (0.800-0.896)], [0.806, 95% CI: (0.775-0.836)], and [0.829, 95% CI: (0.797-0.860)] in the testing set. CONCLUSIONS Three diagnostic prediction models for early screening of CRC, stage of CRC, and grade of CRC were established through a panel of readily available hematological parameters, which could provide auxiliary tools for early screening of CRC.
    MeSH term(s) Adenoma/pathology ; Albumins ; Biomarkers, Tumor ; Carcinoembryonic Antigen ; Case-Control Studies ; Colorectal Neoplasms/pathology ; Humans ; Retrospective Studies
    Chemical Substances Albumins ; Biomarkers, Tumor ; Carcinoembryonic Antigen
    Language English
    Publishing date 2022-08-10
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1439041-3
    ISSN 1643-3750 ; 1234-1010
    ISSN (online) 1643-3750
    ISSN 1234-1010
    DOI 10.12659/MSM.936745
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    Zs.A 4924: Show issues Location:
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  7. Article: Nano Metal-Containing Photocatalysts for the Removal of Volatile Organic Compounds: Doping, Performance, and Mechanisms.

    Cheng, Rong / Xia, Jincheng / Wen, Junying / Xu, Pingping / Zheng, Xiang

    Nanomaterials (Basel, Switzerland)

    2022  Volume 12, Issue 8

    Abstract: Volatile organic compounds (VOCs) in indoor air are considered a major threat to human health and environmental safety. The development of applicable technologies for the removal of VOCs is urgently needed. Nowadays, photocatalytic oxidation (PCO) based ... ...

    Abstract Volatile organic compounds (VOCs) in indoor air are considered a major threat to human health and environmental safety. The development of applicable technologies for the removal of VOCs is urgently needed. Nowadays, photocatalytic oxidation (PCO) based on metal-containing photocatalysts has been regarded as a promising method. However, unmodified photocatalysts are generally limited in applications because of the narrow light response range and high recombination rate of photo-generated carriers. As a result, nano metal-containing photocatalysts doped with elements or other materials have attracted much attention from researchers and has developed over the past few decades. In addition, different doping types cause different levels of catalyst performance, and the mechanism for performance improving is also different. However, there are few reviews focusing on this aspect, which is really important for catalyst design and application. This work aims to give a comprehensive overview of nano metal-containing photocatalysts with different doping types for the removal of VOCs in an indoor environment. First, the undoped photocatalysts and the basic mechanism of PCO is introduced. Then, the application of metal doping, non-metal doping, co-doping, and other material doping in synthetic metal-containing photocatalysts are discussed and compared, respectively, and the synthesis methods, removal efficiency, and mechanisms are further investigated. Finally, a development trend for using nano metal-containing photocatalysts for the removal of VOCs in the future is proposed. This work provides a meaningful reference for selecting effective strategies to develop novel photocatalysts for the removal of VOCs in the future.
    Language English
    Publishing date 2022-04-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano12081335
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  8. Article ; Online: Multi-kingdom microbial signatures in excess body weight colorectal cancer based on global metagenomic analysis.

    Zhu, Xinyue / Xu, Pingping / Zhu, Ruixin / Gao, Wenxing / Yin, Wenjing / Lan, Ping / Zhu, Lixin / Jiao, Na

    Communications biology

    2024  Volume 7, Issue 1, Page(s) 24

    Abstract: Excess body weight (EBW) increases the risk of colorectal cancer (CRC) and is linked to lower colonoscopy compliance. Here, we extensively analyzed 981 metagenome samples from multiple cohorts to pinpoint the specific microbial signatures and their ... ...

    Abstract Excess body weight (EBW) increases the risk of colorectal cancer (CRC) and is linked to lower colonoscopy compliance. Here, we extensively analyzed 981 metagenome samples from multiple cohorts to pinpoint the specific microbial signatures and their potential capability distinguishing EBW patients with CRC. The gut microbiome displayed considerable variations between EBW and lean CRC. We identify 44 and 37 distinct multi-kingdom microbial species differentiating CRC and controls in EBW and lean populations, respectively. Unique bacterial-fungal associations are also observed between EBW-CRC and lean-CRC. Our analysis revealed specific microbial functions in EBW-CRC, including D-Arginine and D-ornithine metabolism, and lipopolysaccharide biosynthesis. The best-performing classifier for EBW-CRC, comprising 12 bacterial and three fungal species, achieved an AUROC of 0.90, which was robustly validated across three independent cohorts (AUROC = 0.96, 0.94, and 0.80). Pathogenic microbial species, Anaerobutyricum hallii, Clostridioides difficile and Fusobacterium nucleatum, are EBW-CRC specific signatures. This work unearths the specific multi-kingdom microbial signatures for EBW-CRC and lean CRC, which may contribute to precision diagnosis and treatment of CRC.
    MeSH term(s) Humans ; Metagenome ; Arginine ; Gastrointestinal Microbiome/genetics ; Weight Gain ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/genetics
    Chemical Substances Arginine (94ZLA3W45F)
    Language English
    Publishing date 2024-01-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-023-05714-0
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  9. Article ; Online: A bioinformatics analysis: ZFHX4 is associated with metastasis and poor survival in ovarian cancer.

    Zong, Shuai / Xu, Ping-Ping / Xu, Yin-Hai / Guo, Yi

    Journal of ovarian research

    2022  Volume 15, Issue 1, Page(s) 90

    Abstract: Background: Metastasis was the major cause of the high mortality in ovarian cancer. Although some mechanisms of metastasis in ovarian cancer were proposed, few have been targeted in the clinical practice. In the study, we aimed to identify novel genes ... ...

    Abstract Background: Metastasis was the major cause of the high mortality in ovarian cancer. Although some mechanisms of metastasis in ovarian cancer were proposed, few have been targeted in the clinical practice. In the study, we aimed to identify novel genes contributing to metastasis and poor clinical outcome in ovarian cancer from bioinformatics databases.
    Methods: Studies collecting matched primary tumors and metastases from ovarian cancer patients were searched in the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were screened by software R language. Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis for the DEGs were implemented by Metascape. Venn diagram was plotted to present overlapping DEGs. The associations between the overlapping DEGs and prognosis were tested by Cox proportional hazard regression model using a cohort of ovarian cancer patients from the TCGA database. Genes affecting patients' outcomes significantly were served as hub genes. The mechanisms of the hub genes in promoting ovarian cancer metastasis were then predicted by R software.
    Results: Two gene expression profiles (GSE30587 and GSE73168) met the inclusion criteria and were finally analyzed. A total of 259 genes were significantly differentially expressed in GSE30587, whereas 712 genes were in GSE73168. In GSE30587, DEGs were mainly involved in extracellular matrix (ECM) organization; For GSE73168, most of DEGs showed ion trans-membrane transport activity. There were 9 overlapping genes between the two datasets (RUNX2, FABP4, CLDN20, SVEP1, FAM169A, PGM5, ZFHX4, DCN and TAS2R50). ZFHX4 was proved to be an independent adverse prognostic factor for ovarian cancer patients (HR = 1.44, 95%CI: 1.13-1.83, p = 0.003). Mechanistically, ZFHX4 was positively significantly correlated with epithelial-mesenchymal transition (EMT) markers (r = 0.54, p = 2.59 × 10
    Conclusions: ZFHX4 might promote metastasis in ovarian cancer by regulating EMT and reprogramming ECM. For clinical applications, ZFHX4 was expected to be a prognostic biomarker for ovarian cancer metastasis.
    MeSH term(s) Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Carcinoma, Ovarian Epithelial/genetics ; Computational Biology ; Female ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Homeodomain Proteins/genetics ; Humans ; Ovarian Neoplasms/pathology ; Transcription Factors/genetics
    Chemical Substances Biomarkers, Tumor ; Homeodomain Proteins ; Transcription Factors ; ZFHX4 protein, human
    Language English
    Publishing date 2022-08-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2455679-8
    ISSN 1757-2215 ; 1757-2215
    ISSN (online) 1757-2215
    ISSN 1757-2215
    DOI 10.1186/s13048-022-01024-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Electrochemical Micro-Immunosensor of Cubic AuPt Dendritic Nanocrystals/Ti

    Feng, Wenpo / Xu, Pingping / Wang, Mei / Wang, Guidan / Li, Guangda / Jing, Aihua

    Micromachines

    2023  Volume 14, Issue 1

    Abstract: Exosomes are extracellular vesicles that exist in body circulation as intercellular message transmitters. Although the potential of tumor-derived exosomes for non-invasive cancer diagnosis is promising, the rapid detection and effective capture of ... ...

    Abstract Exosomes are extracellular vesicles that exist in body circulation as intercellular message transmitters. Although the potential of tumor-derived exosomes for non-invasive cancer diagnosis is promising, the rapid detection and effective capture of exosomes remains challenging. Herein, a portable electrochemical aptasensor of cubic AuPt dendritic nanocrystals (AuPt DNs)/Ti
    Language English
    Publishing date 2023-01-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi14010138
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