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  1. Book ; Thesis: Expression and functional analysis of the RasGAPs Rasal1, Rasal2 and Rasal3

    Xu, Rui

    2018  

    Author's details vorgelegt von Rui Xu
    Language English
    Size iii, 126 Seiten, Illustrationen, Diagramme, 21 cm
    Publishing place Marburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Philipps-Universität Marburg, 2018
    HBZ-ID HT019939218
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2019 D 80 order for loan Magazin

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  2. Article: Kazakh "free women" grit-Chinese Kazakh women's clothing image in the context of multicultural integration of silk road.

    Xu, Rui

    Frontiers in psychology

    2022  Volume 13, Page(s) 873815

    Abstract: In recent years, Chinese clothing cultural heritage and knowledge genealogy along the Silk Road have become the research headline attracting public attention. In particular, Kazakh clothing in Northwestern China has become the focus of today's ... ...

    Abstract In recent years, Chinese clothing cultural heritage and knowledge genealogy along the Silk Road have become the research headline attracting public attention. In particular, Kazakh clothing in Northwestern China has become the focus of today's traditional national culture. Kazakh, located at the intersection of the Silk Road, has an important position. The traditional clothing made by various social factors reflects the style and identity integration throughout history in cultures along the Silk Road, taking women's clothing as an example. Kazakh women are good at crafts, which is reflected in their strong grit. They gradually changed their role and traditional values, which has guided their social role. At the same time, it also reflects the awakening of Kazakh women's feminist consciousness to a large extent, and complies with Confucianism, along with the mainstream value of "advanced gender culture" of the world's outstanding civilization achievements. This paper summarizes the form, color, and patterns of Kazakh women's clothing by analyzing the garment, headdress, and footwear in Xinjiang Uygur Autonomous Region Museum, Aksai Kazakh National Museum, and Capital Museum of China. Through the analysis, this paper further probes into the multicultural integration between Kazakh and the regions along the Silk Road and interprets the idea represented by the forms, colors, and patterns in the clothing to promote the inheritance and development of traditional and regional cultures together with ethnic features along the Silk Road.
    Language English
    Publishing date 2022-07-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2022.873815
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Effects of maternal periodontal status on neonatal oral microbiota].

    Wang, Li / Xu, Rui

    Shanghai kou qiang yi xue = Shanghai journal of stomatology

    2023  Volume 32, Issue 3, Page(s) 318–322

    Abstract: Purpose: To explore whether oral hygiene and periodontal conditions of mothers had an impact on oral microbiota of newborns.: Methods: The oral health status of 48 mothers was examined and recorded. According to the mothers' periodontal status and ... ...

    Abstract Purpose: To explore whether oral hygiene and periodontal conditions of mothers had an impact on oral microbiota of newborns.
    Methods: The oral health status of 48 mothers was examined and recorded. According to the mothers' periodontal status and the age of infants, the subjects were divided into 4 groups: one-month-old periodontitis group (n=17), one-month-old healthy group (n=18), six-month-old periodontitis group (n=7) and six-month-old healthy group(n=6). Through high-throughput sequencing of saliva samples of infants aged one month and six months, the impact of mother's periodontal status on oral microbial diversity of infants of the same month was analyzed. SPSS 23.0 software package was used for data analysis.
    Results: In the two groups of one-month-old infants and the two groups of six-month-old infants, the oral microbial diversity in the healthy group was higher than that in the periodontitis group, but there was no significant difference. The species abundances of 12 species of Unclassified.Aggregatibacter, Unclassified. Ruminococcaceae, and Sp.Mycobacterium existed between the healthy group and the periodontitis group at the age of one month had significant difference. However, by the age of six months, only Elongata.Neisseria species was significantly different between the two groups.
    Conclusions: Different periodontal status of mothers has a certain influence on the microbial species diversity in the infant's oral cavity, and the difference in bacterial species abundance caused by this effect is more significant in one-month-old infants than in six-month-old infants.
    MeSH term(s) Infant ; Infant, Newborn ; Humans ; Periodontitis ; Bacteria/genetics ; Microbiota/genetics ; Periodontal Diseases
    Language Chinese
    Publishing date 2023-10-07
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 2269714-7
    ISSN 1006-7248
    ISSN 1006-7248
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6471: Show issues Location:
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  4. Article ; Online: Study on Transparent Basswood Dyed with Reactive Dyes and Its Properties.

    Zhao, Weiying / Rong, Yu / Xu, Rui / Wu, Yan

    ACS omega

    2024  Volume 9, Issue 5, Page(s) 5378–5385

    Abstract: In this work, sodium chlorite method was used to remove lignin in basswood and then the wood was dyed with reactive red X-3B dye. Finally, ultraviolet curing resins with a refractive index similar to cellulose were vacuum-impregnated into the wood to ... ...

    Abstract In this work, sodium chlorite method was used to remove lignin in basswood and then the wood was dyed with reactive red X-3B dye. Finally, ultraviolet curing resins with a refractive index similar to cellulose were vacuum-impregnated into the wood to obtain red transparent wood (RTW). Nowadays, transparent wood can be given color by various means and has a wide range of application prospects in the field of transparent wood decoration, but the color embodiment is relatively single. The aim was to develop a low-priced, easy-to-use process for the preparation of colored transparent wood with a sound color system. Transparent wood with colors will have more decorative and commercial value. The chemical composition, microscopic morphology, mechanical properties, and optical properties of dyed transparent wood were examined and analyzed. The results of the chemical composition analysis showed that after delignified treatment, the wood lost a large amount of lignin. After the dyeing treatment, the content of cellulose, hemicellulose, and lignin was slightly lost, and reactive dye groups appeared in the wood. Infrared spectra of transparent samples showed that the resin was successfully impregnated into the wood. The microscopic morphology analysis results showed that a small amount of dye molecules aggregated on the cell walls after dyeing treatment, and the resin was impregnated into the porous cellulose skeleton of the wood, filling the wood pores. The analysis of mechanical properties showed that the maximum tensile strength of dyed transparent wood reached 122.31 MPa, which was a higher resistance to tensile force compared to raw wood (with a maximum tensile strength of 97.56 MPa); the elongation at break reached 6.26%, which had better toughness compared to log (4.04%). Optical performance analysis showed that the transmittance of dyed transparent wood reached 81%, and dyeing did not change the transmittance of transparent wood. In addition, after undergoing yellowing resistance experiments, the color difference change of dyed transparent wood was much smaller than that of transparent wood.
    Language English
    Publishing date 2024-01-22
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c06372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Multi-omic analyses of m5C readers reveal their characteristics and immunotherapeutic proficiency.

    Xu, Rui / Wang, Yue / Kuang, Ye

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 1651

    Abstract: 5-methylcytosine (m5C) is a post-transcriptional RNA modification identified, m5C readers can specifically identify and bind to m5C. ALYREF and YBX1 as members of m5C readers that have garnered increasing attention in cancer research. However, ... ...

    Abstract 5-methylcytosine (m5C) is a post-transcriptional RNA modification identified, m5C readers can specifically identify and bind to m5C. ALYREF and YBX1 as members of m5C readers that have garnered increasing attention in cancer research. However, comprehensive analysis of their molecular functions across pancancer are lacking. Using the TCGA and GTEx databases, we investigated the expression levels and prognostic values of ALYREF and YBX1. Additionally, we assessed the tumor microenvironment, immune checkpoint-related genes, immunomodulators, Tumor Immune Dysfunction and Exclusion (TIDE) score and drug resistance of ALYREF and YBX1. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and Gene Set Enrichment Analysis (GSEA) analyses were performed to investigate the potential functions associated with m5C readers and coexpressed genes. Aberrant expression of ALYREF and YBX1 was observed and positively associated with prognosis in KIRP, LGG and LIHC. Furthermore, the expression levels of ALYREF and YBX1 were significantly correlated with immune infiltration of the tumor microenvironment and immune-related modulators. Last, our analysis revealed significant correlations between ALYREF, YBX1 and eIFs. Our study provides a substantial understanding of m5C readers and the intricate relationship between ALYREF, YBX1, eIFs, and mRNA dynamics. Through multidimensional analysis of immune infiltration and drug sensitivity/resistance in ALYREF and YBX1, we propose a possibility for combined modality therapy utilizing m5C readers.
    MeSH term(s) Multiomics ; 5-Methylcytosine ; Adjuvants, Immunologic ; Combined Modality Therapy ; Immunotherapy
    Chemical Substances 5-Methylcytosine (6R795CQT4H) ; Adjuvants, Immunologic
    Language English
    Publishing date 2024-01-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-52110-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Safety Review of Therapeutic Ultrasound for Spinal Cord Neuromodulation and Blood-Spinal Cord Barrier Opening.

    Xu, Rui / Treeby, Bradley E / Martin, Eleanor

    Ultrasound in medicine & biology

    2024  Volume 50, Issue 3, Page(s) 317–331

    Abstract: New focused ultrasound spinal cord applications have emerged, particularly those improving therapeutic agent delivery to the spinal cord via blood-spinal cord barrier opening and the neuromodulation of spinal cord tracts. One hurdle in the development of ...

    Abstract New focused ultrasound spinal cord applications have emerged, particularly those improving therapeutic agent delivery to the spinal cord via blood-spinal cord barrier opening and the neuromodulation of spinal cord tracts. One hurdle in the development of these applications is safety. It may be possible to use safety trends from seminal and subsequent works in focused ultrasound to guide the development of safety guidelines for spinal cord applications. We collated data from decades of pre-clinical studies and illustrate a clear relationship between damage, time-averaged spatial peak intensity and exposure duration. This relationship suggests a thermal mechanism underlies ultrasound-induced spinal cord damage. We developed minimum and mean thresholds for damage from these pre-clinical studies. When these thresholds were plotted against the parameters used in recent pre-clinical ultrasonic spinal cord neuromodulation studies, the majority of the neuromodulation studies were near or above the minimum threshold. This suggests that a thermal neuromodulatory effect may exist for ultrasonic spinal cord neuromodulation, and that the thermal dose must be carefully controlled to avoid damage to the spinal cord. By contrast, the intensity-exposure duration threshold had no predictive value when applied to blood-spinal cord barrier opening studies that employed injected contrast agents. Most blood-spinal cord barrier opening studies observed slight to severe damage, except for small animal studies that employed an active feedback control method to limit pressures based on measured bubble oscillation behavior. The development of new focused ultrasound spinal cord applications perhaps reflects the recent success in the development of focused ultrasound brain applications, and recent work has begun on the translation of these technologies from brain to spinal cord. However, a great deal of work remains to be done, particularly with respect to developing and accepting safety standards for these applications.
    MeSH term(s) Animals ; Blood-Brain Barrier/diagnostic imaging ; Brain ; Ultrasonic Therapy/methods ; Ultrasonography ; Spinal Cord
    Language English
    Publishing date 2024-01-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 186150-5
    ISSN 1879-291X ; 0301-5629
    ISSN (online) 1879-291X
    ISSN 0301-5629
    DOI 10.1016/j.ultrasmedbio.2023.11.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 963: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  7. Article ; Online: Corrigendum to 'Safety Review of Therapeutic Ultrasound for Spinal Cord Neuromodulation and Blood-Spinal Cord Barrier Opening' [Ultrasound in Med & Biol. 50 (2024) 317-331].

    Xu, Rui / Treeby, Bradley E / Martin, Eleanor

    Ultrasound in medicine & biology

    2024  

    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Published Erratum
    ZDB-ID 186150-5
    ISSN 1879-291X ; 0301-5629
    ISSN (online) 1879-291X
    ISSN 0301-5629
    DOI 10.1016/j.ultrasmedbio.2024.03.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 963: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Challenges and opportunities in oncology drug development and clinical research in China.

    Wang, Feng / Ruan, Dan-Yun / Xu, Rui-Hua

    Cell

    2024  Volume 187, Issue 7, Page(s) 1578–1583

    Abstract: As one of the world's most populous countries, China bears a heavy burden and a broad spectrum of cancers, including unique types, providing a unique environment for drug research and development. In recent years, China has leapt forward in oncology drug ...

    Abstract As one of the world's most populous countries, China bears a heavy burden and a broad spectrum of cancers, including unique types, providing a unique environment for drug research and development. In recent years, China has leapt forward in oncology drug development and clinical trials, presenting new opportunities and challenges.
    MeSH term(s) Humans ; China ; Drug Development ; Medical Oncology ; Neoplasms/drug therapy ; Antineoplastic Agents
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2024-03-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2024.02.040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MG 58: Show issues

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  9. Article ; Online: Lipidome isotope labelling of gut microbes (LILGM): A method of discovering endogenous microbial lipids.

    Chen, Li / Xu, Rui / Zhu, Jiangjiang

    Talanta

    2024  Volume 271, Page(s) 125730

    Abstract: Lipidomics analysis of gut microbiome has become critical in recent surge of extensive human disease studies that investigate microbiome contributions. However, challenges remain in comprehending the origins of thousands of lipid species produced by the ... ...

    Abstract Lipidomics analysis of gut microbiome has become critical in recent surge of extensive human disease studies that investigate microbiome contributions. However, challenges remain in comprehending the origins of thousands of lipid species produced by the diverse microbes. Here, we proposed the development and utilization of a liquid chromatography-mass spectrometry-based approach, named lipidome isotope labelling of gut microbes (LILGM), which enables confident detection and identification of endogenous gut microbial lipidome via
    MeSH term(s) Humans ; Lipids/chemistry ; Lipidomics ; Tandem Mass Spectrometry/methods ; Isotope Labeling/methods ; Gastrointestinal Microbiome ; Isotopes/analysis
    Chemical Substances Lipids ; Isotopes
    Language English
    Publishing date 2024-02-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2024.125730
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Laser-induced locally controllable craze-like microstructures for polymer white structural coloration.

    Feng, Jin / Xu, Rui / Huang, Jiameng / Zhou, Tao

    Materials horizons

    2024  

    Abstract: As a promising candidate for the inkless coloring method, white structural color has undergone widespread investigation because of its fascinating properties. Recently, various methods have been developed to prepare disordered micro/nanostructures to ... ...

    Abstract As a promising candidate for the inkless coloring method, white structural color has undergone widespread investigation because of its fascinating properties. Recently, various methods have been developed to prepare disordered micro/nanostructures to produce white structural color. However, complex and high-cost processing procedures severely restrict the efficient and large-scale preparation of disordered micro/nanostructures for achieving white structural color. Herein, we report an ingenious way to realize white structural color by laser-inducing craze-like microstructures in core-shell microfiber-based polymers. A microfiber with copper nanowires (CuNWs) as the core surrounded by a polyformaldehyde (POM) shell is prepared by a simple
    Language English
    Publishing date 2024-03-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2744250-0
    ISSN 2051-6355 ; 2051-6347
    ISSN (online) 2051-6355
    ISSN 2051-6347
    DOI 10.1039/d4mh00127c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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