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  1. Article ; Online: Structural and mechanical characterization of the hoof in Mongolian equids.

    Chen, Nuo / Yang, Xin / Xu, Shucai / Song, Jiafeng

    Micron (Oxford, England : 1993)

    2024  Volume 180, Page(s) 103609

    Abstract: In this paper, the microstructure and mechanical properties (including nanoindentation, tensile test, and compression test) of Mongolian horse hooves were investigated. Many tubules and Intermediate Filaments (IF) were distributed longitudinally in the ... ...

    Abstract In this paper, the microstructure and mechanical properties (including nanoindentation, tensile test, and compression test) of Mongolian horse hooves were investigated. Many tubules and Intermediate Filaments (IF) were distributed longitudinally in the hoof of Mongolian horses, which could better help the hoof cushioning. The hardness and modulus of the hoof wall of Mongolian horses varied at different water contents. The hardness and modulus decreased with the increase in water content. The modulus of elasticity of the hoof wall decreased from 16.3% to 25.4%, and the hardness decreased from 17.8% to 29.3% from 10% to 20% water content. At 20-30% water content, the horseshoe wall modulus decreased by 3.5%-4.8%, and the hardness reduced by 4.1%-7.3%. The results of the tensile and compression experiments showed that the compression properties of Mongolian horse hooves were better than their tensile properties; their longitudinal compression energy absorption was better than their transverse compression properties; and Young's modulus and yield strength of the hoof wall increased as the compression rate increased. Finally, comparing the experiments belonging to this paper with hooves from other papers, it was found that the hardness of the tubular region and the intertubular region of Mongolian horse hooves was 17.7% and 39.4% higher than that of the hooves from the current study, respectively. The microstructural features of Mongolian horse-like hooves with superior mechanical properties provide a promising inspiration for the bionic design of lightweight and high-strength composites in engineering.
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 207808-9
    ISSN 1878-4291 ; 0047-7206 ; 0968-4328
    ISSN (online) 1878-4291
    ISSN 0047-7206 ; 0968-4328
    DOI 10.1016/j.micron.2024.103609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Biomimetic Study of a Honeycomb Energy Absorption Structure Based on Straw Micro-Porous Structure.

    Xu, Shucai / Chen, Nuo / Qin, Haoyi / Zou, Meng / Song, Jiafeng

    Biomimetics (Basel, Switzerland)

    2024  Volume 9, Issue 1

    Abstract: In this paper, sorghum and reed, which possess light stem structures in nature, were selected as biomimetic prototypes. Based on their mechanical stability characteristics-the porous structure at the node feature and the porous feature in the outer skin- ...

    Abstract In this paper, sorghum and reed, which possess light stem structures in nature, were selected as biomimetic prototypes. Based on their mechanical stability characteristics-the porous structure at the node feature and the porous feature in the outer skin- biomimetic optimization design, simulation, and experimental research on both the traditional hexagonal structure and a hexagonal honeycomb structure were carried out. According to the two types of straw microcell and chamber structure characteristics, as well as the cellular energy absorption structure for the bionic optimization design, 22 honeycomb structures in 6 categories were considered, including a corrugated cell wall bionic design, a modular cell design, a reinforcement plate structure, and a self-similar structure, as well as a porous cell wall structure and gradient structures of variable wall thickness. Among them, HTPC-3 (a combined honeycomb structure), HSHT (a self-similar honeycomb structure), and HBCT-257 (a radial gradient variable wall thickness honeycomb structure) had the best performance: their energy absorption was 41.06%, 17.84%, and 83.59% higher than that of HHT (the traditional hexagonal honeycomb decoupling unit), respectively. Compared with HHT (a traditional hexagon honeycomb decoupling unit), the specific energy absorption was increased by 39.98%, 17.24%, and 26.61%, respectively. Verification test analysis revealed that the combined honeycomb structure performed the best and that its specific energy absorption was 22.82% higher than that of the traditional hexagonal structure.
    Language English
    Publishing date 2024-01-21
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2313-7673
    ISSN (online) 2313-7673
    DOI 10.3390/biomimetics9010060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Study on driver's active emergency response in dangerous traffic scenes based on driving simulator.

    Ma, Shuai / Xu, Shucai / Song, Jiafeng / Wang, Kejun / Qin, Haoyi / Wang, Ruixiang

    Traffic injury prevention

    2024  Volume 25, Issue 2, Page(s) 116–121

    Abstract: Objective: A driver's active emergency response in dangerous traffic scenes consists of two parts, including reaction behavior and physiological state. In dangerous traffic scenes, the driver's active emergency response has an important impact on human ... ...

    Abstract Objective: A driver's active emergency response in dangerous traffic scenes consists of two parts, including reaction behavior and physiological state. In dangerous traffic scenes, the driver's active emergency response has an important impact on human collision injury. Clarifying the driver's active emergency response is an important prerequisite for the study of human collision injury under nonstandard posture. Therefore, this study investigates the driver's active emergency response in different inevitable collision scenes using driving simulator.
    Methods: A driving simulator with a high-speed camera system and human physiological signal acquisition system was first built. Then, three typical vehicle dangerous collision scenes were developed, including frontal collision, side collision, and rear-end collision. Finally, twenty participants (15 males and 5 females) were recruited for a driving experiment, and their active emergency responses were recorded and analyzed.
    Results: All subjects would rotate the steering wheel to the left or right in the active emergency state, and the rotation of the hand would also cause the subject's upper body to tilt in the same direction. The maximum angle for male subjects to rotate the steering wheel was 59.98°, while for the female subjects, it was 44.28°. In addition, the maximum grip force between the male subjects and the steering wheel was 280.5 N, compared to 192.5 N for female subjects. Compared to the female participants, the male participants not only have a greater rotation angle and a greater grip force on the steering wheel, but also have greater pressure on the brake pedal, and the foot moves quickly from the accelerator pedal to the brake pedal and presses the brake pedal.
    Conclusions: Drivers have different active emergency responses to different vehicle collision scenes. Quantitative statistics of driver's active emergency response will have important guiding significance for the analysis of the impact of human active emergency response on human injury characteristics in subsequent vehicle collision experiments.
    MeSH term(s) Humans ; Male ; Female ; Automobile Driving ; Accidents, Traffic/prevention & control ; Reaction Time/physiology ; Lower Extremity/physiology ; Dangerous Behavior
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2089818-6
    ISSN 1538-957X ; 1538-9588
    ISSN (online) 1538-957X
    ISSN 1538-9588
    DOI 10.1080/15389588.2023.2282948
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: [Expression and Clinical Significance of Serum MiR-370 and MiR-203 in Patients with Acute Myeloid Leukemia].

    Ye, Li-Hua / Ma, Xiao / Xu, Shu-Cai

    Zhongguo shi yan xue ye xue za zhi

    2021  Volume 29, Issue 2, Page(s) 445–449

    Abstract: Objective: To investigate the expression of microRNA-370 (miR-370) and microRNA-203 (miR-203) in the serum of patients with acute myeloid leukemia(AML), and to analyze its clinical diagnosis and prognostic significance.: Methods: 57 patients with ... ...

    Abstract Objective: To investigate the expression of microRNA-370 (miR-370) and microRNA-203 (miR-203) in the serum of patients with acute myeloid leukemia(AML), and to analyze its clinical diagnosis and prognostic significance.
    Methods: 57 patients with acute myeloid leukemia were enrolled as experimental group, and 21 healthy people were enrolled as control group. The fasting venous blood of the personal in the two groups were collected. The expression of miR-370 and miR-203 of the personal in each groups were detected by real-time fluorescent quantitative PCR. The receiver operating characteristic (ROC) curve was plotted to detected the diagnostic values of serum miR-370, miR-203, and the Kaplan-Meier method was used to estimate the relationship between expression and overall survival of the patients.
    Results: Compared with healthy controls, serum miR-370 expression was significantly decreased in AML patients(P<0.05), and serum miR-203 expression was also significantly decreased (P<0.05). ROC curve analysis showed that the expression of serum miR-370 and miR-203 could be used to distinguish acute myeloid leukemia and healthy people. The area under the ROC curve of miR-370 was 0.909, and the sensitivity and specificity were 91.46% and 100.00%, respectively. The area under the ROC curve of miR-203 was 0.895, and the sensitivity and specificity were 83.45% and 89.71%, respectively. Serum levels of miR-370 and miR-203 were closely related to overall survival in AML patients.
    Conclusion: The expression of miR-370 and miR-203 is decreased in the serum of patients with AML and may be a new markers for the diagnosis and prognosis of AML.
    MeSH term(s) Biomarkers, Tumor ; Humans ; Kaplan-Meier Estimate ; Leukemia, Myeloid, Acute/genetics ; MicroRNAs ; Prognosis ; ROC Curve
    Chemical Substances Biomarkers, Tumor ; MIRN203 microRNA, human ; MIRN370 microRNA, human ; MicroRNAs
    Language Chinese
    Publishing date 2021-03-26
    Publishing country China
    Document type Journal Article
    ZDB-ID 2404306-0
    ISSN 1009-2137
    ISSN 1009-2137
    DOI 10.19746/j.cnki.issn.1009-2137.2021.02.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Research on Impact Resistance of Aluminum Alloy New Rotating Thin-Walled Structures.

    Xu, Shu-Cai / Chen, Nuo / Qin, Hao-Yi / Wang, Rui-Xiang / Yang, Xin / Song, Jia-Feng

    Biomimetics (Basel, Switzerland)

    2023  Volume 8, Issue 8

    Abstract: Honeycomb structures are widely used in the field of impact resistance and are constantly being developed and updated. In this paper, the design of three new aluminum alloy rotating thin-walled structures (NRTS) are examined. These structures combine ... ...

    Abstract Honeycomb structures are widely used in the field of impact resistance and are constantly being developed and updated. In this paper, the design of three new aluminum alloy rotating thin-walled structures (NRTS) are examined. These structures combine common concave structures and rotating, rigid-body structures. The purpose of this study is to solve the problem of the poor energy absorption capacity of rotating, rigid-body structure due to small deformation and to provide a reference for honeycomb mechanism designs. The Young's modulus, the critical velocity, and the platform stress of the NRTS structure are derived from theoretical analysis. The dynamic response of the NRTS structure at different impact velocities is investigated using finite element simulation software. The results show that the rotating, thin-walled recessed honeycomb (RTRH) increases the plateau stress by 124% and 51% as compared to rotating, thin-walled square tubes (RTSTs) and the re-entrant hexagonal structure (RH), respectively; the rotating, thin-walled quadruple-arc honeycomb structure (RTQH) increases the SEA by 21% and 20% as compared to the RTST and RH, respectively; and the rotating thin-walled double-arc honeycomb structure (RTDH) increases the CEF by 54% and 51% as compared to the RTST and RH, respectively. During the study, it was demonstrated that NTRS also exhibits good energy absorption capacity. Then, the effect of rotation angle on the energy absorption performance was analyzed. The cell and wall thickness of the NTRS structure were optimized according to the gradient theory. It was proved that the gradient optimized structure has better energy absorption performance as compared to the uniform structure.
    Language English
    Publishing date 2023-12-05
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2313-7673
    ISSN (online) 2313-7673
    DOI 10.3390/biomimetics8080590
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Predicting pathogenic genes for primary myelofibrosis based on a system‑network approach.

    Xu, Shu-Cai / Ning, Peng

    Molecular medicine reports

    2018  Volume 17, Issue 1, Page(s) 186–192

    Abstract: The aim of the present study was to predict pathogenic genes for primary myelofibrosis (PMF) using a system‑network approach by combining protein‑protein interaction (PPI) network and gene expression data with known pathogenic genes. PMF gene expression ... ...

    Abstract The aim of the present study was to predict pathogenic genes for primary myelofibrosis (PMF) using a system‑network approach by combining protein‑protein interaction (PPI) network and gene expression data with known pathogenic genes. PMF gene expression profiles, known pathogenic genes and protein‑protein interactions were obtained. Using these data, differentially expressed genes (DEGs) were identified between PMF and normal conditions using significance analysis of microarrays, and seed genes were determined based on the intersection of known pathogenic genes and the PMF gene expression profile. A new network was constructed using the seed genes and their adjacent DEGs within the PPI network. Subsequently, a pathogenic network was extracted from the new network, and contained genes that interacted with at least two seed genes, and the candidate pathogenic genes were predicted based on the cohesion with seed genes. Cluster analysis was performed to mine the pathogenic modules from the pathogenic network, and functional analysis was performed to identify the putative biological processes of the candidate pathogenic genes. Results from the present study identified 845 DEGs between PMF and normal conditions, and 45 seed genes in PMF were screened. Subsequently, a pathogenic network comprising 103 nodes and 265 interactions was constructed, and 4 pathogenic modules (modules A‑D) were mined from the pathogenic network. There were nine candidate pathogenic genes contained within Module A and four potential pathogenic genes, including E1A‑binding protein p300, RAS‑like proto‑oncogene A, von Willebrand factor and RAF‑1 proto‑oncogene, serine/threonine kinase, were identified that may be involved in the same biological process with the seed genes. This study predicted 10 candidate pathogenic genes and several signaling pathways that may be related to the pathogenesis of PMF using a system‑network approach. These predictions may shed light on the PMF pathogenesis and may provide guidelines for future experimental verification.
    MeSH term(s) Computational Biology/methods ; Gene Expression Profiling ; Gene Regulatory Networks ; Genetic Association Studies/methods ; Genetic Predisposition to Disease ; Humans ; Models, Biological ; Neural Networks (Computer) ; Primary Myelofibrosis/genetics ; Primary Myelofibrosis/metabolism ; Signal Transduction
    Language English
    Publishing date 2018-01
    Publishing country Greece
    Document type Journal Article
    ISSN 1791-3004
    ISSN (online) 1791-3004
    DOI 10.3892/mmr.2017.7847
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Parameter Optimization and Experiment of Soil Cleaning Device on Apple Seedling-Lifting Machine Based on Spatial RSSR Mechanism

    Huo, Peng / Li, Jiangping / Yang, Xing / Xu, Shucai / Fan, Xiaowen / Wang, Pengfei / Liu, Hongjie

    Applied engineering in agriculture. 2021, v. 37, no. 3

    2021  

    Abstract: To solve the problems of poor working conditions, incomplete root systems, and low seedling-lifting efficiencies of apple orchard seedling-lifting machines, a new type of shaking soil-cleaning device was proposed, in which a spatial four-bar linkage ( ... ...

    Abstract To solve the problems of poor working conditions, incomplete root systems, and low seedling-lifting efficiencies of apple orchard seedling-lifting machines, a new type of shaking soil-cleaning device was proposed, in which a spatial four-bar linkage (RSSR) was used instead of a traditional planar linkage. By means of the direction cosine matrix, the position and pose of the spatial four-bar mechanism of the device were analyzed, and the functional relationship was obtained. A fast Fourier transform (FFT) was used to synthesize a periodic function of the spatial four-bar linkage, a numerical atlas was established, and the dimensions were selected by means of fuzzy recognition. A genetic algorithm (GA) was used to optimize the identified parameters, and the optimized mechanisms was compared with the traditional planar linkage mechanism. The results showed that the maximum positive and negative errors of the first curve fitting groups were 0.43% and 0.67%, respectively, and those of the second curve fitting group were 0.79% and 0.50%, respectively, which met the operating and precision requirements. The structure of the new oscillating soil cleaning device is compact. Meanwhile, moderate lengths of the main roots, dense root hair, and complete root systems were achieved. The results showed that the taproots remained intact, and they were between 120 and 150 mm long. Due to the small sample size, the damage rate of the seedlings was zero, and the seedlings produced by the two models met the agronomic requirements. Thus, the requirements of agricultural operations are met by the optimized mechanism. This design concept can provide ideas for follow-up spatial RSSR four-bar mechanism design, and the optimized size parameters can provide a reference for the follow-up design and research of seedling and soil clearing devices.
    Keywords agriculture ; algorithms ; apples ; orchards ; root hairs ; sample size ; seedlings ; soil
    Language English
    Size p. 455-465.
    Publishing place American Society of Agricultural Engineers
    Document type Article
    ZDB-ID 54345-7
    ISSN 0883-8542
    ISSN 0883-8542
    DOI 10.13031/aea.14304
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Study on the structural features and geometric parameters affecting the axial mechanical properties of the primary feather rachis.

    Zhou, Jianfei / Zou, Meng / Xu, Shucai / Li, Xiujuan / Song, Jiafeng / Qi, Yingchun

    Microscopy research and technique

    2021  Volume 85, Issue 3, Page(s) 861–874

    Abstract: The seagull feather shaft is an important part of the feather, which provides a good mechanical support for the excellent flight performance of seagull, and has the characteristics of lightweight and high strength. In this paper, the microstructure of ... ...

    Abstract The seagull feather shaft is an important part of the feather, which provides a good mechanical support for the excellent flight performance of seagull, and has the characteristics of lightweight and high strength. In this paper, the microstructure of the seagull feather rachis was observed firstly. Then, based on the structure of feather rachis, combined with the cortex that plays the main load-bearing role, a model with the characteristics of the cortex was proposed and its finite element model was established. Through analyzing the simulation, the effect of section shape of cortex on mechanical properties of feathers under axial impact was revealed. And the conclusion that the section shape with groove structure and non-equal wall thickness could have different effects on mechanical properties was drawn. Then, parameterized cortical models were studied, including different impact velocities and different cortical heights, to reveal the differences in mechanical properties of cortical models.
    MeSH term(s) Animals ; Charadriiformes ; Feathers
    Language English
    Publishing date 2021-10-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099714-3
    ISSN 1097-0029 ; 1059-910X
    ISSN (online) 1097-0029
    ISSN 1059-910X
    DOI 10.1002/jemt.23955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Mechanical properties and failure deformation mechanisms of yak horn under quasi-static compression and dynamic impact.

    Liu, Shengfu / Xu, Shucai / Song, Jiafeng / Zhou, Jianfei / Xu, Lihan / Li, Xiujuan / Zou, Meng

    Journal of the mechanical behavior of biomedical materials

    2020  Volume 107, Page(s) 103753

    Abstract: In the natural environment, the horns of yak possess remarkable structural mechanical properties to protect the head from injury. In this paper, quasi-static compression and dynamic impact tests were conducted on yak horn in different regions under axial ...

    Abstract In the natural environment, the horns of yak possess remarkable structural mechanical properties to protect the head from injury. In this paper, quasi-static compression and dynamic impact tests were conducted on yak horn in different regions under axial and lateral conditions to evaluate mechanical properties such as elastic modulus, ultimate strength and energy absorption. Meanwhile, the failure deformation mechanism under both low and high strain rates is explored. Moreover, experimental analysis of the correlation among mechanical properties, sampling position, strain rate and loading direction was conducted. Fracture surface of horn was observed with the scanning electron microscope (SEM). Research data demonstrate that specific energy absorption and mechanical properties are correlated with sampling position. Under quasi-static compression and dynamic impact, clear anisotropy behavior of horn was observed, which is evidently reflected in the load-displacement curve. Mechanical properties such as elastic modulus and ultimate strength are different under quasi-static compression and dynamic impact. The failure mode of lamellar buckling and delamination existed in the axial failure process. Brittle fracture and extrusion densification occurred more frequently in the process of lateral failure.
    MeSH term(s) Animals ; Anisotropy ; Cattle ; Elastic Modulus ; Horns ; Pressure ; Stress, Mechanical
    Language English
    Publishing date 2020-04-02
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2378381-3
    ISSN 1878-0180 ; 1751-6161
    ISSN (online) 1878-0180
    ISSN 1751-6161
    DOI 10.1016/j.jmbbm.2020.103753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Bionic Design of the Bumper Beam Inspired by the Bending and Energy Absorption Characteristics of Bamboo.

    Zou, Meng / Song, Jiafeng / Xu, Shucai / Liu, Shengfu / Chang, Zhiyong

    Applied bionics and biomechanics

    2018  Volume 2018, Page(s) 8062321

    Abstract: This study conducted quasistatic three-point bending tests to investigate the effect of bamboo node on the energy absorption, bending, and deformation characteristics of bamboo. Results showed that the node had a reinforcing effect on the energy ... ...

    Abstract This study conducted quasistatic three-point bending tests to investigate the effect of bamboo node on the energy absorption, bending, and deformation characteristics of bamboo. Results showed that the node had a reinforcing effect on the energy absorption and bending strength of the bamboo culm subjected to bending load. The experimental results demonstrated that nodal samples (NS) significantly outperform internodal samples without node (INS). Under the three-point bending load, the main failure mode of bamboo is the fracture failure. The node also showed split and fracture prevention function obviously. Based on that, a series of bionic bumper beams were designed inspired by the bamboo node. The FEM results indicated that the performance of bionic bumpers was better than that of a normal bumper with regard to bending strength, energy absorption, and being lightweight. In particular, the bionic bumper beam has the best performance with regard to bending, energy absorption, and being lightweight compared with the normal bumper under pole impact. The characteristic of the bionic bumper beam is higher than that of the normal bumper beam by 12.3% for bending strength, 36.9% for EA, and 31.4% for SEA; moreover, there was a mass reduction of 4.9%, which still needs further optimization.
    Language English
    Publishing date 2018-12-02
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2179924-6
    ISSN 1754-2103 ; 1176-2322
    ISSN (online) 1754-2103
    ISSN 1176-2322
    DOI 10.1155/2018/8062321
    Database MEDical Literature Analysis and Retrieval System OnLINE

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