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Article ; Online: Building materials production process carbon emission analysis and optimization of Low-Carbon manufacturing

Shao Liangshan / Xu Wenfeng

E3S Web of Conferences, Vol 439, p

2023 Volume 02005

Abstract: In order to study the carbon emission characteristics of building materials production process, the material, energy consumption and carbon emission characteristics of building materials production process were analyzed, the carbon emission boundary ... ...

Abstract	In order to study the carbon emission characteristics of building materials production process, the material, energy consumption and carbon emission characteristics of building materials production process were analyzed, the carbon emission boundary conditions of building materials production process were proposed, and the carbon emission calculation model of building materials production process was established. Based on the data provided by a manufacturing company, we calculated and analyzed the carbon emissions of the building materials production process, identified the waste in this production line, and proposed an analysis method based on lean thinking to propose corresponding improvement measures from the production management level to address the waste problems. Reduce non-value-added carbon emissions caused by waste, thus improving the lean level of gear production lines and transforming to low carbon manufacturing.
Keywords	Environmental sciences ; GE1-350
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A comprehensive review of toxicity of coal fly ash and its leachate in the ecosystem.

Chen, Yi / Fan, Yingjie / Huang, Yu / Liao, Xiaoling / Xu, Wenfeng / Zhang, Tao

Ecotoxicology and environmental safety

2024 Volume 269, Page(s) 115905

Abstract: Coal fly ash (CFA), a byproduct of coal combustion, is a hazardous industrial solid waste. Its excessive global production, coupled with improper disposal practices, insufficient utilization and limited awareness of its inherent hazards, poses a ... ...

Abstract	Coal fly ash (CFA), a byproduct of coal combustion, is a hazardous industrial solid waste. Its excessive global production, coupled with improper disposal practices, insufficient utilization and limited awareness of its inherent hazards, poses a significant threat to both ecological environment and human health. Based on the physicochemical properties of CFA and its leachates, we elucidate the forms of CFA and potential pathways for its entry into the human body, as well as the leaching behavior, maximum tolerance and biological half-life of toxic elements present in CFA. Furthermore, we provide an overview of current strategies and methods for mitigating the leaching of these harmful elements from CFA. Moreover, we systemically summarize toxic effect of CFA on organisms across various tiers of complexity, analyze epidemiological findings concerning the human health implications resulting from CFA exposure, and delve into the biotoxicological mechanisms of CFA and its leachates at cellular and molecular levels. This review aims to enhance understanding of the potential toxicity of CFA, thereby promoting increased public awareness regarding the disposal and management of this industrial waste.
MeSH term(s)	Humans ; Coal Ash/analysis ; Ecosystem ; Coal ; Environment ; Industrial Waste/adverse effects
Chemical Substances	Coal Ash ; Coal ; Industrial Waste
Language	English
Publishing date	2024-01-02
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	436536-7
ISSN	1090-2414 ; 0147-6513
ISSN (online)	1090-2414
ISSN	0147-6513
DOI	10.1016/j.ecoenv.2023.115905
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Article ; Online: An endoplasmic reticulum stress-related signature featuring ASNS for predicting prognosis and immune landscape in prostate cancer.

Wu, Zhenyu / Wu, Zhenquan / Zeng, Jie / Liu, Yaxuan / Wang, Yue / Li, Huixin / Xia, Taolin / Liu, Weitao / Lin, Zhe / Xu, Wenfeng

Aging

2024 Volume 16, Issue 1, Page(s) 43–65

Abstract: Prostate cancer (PRAD) is one of the common malignant tumors of the urinary system. In order to predict the treatment results for PRAD patients, this study proposes to develop a risk profile based on endoplasmic reticulum stress (ERS). Based on the ... ...

Abstract	Prostate cancer (PRAD) is one of the common malignant tumors of the urinary system. In order to predict the treatment results for PRAD patients, this study proposes to develop a risk profile based on endoplasmic reticulum stress (ERS). Based on the Memorial Sloan-Kettering Cancer Center (MSKCC) cohort and the Gene Expression Omnibus database (GSE70769), we verified the predictive signature. Using a random survival forest analysis, prognostically significant ERS-related genes were found. An ERS-related risk score (ERscore) was created using multivariable Cox analysis. In addition, the biological functions, genetic mutations and immune landscape related to ERscore are also studied to reveal the underlying mechanisms related to ERS in PRAD. We further explored the ERscore-related mechanisms by profiling a single-cell RNA sequencing (scRNA-seq) dataset (GSE137829) and explored the oncogenic role of ASNS in PRAD through
MeSH term(s)	Humans ; Male ; Carcinogenesis ; Carcinogens ; Endoplasmic Reticulum Stress/genetics ; Prognosis ; Prostatic Neoplasms/genetics
Chemical Substances	Carcinogens ; ASNS protein, human (EC 6.3.5.4)
Language	English
Publishing date	2024-01-10
Publishing country	United States
Document type	Journal Article
ISSN	1945-4589
ISSN (online)	1945-4589
DOI	10.18632/aging.205280
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Article: Genome-wide identification of GATA transcription factors in tetraploid potato and expression analysis in differently colored potato flesh.

Zhang, Xia / Fan, Rong / Yu, Zhuo / Du, Xuerun / Yang, Xinyue / Wang, Huiting / Xu, Wenfeng / Yu, Xiaoxia

Frontiers in plant science

2024 Volume 15, Page(s) 1330559

Abstract: The GATA gene family belongs to a kind of transcriptional regulatory protein featuring a zinc finger motif, which is essential for plant growth and development. However, the identification of the GATA gene family in tetraploid potato is still not ... ...

Abstract	The GATA gene family belongs to a kind of transcriptional regulatory protein featuring a zinc finger motif, which is essential for plant growth and development. However, the identification of the GATA gene family in tetraploid potato is still not performed. In the present research, a total of 88
Language	English
Publishing date	2024-03-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2024.1330559
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Article: Compatibility of Niuhuang Jiedu Tablets Results in Attenuated Arsenic Bioaccumulation and Consequent Protection against Realgar-Induced Toxicity in Mice.

Xu, Wenfeng / Xu, Shuo / Kuang, Yongmei / He, Xiaorong / Jin, Pengfei

Evidence-based complementary and alternative medicine : eCAM

2022 Volume 2022, Page(s) 7406694

Abstract: Niuhuang Jiedu Tablets (NJT) is a popular over-the-counter traditional Chinese medicine (TCM) preparation. It is composed of realgar ( ... ...

Abstract	Niuhuang Jiedu Tablets (NJT) is a popular over-the-counter traditional Chinese medicine (TCM) preparation. It is composed of realgar (As
Language	English
Publishing date	2022-06-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2022/7406694
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Zs.A 5995: Show issues

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Article ; Online: A multi-omics study reveals the therapeutic effect of Linderae Radix water extract on irritable bowel syndrome (IBS-D).

Ouyang, Linqi / Liu, Tao / He, Yang / He, Yiran / Xu, Wenfeng / Deng, Guoyan / Deng, Guiming / Xiao, Xiaohe

Journal of ethnopharmacology

2024 Volume 328, Page(s) 118050

Abstract: Ethnopharmacological relevance: Linderae Radix (Lindera aggregata (Sims) Kosterm) is a traditional Chinese medicine known for its capability to regulate qi and relieve pain, particularly in the context of gastrointestinal disorders.: Aim of the study!# ...

Abstract	Ethnopharmacological relevance: Linderae Radix (Lindera aggregata (Sims) Kosterm) is a traditional Chinese medicine known for its capability to regulate qi and relieve pain, particularly in the context of gastrointestinal disorders. Aim of the study: While our previous research has demonstrated the efficacy of the Linderae Radix water extract (LRWE) in the treatment of diarrhea-predominant irritable bowel syndrome (IBS-D), the precise mechanisms remain elusive. This study aims to provide a comprehensive understanding of the therapeutic effects of LRWE on IBS-D through multi-omics techniques. Materials and methods: 16 S rRNA gene sequencing combined with LC-MS metabolomics was employed to investigate the effect of LRWE on the gut microbiota and metabolites of IBS-D rats. Spearman correlation analysis was performed on the gut microbiota and metabolites. Results: LRWE administration significantly ameliorated IBS-D rats' symptoms, including diarrhea, visceral hypersensitivity, and low-grade intestinal inflammation. Gut microbiota analysis revealed that LRWE influenced the diversity of the gut microbiota in IBS-D rats by significantly reducing the relative abundance of Patescibacteria and Candidatus Saccharimonas, while increasing the relative abundance of Jeotgalicoccus. Serum metabolomic analysis identified 16 differential metabolites, associated with LRWE's positive effects on IBS-D symptoms, focusing on glyoxylate and dicarboxylic acid metabolism, and cysteine and methionine metabolism. Spearman analysis demonstrated a strong correlation between cecal microbiota composition and serum metabolite levels. Conclusions: This study elucidates that LRWE plays a crucial role in the comprehensive therapeutic approach to IBS-D by restoring the relative abundance of gut microbiota and addressing the disturbed metabolism of endogenous biomarkers. The identified bacteria and metabolites present potential therapeutic targets for IBS-D.
MeSH term(s)	Rats ; Animals ; Irritable Bowel Syndrome/drug therapy ; Multiomics ; Diarrhea/drug therapy ; Diarrhea/microbiology ; Metabolomics/methods ; Biomarkers
Chemical Substances	Biomarkers
Language	English
Publishing date	2024-03-21
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2024.118050
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Zs.A 1494: Show issues

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Article ; Online: Iron(II)-Catalyzed Radical [3 + 2] Cyclization of

Lv, Shuo / Xu, Wen-Feng / Yang, Ting-You / Lan, Ming-Xing / Xiao, Ren-Xu / Mou, Xue-Qing / Chen, Yong-Zheng / Cui, Bao-Dong

Organic letters

2024 Volume 26, Issue 15, Page(s) 3151–3157

Abstract: A facile iron(II)-catalyzed radical [3 + 2] cyclization ... ...

Abstract	A facile iron(II)-catalyzed radical [3 + 2] cyclization of
Language	English
Publishing date	2024-04-02
Publishing country	United States
Document type	Journal Article
ISSN	1523-7052
ISSN (online)	1523-7052
DOI	10.1021/acs.orglett.4c00757
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Article ; Online: Phosphorus starvation response genes and function coupling: A mechanism to regulate phosphorus availability in a subtropical estuary.

Lin, Ling / Xiong, Jiangzhiqian / Yue, Tianchen / Xu, Wenfeng / Liu, Lihua / Wang, Feifei / Yang, Shengchang / Cao, Wenzhi

The Science of the total environment

2024 , Page(s) 172575

Abstract: Phosphorus (P) plays an important role in regulating primary production in estuarine environments. However, knowledge of the P-functional gene composition of microbial communities and the mechanisms of microbial adaptation to changes in available P in ... ...

Abstract	Phosphorus (P) plays an important role in regulating primary production in estuarine environments. However, knowledge of the P-functional gene composition of microbial communities and the mechanisms of microbial adaptation to changes in available P in estuaries remain limited. This study coupling 16 s rDNA and metagenomics sequencing was conducted to reveal the relationship between P cycling functional genes, microbial interactions, and P availability in the Jiulong River Estuary. The results showed that the relative abundance of P cycling functions genes was highest in winter, and lowest in summer. Spatially, the total relative abundance of P cycling functions genes was higher in the riverward than that in the seaward. P cycling functional microbial interactions and P cycling gene coupling were strongest in summer and in the seaward. Changes in both temperature and salinity had significant direct and indirect effects on P cycling function, and the influence of salinity on P cycling function was greater than that on the microbial community in the estuary. Salinity had significant direct negative effects on inorganic P-solubilization (IP), organic P-mineralization (OP), and P uptake and transport functions (PT). Whereas, salinity had a significant positive effect on P-starvation response regulation (PR) function. Thus, salinity and microbial communities regulate the soluble reactive phosphate concentrations in estuarine environments by strengthening internal coupling among P cycling functions, promoting PR function, and facilitating PT gene expression. PR is the most important predictors, PR, PT, and PR-PT together explained 38.56 % of the overall soluble reactive phosphorus (SRP) variation. Over 66 % of the explained SRP variations can be predicted by the PR, PT, and PR-PT functional genes. This finding improves the knowledge base of the microbial processes for P cycling and provides a foundation for eutrophication management strategies in the estuary.
Language	English
Publishing date	2024-04-17
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2024.172575
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Zs.A 949: Show issues

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Article: Epithelioid Subtype Gastrointestinal Stromal Tumors of Stomach in an Endoscopic Biopsy: A Potential Diagnostic Pitfall.

Xu, Wenfeng / Tang, Hao / Chen, Ying / Wang, Jiashuang / Chen, Zhongjiao / Xu, Yujuan / Guo, Deyu

OncoTargets and therapy

2023 Volume 16, Page(s) 1043–1049

Abstract: Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract with a broad morphological spectrum. Although epithelioid GISTs account for 20% of GISTs, their morphological features may pose a ... ...

Abstract	Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract with a broad morphological spectrum. Although epithelioid GISTs account for 20% of GISTs, their morphological features may pose a diagnostic pitfall for pathologists due to their morphological similarities to poorly differentiated adenocarcinoma and lymphoma. Case presentation: Herein, we report a 65-year-old male patient with gastric epithelioid GIST misdiagnosed as adenocarcinoma for four years. During this period, he was treated with chemotherapy combined with PD-L1 immunotherapy. The clinicians thought the treatments were effective. However, there was no significant change in tumor size. The patient's clinical symptoms did not improve significantly as well. Finally, an endoscopic biopsy was performed again and gastric epithelioid GIST was confirmed in our hospital through morphology, immunohistochemistry, and whole-genome sequencing. Conclusion: A broad morphological spectrum and diverse immunophenotypic changes of GISTs could represent a pitfall for pathologists. However, predisposed anatomical sites, morphology, and corresponding immunohistochemical markers are of great significance for the diagnosis of GISTs and the differential diagnosis from other diseases. On the other hand, clinicians should diagnose and comprehensively evaluate treatment effects based on the patient's clinical symptoms and relevant laboratory examinations, instead of over-reliance on pathological diagnosis.
Language	English
Publishing date	2023-12-12
Publishing country	New Zealand
Document type	Case Reports
ZDB-ID	2495130-4
ISSN	1178-6930
ISSN	1178-6930
DOI	10.2147/OTT.S444532
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Article: Secondary Sinonasal Collision Tumor of Papillary Squamous Cell Carcinoma and Small Cell Neuroendocrine Carcinoma After Nasopharyngeal Carcinoma Radiotherapy: A Case Report and Literature Review of Sinonasal Collision Carcinomas.

Tang, Hao / Wang, Lina / Xu, Wenfeng / Xu, Yujuan / Li, Xianyun / Guo, Deyu

OncoTargets and therapy

2023 Volume 16, Page(s) 91–97

Abstract: In the head and neck region, small cell neuroendocrine carcinoma (SmNEC) is extraordinary infrequent. Collision malignancy is also a rare entity in the nasal cavity, with merely sporadic 6 case reports on primary collision tumor associated with ... ...

Abstract	In the head and neck region, small cell neuroendocrine carcinoma (SmNEC) is extraordinary infrequent. Collision malignancy is also a rare entity in the nasal cavity, with merely sporadic 6 case reports on primary collision tumor associated with neuroendocrine carcinoma. The development of a secondary SmNEC within the previous radiation field had uncommonly been described, and there was no report on secondary sinonasal collision carcinoma with SmNEC component as a side reaction of nasopharyngeal carcinoma (NPC) radiotherapy. In light of the rarity of these neoplasms, we presented a case of a sinonasal collision carcinoma of papillary squamous cell carcinoma (PSCC) and SmNEC after NPC radiotherapy. To our knowledge, it may be the first case of a secondary coexistence of two malignancies synchronously in the nasal cavity after NPC treatment. Recognizing this peculiar kind of collision tumor associated SmNEC could promote our understanding of this entity and hence propose optimal treatment strategies.
Language	English
Publishing date	2023-02-11
Publishing country	New Zealand
Document type	Case Reports
ZDB-ID	2495130-4
ISSN	1178-6930
ISSN	1178-6930
DOI	10.2147/OTT.S396703
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