LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 6 of total 6

Search options

  1. Article ; Online: Yan Xiaoning’s experience in treating erythema nodule

    Xue-Yuan Yang / Xiao-Ning Yan

    Journal of Hainan Medical University, Vol 26, Iss 18, Pp 61-

    2020  Volume 64

    Abstract: Erythema tuberculum is a common disease in dermatology and difficult to treat. Chang an cheng's skin under the successive generations of the successor, unique, unique experience. Yan xiaoning summarized the etiology and pathogenesis of nodular erythema ... ...

    Abstract Erythema tuberculum is a common disease in dermatology and difficult to treat. Chang an cheng's skin under the successive generations of the successor, unique, unique experience. Yan xiaoning summarized the etiology and pathogenesis of nodular erythema as heat and humidity toxicity, and divided the syndrome differentiation into two syndromes: wind and heat toxicity containing moisture and heat. The prescription drug emphasizes in the overall concept of the foundation, both inside and outside treatment, treatment of the need to reconcile, both the spleen and stomach for the specimens. In this paper, Professor Yan Xiaoning's experience in the treatment of erythema nodule is summarized, and case 1 is attached as evidence
    Keywords yan xiaoning ; erythema nodosum ; etiology and pathogenesis ; characteristics ; experience ; Medicine ; R
    Language English
    Publishing date 2020-09-01T00:00:00Z
    Publisher Editorial Board of Journal of Hainan Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Meta-analysis of clinical effect of clearing heat and cooling blood on psoriasis and its effect on inflammatory cytokines

    Xue-Yuan Yang / Xiao-Ning Yan

    Journal of Hainan Medical University, Vol 26, Iss 19, Pp 53-

    2020  Volume 60

    Abstract: Objective: To evaluate the effect of Qingreliangxue method compared with Acitretin Capsules on clinical efficacy of psoriasis and serum inflammatory cytokines. Methods:The computer searches databases such as CNKI, Wanfang, VIP, PubMed, Embase and ... ...

    Abstract Objective: To evaluate the effect of Qingreliangxue method compared with Acitretin Capsules on clinical efficacy of psoriasis and serum inflammatory cytokines. Methods:The computer searches databases such as CNKI, Wanfang, VIP, PubMed, Embase and Cochrane Library. The search time is from the time the library is built until December 2019. According to the criteria for screening and selection of studies, extract data, use risk assessment tools for quality evaluation, and use Revman 5.3 software to perform meta-analysis on the outcome indicators of the included studis. Results: Finally, 20 studies were included, with a total of 1592 patients. The analysis results showed that the total effective rate (OR=3.70, 95%CI[2.58,5.30], P ＜0.00001) and cure rate (OR=2.40, 95%CI[1.86,3.10], P＜0.00001), PASI score (OR=-2.65, 95%CI[-3.60,-1.70], P＜0.00001), serum inflammatory cytokines（OR=-8.84，95%CI[- 10.52,-7.16], P＜0.00001）, adverse reactions (OR=0.25, 95%CI[0.11,0.57], P=0.001) are superior to Acitretin Capsules. Statistics of the top 10 Chinese medicines in clinical used frequency are, in order, habitat, red peony root, paeonol, honeysuckle, comfrey, soil tuckahoe, salvia miltiorrhiza, buffalo horn, heliotrope, angelica. Conclusion: Based on the current evidence, the treatment of psoriasis with clearing heat and cooling blood as the mainstay of Chinese medicine alone or in combination with Acitretin Capsules can better improve the efficacy, and its mechanism may be related to reducing inflammation. Due to the limitation of the included literature, this conclusion needs to be further verified.
    Keywords psoriasis ; removing pathogenic heat from blood ; acitretin capsules ; inflammatory cytokines ; curative effect ; meta-analysis ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher Editorial Board of Journal of Hainan Medical University
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Knockdown of CD146 promotes endothelial-to-mesenchymal transition via Wnt/β-catenin pathway.

    Zhao-Yu Zhang / Chao Zhai / Xue-Yuan Yang / Hai-Bing Li / Li-Ling Wu / Li Li

    PLoS ONE, Vol 17, Iss 8, p e

    2022  Volume 0273542

    Abstract: Purpose Cardiac fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) proteins and leads to the maladaptive changes in myocardium. Endothelial cells (ECs) undergoing mesenchymal transition contributes to the occurrence and ... ...

    Abstract Purpose Cardiac fibrosis is characterized by the excessive deposition of extracellular matrix (ECM) proteins and leads to the maladaptive changes in myocardium. Endothelial cells (ECs) undergoing mesenchymal transition contributes to the occurrence and development of cardiac fibrosis. CD146 is an adhesion molecule highly expressed in ECs. The present study was performed to explore the role of CD146 in modulating endothelial to mesenchymal transition (EndMT). Methods C57BL/6 mice were subjected to subcutaneous implantation of osmotic minipump infused with angiotensin II (Ang Ⅱ). Adenovirus carrying CD146 short hairpin RNA (shRNA) or CD146 encoding sequence were infected into cultured human umbilical vein endothelial cells (HUVECs) followed by stimulation with Ang II or transforming growth factor-β1 (TGF-β1). Differentially expressed genes were revealed by RNA-sequencing (RNA-Seq) analysis. Gene expression was measured by quantitative real-time PCR, and protein expression and distribution were determined by Western blot and immunofluorescence staining, respectively. Results CD146 was predominantly expressed by ECs in normal mouse hearts. CD146 was upregulated in ECs but not fibroblasts and myocytes in hearts of Ang II-infused mice and in HUVECs stimulated with Ang Ⅱ. RNA-Seq analysis revealed the differentially expressed genes related to EndMT and Wnt/β-catenin signaling pathway. CD146 knockdown and overexpression facilitated and attenuated, respectively, EndMT induced by Ang II or TGF-β1. CD146 knockdown upregulated Wnt pathway-related genes including Wnt4, LEF1, HNF4A, FOXA1, SOX6, and CCND3, and increased the protein level and nuclear translocation of β-catenin. Conclusions Knockdown of CD146 exerts promotional effects on EndMT via activating Wnt/β-catenin pathway and the upregulation of CD146 might play a protective role against EndMT and cardiac fibrosis.
    Keywords Medicine ; R ; Science ; Q
    Subject code 570
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article: Multiple response optimization for high efficiency energy saving treatment of rhodamine B wastewater in a three-dimensional electrochemical reactor

    Ji, Jing / Juan Xu / Xiu-yan Li / Xue-yuan Yang / Yang Liu

    Journal of environmental management. 2018 July 15, v. 218

    2018  

    Abstract: The removal of high-concentration rhodamine B (RhB) wastewater was investigated in a three-dimensional electrochemical reactor (3DER) packed with granular activated carbon (GAC) particle electrodes. Response surface methodology (RSM) coupled with grey ... ...

    Abstract The removal of high-concentration rhodamine B (RhB) wastewater was investigated in a three-dimensional electrochemical reactor (3DER) packed with granular activated carbon (GAC) particle electrodes. Response surface methodology (RSM) coupled with grey relational analysis (GRA) was used to evaluate the effects of voltage, initial pH, aeration rate and NaCl dosage on RhB removal and energy consumption of the 3DER. The optimal conditions were determined as voltage 7.25 V, pH 5.99, aeration rate 151.13 mL/min, and NaCl concentration 0.11 mol/L. After 30 min electrolysis, COD removal rate could arrive at 60.13% with an extremely low energy consumption of 6.22 kWh/kg COD. The voltage and NaCl were demonstrated to be the most significant factors affecting the COD removal and energy consumption of 3DER. The intermediates generated during the treatment process were identified and the possible degradation pathway of RhB was proposed. It is worth noting that 3DER also showed an excellent performance in total nitrogen (TN) removal under the optimal condition. The activated chlorine generated from chloride had great contributions to eliminate carbon and nitrogen of RhB wastewater. The treatment effluent had a good biodegradability, which was suitable for subsequent biological treatment.
    Keywords activated carbon ; aeration ; biodegradability ; biological treatment ; chemical oxygen demand ; chlorine ; electric potential ; electrochemistry ; electrodes ; electrolysis ; energy conservation ; nitrogen ; pH ; response surface methodology ; rhodamines ; sodium chloride ; total nitrogen ; wastewater
    Language English
    Dates of publication 2018-0715
    Size p. 300-308.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2018.04.071
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 7556: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article ; Online: Enhanced denitrification by nano ɑ-Fe2O3 induced self-assembled hybrid biofilm on particle electrodes of three-dimensional biofilm electrode reactors

    Si-yuan Wang / Xue-yuan Yang / Hui-shan Meng / Yan-chen Zhang / Xiu-yan Li / Juan Xu

    Environment International, Vol 125, Iss , Pp 142-

    2019  Volume 151

    Abstract: Three-dimensional biofilm electrode reactors (3D-BERs) represent a novel technology for wastewater denitrification. Formation of mature electroactive biofilm on particle electrodes is crucial to realize successful denitrification in 3D-BERs. However, ... ...

    Abstract Three-dimensional biofilm electrode reactors (3D-BERs) represent a novel technology for wastewater denitrification. Formation of mature electroactive biofilm on particle electrodes is crucial to realize successful denitrification in 3D-BERs. However, long start-up time and low electroactivity of the biofilm formed on particle electrodes limit the further application of 3D-BERs in wastewater treatment. In this work, self-assembled hybrid biofilms (SAHB) was cultivated on granular activate carbon particle electrodes of the 3D-BER by assembling nano ɑ-Fe2O3 into the biofilm. ɑ-Fe2O3 was selected due to its high affinity to bacterial outer-membrane cytochromes, an important mediator for microbial electron transfer. SAHB formed on particle electrodes were characterized and the denitrification performance of 3D-BERs was also investigated. Results indicate that nano ɑ-Fe2O3 plays positive roles in the start-up of 3D-BER, which captures more microbes into SAHB and constructs thick biofilm on particle electrodes. Special microorganisms with denitrification function related with genera of Hydrogenophaga and Opitutus are distinctively enriched in SAHB. Nano ɑ-Fe2O3 induced SAHB exhibit superior denitrification performance compared to natural biofilm. The average denitrification rate increases from 0.62 mg total nitrogen/L/h for natural biofilm to 1.73 mg total nitrogen/L/h for SAHB, mainly ascribed to accelerated nitrites reduction. Our work provides new technical solution to enhance nitrates removal in 3D-BERs and brings deep insights into application of bio-electrochemical system in wastewater treatment. Keywords: Hydrogen autotrophic denitrification, Nano ɑ-Fe2O3, Self-assembled hybrid biofilm (SAHB), Three-dimensional biofilm electrode reactors (3D-BERs)
    Keywords Environmental sciences ; GE1-350
    Subject code 620
    Language English
    Publishing date 2019-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article: Insights into the interactions between triclosan (TCS) and extracellular polymeric substance (EPS) of activated sludge

    Yan, Zi-run / Guo-ping Sheng / Hui-shan Meng / Juan Xu / Xiu-yan Li / Xue-yuan Yang / Yu-ying Zhu

    Journal of environmental management. 2019 Feb. 15, v. 232

    2019  

    Abstract: Triclosan (TCS) contaminant has aroused wide concerns due to the high risk of converting into toxic dioxin in aquatic environments. During the wastewater treatment process, considerable amounts of TCS are accumulated in activated sludge but the ... ...

    Abstract Triclosan (TCS) contaminant has aroused wide concerns due to the high risk of converting into toxic dioxin in aquatic environments. During the wastewater treatment process, considerable amounts of TCS are accumulated in activated sludge but the mechanisms are still unclear. Especially, roles of extracellular polymeric substances (EPS), the main components of activated sludge, in TCS removal have never been addressed. In this work, the binding properties of loosely-bound EPS (LB-EPS) and tightly-bound EPS (TB-EPS) of activated sludge to TCS are investigated by fluorescence quenching approach. The influences of aquatic conditions including solution pH, ionic strength and temperature on the interactions between EPS and TCS are explored. Possible interaction mechanisms are discussed as well as the corresponding environmental implication. Results indicate that binding processes of EPS to TCS are exothermic mainly driven by the enthalpy changes. The proteins components in EPS dominate the interactions between EPS and TCS by hydrogen bond and hydrophobic interaction. The binding strength could be improved under the condition of weak alkaline and relative high ionic strength. Generally, LB-EPS exhibit stronger binding ability to TCS than TB-EPS under neutral environment, playing more crucial roles in the binding process. This work highlights the important contributions of EPS to TCS removal, that is beneficial to comprehensively understand the migration of TCS in activated sludge system.
    Keywords activated sludge ; aquatic environment ; binding capacity ; dioxins ; enthalpy ; fluorescence ; heat production ; hydrogen bonding ; hydrophobic bonding ; ionic strength ; pH ; proteins ; risk ; temperature ; toxicity ; triclosan ; wastewater treatment
    Language English
    Dates of publication 2019-0215
    Size p. 219-225.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2018.11.059
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 7556: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top