LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 6462

Search options

  1. Article ; Online: How I use ChatGPT responsibly in my teaching.

    Yang, Hong

    Nature

    2023  

    Language English
    Publishing date 2023-04-12
    Publishing country England
    Document type News
    ZDB-ID 120714-3
    ISSN 1476-4687 ; 0028-0836
    ISSN (online) 1476-4687
    ISSN 0028-0836
    DOI 10.1038/d41586-023-01026-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 26: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 9: Show issues
    Zs.MO 244: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Global dynamics of a diffusive phytoplankton-zooplankton model with toxic substances effect and delay.

    Yang, Hong

    Mathematical biosciences and engineering : MBE

    2022  Volume 19, Issue 7, Page(s) 6712–6730

    Abstract: This paper examines a diffusive toxic-producing plankton system with delay. We first show the global attractivity of the positive equilibrium of the system without time-delay. We further consider the effect of delay on asymptotic behavior of the positive ...

    Abstract This paper examines a diffusive toxic-producing plankton system with delay. We first show the global attractivity of the positive equilibrium of the system without time-delay. We further consider the effect of delay on asymptotic behavior of the positive equilibrium: when the system undergoes Hopf bifurcation at some points of delay by the normal form and center manifold theory for partial functional differential equations. Global existence of periodic solutions is established by applying the global Hopf bifurcation theory.
    MeSH term(s) Animals ; Models, Biological ; Phytoplankton ; Zooplankton
    Language English
    Publishing date 2022-06-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2265126-3
    ISSN 1551-0018 ; 1551-0018
    ISSN (online) 1551-0018
    ISSN 1551-0018
    DOI 10.3934/mbe.2022316
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Silencing of Long Non-coding RNA H19 Alleviates Lipopolysaccharide (LPS)-induced Apoptosis and Inflammation Injury by Regulating miR-140-5p/TLR4 Axis in Cell Models of Pneumonia.

    Yang, Hong

    Current molecular medicine

    2022  Volume 23, Issue 3, Page(s) 275–284

    Abstract: Objective: Mounting studies have clarified the link between long non-coding RNAs (lncRNAs) and pneumonia. This research aims to probe the function and regulatory mechanism of lncRNA H19 in lipopolysaccharide (LPS)-induced cell models of pneumonia.: ... ...

    Abstract Objective: Mounting studies have clarified the link between long non-coding RNAs (lncRNAs) and pneumonia. This research aims to probe the function and regulatory mechanism of lncRNA H19 in lipopolysaccharide (LPS)-induced cell models of pneumonia.
    Methods: WI-38 cells were exposed to LPS for 12 h to mimic cell models of pneumonia. The relative expression of H19, miR-140-5p, and toll-like receptor 4 (TLR4) were detected by quantitative real-time polymerase chain reaction (qRT-PCR). The cell viability was detected by MTT assay. The protein expression of apoptosis-associated proteins (Bax and Bcl-2) and TLR4 were determined by western blot. Moreover, the content of interleukin (IL)-6, IL-1β, and tumor necrosis factor (TNF)-α were measured by enzyme-linked immunosorbent assay (ELISA). The target relationship between miR- 140-5p and H19/ TLR4 was confirmed by Dual luciferase reporter (DLR) assay.
    Results: LncRNA H19 and TLR4 were up-regulated, while miR-140-5p was downregulated in peripheral blood of patients with pneumonia and LPS-treated WI-38 cells compared with their controls. Silencing of H19 or miR-140-5p mimics facilitated cell viability, whereas repressed apoptosis and reduced content of TNF-α, IL-6, and IL-1β in LPS-induced WI-38 cells. H19 targeted miR-140-5p and it inversely regulated miR-140- 5p expression. MiR-140-5p targeted TLR4 and it inversely regulated TLR4 expression. H19 positively regulated TLR4 expression. Moreover, inhibition of miR-140-5p or overexpression of TLR4 reversed the effects of H19 silencing on cell viability, inflammation, and apoptosis in LPS-induced WI-38 cells.
    Conclusion: Silencing of H19 inhibited apoptosis and inflammation by miR-140- 5p/TLR4 pathway in LPS-induced WI-38 cells.
    MeSH term(s) Humans ; Apoptosis/genetics ; Inflammation/genetics ; Interleukin-6/genetics ; Lipopolysaccharides/toxicity ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Pneumonia/genetics ; Pneumonia/metabolism ; RNA, Long Noncoding/genetics ; Toll-Like Receptor 4/genetics ; Toll-Like Receptor 4/metabolism ; Tumor Necrosis Factor-alpha/genetics
    Chemical Substances Interleukin-6 ; Lipopolysaccharides ; MicroRNAs ; Mirn140 microRNA, human ; RNA, Long Noncoding ; TLR4 protein, human ; Toll-Like Receptor 4 ; Tumor Necrosis Factor-alpha ; H19 long non-coding RNA
    Language English
    Publishing date 2022-04-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2064873-X
    ISSN 1875-5666 ; 1566-5240
    ISSN (online) 1875-5666
    ISSN 1566-5240
    DOI 10.2174/1566524022666220407100949
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5580: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Giant accessory hepatic lobe accompanied by inflammatory pseudotumor.

    Yang, Hong / Lai, Binglin

    Hepatobiliary surgery and nutrition

    2024  Volume 13, Issue 1, Page(s) 194–195

    Language English
    Publishing date 2024-01-12
    Publishing country China (Republic : 1949- )
    Document type Case Reports
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-23-570
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Inflammatory myofibroblastoma mimicking cavernous hemangioma in the liver.

    Yang, Hong / Lai, Binglin

    Liver international : official journal of the International Association for the Study of the Liver

    2024  Volume 44, Issue 5, Page(s) 1265–1266

    Abstract: A 37-year-old female patient was admitted to the hospital with a large liver mass, diagnosed as hepatic inflammatory myofibroblastic tumour (HIMT), characterized by unique radiographic features and predominantly occurring in adults. HIMT consists of ... ...

    Abstract A 37-year-old female patient was admitted to the hospital with a large liver mass, diagnosed as hepatic inflammatory myofibroblastic tumour (HIMT), characterized by unique radiographic features and predominantly occurring in adults. HIMT consists of myofibroblast spindle cells infiltrated by plasma cells and/or lymphocytes, with an unclear aetiology linked to factors like infection and immune response. Treatment typically involves surgical resection, with chemotherapy or targeted therapy options for cases of incomplete resection or metastasis, emphasizing the need for precise diagnosis and tailored treatment strategies.
    MeSH term(s) Adult ; Female ; Humans ; Diagnosis, Differential ; Hemangioma, Cavernous/diagnosis ; Hemangioma, Cavernous/pathology ; Neoplasms, Muscle Tissue/diagnosis ; Neoplasms, Muscle Tissue/surgery ; Liver Neoplasms/pathology
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2102783-3
    ISSN 1478-3231 ; 1478-3223
    ISSN (online) 1478-3231
    ISSN 1478-3223
    DOI 10.1111/liv.15884
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1632: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Epidemiological research, burden, and clinical advances of inflammatory bowel disease in China.

    Yang, Hong / Qian, Jiaming

    Chinese medical journal

    2024  Volume 137, Issue 9, Page(s) 1009–1011

    MeSH term(s) Humans ; China/epidemiology ; Inflammatory Bowel Diseases/epidemiology
    Language English
    Publishing date 2024-03-28
    Publishing country China
    Document type Editorial
    ZDB-ID 127089-8
    ISSN 2542-5641 ; 0366-6999 ; 1002-0187
    ISSN (online) 2542-5641
    ISSN 0366-6999 ; 1002-0187
    DOI 10.1097/CM9.0000000000003064
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 1207: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Ua VI Zs.425: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Interpretation of Guidance for the Design and Implementation of Drug Clinical Studies

    BAI Xiaoyin / YANG Hong

    Xiehe Yixue Zazhi, Vol 14, Iss 1, Pp 81-

    Based on E8 (R1): General Considerations for Clinical Trials

    2023  Volume 85

    Abstract: As clinical research and drug development in China continue to advance, greater attention has been paid to the value of clinical research guidelines. The first revision of the original E8 recommendations (R1), 'General Considerations for Clinical ... ...

    Abstract As clinical research and drug development in China continue to advance, greater attention has been paid to the value of clinical research guidelines. The first revision of the original E8 recommendations (R1), 'General Considerations for Clinical Research' was made by the International Council for Harmonization in October 2021. Our National Medical Products Administration has recently opted to implement the rules beginning from July 2023. In order to provide useful references for improved design and execution of drug clinical studies in China, this paper primarily interprets the fundamental background and revision of E8 (R1) from the perspective of clinical workers. It also analyzes and discusses the application of the current clinical study guidelines in China.
    Keywords drug research and development ; clinical research ; guideline ; study design ; interpretation ; Medicine ; R
    Subject code 610
    Language Chinese
    Publishing date 2023-01-01T00:00:00Z
    Publisher Editorial Office of Medical Journal of Peking Union Medical College Hospital
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Book ; Online: Sketch2CADScript

    Yang, Hong-Bin

    3D Scene Reconstruction from 2D Sketch using Visual Transformer and Rhino Grasshopper

    2023  

    Abstract: Existing 3D model reconstruction methods typically produce outputs in the form of voxels, point clouds, or meshes. However, each of these approaches has its limitations and may not be suitable for every scenario. For instance, the resulting model may ... ...

    Abstract Existing 3D model reconstruction methods typically produce outputs in the form of voxels, point clouds, or meshes. However, each of these approaches has its limitations and may not be suitable for every scenario. For instance, the resulting model may exhibit a rough surface and distorted structure, making manual editing and post-processing challenging for humans. In this paper, we introduce a novel 3D reconstruction method designed to address these issues. We trained a visual transformer to predict a "scene descriptor" from a single wire-frame image. This descriptor encompasses crucial information, including object types and parameters such as position, rotation, and size. With the predicted parameters, a 3D scene can be reconstructed using 3D modeling software like Blender or Rhino Grasshopper which provides a programmable interface, resulting in finely and easily editable 3D models. To evaluate the proposed model, we created two datasets: one featuring simple scenes and another with complex scenes. The test results demonstrate the model's ability to accurately reconstruct simple scenes but reveal its challenges with more complex ones.
    Keywords Computer Science - Computer Vision and Pattern Recognition
    Subject code 004
    Publishing date 2023-09-28
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: aPKC

    Yang Hong

    F1000Research, Vol

    the Kinase that Phosphorylates Cell Polarity [version 1; referees: 2 approved]

    2018  Volume 7

    Abstract: Establishing and maintaining cell polarity are dynamic processes that necessitate complicated but highly regulated protein interactions. Phosphorylation is a powerful mechanism for cells to control the function and subcellular localization of a target ... ...

    Abstract Establishing and maintaining cell polarity are dynamic processes that necessitate complicated but highly regulated protein interactions. Phosphorylation is a powerful mechanism for cells to control the function and subcellular localization of a target protein, and multiple kinases have played critical roles in cell polarity. Among them, atypical protein kinase C (aPKC) is likely the most studied kinase in cell polarity and has the largest number of downstream substrates characterized so far. More than half of the polarity proteins that are essential for regulating cell polarity have been identified as aPKC substrates. This review covers mainly studies of aPKC in regulating anterior-posterior polarity in the worm one-cell embryo and apical-basal polarity in epithelial cells and asymmetrically dividing cells (for example, Drosophila neuroblasts). We will go through aPKC target proteins in cell polarity and discuss various mechanisms by which aPKC phosphorylation controls their subcellular localizations and biological functions. We will also review the recent progress in determining the detailed molecular mechanisms in spatial and temporal control of aPKC subcellular localization and kinase activity during cell polarization.
    Keywords Medicine ; R ; Science ; Q
    Subject code 571
    Language English
    Publishing date 2018-06-01T00:00:00Z
    Publisher F1000 Research Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: Electroconvulsive therapy and muscle relaxants.

    Yang, Hong Seuk / Joung, Kyoung-Woon

    Anesthesia and pain medicine

    2023  Volume 18, Issue 4, Page(s) 447–448

    Language English
    Publishing date 2023-07-14
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2383-7977
    ISSN (online) 2383-7977
    DOI 10.17085/apm.23018
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top