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  1. Article ; Online: Adipose tissue indices predict prognosis in hodgkin lymphoma.

    Özbalcı, Demircan / Erdoğan, Mehmet / Alanoğlu, Emine Güçhan / Şengül, Sevim Süreyya / Yüceer, Kamuran / Eroğlu, Hande Nur / Yağcı, Samet

    Leukemia research

    2024  Volume 138, Page(s) 107457

    Abstract: Introduction background: This study evaluated the impact of adipose tissue indices on prognosis of HL.: Methods: Fifty-five patients with newly diagnosed Hodgkin Lymphoma were evaluated retrospectively for association with adipose tissue indices ( ... ...

    Abstract Introduction background: This study evaluated the impact of adipose tissue indices on prognosis of HL.
    Methods: Fifty-five patients with newly diagnosed Hodgkin Lymphoma were evaluated retrospectively for association with adipose tissue indices (total abdominal tissue volume, radiodensity, subcutaneous and visceral adipose tissue SUVmax value and prognostic factors for Hodgkin Lymphoma such as IPS-3, IPS-7, stage, sedimentation, progression free and overall survival.
    Results: For IPS-3, SAT SUVmax and TAAT radiodensity were significantly increased in high-risk patients (2and 3) compared to group 0 and 1. For IPS-7, total abdominal adipose volume was significantly decreased in high-risk patients, SAT SUVmax significantly increased in high-risk patients and decreased in low-risk patients. In addition, SAT SUVmax was significantly increased in patients with high sedimentation rate, with B symptoms and who passed away during follow-up. SAT SUVmax showed moderate positive correlation with sedimentation, IPS-3, IPS-7, and stage. In addition, it was observed that TAAT radiodensity and SAT SUVmax were significantly better for determining prognosis than other adipose tissue indices. Roc analysis showed that the diagnostic value of all adipose tissue indices in predicting IPS-3 and IPS-7 prognoses were statistically significant.
    Conclusion: SAT SUVmax and TAAT radiodensity were two new and independent markers with diagnostic value in predicting prognosis.
    MeSH term(s) Humans ; Hodgkin Disease/diagnostic imaging ; Retrospective Studies ; Disease-Free Survival ; Prognosis ; Adipose Tissue/diagnostic imaging
    Language English
    Publishing date 2024-02-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 752396-8
    ISSN 1873-5835 ; 0145-2126
    ISSN (online) 1873-5835
    ISSN 0145-2126
    DOI 10.1016/j.leukres.2024.107457
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The role of Ga

    Erdogan, Mehmet / Sengul, Sevim S / Cetin, Bulent / Avcı, Mustafa / Yagci, Samet / Ozkoç, Ismail / Barikan, Damla Ezgi / Yildiz, Mustafa

    Annals of nuclear medicine

    2022  Volume 36, Issue 6, Page(s) 562–569

    Abstract: Objective: Lutetium-177 (Lu: Methods: These single-center retrospective data were obtained from metastatic CRPC patients receiving intravenous 6.0-8.5 GBq Lu: Results: It was found that SUVmax, PSMA TV, and TL PSMA values in bone metastases showed ...

    Abstract Objective: Lutetium-177 (Lu
    Methods: These single-center retrospective data were obtained from metastatic CRPC patients receiving intravenous 6.0-8.5 GBq Lu
    Results: It was found that SUVmax, PSMA TV, and TL PSMA values in bone metastases showed significant differences between the groups with decreased and increased PSMA expression levels after the treatment. The AUC value for SUVmax was significant (AUC = 0.677; p < 0.001). The cutoff value was > 10.50 (sensitivity = 91.8%, Specificity = 41.5%) for SUVmax, > 1.50 cm
    Conclusion: It was shown in the present study that Lu
    MeSH term(s) Bone Neoplasms/diagnostic imaging ; Bone Neoplasms/therapy ; Gallium Radioisotopes/therapeutic use ; Heterocyclic Compounds, 1-Ring/therapeutic use ; Humans ; Lutetium/therapeutic use ; Lymphatic Metastasis ; Male ; Positron Emission Tomography Computed Tomography ; Prostate-Specific Antigen ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Prostatic Neoplasms, Castration-Resistant/therapy ; Retrospective Studies ; Treatment Outcome
    Chemical Substances Gallium Radioisotopes ; Heterocyclic Compounds, 1-Ring ; Lutetium (5H0DOZ21UJ) ; Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2022-04-09
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1146984-5
    ISSN 1864-6433 ; 0914-7187
    ISSN (online) 1864-6433
    ISSN 0914-7187
    DOI 10.1007/s12149-022-01739-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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