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  1. Article ; Online: Magnetic Resonance Imaging and Cardiac Devices.

    Yadava, Mrinal / Henrikson, Charles A

    The New England journal of medicine

    2018  Volume 378, Issue 17, Page(s) 1652

    MeSH term(s) Heart ; Humans ; Magnetic Resonance Imaging
    Language English
    Publishing date 2018--26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc1802623
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  2. Article ; Online: Effect of Additionally Integrating Clinical Information Into the Brugada Algorithm.

    Moccetti, Federico / Brugada, Pedro / Tersalvi, Gregorio / Yadava, Mrinal / Latifi, Yllka / Berte, Benjamin / Kobza, Richard / Sticherling, Christian / Reichlin, Tobias

    JACC. Clinical electrophysiology

    2023  Volume 9, Issue 6, Page(s) 868–870

    Language English
    Publishing date 2023-02-22
    Publishing country United States
    Document type Letter
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2022.12.017
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  3. Article ; Online: Reply.

    Yadava, Mrinal / Heitner, Stephen B / Song, Howard K

    The Annals of thoracic surgery

    2019  Volume 109, Issue 2, Page(s) 618

    MeSH term(s) Cardiomyopathy, Hypertrophic ; Humans ; Papillary Muscles
    Language English
    Publishing date 2019-07-03
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2019.05.033
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    Zs.A 252: Show issues Location:
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  4. Article ; Online: Reply.

    Yadava, Mrinal / Heitner, Stephen B / Song, Howard K

    The Annals of thoracic surgery

    2019  Volume 107, Issue 6, Page(s) 1912

    MeSH term(s) Cardiomyopathy, Hypertrophic ; Humans ; Papillary Muscles
    Language English
    Publishing date 2019-03-16
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2019.02.020
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  5. Article: Applications of Advanced Imaging in Cardiac Electrophysiology.

    Yadava, Mrinal / Shapiro, Michael D

    Current treatment options in cardiovascular medicine

    2016  Volume 18, Issue 11, Page(s) 66

    Abstract: Opinion statement: Imaging modalities such as computed tomography, magnetic resonance, positron emission tomography, and single-photon emission computed tomography are an indispensable component of cardiac arrhythmia management. Over the last two ... ...

    Abstract Opinion statement: Imaging modalities such as computed tomography, magnetic resonance, positron emission tomography, and single-photon emission computed tomography are an indispensable component of cardiac arrhythmia management. Over the last two decades, developments in imaging techniques have facilitated safer and more effective cardiac ablation and device implantation procedures. Pre-procedural assessment of arrhythmogenic substrate and integration with electroanatomic data has significantly impacted the management of atrial fibrillation and ventricular tachycardia. Furthermore, cardiovascular imaging enhances patient selection, prognostication, and follow-up of patients undergoing ablation procedures. Imaging also provides valuable anatomic information in patients being considered for cardiac resynchronization therapy (CRT). While the optimal modality for assessing efficacy of resynchronization is currently unclear, further study holds promise in mitigating the substantial burden of CRT non-response. This article aims to highlight the utility and evidence for various advanced imaging modalities in the practice of cardiac electrophysiology with an emphasis on recent developments and future directions.
    Language English
    Publishing date 2016-09-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2057337-6
    ISSN 1534-3189 ; 1092-8464
    ISSN (online) 1534-3189
    ISSN 1092-8464
    DOI 10.1007/s11936-016-0491-5
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    Zs.A 5529: Show issues Location:
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  6. Article: Electrophysiological correlates of cardiac sarcoidosis: an appraisal of current evidence.

    Yadava, Mrinal / Bala, Rupa

    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir

    2015  Volume 43, Issue 4, Page(s) 392–401

    Abstract: Cardiac sarcoidosis is an underdiagnosed condition that may be present in as many as 25% of patients with systemic sarcoidosis. It is associated with significant morbidity and mortality in affected individuals. The presentation of cardiac involvement in ... ...

    Abstract Cardiac sarcoidosis is an underdiagnosed condition that may be present in as many as 25% of patients with systemic sarcoidosis. It is associated with significant morbidity and mortality in affected individuals. The presentation of cardiac involvement in sarcoidosis includes sudden death in the absence of preceding symptoms, conduction disturbances, ventricular arrhythmias, and heart failure. A scarcity of randomized data and a lack of prospective trials underlies the contention between experts on the most appropriate strategies for diagnosis and therapy. This review focuses on the electrophysiological sequelae of the disease, with an emphasis on current diagnostic guidelines, multimodality imaging for early detection, and the role of various therapeutic interventions. Multicentre collaboration is necessary to address the numerous unanswered questions pertaining to management of this disease.
    MeSH term(s) Adolescent ; Adult ; Cardiac Imaging Techniques ; Cardiomyopathies/diagnosis ; Cardiomyopathies/epidemiology ; Cardiomyopathies/therapy ; Electrocardiography ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Sarcoidosis/diagnosis ; Sarcoidosis/epidemiology ; Sarcoidosis/therapy ; Young Adult
    Language English
    Publishing date 2015-06
    Publishing country Turkey
    Document type Journal Article ; Review
    ZDB-ID 1215217-1
    ISSN 1308-4488 ; 1016-5169
    ISSN (online) 1308-4488
    ISSN 1016-5169
    DOI 10.5543/tkda.2015.53333
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    Zs.A 4156: Show issues Location:
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  7. Article: Postoperative Atrial Fibrillation: Incidence, Mechanisms, and Clinical Correlates.

    Yadava, Mrinal / Hughey, Andrew B / Crawford, Thomas Christopher

    Heart failure clinics

    2016  Volume 12, Issue 2, Page(s) 299–308

    Abstract: Atrial fibrillation is the most commonly encountered arrhythmia after cardiac surgery. Although usually self-limiting, it represents an important predictor of increased patient morbidity, mortality, and health care costs. Numerous studies have attempted ... ...

    Abstract Atrial fibrillation is the most commonly encountered arrhythmia after cardiac surgery. Although usually self-limiting, it represents an important predictor of increased patient morbidity, mortality, and health care costs. Numerous studies have attempted to determine the underlying mechanisms of postoperative atrial fibrillation (POAF) with varied success. A multifactorial pathophysiology is hypothesized, with inflammation and postoperative β-adrenergic activation recognized as important contributing factors. The management of POAF is complicated by a paucity of data relating to the outcomes of different therapeutic interventions in this population. This article reviews the literature on epidemiology, mechanisms, and risk factors of POAF, with a subsequent focus on the therapeutic interventions and guidelines regarding management.
    MeSH term(s) Anticoagulants/therapeutic use ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/economics ; Atrial Fibrillation/epidemiology ; Atrial Fibrillation/physiopathology ; Cardiac Surgical Procedures/adverse effects ; Cardiovascular Diseases/complications ; Coronary Artery Bypass/adverse effects ; Humans ; Incidence ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/prevention & control ; Thromboembolism/epidemiology ; Thromboembolism/prevention & control
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2016-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2212019-1
    ISSN 1551-7136
    ISSN 1551-7136
    DOI 10.1016/j.hfc.2015.08.023
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    Zs.A 6554: Show issues Location:
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  8. Article ; Online: Simplified Integrated Clinical and Electrocardiographic Algorithm for Differentiation of Wide QRS Complex Tachycardia: The Basel Algorithm.

    Moccetti, Federico / Yadava, Mrinal / Latifi, Yllka / Strebel, Ivo / Pavlovic, Nikola / Knecht, Sven / Asatryan, Babken / Schaer, Beat / Kühne, Michael / Henrikson, Charles A / Stephan, Frank-Peter / Osswald, Stefan / Sticherling, Christian / Reichlin, Tobias

    JACC. Clinical electrophysiology

    2022  Volume 8, Issue 7, Page(s) 831–839

    Abstract: Background: Prompt differential diagnosis of wide QRS complex tachycardia (WCT) is crucial to patient management. However, distinguishing ventricular tachycardia (VT) from supraventricular tachycardia (SVT) with wide QRS complexes remains problematic, ... ...

    Abstract Background: Prompt differential diagnosis of wide QRS complex tachycardia (WCT) is crucial to patient management. However, distinguishing ventricular tachycardia (VT) from supraventricular tachycardia (SVT) with wide QRS complexes remains problematic, especially for nonelectrophysiologists.
    Objectives: This study aimed to develop a simple-to-use algorithm with integration of clinical and electrocardiographic (ECG) parameters for the differential diagnosis of WCT.
    Methods: The 12-lead ECGs of 206 monomorphic WCTs (153 VT, 53 SVT) with electrophysiology-confirmed diagnoses were analyzed. In the novel Basel algorithm, VT was diagnosed in the presence of at least 2 of the following criteria: 1) clinical high risk features; 2) lead II time to first peak >40 ms; and 3) lead aVR time to first peak >40 ms. The algorithm was externally validated in 203 consecutive WCT cases (151 VT, 52 SVT). Its' diagnostic performance and clinical applicability were compared with those of the Brugada and Vereckei algorithms.
    Results: The Basel algorithm showed a sensitivity, specificity, and accuracy of 92%, 89%, and 91%, respectively, in the derivation cohort and 93%, 90%, and 93%, respectively, in the validation cohort. There were no significant differences in the performance characteristics between the 3 algorithms. The evaluation of the clinical applicability of the Basel algorithm showed similar diagnostic accuracy compared with the Brugada algorithm (80% vs 81%; P = 1.00), but superiority compared with the Vereckei algorithm (72%; P = 0.03). The Basel algorithm, however, enabled a faster diagnosis (median 36 seconds vs 105 seconds for the Brugada algorithm [P = 0.002] and 50 seconds for the Vereckei algorithm [P = 0.02]).
    Conclusions: The novel Basel algorithm based on simple clinical and ECG criteria allows for a rapid and accurate differential diagnosis of WCT.
    MeSH term(s) Algorithms ; Diagnosis, Differential ; Electrocardiography ; Humans ; Tachycardia, Supraventricular/diagnosis ; Tachycardia, Ventricular/diagnosis
    Language English
    Publishing date 2022-05-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2022.03.017
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  9. Article ; Online: Postoperative atrial fibrillation: incidence, mechanisms, and clinical correlates.

    Yadava, Mrinal / Hughey, Andrew B / Crawford, Thomas Christopher

    Cardiology clinics

    2014  Volume 32, Issue 4, Page(s) 627–636

    Abstract: Atrial fibrillation is the most commonly encountered arrhythmia after cardiac surgery. Although usually self-limiting, it represents an important predictor of increased patient morbidity, mortality, and health care costs. Numerous studies have attempted ... ...

    Abstract Atrial fibrillation is the most commonly encountered arrhythmia after cardiac surgery. Although usually self-limiting, it represents an important predictor of increased patient morbidity, mortality, and health care costs. Numerous studies have attempted to determine the underlying mechanisms of postoperative atrial fibrillation (POAF) with varied success. A multifactorial pathophysiology is hypothesized, with inflammation and postoperative β-adrenergic activation recognized as important contributing factors. The management of POAF is complicated by a paucity of data relating to the outcomes of different therapeutic interventions in this population. This article reviews the literature on epidemiology, mechanisms, and risk factors of POAF, with a subsequent focus on the therapeutic interventions and guidelines regarding management.
    MeSH term(s) Anticoagulants/therapeutic use ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Atrial Fibrillation/etiology ; Atrial Fibrillation/prevention & control ; Cardiovascular Agents/therapeutic use ; Humans ; Incidence ; Postoperative Complications/epidemiology ; Postoperative Complications/prevention & control ; Prognosis ; Risk Assessment ; Risk Factors ; Surgical Procedures, Operative/adverse effects ; Surgical Procedures, Operative/methods ; Thromboembolism/epidemiology ; Thromboembolism/etiology ; Thromboembolism/prevention & control
    Chemical Substances Anticoagulants ; Cardiovascular Agents
    Language English
    Publishing date 2014-11
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1196385-2
    ISSN 1558-2264 ; 0733-8651
    ISSN (online) 1558-2264
    ISSN 0733-8651
    DOI 10.1016/j.ccl.2014.07.002
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  10. Article ; Online: Magnetic resonance imaging in patients with cardiac implantable electronic devices: a single-center prospective study.

    Yadava, Mrinal / Nugent, Matthew / Krebsbach, Angela / Minnier, Jessica / Jessel, Peter / Henrikson, Charles A

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2017  Volume 50, Issue 1, Page(s) 95–104

    Abstract: Purpose: Cardiac implantable electronic devices (CIEDs) have traditionally been a contraindication for magnetic resonance imaging (MRI). Recent studies suggest that MRI can be conducted safely in select patients with pacemakers (PPMs) and implantable ... ...

    Abstract Purpose: Cardiac implantable electronic devices (CIEDs) have traditionally been a contraindication for magnetic resonance imaging (MRI). Recent studies suggest that MRI can be conducted safely in select patients with pacemakers (PPMs) and implantable cardioverter defibrillators (ICDs). We sought to determine the safety of MRI in patients with CIEDs, using a protocol for patient selection and device programming.
    Methods: This is a prospective, single-center study. Patients with a PPM or ICD and a clinical indication for MRI were considered. Exclusion criteria included newly implanted devices (<4 weeks), PPMs manufactured before 1996 and ICDs before 2000, epicardial and abandoned leads, and pacemaker-dependent ICD patients. Pacemaker-dependent PPM patients were programmed to asynchronous pacing. Tachycardia detection/therapies were disabled for ICDs. Devices were interrogated pre- and post-scan, and at follow-up 1-6 weeks later. Defibrillation threshold (DFT) was not tested post-scan. Patients were followed to monitor device therapies.
    Results: Two hundred twenty-seven patients underwent 293 scans. Devices included 170 (70.6%) PPMs and 71 (29.5%) ICDs. Thirteen (4.4%) scans were aborted mainly due to subjective complaints or artifact on scout cardiac imaging. Post-scan and follow-up interrogation demonstrated no changes in device parameters requiring reprogramming or revision. Over long-term follow-up (median, 354 days [IQR 65-629]), nine ICD patients had appropriate shocks (median, 3 [IQR 1-8]). One had four inappropriate shocks for atrial fibrillation. All tachyarrhythmias meeting criteria for defibrillation were successfully terminated.
    Conclusions: MRI can be conducted safely in patients with CIEDs when done in a protocoled manner with appropriate supervision. DFT testing after MRI may not be necessary.
    MeSH term(s) Aged ; Cohort Studies ; Defibrillators, Implantable/utilization ; Equipment Design ; Equipment Failure Analysis ; Equipment Safety ; Female ; Follow-Up Studies ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Monitoring, Physiologic/methods ; Prospective Studies ; Time Factors
    Language English
    Publishing date 2017-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-017-0262-6
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