LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 50

Search options

  1. Article ; Online: Consumers' misevaluation and public promotion

    Yamagishi, Atsushi

    The B.E. journal of economic analysis & policy Vol. 16, No. 4 , p. 1-5

    2016  Volume 16, Issue 4, Page(s) 1–5

    Author's details AtsushiYamagishi
    Keywords consumers' misevaluation ; excess entry ; public promotion
    Language English
    Size Online-Ressource
    Publisher De Gruyter
    Publishing place Berlin
    Document type Article ; Online
    ZDB-ID 2268326-4
    ISSN 1935-1682
    DOI 10.1515/bejeap-2016-0141
    Database ECONomics Information System

    More links

    Kategorien

  2. Article: Delivery of Low-Diluted Toothpaste during Brushing Improves Enamel Acid Resistance.

    Satou, Ryouichi / Shibata, Chikara / Takayanagi, Atsushi / Yamagishi, Atsushi / Birkhed, Dowen / Sugihara, Naoki

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 14

    Abstract: Toothpaste viscosity decreases rapidly when diluted with saliva during brushing, potentially causing premature washout of high-risk caries areas and reducing the uptake of dental fluoride ions. However, no reports have examined the acid resistance of ... ...

    Abstract Toothpaste viscosity decreases rapidly when diluted with saliva during brushing, potentially causing premature washout of high-risk caries areas and reducing the uptake of dental fluoride ions. However, no reports have examined the acid resistance of enamel from the perspective of the toothpaste's physical properties. This study aimed to elucidate the impact of toothpaste dilution on the acid resistance of the enamel, using bovine enamel as the subject. Five diluted toothpaste groups were created: a control group without toothpaste, and 100% (1.00×), 67% (1.50×), 50% (2.00×), and 25% (4.00×) dilution groups. Acid resistance was evaluated through pH cycling after toothpaste application. The results revealed a significant increase in substantial defects, compared to 67% (1.50×) at dilutions of 50% (2.00×) or higher, accompanied by a decrease in Vickers hardness. Moreover, the mineral loss increased with dilution, and a significant difference was observed between 67% (1.50×) and 50% (2.00×) (
    Language English
    Publishing date 2023-07-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16145089
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Prednisolone Treatment Is Effective for an Idiopathic Penile Abscess: A Case Report and Review.

    Yamagishi, Atsushi / Kurokawa, Masayuki / Nishida, Hayato / Konno, Takayuki / Tsuchiya, Norihiko

    The American journal of case reports

    2021  Volume 22, Page(s) e933618

    Abstract: BACKGROUND Penile abscesses were traditionally regarded as an infectious disease; however, idiopathic cases in which prednisolone was effective have been reported. CASE REPORT A 64-year-old man was admitted to the hospital with symptoms of penile ... ...

    Abstract BACKGROUND Penile abscesses were traditionally regarded as an infectious disease; however, idiopathic cases in which prednisolone was effective have been reported. CASE REPORT A 64-year-old man was admitted to the hospital with symptoms of penile induration and dysuria. He was diagnosed with a penile abscess, which was punctured and then relapsed. An incision and drainage were performed on the abscess, and the pus and tissue samples were cultured and examined histologically. There was no evidence of malignancy or bacterial infection, and he was diagnosed with an idiopathic penile abscess. As pus continuously drained from the incision, prednisolone 40 mg was initiated, which resulted in a decreased amount of pus and eventual wound closure. Over 15 months, prednisolone was gradually tapered to 5 mg, and the abscess continued to decrease in size. CONCLUSIONS Idiopathic penile abscesses are rare but often lead to penectomy. Prednisolone is a new treatment method for such patients. This is the third case of an idiopathic penile abscess that was successfully treated with prednisolone. The causative agent of the idiopathic penile abscess was suggested to be pyoderma gangrenosum; however, this case did not exhibit the typical characteristics of pyoderma gangrenosum. Therefore, further investigation was needed. A differential diagnosis of an infectious abscess is required before initiating steroid treatment. Open drainage is useful, but the size of the incision should be minimized for the purpose of preserving penile function. The prednisolone dose should be started at 20 to 40 mg and reduced gradually to avoid relapse.
    MeSH term(s) Abscess/drug therapy ; Diagnosis, Differential ; Drainage ; Humans ; Male ; Middle Aged ; Prednisolone/therapeutic use ; Pyoderma Gangrenosum/diagnosis
    Chemical Substances Prednisolone (9PHQ9Y1OLM)
    Language English
    Publishing date 2021-11-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.933618
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: A case of Noonan syndrome with skull defect due to vitamin D deficiency rickets.

    Nagara, Syunsuke / Usui, Shinji / Kawashiri, Miwa / Kondo, Masashi / Yamagishi, Atsushi

    Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology

    2021  Volume 30, Issue 1, Page(s) 71–73

    Abstract: We report the case of a boy with partial skull defects in addition to widespread craniotabes due to vitamin D deficiency rickets. He was born at 30 wk and 4 d of gestation (birth weight, 2406 g). At 77 d of age, clinical examination of the head revealed ... ...

    Abstract We report the case of a boy with partial skull defects in addition to widespread craniotabes due to vitamin D deficiency rickets. He was born at 30 wk and 4 d of gestation (birth weight, 2406 g). At 77 d of age, clinical examination of the head revealed widespread craniotabes of the occipital region centered around the lambda suture, and palpation revealed a defect of about 1 cm in the parietal bone of the left occipital region. Cranial computed tomography showed thinning of the cortex and bone defects in the parietal bones bilaterally, as well as in the left occipital bone. At 3 mo of age, he was diagnosed with vitamin D deficiency rickets and was administered alfacalcidol for 4 mo. Although patients with vitamin D deficiency rickets are prone to fractures, bone defects, as in this case, have not been reported. In addition to vitamin D deficiency rickets, the causes of the bone defects, in this case, are hypothesized to be abnormalities in the Ras-mitogen activated protein kinase pathway associated with Noonan syndrome, and long-term compression of the back of the head. However, there are no other similar reports, and further ones need to be accumulated.
    Language English
    Publishing date 2021-01-05
    Publishing country Japan
    Document type Case Reports
    ZDB-ID 2079760-6
    ISSN 0918-5739
    ISSN 0918-5739
    DOI 10.1297/cpe.30.71
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Polarization of infiltrating macrophages in the outer annulus fibrosus layer associated with the process of intervertebral disc degeneration and neural ingrowth in the human cervical spine.

    Yamagishi, Atsushi / Nakajima, Hideaki / Kokubo, Yasuo / Yamamoto, Yusuke / Matsumine, Akihiko

    The spine journal : official journal of the North American Spine Society

    2021  Volume 22, Issue 5, Page(s) 877–886

    Abstract: Background context: As no infiltrating macrophages exist in healthy discs, understanding the role of infiltrating macrophages including their polarity (M1 and M2 phenotypes) in intervertebral discs (IVDs) is important in the assessment of the ... ...

    Abstract Background context: As no infiltrating macrophages exist in healthy discs, understanding the role of infiltrating macrophages including their polarity (M1 and M2 phenotypes) in intervertebral discs (IVDs) is important in the assessment of the pathomechanisms of disc degeneration.
    Purpose: To determine the relationship between infiltrating macrophage polarization and the progression of human cervical IVD degeneration.
    Study design: Histopathological study using harvested human cervical IVDs.
    Methods: IVDs collected during anterior cervical decompression from 60 patients were subjected to immunostaining and immunoblotting. The samples were classified as type 0-3 according to the percentage of CD16- and CD206-positive cells to CD68-positive cells in the outer annulus fibrosus layer. The number of vessels and nerve fibers and the severity of chronic inflammation with a focus on inflammatory cell infiltration, fibrosis, and capillary proliferation were also assessed.
    Results: The number of CD16-positive cells was the highest in type 2 IVDs, and was suppressed following the infiltration of CD206-positive cells. The degree of chronic inflammation was significantly higher in type 2 and type 3 IVDs, and the number of nerve fibers was significantly higher in type 3 IVDs. The endothelial cells of small vessels were positive for nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 expression. Staining for tropomyosin receptor kinase (Trk)-A, Trk-B, and Trk-C was positive in aberrant fibers. In immunoblot analysis, the expression levels of these neurotrophic factors and receptors were significantly higher in type 2 and 3 IVDs.
    Conclusions: The polarity of macrophages around newly developed microvasculature might be altered with cervical IVD degeneration. A higher number of infiltrating M1 macrophages around the vessels was associated with chronic inflammation; however, their number got suppressed following the infiltration of M2 macrophages. The expression of neurotrophins in the capillaries of small vessels might contribute to neural ingrowth into degenerated IVDs.
    Clinical significance: Clarifying macrophages polarity change around new microvasculature associated with progression of IVD degeneration could enhance our understanding of the underlying mechanisms of neural ingrowth into degenerated IVDs and lead to development of a novel therapeutic target for prevention of IVD.
    MeSH term(s) Annulus Fibrosus/metabolism ; Cervical Vertebrae/pathology ; Endothelial Cells/metabolism ; Humans ; Inflammation/metabolism ; Intervertebral Disc/metabolism ; Intervertebral Disc Degeneration/pathology ; Macrophages/metabolism
    Language English
    Publishing date 2021-12-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2037072-6
    ISSN 1878-1632 ; 1529-9430
    ISSN (online) 1878-1632
    ISSN 1529-9430
    DOI 10.1016/j.spinee.2021.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Improved Enamel Acid Resistance by Highly Concentrated Acidulated Phosphate Sodium Monofluorophosphate Solution.

    Satou, Ryouichi / Yamagishi, Atsushi / Takayanagi, Atsushi / Iwasaki, Miyu / Kamijo, Hideyuki / Sugihara, Naoki

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 20

    Abstract: Sodium monofluorophosphate (MFP) is a component of fluoride-containing dentifrices and is more biosafe than the conventional sodium fluoride (NaF). MFP can respond not only on the tooth surface layer but also deep into the enamel. We aim to confirm that ... ...

    Abstract Sodium monofluorophosphate (MFP) is a component of fluoride-containing dentifrices and is more biosafe than the conventional sodium fluoride (NaF). MFP can respond not only on the tooth surface layer but also deep into the enamel. We aim to confirm that high concentrations of acid phosphate MFP (AP-MFP, 9000 ppmF), used in professional care, could lead to a highly biosafe fluoride application method that acts through the deep enamel layers. Sample groups were respectively treated in vitro with NaF, acidulated phosphate fluoride (APF), MFP, and AP-MFP, and the samples were compared against an untreated group. Characterizations after fluoride application confirmed that MFP and AP-MFP treatments improved the acid resistance of enamel compared to that of conventional methods. Furthermore, the acid resistance of highly concentrated MFPs improved by using phosphoric acid. Although the acid resistance from the AP-MFP method is not as good as that using APF, AP-MFP can act both on the surface layer and deep into the enamel. Moreover, AP-MFP retains fluoride ions as much as APF does on the tooth surface. The proposed fluoride application method using AP-MFP introduces a dental treatment for acid resistance that is highly biosafe and penetrates deep layers of the enamel.
    Language English
    Publishing date 2022-10-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15207298
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Comparison of interproximal delivery and flow characteristics by dentifrice dilution and application of prepared toothpaste delivery technique.

    Satou, Ryouichi / Yamagishi, Atsushi / Takayanagi, Atsushi / Suzuki, Seitaro / Birkhed, Dowen / Sugihara, Naoki

    PloS one

    2022  Volume 17, Issue 10, Page(s) e0276227

    Abstract: In home care, the toothpaste technique, which can enhance the caries-preventive effect without changing the amount of dentifrice and fluoride ion concentration, is of great significance. This study aimed to construct a model and experimental system that ... ...

    Abstract In home care, the toothpaste technique, which can enhance the caries-preventive effect without changing the amount of dentifrice and fluoride ion concentration, is of great significance. This study aimed to construct a model and experimental system that reproduces the interdental part and to clarify the relationship between the change in dentifrice viscosity due to dilution and washout in the high-risk approximal area of caries. Additionally, the effectiveness of the toothpaste technique and appropriate devices for delivering dentifrice to the interdental area at a low dilution were investigated. Diluted toothpaste samples were prepared (: ×1.00, ×1.25, ×1.50, ×1.75, ×2.00, ×3.00, and ×4.00). An acrylic interproximal model was created for this experiment. The flow characteristics and viscosity by dentifrice dilution were measured. In the case of low dilution of 57% (1.75×) or more, it was shown that the dentifrice in the high-risk area may be washed out early because of the decrease in viscosity, and the caries-preventive effect may be reduced. It was also suggested that to keep the dentifrice in the interdental area for 120 s at the end of brushing, a dilution must be devised to a concentration of at least 50% (2.00×). The prepared toothpaste delivery (PTD) method of delivering dentifrice to the interdental area while maintaining it at a low dilution is an effective toothpaste technique in terms of dentifrice dilution and viscosity. The use of finger brushes in the PTD method could increase the efficiency of dentifrice delivery.
    MeSH term(s) Dentifrices ; Fluorides ; Indicator Dilution Techniques ; Sodium Fluoride ; Toothbrushing/methods ; Toothpastes
    Chemical Substances Dentifrices ; Toothpastes ; Sodium Fluoride (8ZYQ1474W7) ; Fluorides (Q80VPU408O)
    Language English
    Publishing date 2022-10-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0276227
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Relationship between Toothpaste Dilution Ratio and Droplets Generated during Tooth-Brushing.

    Satou, Ryouichi / Yamagishi, Atsushi / Takayanagi, Atsushi / Higuchi, Takuro / Oyama, Tsutomu / Suzuki, Seitaro / Sugihara, Naoki

    International journal of environmental research and public health

    2022  Volume 19, Issue 7

    Abstract: Guidelines for using toothpaste during tooth-brushing in public places during the coronavirus epidemic are lacking. In addition, the advantages and disadvantages of using toothpaste in terms of droplet generation during brushing, the number of droplets ... ...

    Abstract Guidelines for using toothpaste during tooth-brushing in public places during the coronavirus epidemic are lacking. In addition, the advantages and disadvantages of using toothpaste in terms of droplet generation during brushing, the number of droplets generated, and their scatter range are unknown; therefore, we investigated the relationships between diluted toothpaste viscosity, the number of droplets generated, and the droplets' flight distance. We developed a system to quantitate droplet generation during tooth-brushing. Brushing with water generated 5965 ± 266 droplets; 10.0× diluted toothpaste generated 538 ± 56, 4.00× diluted toothpaste generated 349 ± 15, and 2.00× diluted toothpaste generated 69 ± 27 droplets. Undiluted toothpaste generated no droplets. Droplet number tended to increase with increased toothpaste dilution ratio and decreased viscosity (
    MeSH term(s) Indicator Dilution Techniques ; Toothbrushing ; Toothpastes ; Water
    Chemical Substances Toothpastes ; Water (059QF0KO0R)
    Language English
    Publishing date 2022-03-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19074157
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Lobbying for regulation reform by industry leaders

    Matsumura, Toshihiro / Yamagishi, Atsushi

    Journal of regulatory economics Vol. 52, No. 1 , p. 63-76

    2017  Volume 52, Issue 1, Page(s) 63–76

    Author's details Toshihiro Matsumura, Atsushi Yamagishi
    Keywords Lobbying ; Common costs ; Free-entry market ; Stackelberg ; Regulation costs
    Language English
    Publisher Springer
    Publishing place Norwell, Mass. [u.a.]
    Document type Article
    ZDB-ID 1027173-9 ; 1478739-8
    ISSN 1573-0468 ; 0922-680X
    ISSN (online) 1573-0468
    ISSN 0922-680X
    Database ECONomics Information System

    More links

    Kategorien

  10. Article: Long-run welfare effect of energy conservation regulation

    Matsumura, Toshihiro / Yamagishi, Atsushi

    Economics letters Vol. 154 , p. 64-68

    2017  Volume 154, Page(s) 64–68

    Author's details Toshihiro Matsumura, Atsushi Yamagishi
    Keywords Energy-saving ; Environmental tax ; Free entry market ; Consumer-benefiting regulation
    Language English
    Publisher Elsevier
    Publishing place Amsterdam [u.a.]
    Document type Article
    ZDB-ID 717210-2
    ISSN 0165-1765
    Database ECONomics Information System

    More links

    Kategorien

To top